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Jiri Slaby
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Journal Articles

Cereblon (CRBN) Splice Isoform Lacking Exon 10 Attenuates Lenalidomide-Mediated Degradation of Aiolos and Is Upregulated in Immunomodulatory Drugs (IMiDs) Resistant Myeloma (MM) Patients

Ranjan Maity, PhD, Paola E. Neri, MD PhD, Ines Tagoug, PhD, Li Ren, PhD, Jiri Slaby, MD, Victor H Jimenez-Zepeda, MD, Peter Duggan, MD, Justin Simms, Nizar J Bahlis, MD
Journal: Blood
Blood (2014) 124 (21): 639.
https://doi.org/10.1182/blood.V124.21.639.639
Published: 2014
Journal Articles

Transcriptome Profiling of Lenalidomide Treated Myeloma Patients Identifies an Interferon Signature Gene Response and a Novel IRF4/MYC Independent Mechanism of Resistance

Paola E. Neri, MD PhD, Ines Tagoug, PhD, Li Ren, PhD, Ranjan Maity, PhD, Justin Simms, Peter Duggan, MD, Victor H Jimenez-Zepeda, MD, Jiri Slaby, MD, Howie Wu, Jackie Babich, Nizar J Bahlis, MD
Journal: Blood
Blood (2014) 124 (21): 170.
https://doi.org/10.1182/blood.V124.21.170.170
Published: 2014
Journal Articles

Lenalidomide Induced Degradation of Aiolos Disrupts RNA Polimerase I Activity and Ribosomal Biogenesis in Myeloma Cells

Ines Tagoug, PhD, Jiri Slaby, MD, Paola E. Neri, MD PhD, Justin Simms, Jackie Babich, Ranjan Maity, PhD, Li Ren, PhD, Howie Wu, Nizar J Bahlis, MD
Journal: Blood
Blood (2014) 124 (21): 3422.
https://doi.org/10.1182/blood.V124.21.3422.3422
Published: 2014
Journal Articles

Lenalidomide Induces A Ribosomal Stress Response In Multiple Myeloma (MM) Cells

Jiri Slaby, MD, Ines Tagoug, PhD, Paola Neri, MD, PhD, Justin Simms, Jacquelyn Babich, Kathy Gratton, Li Ren, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 3161.
https://doi.org/10.1182/blood.V122.21.3161.3161
Published: 2013
Journal Articles

XPO1 Inhibition Disrupts Ribosomal Subunits Assembly and Induces Multiple Myeloma (MM) Cell Death

Ines Tagoug, PhD, Paola Neri, MD, PhD, Jiri Slaby, MD, Jacquelyn Babich, Justin Simms, Kathy Gratton, Li Ren, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 3165.
https://doi.org/10.1182/blood.V122.21.3165.3165
Published: 2013
Journal Articles

RNA-Sequencing Of Paired Pre-Treatment and Relapse Samples Reveals Differentially Expressed Genes Associated With Lenalidomide Resistance In Multiple Myeloma

Paola Neri, MD, PhD, Kathy Gratton, Li Ren, PhD, Jiri Slaby, MD, Ines Tagoug, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2013) 122 (21): 530.
https://doi.org/10.1182/blood.V122.21.530.530
Published: 2013
Journal Articles

Role of Mir-30e in Multiple Myeloma Cells Resistance to Lenalidomide and Bortezomib

Paola Neri, MD, PhD, Kathy Gratton, Li Ren, PhD, Jordan Johnson, Jiri Slaby, MD, Peter Duggan, MD, Douglas A. Stewart, MD, FRCP, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 323.
https://doi.org/10.1182/blood.V120.21.323.323
Published: 2012
Journal Articles

Phase I Study of the PARP1-2 Inhibitor Veliparib in Combination with Bortezomib in Patients with Relapsed or Refractory Multiple Myeloma

Paola Neri, MD, PhD, Peter Duggan, MD, FRCPC, Kathy Gratton, Li Ren, PhD, Jordan Johnson, Jiri Slaby, MD, Douglas A. Stewart, MD, FRCP, Jonathan J Keats, PhD, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 1862.
https://doi.org/10.1182/blood.V120.21.1862.1862
Published: 2012
Journal Articles

High Cereblon Protein Expression Correlates with Improved Response and Survival in Myeloma Patients Treated with Lenalidomide

Alexander Klimowicz, PhD, Paola Neri, MD, PhD, Andrew Belch, MD, Michelle Dean, Li Ren, PhD, Kathy Gratton, Jiri Slaby, MD, Jordan Johnson, Peter Duggan, MD, FRCPC, Douglas A. Stewart, MD, FRCPC, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 931.
https://doi.org/10.1182/blood.V120.21.931.931
Published: 2012
Journal Articles

Lenalidomide Suppresses 5′-Cap-Independent C-MYC Translation in Multiple Myeloma Cells

Jiri Slaby, MD, Jordan Johnson, Paola Neri, MD, PhD, K Gratton, Li Ren, PhD, Douglas A. Stewart, MD, FRCP, Peter Duggan, MD, FRCPC, Nizar J. Bahlis, MD
Journal: Blood
Blood (2012) 120 (21): 3943.
https://doi.org/10.1182/blood.V120.21.3943.3943
Published: 2012
Journal Articles

A “Single” Dose of G-CSF after Autologous Stem Cell Transplantation in Patients with Malignant Lymphoma - Third Interim Analysis of Multicentre Randomized Trial Comparing Standard Schedule with Delayed Application and Placebo.

Edgar Faber, Robert Pytlik, Marek Trneny, Jiri Slaby, Tomas Kozak, Ludek Raida, Tomas Papajik, Eva Zikesova, Jana Zapletalova, Ivana Maresova, Michaela Hamouzova, Karel Indrak
Journal: Blood
Blood (2004) 104 (11): 2925.
https://doi.org/10.1182/blood.V104.11.2925.2925
Published: 2004