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Journal Articles

The NEDD8 Activating Enzyme Inhibitor Pevonedistat Induces ER Stress/UPR-Mediated Cell Death and Rebalances Homeostasis of Pro- and Anti-Apoptotic Proteins in Favor of Cell Death in Acute Lymphoblastic Leukemia Cells

Gilles M. Leclerc, PhD, Shuhua Zheng, BS, Guy J. Leclerc, PhD, Joanna DeSalvo, BSc, Ronan T. Swords, MDPhDFRCPI FRCPath, Julio C. Barredo, MD

Blood (2015) 126 (23): 1327.

https://doi.org/10.1182/blood.V126.23.1327.1327

Published: 2015

Journal Articles

BCR-ABL+ Bp-ALL Exhibits Heightened Sensitivity to Simultaneous Induction of Energy and ER Stress Via Downregulation of Mcl-1 Expression

Guy J. Leclerc, PhD, Joanna DeSalvo, B.Sc., Gilles M. Leclerc, PhD, Theodore J. Lampidis, PhD, Julio C. Barredo, MD

Blood (2014) 124 (21): 916.

https://doi.org/10.1182/blood.V124.21.916.916

Published: 2014

Journal Articles

The BCR-ABL Fusion Protein Sensitizes Acute Lymphoblastic Leukemia to Apoptotic Death Induced by the Dual Glycolytic and Glycosylation Inhibitor 2-Deoxy-D-Glucose.

Guy J Leclerc, Ph.D., Jianfeng Du, Ph.D., Joanna DeSalvo, B.Sc., Gilles M. Leclerc, Ph.D., Julio C. Barredo, M.D.

Blood (2012) 120 (21): 2439.

https://doi.org/10.1182/blood.V120.21.2439.2439

Published: 2012

Journal Articles

Inhibition of Akt Increases the Sensitivity of Acute Lymphoblastic Leukemia (ALL) to the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG)

Jianfeng Du, Ph.D., Joanna DeSalvo, B.Sc., Antti Muranen, B.Sc., Carlos T. Moraes, Ph.D., Julio C. Barredo, M.D.

Blood (2010) 116 (21): 3254.

https://doi.org/10.1182/blood.V116.21.3254.3254

Published: 2010

Journal Articles

Mechanisms of Sensitivity of B-Precursor, T-Lineage and BCR/ABL Positive Acute Lymphoblastic Leukemia (ALL) to the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG).

Jianfeng Du, Ph.D., Joanna DeSalvo, Julio C Barredo, M.D.

Blood (2009) 114 (22): 3081.

https://doi.org/10.1182/blood.V114.22.3081.3081

Published: 2009

NARROW

The NEDD8 Activating Enzyme Inhibitor Pevonedistat Induces ER Stress/UPR-Mediated Cell Death and Rebalances Homeostasis of Pro- and Anti-Apoptotic Proteins in Favor of Cell Death in Acute Lymphoblastic Leukemia Cells

BCR-ABL+ Bp-ALL Exhibits Heightened Sensitivity to Simultaneous Induction of Energy and ER Stress Via Downregulation of Mcl-1 Expression

The BCR-ABL Fusion Protein Sensitizes Acute Lymphoblastic Leukemia to Apoptotic Death Induced by the Dual Glycolytic and Glycosylation Inhibitor 2-Deoxy-D-Glucose.

Inhibition of Akt Increases the Sensitivity of Acute Lymphoblastic Leukemia (ALL) to the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG)

Mechanisms of Sensitivity of B-Precursor, T-Lineage and BCR/ABL Positive Acute Lymphoblastic Leukemia (ALL) to the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG).

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ASH Publications

American Society of Hematology

The NEDD8 Activating Enzyme Inhibitor Pevonedistat Induces ER Stress/UPR-Mediated Cell Death and Rebalances Homeostasis of Pro- and Anti-Apoptotic Proteins in Favor of Cell Death in Acute Lymphoblastic Leukemia Cells

BCR-ABL+ Bp-ALL Exhibits Heightened Sensitivity to Simultaneous Induction of Energy and ER Stress Via Downregulation of Mcl-1 Expression

The BCR-ABL Fusion Protein Sensitizes Acute Lymphoblastic Leukemia to Apoptotic Death Induced by the Dual Glycolytic and Glycosylation Inhibitor 2-Deoxy-D-Glucose.

Inhibition of Akt Increases the Sensitivity of Acute Lymphoblastic Leukemia (ALL) to the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG)

Mechanisms of Sensitivity of B-Precursor, T-Lineage and BCR/ABL Positive Acute Lymphoblastic Leukemia (ALL) to the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG).

Email alerts

ASH Publications

American Society of Hematology

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