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Journal Articles

Platelet-Derived Serotonin Stimulates TPO Production from Bone Marrow Mesenchymal Stromal Cells but Not Hepatocytes

En Yu Liang, Jie Yu Ye, Li Xia Zhou, Chunfu Li, MD, Beng H Chong, PhD, Mo Yang, PhD
Journal: Blood
Blood (2015) 126 (23): 4773.
https://doi.org/10.1182/blood.V126.23.4773.4773
Published: 2015
Journal Articles

Melatonin Protects Against Apoptosis of Megakaryocytes Via Its Receptors and Activation of PI3k/Akt Pathway

Su-yi Li, MD, Min Zhou, MD, Jie-yu Ye, MDPhD, Qi-zhou Lian, MDPhD, Fan-yi Meng, MD, Mo Yang, MDPhD
Journal: Blood
Blood (2014) 124 (21): 4201.
https://doi.org/10.1182/blood.V124.21.4201.4201
Published: 2014
Journal Articles

Angelica Polysaccharide and TPO Have a Protective Effect On Hcmv-Induced Apoptosis In Megakaryocytes

Mo Yang, MD, PhD, Jian Liang Chen, Jie yu Ye, MD, PhD, Su yi Li, En yu Liang, Beng Chong, MBBS FRCPA FRACP PhD
Journal: Blood
Blood (2013) 122 (21): 3553.
https://doi.org/10.1182/blood.V122.21.3553.3553
Published: 2013
Journal Articles

Serotonin and Its Metabolism Enhances Megakaryopoiesis and Proplatelet Formation

Jie yu Ye, MD, PhD, Fan yi Meng, MD, Qianli Jiang, Su yi Li, En yu Liang, Beng Chong, MBBS FRCPA FRACP PhD, Mo Yang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4753.
https://doi.org/10.1182/blood.V122.21.4753.4753
Published: 2013
Journal Articles

Serotonin regulates TPO production from bone marrow mesenchymal stromal cells

Jie yu Ye, MD, PhD, En yu Liang, Su yi Li, Godfrey ChiFung Chan, MD, Mo Yang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3690.
https://doi.org/10.1182/blood.V122.21.3690.3690
Published: 2013
Journal Articles

Tanshinone IIA has anti-platelet effect and induces apoptosis in megakaryocytes via TNFR and Caspases

Mo Yang, MD, PhD, Fu qun Wu, Min Zhou, Jie yu Ye, MD, PhD, Xiao jing Li, MD, Beng Chong, MBBS FRCPA FRACP PhD, Chang Liu, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3635.
https://doi.org/10.1182/blood.V122.21.3635.3635
Published: 2013
Journal Articles

TPO plus Tanshinone IIA has neural protective effect and this effect may be mediated via its receptor c-mpl and PI3K/Akt signaling

Mo Yang, MD, PhD, Jie yu Ye, MD, PhD, Su yi Li, En yu Liang, Fan yi Meng, MD, Qizhou Lian, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5565.
https://doi.org/10.1182/blood.V122.21.5565.5565
Published: 2013
Journal Articles

Imatinib mesylate has an inhibitory effect on hematopoiesis in a mice model

Jie yu Ye, MD, PhD, Su yi Li, En yu Liang, Fan yi Meng, MD, Beng Chong, MBBS FRCPA FRACP PhD, Mo Yang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5568.
https://doi.org/10.1182/blood.V122.21.5568.5568
Published: 2013
Journal Articles

TPO exerts a protective effect on iron-overload induces apoptosis in cardiomyocytes via mitochondrial pathways

Mo Yang, MD, PhD, Shing Chan, Jie yu Ye, MD, PhD, Godfrey ChiFung Chan, MD
Journal: Blood
Blood (2013) 122 (21): 4668.
https://doi.org/10.1182/blood.V122.21.4668.4668
Published: 2013
Journal Articles

The Molecular Mechanisms of Serotonin in the Regulation of Megakaryocytopoiesis and TPO Production

Mo Yang, M.D.Ph.D, Fanyi Meng, MD, Jie Yu Ye, Yue Xu, Bin Xiao, Beng Chong, MBBS, PhD
Journal: Blood
Blood (2012) 120 (21): 3347.
https://doi.org/10.1182/blood.V120.21.3347.3347
Published: 2012
Journal Articles

Role of PDGF/PDGFR in Regulation of Thrombopoiesis: A Possible Explanation for Imatinib Mesylate-Induced Thrombocytopenia in the Treatment of CML

Mo Yang, M.D.Ph.D, Fanyi Meng, MD, Jie yu Ye, Yue Xu, Bin Xiao, Beng Chong, MBBS, PhD
Journal: Blood
Blood (2012) 120 (21): 3348.
https://doi.org/10.1182/blood.V120.21.3348.3348
Published: 2012
Journal Articles

APS From the Root of Angelica Sinesis Promotes Megakaryocytopoiesis and Thrombopoiesis Through PI3k/Akt Pathway

Mo Yang, M.D.Ph.D, Fanyi Meng, MD, Jie Yu Ye, Yue Xu, Bin Xiao, Beng Chong, MBBS, PhD, Chang Liu, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4648.
https://doi.org/10.1182/blood.V120.21.4648.4648
Published: 2012
Journal Articles

Human Cytomegalovirus Inhibited Megakaryocytic Differentiation, Maturation and Induced Apoptosis in Vitro .

Jian Liang Chen, Godfrey ChiFung Chan, MD, Jie Yu Ye, Zheng Xian He, Qing Wen Wang, Si Nian Pan, Xiao Feng Li, Rui Xia Deng, Mo Yang
Journal: Blood
Blood (2009) 114 (22): 2413.
https://doi.org/10.1182/blood.V114.22.2413.2413
Published: 2009
Journal Articles

Effects of Danggui and Its Component Ferulic Acid On Hematopoiesis and Platelet Production.

Rui Xia Deng, Jie Yu Ye, Chang Charlie Liu, Godfrey ChiFung Chan, MD, Jian Liang Chen, Jian Gang Shen, Mo Yang
Journal: Blood
Blood (2009) 114 (22): 3509.
https://doi.org/10.1182/blood.V114.22.3509.3509
Published: 2009
Journal Articles

Recombinant PDGF-BB Enhances Platelet Recovery in Mice with Radiation Induced Thromobocytopenia.

Jie Yu Ye, Godfrey ChiFung Chan, MD, Shing Chan, Jue Cong Luo, Mo Yang
Journal: Blood
Blood (2008) 112 (11): 1232.
https://doi.org/10.1182/blood.V112.11.1232.1232
Published: 2008
Journal Articles

Angelica Polysaccharides Promotes Thrombopoiesis through the Phosphatidylinositol 3-Kinase/Akt Pathway.

Mo Yang, Godfrey Chifung Chan, MD, Jie Yu Ye, Chang Liu
Journal: Blood
Blood (2008) 112 (11): 1240.
https://doi.org/10.1182/blood.V112.11.1240.1240
Published: 2008
Journal Articles

The Effect and Underlying Mechanism of Melatonin on Platelet Formation and Survival in a Thrombocytopenic Model.

Mo Yang, Min Zhou, Jie Yu Ye, Yiu Fai Cheung, Shing Chan, Shau Yin Ha, Godfrey Chifung Chan, MD
Journal: Blood
Blood (2008) 112 (11): 1241.
https://doi.org/10.1182/blood.V112.11.1241.1241
Published: 2008
Journal Articles

Effects of Serotonin on Proplatelet Formation and F-actin Reorganization in Human Megakaryocytes.

Yuan Shan Cheng, MD, Yuan Sheng Liu, MD, Godfrey ChiFung Chan, MD, Jie Yu Ye, MD, Yu Lung Lau, MD, Mo Yang, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2108.
https://doi.org/10.1182/blood.V110.11.2108.2108
Published: 2007