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Jing Chen, PhD
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Journal Articles

The Genetics and Clinical Characteristics of Children Morphologically Diagnosed As Acute Promyelocytic Leukaemia

Jie Zhao, PhD, Liang Jian-Wei, Shuhong Shen, MD PhD, Jing Chen, PhD, Hui-Liang Xue, Ben-Shang LI, MD, Jing-Yan Tang
Journal: Blood
Blood (2018) 132 (Supplement 1): 2801.
https://doi.org/10.1182/blood-2018-99-112401
Published: 2018
Journal Articles

A Novel Megakaryocyte-Based Screening System Identifies Compounds That Promote Megakaryocyte Maturation and Platelet Production in Vitro

Si Jing Chen, PhD, Hideya Seo, Akitsu Hotta, Yohei Nishi, Akira Ohta, Koji Eto
Journal: Blood
Blood (2017) 130 (Supplement 1): 2329.
https://doi.org/10.1182/blood.V130.Suppl_1.2329.2329
Published: 2017
Journal Articles

Phosphoglycerate Mutase 1 Promotes Leukemia Metabolism by Coordinating Glycolysis and Biosynthesis, and Represnts a Therapuetic Target in Leukemia Treatment

Taro Hitosugi, PhD, Lu Zhou, PhD, Jun Fan, PhD, Martha Arellano, MD, Hanna J. Khoury, MD, Benjamin H. Lee, MD, PhD, Titus Boggon, PhD, Sumin Kang, PhD, Chuan He, Jing Chen, PhD
Journal: Blood
Blood (2012) 120 (21): 860.
https://doi.org/10.1182/blood.V120.21.860.860
Published: 2012
Journal Articles

Leukemogenic Tyrosine Kinases Inhibit PKM2 to Promote the Warburg Effect and Tumor Growth

Taro Hitosugi, PhD, Sumin Kang, PhD, Matthew Vander Heiden, MD/PhD, Tea-wook Chung, PhD, Shannon Elf, Katherine Lythgoe, Shaozhong Dong, PhD, Sagar Lonial, MD, Xu Wang, PhD, Georgia Chen, PhD, Jianxin Xie, PhD, Ting-Lei Gu, PhD, Roberto Polakiewicz, PhD, Johannes L. Roesel, PhD, Titus Boggon, PhD, Fadlo Khuri, MD, D. Gary Gilliland, MD, PhD, Lewis Cantley, PhD, Jonathan L. Kaufman, MD, Jing Chen, PhD
Journal: Blood
Blood (2010) 116 (21): 3142.
https://doi.org/10.1182/blood.V116.21.3142.3142
Published: 2010
Journal Articles

Targeting 14-3-3 Sensitizes Native and Mutant BCR-ABL to Inhibition with U0126, Rapamycin and Bcl-2 Inhibitor GX15-070.

Shaozhong Dong, PhD, Sumin Kang, PhD, Sagar Lonial, MD, Hanna Jean Khoury, MD, Jean Viallet, PhD, Jing Chen, PhD
Journal: Blood
Blood (2007) 110 (11): 2920.
https://doi.org/10.1182/blood.V110.11.2920.2920
Published: 2007
Journal Articles

p90RSK2 as a Therapeutic Target in Treatment of FGFR3-Expressing t(4;14) Multiple Myeloma.

Sumin Kang, PhD, Shaozhong Dong, PhD, Tinglei Gu, PhD, Ailan Guo, PhD, Michael S. Cohen, PhD, Sagar Lonial, MD, PhD, Petet Leif Bergsagel, MD, PhD, Jack Taunton, PhD, Roberto D. Polakiewicz, PhD, Jing Chen, PhD
Journal: Blood
Blood (2007) 110 (11): 253.
https://doi.org/10.1182/blood.V110.11.253.253
Published: 2007
Journal Articles

14-3-3 Integrates Pro-Survival Signals in Hematopoietic Cells Transformed by Diverse Leukemogenic Tyrosine Kinases, and Represents a Common Target.

Shaozhong Dong, PhD, Sumin Kang, PhD, Ting-lei Gu, PhD, Sean Kardar, Sagar Lonial, MD, H. Jean Khoury, MD, Fadlo Khuri, MD, Haian Fu, PhD, Jing Chen, PhD
Journal: Blood
Blood (2006) 108 (11): 1138.
https://doi.org/10.1182/blood.V108.11.1138.1138
Published: 2006
Journal Articles

FGFR3 Activates RSK2 To Mediate Hematopoietic Transformation through Both Tyrosine Phosphorylation of RSK2 and Activation of the MEK/ERK Pathway.

Sumin Kang, PhD, Shaozhong Dong, PhD, Ting-lei Gu, PhD, Michael S. Cohen, Sagar Lonial, MD, H. Jean Khoury, PhD, D. Gary Gilliland, MD, PhD, Jack Taunton, PhD, Roberto D. Polakiewicz, PhD, Jing Chen, PhD
Journal: Blood
Blood (2006) 108 (11): 514.
https://doi.org/10.1182/blood.V108.11.514.514
Published: 2006
Journal Articles

Juxtamembrane Domain Truncation Is Sufficient for Activation of the FIP1L1-PDGFRα and ETV6-PDGFRβ Fusion Kinases.

Elizabeth H. Stover, BA, Jing Chen, PhD, Cedric Folens, Benjamin H. Lee, MD, PhD, Nicole Mentens, Peter Marynen, PhD, D. Gary Gilliland, PhD, MD, Jan Cools, PhD
Journal: Blood
Blood (2005) 106 (11): 3511.
https://doi.org/10.1182/blood.V106.11.3511.3511
Published: 2005