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Journal Articles

Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia

Blood (2020) 136 (Supplement_2): LBA-3.

https://doi.org/10.1182/blood-2020-143881

Published: 2020

Journal Articles

Genomic Analysis of Congenital Myeloid Sarcoma Identifies Significant Bone Marrow Involvement in the Absence of Morphologic Blasts

Jennifer Kamens, MD, Jinjun Dang, PhD, Sarah Aldridge, MSN, Jing Ma, PhD, Yuanyuan Wang, PhD, Gang Wu, PhD, Vasiliki Leventaki, MD, Susana C. Raimondi, PhD, Joy Nakitandwe, PhD, Alberto Pappo, MD, Tanja Gruber, MDPhD

Blood (2020) 136 (Supplement 1): 41.

https://doi.org/10.1182/blood-2020-142168

Published: 2020

Journal Articles

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

Jason R Schwartz, MD PhD, Jing Ma, PhD, Michael P Walsh, PhD, Xiaolong Chen, PhD, Tamara Lamprecht, BS, Jennifer Kamens, MD, Scott Newman, PhD, Jinghui Zhang, PhD, Tanja A. Gruber, MD PhD, Xiaotu Ma, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): 1394.

https://doi.org/10.1182/blood-2019-128665

Published: 2019

Journal Articles

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Blood (2019) 134 (Supplement_1): 918.

https://doi.org/10.1182/blood-2019-127411

Published: 2019

Journal Articles

The Mutational Profile of Pediatric Therapy-Related Myeloid Neoplasms

Jason R Schwartz, MD PhD, Michael P Walsh, PhD, Jing Ma, PhD, Tamara Lamprecht, B.S., Raul C Ribeiro, MD, Jeffery M. Klco, MD PhD

Blood (2018) 132 (Supplement 1): 2775.

https://doi.org/10.1182/blood-2018-99-118995

Published: 2018

Journal Articles

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Mattias Pilheden, MSc, Axel Hyrenius Wittsten, MSc, Veronica Gonzalez-Pena, PhD, Helena Sturesson, PhD, Michael P Walsh, PhD, Guangchun Song, PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Lausen, MD PhD, Anders Castor, MD PhD, Jinghui Zhang, PhD, James R. Downing, MD, Jing Ma, PhD, Charles Gawad, MD PhD, Anna K. Andersson, PhD

Blood (2017) 130 (Supplement 1): 2709.

https://doi.org/10.1182/blood.V130.Suppl_1.2709.2709

Published: 2017

Journal Articles

Activating Mutations Are Potent Pro-Leukemic Mediators in Murine MLL-MLLT3 Leukemia That Cause Distinct Transcriptional Profiles

Axel Hyrenius-Wittsten, MSc, Helena Sturesson, PhD, Michael P. Walsh, PhD, Jenny Hansson, PhD, Julhash U. Kazi, PhD, Mattias Pilheden, MSc, Stephanie Nance, Pankaj Gupta, Guangchun Song, PhD, Jinghui Zhang, PhD, Jing Ma, PhD, Tanja A. Gruber, MD PhD, James R. Downing, MD PhD, Anna K. Andersson, PhD

Blood (2016) 128 (22): 3918.

https://doi.org/10.1182/blood.V128.22.3918.3918

Published: 2016

Journal Articles

The Genomic Landscape of Pediatric Myelodysplastic Syndromes

Jason R. Schwartz, MD PhD, Michael P. Walsh, PhD, Jing Ma, PhD, Tamara Lamprecht, B.S., Shuoguo Wang, PhD, Gang Wu, PhD, John Easton, PhD, Raul C. Ribeiro, MD, Jeffery M. Klco, MD PhD

Blood (2016) 128 (22): 956.

https://doi.org/10.1182/blood.V128.22.956.956

Published: 2016

Journal Articles

Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia

Blood (2015) 126 (23): 692.

https://doi.org/10.1182/blood.V126.23.692.692

Published: 2015

Journal Articles

Expression of an Oncogenic ERG isoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia

Jinghui Zhang, PhD, Kelly McCastlain, Chunxu Qu, PhD, Gang Wu, PhD, Michael Edmonson, PhD, Yongjin Li, PhD, Lei Wei, PhD, Debbie Payne-Turner, BS, Hiroki Yoshihara, MDPhD, Michelle L. Churchman, PhD, Esmé Waanders, PhD, Panagiotis Ntziachristos, PhD, Iannis Aifantis, PhD, Kathryn G. Roberts, Jing Ma, PhD, Guangchun Song, PhD, John Easton, PhD, Heather L. Mulder, BS, Xiang Chen, PhD, Michael Rusch, BA, Kristy Boggs, PhD, Bhavin Vadodaria, BS, James Dalton, BS, Marcus L Valentine, PhD, Li Ding, PhD, Charles Lu, PhD, Robert S. Fulton, PhD, Lucinda Fulton, PhD, Yashodan Tabib, PhD, Kerri Ochoa, Meenakshi Devidas, PhD, Deqing Pei, Cheng Cheng, PhD, William E. Evans, PharmD, Ching-Hon Pui, MD, Sima Jeha, MD, Richard C. Harvey, PhD, I-Ming L Chen, DVM, MS, Cheryl L. Willman, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD, Jessica Kohlschmidt, PhD BS, MS, Krzysztof Mrozek, MD PhD, Elisabeth Paietta, PhD, Martin S. Tallman, MD, Wendy Stock, MD, Peter M. Voorhees, MD, Janis Racevskis, MD, Jacob M. Rowe, MD, Selina Luger, MD, Steven M. Kornblau, MD, Sheila A Shurtleff, PhD, Susana C. Raimondi, PhD, Elaine R Mardis, PhD, Richard K Wilson, PhD, Stephen P Hunger, MD, Mignon L. Loh, MD, James R. Downing, MD, Charles G. Mullighan

Blood (2015) 126 (23): 693.

https://doi.org/10.1182/blood.V126.23.693.693

Published: 2015

Journal Articles

Next Generation Sequencing Identifies a Novel Subset of Non-Down Syndrome Acute Megakaryoblastic Leukemia Characterized By Chimeric Transcripts Involving HOX Cluster Genes

Blood (2015) 126 (23): 171.

https://doi.org/10.1182/blood.V126.23.171.171

Published: 2015

Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Benjamin Heath Durham, MD BS, Eli L. Diamond, MD, Julien Haroche, MD PhD, Zhan Yao, PhD, Jing Ma, PhD, Sameer A. Parikh, MD, John Choi, Eunhee Kim, PhD, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, MD, Patrick Campbell, MD PhD, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Aminova Olga, Adriana Heguy, Paul Zappile, Joy Nakitandwe, BSc,MSc,PhD, James Dalton, BS, David W Ellison, MD, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, MD PhD, Phil Stephens, PhD, Vincent A. Miller, MD, Jeffrey Ross, Siraj Ali, Sebastien Héritier, Jean Donadieu, MD PhD, David Solit, MD, David M. Hyman, Jose Baselga, MD PhD, Filip Janku, MDPhD, Barry S. Taylor, PhD, Christopher Y. Park, MD, PhD, Ahmet Dogan, MD PhD, Zahir Amoura, Jean-Francois Emile, Raajit K. Rampal, MD, PhD, Neal Rosen, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab

Blood (2015) 126 (23): 481.

https://doi.org/10.1182/blood.V126.23.481.481

Published: 2015

Journal Articles

Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes

Jasmine C. Wong, PhD, Kelley Weinfurtner, BA, Pilar Alzamora, Scott C. Kogan, MD, Michael R. Burgess, MD PhD, Yan Zhang, PhD, Joy Nakitandwe, PhD, Jing Ma, PhD, Jinjun Cheng, MB, MS, Shann-Ching Chen, PhD, Johanna Flach, Damien Reynaud, PhD, Emmanuelle Passegue, PhD, James R Downing, MD, Kevin Shannon, MD

Blood (2014) 124 (21): 3247.

https://doi.org/10.1182/blood.V124.21.3247.3247

Published: 2014

Journal Articles

Targeted Inhibition of the MLL Transcriptional Complex By Proteosome Inhibitors Elicits a High Response Rate in Relapsed/Refractory MLL Rearranged Leukemia

Cary Koss, BS, Stephanie Nance, PhD, Michele Connelly, MS, Jing Ma, PhD, Anang Shelat, PhD, Anitria Cotton, BS, Qi An, MS, Cheng Cheng, PhD, Monika L. Metzger, MD MS, Sima Jeha, MD, Jeffrey E Rubnitz, MD PhD, James R Downing, MD, R. Kiplin Guy, PhD, Tanja A Gruber, MD PhD

Blood (2014) 124 (21): 972.

https://doi.org/10.1182/blood.V124.21.972.972

Published: 2014

Journal Articles

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Benjamin Durham, MD, Jing Ma, PhD, Eunhee Kim, PhD, John K. Choi, MD, Patrick Campbell, MD PhD, Juvianee Estrada-Veras, MD, Michael P Walsh, PhD, Mario E Lacouture, MD, Young Rock Chung, MS, Joy Nakitandwe, PhD, Eli Diamond, David M. Hyman, MD, Raajit K. Rampal, MD PhD, Minal Patel, Christopher Y. Park, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab, MD

Blood (2014) 124 (21): 1887.

https://doi.org/10.1182/blood.V124.21.1887.1887

Published: 2014

Journal Articles

Novel AMKL Chimeric Transcription Factors Are Potent Inducers of Leukemia with Unique Mechanisms of Leukemogenesis

Jinjun Dang, PhD, Stephanie Nance, PhD, Amanda Larson Gedman, PhD, Jinjun Cheng, MD PhD, Jing Ma, PhD, Michael P Walsh, PhD, Cary Koss, BS, Peter Vogel, DVM, PhD, James R Downing, MD, Tanja A Gruber, MD PhD

Blood (2014) 124 (21): 477.

https://doi.org/10.1182/blood.V124.21.477.477

Published: 2014

Journal Articles

High Content Screening Identifies Synthetic Lethality Of Retinoid Receptor Agonists In IKZF1 -Mutated BCR-ABL1 positive Acute Lymphoblastic Leukemia

Michelle Churchman, Ph.D., Jonathan Low, Ph.D., Debbie Payne-Turner, Shann-Ching Chen, PhD, Jing Ma, PhD, Mark J. Althoff, Faiyaz Notta, PhD, John E. Dick, PhD, Laura Janke, DVM, PhD, Rodney Kiplin Guy, Ph.D, Taosheng Chen, Ph.D., Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA

Blood (2013) 122 (21): 172.

https://doi.org/10.1182/blood.V122.21.172.172

Published: 2013

Journal Articles

Integrated Genomic and Mutational Profiling Of Adolescent and Young Adult ALL Identifies a High Frequency Of BCR-ABL1 -Like ALL with Very Poor Outcome

Blood (2013) 122 (21): 825.

https://doi.org/10.1182/blood.V122.21.825.825

Published: 2013

Journal Articles

Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic Leukemia (ALL) Patients With a Philadelphia Chromosome-Like (“ Ph-like ” or “ BCR-ABL1-Like ”) Signature For Therapeutic Targeting and Clinical Intervention

Blood (2013) 122 (21): 826.

https://doi.org/10.1182/blood.V122.21.826.826

Published: 2013

Journal Articles

Genomic- and Transcriptomic Profiling Of Acute Lymphoblastic Leukemia With Dicentric Chromosomes

Linda Holmfeldt, PhD, Paolo Vignali, Debbie Payne-Turner, Jing Ma, PhD, Guangchun Song, Pankaj Gupta, Michael Rusch, BA, Jinghui Zhang, PhD, Nyla A. Heerema, PhD, Susana C Raimondi, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA

Blood (2013) 122 (21): 234.

https://doi.org/10.1182/blood.V122.21.234.234

Published: 2013

NARROW

Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia

Genomic Analysis of Congenital Myeloid Sarcoma Identifies Significant Bone Marrow Involvement in the Absence of Morphologic Blasts

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

The Mutational Profile of Pediatric Therapy-Related Myeloid Neoplasms

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Activating Mutations Are Potent Pro-Leukemic Mediators in Murine MLL-MLLT3 Leukemia That Cause Distinct Transcriptional Profiles

The Genomic Landscape of Pediatric Myelodysplastic Syndromes

Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia

Expression of an Oncogenic ERG isoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia

Next Generation Sequencing Identifies a Novel Subset of Non-Down Syndrome Acute Megakaryoblastic Leukemia Characterized By Chimeric Transcripts Involving HOX Cluster Genes

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes

Targeted Inhibition of the MLL Transcriptional Complex By Proteosome Inhibitors Elicits a High Response Rate in Relapsed/Refractory MLL Rearranged Leukemia

Unraveling the Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms through Whole Exome Sequencing

Novel AMKL Chimeric Transcription Factors Are Potent Inducers of Leukemia with Unique Mechanisms of Leukemogenesis

High Content Screening Identifies Synthetic Lethality Of Retinoid Receptor Agonists In IKZF1 -Mutated BCR-ABL1 positive Acute Lymphoblastic Leukemia

Integrated Genomic and Mutational Profiling Of Adolescent and Young Adult ALL Identifies a High Frequency Of BCR-ABL1 -Like ALL with Very Poor Outcome

Genomic- and Transcriptomic Profiling Of Acute Lymphoblastic Leukemia With Dicentric Chromosomes

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American Society of Hematology

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