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Jeffrey A. Silverman
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Journal Articles

Recombinant Erwinia asparaginase (JZP458) in acute lymphoblastic leukemia: results from the phase 2/3 AALL1931 study

Clinical Trials & Observations
Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Michelle Zanette, Shirali Agarwal, Robert Iannone, Jeffrey A. Silverman, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2023) 141 (7): 704–712.
https://doi.org/10.1182/blood.2022016923
Published: 2023
Includes: Supplemental data
Journal Articles

Efficacy, Safety, and Population Pharmacokinetic Modeling of Intravenous Recombinant Erwinia Asparaginase (JZP458) in Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma: Results from Study AALL1931

Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Shirali Agarwal, Xiaotian Wu, Robert Iannone, Jeffrey A. Silverman, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2022) 140 (Supplement 1): 8969–8970.
https://doi.org/10.1182/blood-2022-160192
Published: 2022
Journal Articles

Initial Results from a Phase 2/3 Study of Recombinant Erwinia Asparaginase (JZP458) in Patients with Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL) Who Are Allergic/Hypersensitive to E. coli-Derived Asparaginases

Luke Maese, Mignon L. Loh, Tong Lin, Etsuko Aoki, Michelle Zanette, Shirali Agarwal, Jeffrey A. Silverman, Mi Rim Choi, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2021) 138 (Supplement 1): 2307.
https://doi.org/10.1182/blood-2021-147023
Published: 2021
Journal Articles

High-Dose Vincristine Sulfate Liposome Injection (Marqibo ® ) Is Not Associated With Clinically Meaningful Hematologic Toxicity

Olivia R. Deitcher, John Glaspy, MD, Rene Gonzalez, MD, Takami Sato, Agop Bedikian, MD, Karen Segarini, Jeffrey A. Silverman, Ph.D., Steven R. Deitcher, MD
Journal: Blood
Blood (2013) 122 (21): 2676.
https://doi.org/10.1182/blood.V122.21.2676.2676
Published: 2013
Journal Articles

Long Term Results Of a Phase 2 Study Of Vincristine Sulfate Liposome Injection (Marqibo ® ) Substituted For Non-Liposomal Vincristine In CHOP With Or Without Rituximab For Patients With Untreated Aggressive Non-Hodgkin’s Lymphomas

Fredrick B. Hagemeister, MD, Maria Alma Rodriguez, MD, Steven R. Deitcher, MD, Anas Younes, MD, Luis Fayad, MD, Andre Goy, MD, Nam H. Dang, MD, PhD, A Forman, MD, Peter McLaughlin, MD, Barbara Pro, MD, Jorge Enrique Romaguera, Felipe Samaniego, MD, Jeffrey A. Silverman, Ph.D., Andreas H. Sarris, MD, PhD, Fernando Cabanillas, MD
Journal: Blood
Blood (2013) 122 (21): 3033.
https://doi.org/10.1182/blood.V122.21.3033.3033
Published: 2013
Journal Articles

Vincristine Sulfate Liposome Injection (Marqibo ® ) and Rituximab For Patients With Relapsed and Refractory Diffuse Large B-Cell Lymphoma Or Mantle Cell Lymphoma In Need Of Palliative Therapy

Lawrence D. Kaplan, MD, Steven R. Deitcher, MD, Jeffrey A. Silverman, Ph.D., Gareth J Morgan, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4355.
https://doi.org/10.1182/blood.V122.21.4355.4355
Published: 2013
Journal Articles

Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) Facilitates Increased Delivery of Vincristine Sulfate to Target Cancer Tissues.

Jeffrey A. Silverman, Ph.D., Steven R. Deitcher, MD
Journal: Blood
Blood (2012) 120 (21): 2457.
https://doi.org/10.1182/blood.V120.21.2457.2457
Published: 2012
Journal Articles

Neurotoxicity Profile of Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) Monotherapy in Adults with Relapsed Acute Lymphoblastic Leukemia and Universal Prior Standard Vincristine Exposure

Steven R. Deitcher, MD, Jeffrey A. Silverman, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3568.
https://doi.org/10.1182/blood.V120.21.3568.3568
Published: 2012
Journal Articles

Minimal Residual Disease in Adults with Advanced Relapsed Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia Treated with Marqibo ® (vinCRIStine sulfate LIPOSOME injection)

Olivia R. Deitcher, Stuart L. Goldberg, MD, Wendy Stock, MD, Gary J. Schiller, MD, John Lister, MD, Jeffrey A. Silverman, Ph.D., Steven R. Deitcher, MD, Susan O'Brien, M.D.
Journal: Blood
Blood (2012) 120 (21): 4805.
https://doi.org/10.1182/blood.V120.21.4805.4805
Published: 2012
Journal Articles

Design of the Hallmarq Trial, a Phase 3 Study of Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) in Adults with Newly Diagnosed, Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia

Steven R. Deitcher, MD, Jeffrey A. Silverman, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 4300.
https://doi.org/10.1182/blood.V120.21.4300.4300
Published: 2012
Journal Articles

Vincristine Sulfate Liposomes Injection (Marqibo ® ) Facilitates Durable Remissions and Potentially Curative Hematopoietic Stem Cell Transplantation in Adults with Advanced, Relapsed and/or Refractory Acute Lymphoblastic Leukemia

Gary J. Schiller, MD, John Lister, MD, Leonard T. Heffner, MD, Stuart L. Goldberg, MD, Lloyd E. Damon, MD, Jeffrey A. Silverman, Ph.D., Steven R. Deitcher, MD
Journal: Blood
Blood (2011) 118 (21): 4235.
https://doi.org/10.1182/blood.V118.21.4235.4235
Published: 2011
Journal Articles

Marqibo ® (vincristine sulfate liposomes injection; VSLI) Optimizes the Dosing, Delivery, and Pharmacokinetic (PK) Profile of Vincristine Sulfate (VCR) In Adults with Relapsed and Refractory Acute Lymphoblastic Leukemia (ALL)

Jeffrey A Silverman, PhD, Walter E. Aulitzky, MD, John Lister, MD, Lori Maness, M.D., Gary J Schiller, MD, Karen Seiter, MD, Scott Smith, MD, PhD, FACP, Wendy Stock, MD, Dina Ben Yehuda, Steven R. Deitcher, MD
Journal: Blood
Blood (2010) 116 (21): 2142.
https://doi.org/10.1182/blood.V116.21.2142.2142
Published: 2010