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Journal Articles

Dual-Method Clone Tracking in Nonhuman Primates Confirms Long-Term Hematopoietic Reconstitution Initiated By Early Engrafting Clones

Jennifer E Adair, PhD, Zachary K. Norgaard, MSc, Kevin G Haworth, PhD, Lauren E Schefter, BA, Kenric Tam, MD, Matthew Porteus, MD PhD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 1475.

https://doi.org/10.1182/blood.V128.22.1475.1475

Published: 2016

Journal Articles

Rapid Expansion of Gene-Marked Lymphocytes in X-SCID Dogs after AMD3100+G-CSF-Based Hematopoietic Stem/Progenitor Cell Mobilization and Intravenous Injection of a Common γ-Chain Expressing Foamy Viral Vector

Frieda Chan, PhD, Olivier Humbert, PhD, Troy Torgerson, MD PhD, Nicholas Hubbard, Patricia O'Donnell, Daniel R Humphrys, B.S., Jennifer E Adair, PhD, Peter Felsburg, Grant D. Trobridge, PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 1348.

https://doi.org/10.1182/blood.V128.22.1348.1348

Published: 2016

Journal Articles

Identification and Characterization of a Distinct, Evolutionarily Conserved HSC Phenotype Associated with and Predicting Multi-Lineage Engraftment

Stefan Radtke, PhD, Morgan A. Giese, BA, Yan-Yi Chan, BA, Zachary K. Norgaard, MSc, Jennifer E Adair, PhD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 1153.

https://doi.org/10.1182/blood.V128.22.1153.1153

Published: 2016

Journal Articles

Gene Therapy for Fanconi Anemia in Seattle: Clinical Experience and Next Steps

Jennifer E Adair, PhD, Pamela S. Becker, MD PhD, Devikha Chandrasekaran, MSc, Grace Choi, BS, Ann E Woolfrey, MD, Lauri Burroughs, MD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 3510.

https://doi.org/10.1182/blood.V128.22.3510.3510

Published: 2016

Journal Articles

Comprehensive Integration Site Analysis of Human Immunodeficiency Virus during In Vivo Infections Reveals Genomic Regions of Enrichment and Clonal Expansion

Kevin G Haworth, PhD, Lauren E Schefter, BA, Zachary K. Norgaard, MSc, Jennifer E Adair, PhD, Hans-Peter Kiem, MD PhD

Blood (2016) 128 (22): 2518.

https://doi.org/10.1182/blood.V128.22.2518.2518

Published: 2016

Journal Articles

Conserved Lineage Development in Human and Nonhuman Primate Hematopoiesis

Stefan Radtke, PhD, Yan-Yi Chan, BA, Morgan A. Giese, BA, Zachary K. Norgaard, MSc, Lauren E Schefter, BA, Jennifer E Adair, PhD, Hans-Peter Kiem, MD FACP

Blood (2016) 128 (22): 2646.

https://doi.org/10.1182/blood.V128.22.2646.2646

Published: 2016

Journal Articles

Pgk-Mediated Expression of Common Gamma Chain Is More Effective Than EF1a for Therapeutic Immune Reconstitution of X-SCID Dogs after In Vivo Gene Therapy with Foamy Virus Vector

Olivier Humbert, PhD, Christopher R Burtner, PhD, Patricia O'Donnell, Daniel R Humphrys, B.S., Nicholas Hubbard, Frieda Chan, PhD, Jennifer E Adair, PhD, Grant D. Trobridge, PhD, Troy Torgerson, MD PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD, Peter Felsburg, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 262.

https://doi.org/10.1182/blood.V126.23.262.262

Published: 2015

Journal Articles

Maintenance of Leukocyte Telomere Length after Transplant and Chemoselection in Macaques with Polyclonal Gene Modified Cell Engraftment

Jennifer E Adair, PhD, Christopher R Burtner, PhD, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 3236.

https://doi.org/10.1182/blood.V126.23.3236.3236

Published: 2015

Journal Articles

In Vivo Selection Unmasks a Dormant Pool of Repopulating Hematopoietic Clones

Jennifer E Adair, PhD, Lauren E Schefter, B.A., Daniel R Humphrys, B.S., Kevin G Haworth, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 242.

https://doi.org/10.1182/blood.V126.23.242.242

Published: 2015

Journal Articles

A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy

Jennifer E Adair, PhD, Kevin G Haworth, PhD, Guy Sauvageau, MD, PhD, Shelly Heimfeld, PhD, Jonah D Hocum, B.S., Grant D. Trobridge, PhD, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 4416.

https://doi.org/10.1182/blood.V126.23.4416.4416

Published: 2015

Journal Articles

Robust Therapeutic Expression of the Common Gamma Chain with the Human Pgk Promoter Using Foamy Virus in Vivo Gene Therapy in a Canine Model of Severe Combined Immunodeficiency

Christopher R Burtner, PhD, Olivier Humbert, PhD, Patricia O'Donnell, Nicholas Hubbard, Daniel Humphrys, Jennifer E Adair, PhD, Grant D Trobridge, PhD, Troy R Torgerson, MD PhD, Andrew M Scharenberg, MD, David Rawlings, MD, Peter J Felsburg, VMD, PhD, Hans-Peter Kiem, MD

Blood (2014) 124 (21): 4794.

https://doi.org/10.1182/blood.V124.21.4794.4794

Published: 2014

Journal Articles

Novel Integrated Autologous Hematopoietic Stem Cell Tracking in Nonhuman Primates Reveals Successive Pattern of Multi-Lineage Reconstitution after Total Body Irradiation

Jennifer E Adair, PhD, Shaina Porter, PhD, Kevin Haworth, PhD, Kenric Tam, BA, Hans-Peter Kiem, MD, Matthew H. Porteus, MD PhD

Blood (2014) 124 (21): 2910.

https://doi.org/10.1182/blood.V124.21.2910.2910

Published: 2014

Journal Articles

Safety Of a Gamma Globin Expressing Lentivirus Vector In a Non-Human Primate Model For Gene Therapy Of Sickle Cell Disease

Hans-Peter Kiem, MD, Paritha Arumugam, PhD, Burtner Christopher, PhD, Jennifer E Adair, PhD, Brian C Beard, PhD, Catherine Fox, MS, Punam Malik, MD

Blood (2013) 122 (21): 2896.

https://doi.org/10.1182/blood.V122.21.2896.2896

Published: 2013

Journal Articles

In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells

Jennifer L Gori, PhD, Jason M Butler, PhD, Devikha Chandrasekaran, MS, Brian C Beard, PhD, Daniel J Nolan, PhD, Michael Ginsberg, PhD, Jennifer E Adair, PhD, Shahin Rafii, MD, Hans-Peter Kiem, MD

Blood (2013) 122 (21): 466.

https://doi.org/10.1182/blood.V122.21.466.466

Published: 2013

Journal Articles

Integration-Mediated Activation of PRDM16 and HMGA2 in Multiple Clones without Adverse Hematopoietic Consequences Following Transplant of Autologous MGMTP140K Gene-Modified CD34 + Cells

Jennifer E Adair, PhD, Brian C Beard, PhD, Grant Trobridge, PhD, Frederic Bushman, PhD, Maciej M Mrugala, MD PhD, Hans-Peter Kiem, MD

Blood (2011) 118 (21): 2053.

https://doi.org/10.1182/blood.V118.21.2053.2053

Published: 2011

NARROW

Dual-Method Clone Tracking in Nonhuman Primates Confirms Long-Term Hematopoietic Reconstitution Initiated By Early Engrafting Clones

Rapid Expansion of Gene-Marked Lymphocytes in X-SCID Dogs after AMD3100+G-CSF-Based Hematopoietic Stem/Progenitor Cell Mobilization and Intravenous Injection of a Common γ-Chain Expressing Foamy Viral Vector

Identification and Characterization of a Distinct, Evolutionarily Conserved HSC Phenotype Associated with and Predicting Multi-Lineage Engraftment

Gene Therapy for Fanconi Anemia in Seattle: Clinical Experience and Next Steps

Comprehensive Integration Site Analysis of Human Immunodeficiency Virus during In Vivo Infections Reveals Genomic Regions of Enrichment and Clonal Expansion

Conserved Lineage Development in Human and Nonhuman Primate Hematopoiesis

Pgk-Mediated Expression of Common Gamma Chain Is More Effective Than EF1a for Therapeutic Immune Reconstitution of X-SCID Dogs after In Vivo Gene Therapy with Foamy Virus Vector

Maintenance of Leukocyte Telomere Length after Transplant and Chemoselection in Macaques with Polyclonal Gene Modified Cell Engraftment

In Vivo Selection Unmasks a Dormant Pool of Repopulating Hematopoietic Clones

A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy

Robust Therapeutic Expression of the Common Gamma Chain with the Human Pgk Promoter Using Foamy Virus in Vivo Gene Therapy in a Canine Model of Severe Combined Immunodeficiency

Novel Integrated Autologous Hematopoietic Stem Cell Tracking in Nonhuman Primates Reveals Successive Pattern of Multi-Lineage Reconstitution after Total Body Irradiation

Safety Of a Gamma Globin Expressing Lentivirus Vector In a Non-Human Primate Model For Gene Therapy Of Sickle Cell Disease

In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells

Integration-Mediated Activation of PRDM16 and HMGA2 in Multiple Clones without Adverse Hematopoietic Consequences Following Transplant of Autologous MGMTP140K Gene-Modified CD34 + Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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