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Journal Articles

IL-6 Deficiency Reverses Leukemic Transformation in an MDS Mouse Model

Yang Mei, PhD, Yijie Liu, PhD, Xu Han, PhD, Jing Yang, PhD, Peng Ji, MDPhD

Blood (2020) 136 (Supplement 1): 36.

https://doi.org/10.1182/blood-2020-137026

Published: 2020

Journal Articles

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Shaowei Qiu, MD, Chengcheng Yan, MD, Andrew J Paterson, PhD, Hui Li, BS, Nick Anderson, BS, Ajay Abraham, PhD, Jianbo He, MD, Mansi Shah, PhD, Puneet Agarwal, Jing Yang, PhD, Min Xie, MD, Rui Lu, PhD, Rob S. Welner, PhD, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 2548.

https://doi.org/10.1182/blood-2019-124948

Published: 2019

Journal Articles

An Open Label Study of Alpn-101, a First-in-Class Dual CD28/ICOS Antagonist, in Subjects with Steroid-Resistant or Steroid-Refractory Acute Graft Versus Host Disease (aGVHD)

Jing Yang, PhD, Jan L. Hillson, MD, Kristi L. Manjarrez, Jennifer R. Wiley, DRSc, Gary D. Means, PhD, Stacey R. Dillon, PhD, Stanford L. Peng, MD,PhD

Blood (2019) 134 (Supplement_1): 372.

https://doi.org/10.1182/blood-2019-126034

Published: 2019

Journal Articles

Universal SLAMF7-Specific CAR T-Cells As Treatment for Multiple Myeloma

Rohit Mathur, PhD, Zheng Zhang, Jin He, Roman Galetto, PhD, Agnès Gouble, PhD, Isabelle Chion-Sotinel, Stéphanie Filipe, PhD, Annabelle Gariboldi, Tanooha Veeramachaneni, Elisabet E. Manasanch, MD, Sheeba K. Thomas, MD, Hans C. Lee, MD, Krina K. Patel, MDMSc, Donna M. Weber, MD, R. Eric Davis, MD, Robert J. Orlowski, MD PhD, Julianne Smith, PhD, Jing Yang, PhD, Sattva S. Neelapu, MD

Blood (2017) 130 (Supplement 1): 502.

https://doi.org/10.1182/blood.V130.Suppl_1.502.502

Published: 2017

Journal Articles

C-Reactive Protein Promotes Bone Destruction in Human Myeloma By Stimulating Myeloma Cell Production of Osteolytic Cytokines Via the CD32/FcγRII-p38MAPK-Twist Axis

Jing Yang, PhD, Zhiqiang Liu, PhD, Huan Liu, PhD, Jin He, Jianling Yang, PhD, Pei Lin, MDDM,MDC, Qiang WANG, PhD, Juan Du, PhD MD, Wencai Ma, Richard E Davis, BSPharm, MS, Robert Z. Orlowski, MD PhD, Jian Hou, MD, Qing Yi, MD PhD

Blood (2017) 130 (Supplement 1): 3043.

https://doi.org/10.1182/blood.V130.Suppl_1.3043.3043

Published: 2017

Journal Articles

B-Cell Maturation Antigen (BCMA)-Specific, Centyrin TM -Based, PiggyBac TM -Transposed CAR-T Memory Stem Cells Are Effective Against p53 -/- and Patient-Derived Multiple Myeloma Tumors

Blood (2017) 130 (Supplement 1): 3068.

https://doi.org/10.1182/blood.V130.Suppl_1.3068.3068

Published: 2017

Journal Articles

ONC201 Overcomes Chemotherapy Resistance By Upregulation of Bim in Multiple Myeloma

Yong-sheng Tu, PhD, Jin He, M.S., Huan Liu, PhD, Richard Eric Davis, MD, Robert Z. Orlowski, MD, PhD, Joshua E Allen, PhD, Jing Yang, PhD

Blood (2016) 128 (22): 4476.

https://doi.org/10.1182/blood.V128.22.4476.4476

Published: 2016

Journal Articles

Inhibition of USP10 Induces Degradation of Oncogenic FLT3: A Novel Approach to Therapy of Leukemia

Sara Buhrlage, PhD, Ellen Weisberg, MD, Nathan Schauer, Jing Yang, PhD, Ilaria Lamberto, PhD, Laura Doherty, Atsushi Nonami, MDPhD, Amanda L. Christie, BS, David M. Weinstock, MD, Richard M. Stone, MD, Nathanael Gray, PhD, James D Griffin, MD

Blood (2016) 128 (22): 524.

https://doi.org/10.1182/blood.V128.22.524.524

Published: 2016

Journal Articles

Thymidine Phosphorylase Exerts Complex Effects on Bone Resorption and Formation in Myeloma

Huan Liu, PhD, Zhiqiang Liu, PhD, Juan Du, MD, Jin He, M.S., Pei Lin, MD, Amini Behrang, MD, Michael W Starbuck, M.S., Nora M Novane, MD, Jatin J. Shah, MD, Richard Eric Davis, MD, Jian Hou, MD, Robert Gagel, MD, Jing Yang, PhD

Blood (2016) 128 (22): 1135.

https://doi.org/10.1182/blood.V128.22.1135.1135

Published: 2016

Journal Articles

Resistin Induces Multidrug Resistance in Myeloma By Inhibiting Cell Death and Upregulating ABC Transporter Expression

Jianan Pang, MD, Qiaofa Shi, Zhiqiang Liu, PhD, Jin He, M.S., Huan Liu, PhD, Pei Lin, MD, Robert Z. Orlowski, PhD, MD, Jiuwei Cui, Jing Yang, PhD

Blood (2016) 128 (22): 5656.

https://doi.org/10.1182/blood.V128.22.5656.5656

Published: 2016

Journal Articles

RNA Polymerase I Inhibition with CX-5461 As a Novel Strategy to Target MYC in Multiple Myeloma

Hans Lee, MD, Hua Wang, PhD, Heather Lin, M.S., Veera Baladandayuthapani, PhD, Jin He, Richard Julian Jones, PhD, Isere Kuiatse, PhD, Dongmin Gu, MD, PhD, Zhiqiang Wang, PhD, Sean O'Brien, PhD, Jonathan J Keats, PhD, Jing Yang, PhD, Richard Eric Davis, MD, Robert Z. Orlowski, PhD, MD

Blood (2015) 126 (23): 3010.

https://doi.org/10.1182/blood.V126.23.3010.3010

Published: 2015

Journal Articles

Myeloma Cells Switch Osteoblastogenesis to Adipogenesis and Suppress Bone Formation

Jing Yang, PhD, Zhiqiang Liu, PhD, Huan Liu, Jin He, Pei Lin, MD, Robert Z Orlowski, MD, PhD, Larry W Kwak, MD PhD, Qiang Tong, PhD, Robert Gagel, MD

Blood (2014) 124 (21): 3386.

https://doi.org/10.1182/blood.V124.21.3386.3386

Published: 2014

Journal Articles

Studies of the Proteasome Inhibitor Sensitivity Modulator Tight Junction Protein 1 Highlight a Role for Signaling through the Epidermal Growth Factor Receptor in Determining Proteasome Capacity

Blood (2014) 124 (21): 3414.

https://doi.org/10.1182/blood.V124.21.3414.3414

Published: 2014

Journal Articles

Anti-β2 Microglobulin Monoclonal Antibodies Overcome Bortezomib-Induced Drug Resistance In Multiple Myeloma By Inhibition Of Autophagy

Mingjun Zhang, PhD, Jin He, Yong Lu, PhD, Yuhuan Zheng, PhD, Bangxing Hong, MD, PhD, Haiyan Li, MD, PhD, Zhiqiang Liu, PhD, Jingda Xu, PhD, Huan Liu, Jianfei Qian, PhD, Qing Yi, MD, PhD, Jing Yang, PhD

Blood (2013) 122 (21): 929.

https://doi.org/10.1182/blood.V122.21.929.929

Published: 2013

Journal Articles

Activation Of Autophagy By Bone Marrow Adipocytes Protects Myeloma Cells From Chemotherapy-Induced Apoptosis

Jing Yang, PhD, Jingda Xu, PhD, Zhiqiang Liu, PhD, Jin He, Huan Liu, Pei Lin, MD, Robert Z. Orlowski, M.D., Ph.D, Larry W. Kwak, MD, PhD, Qing Yi, MD, PhD

Blood (2013) 122 (21): 1915.

https://doi.org/10.1182/blood.V122.21.1915.1915

Published: 2013

Journal Articles

Regulation Of DKK-1 Expression By p38 MAPK Signaling Via CREB Myeloma Cells

Jing Yang, PhD, Yuping Zhong, MD, Jin He, Zhiqiang Liu, PhD, Huan Liu, Pei Lin, MD, Robert Z. Orlowski, M.D., Ph.D., Larry W. Kwak, MD, PhD

Blood (2013) 122 (21): 1917.

https://doi.org/10.1182/blood.V122.21.1917.1917

Published: 2013

Journal Articles

P38 MAPK Activity in Myeloma Cells Regulates Osteoclast and Osteoblast Activity and Induces Bone Destruction in Vivo

Jin He, PhD, Zhiqiang Liu, PhD, Yuhuan Zheng, PhD, Jianfei Qian, PhD, Haiyan Li, MD, PhD, Yong Lu, PhD, Jingda Xu, PhD, Bangxing Hong, PhD, Mingjun Zhang, PhD, Pei Lin, MD, Zhen Cai, Robert Z. Orlowski, M.D., Ph.D., Larry W Kwak, MD, PhD, Qing Yi, MD, PhD, Jing Yang, PhD

Blood (2012) 120 (21): 566.

https://doi.org/10.1182/blood.V120.21.566.566

Published: 2012

Journal Articles

Myeloma Cells Exhibit Inhibitory Effect On Osteoclastogenesis

Zhiqiang Liu, PhD, Yuhuan Zheng, PhD, Haiyan Li, MD, PhD, Jingda Xu, PhD, Jin He, Eryong Huang, Yong Lu, PhD, Jungsun Park, Bangxing Hong, PhD, Mingjun Zhang, PhD, Jianfei Qian, PhD, Pei Lin, MD, Larry W. Kwak, MD, PhD, Qing Yi, MD, PhD, Jing Yang, PhD

Blood (2012) 120 (21): 439.

https://doi.org/10.1182/blood.V120.21.439.439

Published: 2012

Journal Articles

Reciprocal Interaction Between Osteoclasts and T Cells: Osteoclasts Inhibit T Cell Proliferation by IDO Produced in Response to T Cell-Derived IFN-γ and CD40 Ligand

Haiyan Li, MD, PhD, Yong Lu, PhD, Sungyoul Hong, PhD, Jianfei Qian, PhD, Zhiqiang Liu, Yuhuan Zheng, PhD, Yongsheng Lan, Jin He, Jing Yang, PhD, Qing Yi, MD, PhD

Blood (2011) 118 (21): 694.

https://doi.org/10.1182/blood.V118.21.694.694

Published: 2011

Journal Articles

P/E Selectins and Their Ligand PSGL-1 Are Crucial for Macrophage-Mediated Multiple Myeloma Chemoresistance

Yuhuan Zheng, Jing Yang, PhD, Jianfei Qian, Shino Hanabuchi, Zhiqiang Liu, Yong Lu, PhD, Jin He, Haiyan Li, MD, PhD, Jatin J Shah, MD, Yongsheng Lan, Qing Yi, MD, PhD

Blood (2011) 118 (21): 130.

https://doi.org/10.1182/blood.V118.21.130.130

Published: 2011

NARROW

IL-6 Deficiency Reverses Leukemic Transformation in an MDS Mouse Model

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

An Open Label Study of Alpn-101, a First-in-Class Dual CD28/ICOS Antagonist, in Subjects with Steroid-Resistant or Steroid-Refractory Acute Graft Versus Host Disease (aGVHD)

Universal SLAMF7-Specific CAR T-Cells As Treatment for Multiple Myeloma

C-Reactive Protein Promotes Bone Destruction in Human Myeloma By Stimulating Myeloma Cell Production of Osteolytic Cytokines Via the CD32/FcγRII-p38MAPK-Twist Axis

B-Cell Maturation Antigen (BCMA)-Specific, Centyrin TM -Based, PiggyBac TM -Transposed CAR-T Memory Stem Cells Are Effective Against p53 -/- and Patient-Derived Multiple Myeloma Tumors

ONC201 Overcomes Chemotherapy Resistance By Upregulation of Bim in Multiple Myeloma

Inhibition of USP10 Induces Degradation of Oncogenic FLT3: A Novel Approach to Therapy of Leukemia

Thymidine Phosphorylase Exerts Complex Effects on Bone Resorption and Formation in Myeloma

Resistin Induces Multidrug Resistance in Myeloma By Inhibiting Cell Death and Upregulating ABC Transporter Expression

RNA Polymerase I Inhibition with CX-5461 As a Novel Strategy to Target MYC in Multiple Myeloma

Myeloma Cells Switch Osteoblastogenesis to Adipogenesis and Suppress Bone Formation

Studies of the Proteasome Inhibitor Sensitivity Modulator Tight Junction Protein 1 Highlight a Role for Signaling through the Epidermal Growth Factor Receptor in Determining Proteasome Capacity

Anti-β2 Microglobulin Monoclonal Antibodies Overcome Bortezomib-Induced Drug Resistance In Multiple Myeloma By Inhibition Of Autophagy

Activation Of Autophagy By Bone Marrow Adipocytes Protects Myeloma Cells From Chemotherapy-Induced Apoptosis

Regulation Of DKK-1 Expression By p38 MAPK Signaling Via CREB Myeloma Cells

P38 MAPK Activity in Myeloma Cells Regulates Osteoclast and Osteoblast Activity and Induces Bone Destruction in Vivo

Myeloma Cells Exhibit Inhibitory Effect On Osteoclastogenesis

Reciprocal Interaction Between Osteoclasts and T Cells: Osteoclasts Inhibit T Cell Proliferation by IDO Produced in Response to T Cell-Derived IFN-γ and CD40 Ligand

P/E Selectins and Their Ligand PSGL-1 Are Crucial for Macrophage-Mediated Multiple Myeloma Chemoresistance

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American Society of Hematology

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American Society of Hematology

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