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Journal Articles

Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Somedeb Ball, Michael T. Byrne, Melissa A Fischer, Farrukh T. Awan, Ben K. Tomlinson, Tess Stopczynski, Lokesh Patil, Christine J. Gu, Chris Leonardi, Katherine J. Walsh, Gregory Dan Ayers, Ashwin Kishtagari, Kateryna Fedorov, Markus D. Lacher, Joseph Wagner, Sanjay R Mohan, Michael R. Savona

Blood (2024) 144 (Supplement 1): 6012.

https://doi.org/10.1182/blood-2024-209403

Published: 2024

Journal Articles

Durable Remission and Long-Term Survival in Relapsed/Refractory (r/r) AML Patients Treated with Guadecitabine, Median Survival Not Reached for Responders after Long Term Follow up from Phase 2 Study of 103 Patients

Elizabeth A. Griffiths, MD, Hagop M. Kantarjian, MD, Casey L. O'Connell, MD, Karen W.L. Yee, MD, Wendy Stock, MD, Naval G. Daver, MD, Elias Jabbour, MD, Ellen K. Ritchie, MD, Jean-Pierre Issa, MD, Katherine J. Walsh, MD, David A. Rizzieri, MD, Scott D. Lunin, MD, Xiang Yao Su, PhD, Mohammad Azab, MD, Gail J. Roboz, MD

Blood (2019) 134 (Supplement_1): 1319.

https://doi.org/10.1182/blood-2019-131394

Published: 2019

Journal Articles

Landmark Response and Survival Analyses from 102 MDS and CMML Patients Treated with Guadecitabine in a Phase 2 Study Showing That Maximum Response and Survival Is Best Achieved with Adequate Treatment Duration

Michael R. Savona, MD, Hagop M. Kantarjian, MD, Gail J. Roboz, MD, Casey L. O'Connell, MD, Katherine J. Walsh, MD, Raoul Tibes, MD PhD, Karen W.L. Yee, MD, Wendy Stock, MD, Elizabeth A. Griffiths, MD, Elias Jabbour, MD, Scott D. Lunin, MD, Todd L. Rosenblat, MD MS, Nikolai A. Podoltsev, MD PhD, Jean-Pierre Issa, MD, Xiang Yao Su, PhD, Mohammad Azab, MD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 2957.

https://doi.org/10.1182/blood-2019-129962

Published: 2019

Journal Articles

Landmark Response and Survival Analyses from 206 AML Patients Treated with Guadecitabine in a Phase 2 Study Demonstrate the Importance of Adequate Treatment Duration to Maximize Response and Survival Benefit. Survival Benefit Not Restricted to Patients with Objective Response

Karen W.L. Yee, MD, Gail J. Roboz, MD, Casey L. O'Connell, MD, Elizabeth A. Griffiths, MD, Raoul Tibes, MD PhD, Katherine J. Walsh, MD, Wendy Stock, MD, Guillermo Garcia-Manero, MD, Michael R. Savona, MD, Farhad Ravandi, MD, Naval G. Daver, MD, Elias Jabbour, MD, Todd L. Rosenblat, MD MS, Jean-Pierre Issa, MD, Xiang Yao Su, PhD, Mohammad Azab, MD, Hagop M. Kantarjian, MD

Blood (2019) 134 (Supplement_1): 3846.

https://doi.org/10.1182/blood-2019-129845

Published: 2019

Journal Articles

Long Term Results of a Randomized Phase 2 Dose-Response Study of Guadecitabine, a Novel Subcutaneous (SC) Hypomethylating Agent (HMA), in 102 Patients with Intermediate or High Risk Myelodysplastic Syndromes (MDS) or Chronic Myelomonocytic Leukemia (CMML)

Blood (2018) 132 (Supplement 1): 231.

https://doi.org/10.1182/blood-2018-99-110465

Published: 2018

Journal Articles

Predictors of Response and Survival in 206 AML Patients Treated with Guadecitabine in a Phase 2 Study

Hagop M. Kantarjian, MD, Gail J. Roboz, MD, Patricia L Kropf, MD, Elias J. Jabbour, MD, Karen W.L. Yee, MD, Casey L. O'Connell, MD, Guillermo Garcia-Manero, MD, Elizabeth A. Griffiths, MD, Katherine J. Walsh, MD, Wendy Stock, MD, Raoul Tibes, MD PhD, Nikolai A. Podoltsev, MD PhD, Yong Hao, Valerie Ahanonu, Mohammad Azab, MD, Jean-Pierre Issa, MD

Blood (2017) 130 (Supplement 1): 3854.

https://doi.org/10.1182/blood.V130.Suppl_1.3854.3854

Published: 2017

Journal Articles

A Phase 1 Clinical Trial of Selinexor in Combination with Decitabine in Patients with Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia

Bhavana Bhatnagar, DO, Rebecca B. Klisovic, MD, Alison R. Walker, MD MPH, Sumithra Vasu, MBBS, Alice S. Mims, MD MSCR, Katherine J. Walsh, MD, Gregory K. Behbehani, MD PhD, James S. Blachly, MD, Molly Vittorio, Qiuhong Zhao, Amy S. Ruppert, MAS, Shelley Orwick, BS, Parvathi Ranganathan, PhD, John C. Byrd, MD, William Blum, MD, Ramiro Garzon, MD

Blood (2016) 128 (22): 1651.

https://doi.org/10.1182/blood.V128.22.1651.1651

Published: 2016

Journal Articles

A Novel Regimen for Acute Myeloid Leukemia with MLL Partial Tandem Duplication: Results of a Phase 1 Study NCI 8485

Alice S. Mims, MD MSCR, Rebecca B Klisovic, MD, Ramiro Garzon, MD, Alison R. Walker, MD MPH, Steven M. Devine, MD, Katherine J. Walsh, MD, Sumithira Vasu, MBBS, Susan P. Whitman, PhD, Guido Marcucci, MD, Nyla A. Heerema, PhD, Michael A. Caligiuri, MD, Clara D. Bloomfield, MD, John C. Byrd, MD, Richard Piekarz, PhD MD, Michael R. Grever, MD, William Blum, MD

Blood (2016) 128 (22): 900.

https://doi.org/10.1182/blood.V128.22.900.900

Published: 2016

Journal Articles

Long Term Survival and Clinical Complete Responses of Various Prognostic Subgroups in 103 Relapsed/Refractory Acute Myeloid Leukemia (r/r AML) Patients Treated with Guadecitabine (SGI-110) in Phase 2 Studies

Naval Daver, MD, Hagop M. Kantarjian, MD, Gail J. Roboz, Patricia L. Kropf, MD, Karen W.L. Yee, MD, Casey L. O'Connell, MD, Elizabeth A. Griffiths, MD, Elias J. Jabbour, MD, Wendy Stock, Katherine J. Walsh, MD, David A. Rizzieri, MD, Jesus G. Berdeja, MD, Xiang Yao Su, PhD, Mohammad Azab, MD, Jean-Pierre Issa, MD

Blood (2016) 128 (22): 904.

https://doi.org/10.1182/blood.V128.22.904.904

Published: 2016

Journal Articles

Interim Results of a Phase 1b/2 Study of Entospletinib (GS-9973) Monotherapy and in Combination with Chemotherapy in Patients with Acute Myeloid Leukemia

Alison R. Walker, MD MPH, Bhavana Bhatnagar, DO, A. Mario Q. Marcondes, MD, Julie DiPaolo, PhD, Sumithra Vasu, MBBS, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Katherine J. Walsh, MD, Renee Canning, RN, Gregory K. Behbehani, MD PhD, Ramiro Garzon, MD, James S. Blachly, MD, Amy J. Johnson, PhD, Esteban Abella-Dominicis, John C. Byrd, MD, William Blum, MD

Blood (2016) 128 (22): 2831.

https://doi.org/10.1182/blood.V128.22.2831.2831

Published: 2016

Journal Articles

Primary antifungal prophylaxis during curative-intent therapy for acute myeloid leukemia

Anna B. Halpern, Gary H. Lyman, Thomas J. Walsh, Dimitrios P. Kontoyiannis, Roland B. Walter

Blood (2015) 126 (26): 2790–2797.

https://doi.org/10.1182/blood-2015-07-627323

Published: 2015

Includes: Supplemental data

Journal Articles

Comparison of Efficacy and Safety Results in 103 Treatment-Naïve Acute Myeloid Leukemia (TN-AML) Patients Not Candidates for Intensive Chemotherapy Using 5-Day and 10-Day Regimens of Guadecitabine (SGI-110), a Novel Hypomethylating Agent (HMA)

Blood (2015) 126 (23): 458.

https://doi.org/10.1182/blood.V126.23.458.458

Published: 2015

Journal Articles

Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation

John R. Wingard, Shelly L. Carter, Thomas J. Walsh, Joanne Kurtzberg, Trudy N. Small, Lindsey R. Baden, Iris D. Gersten, Adam M. Mendizabal, Helen L. Leather, Dennis L. Confer, Richard T. Maziarz, Edward A. Stadtmauer, Javier Bolaños-Meade, Janice Brown, John F. DiPersio, Michael Boeckh, Kieren A. Marr, for The Blood and Marrow Transplant Clinical Trials Network

Blood (2010) 116 (24): 5111–5118.

https://doi.org/10.1182/blood-2010-02-268151

Published: 2010

Includes: Supplemental data

Journal Articles

Upregulated JAK/STAT Signaling Represents a Major Mode of Resistance to HDAC Inhibition In Lymphoma and Provides a Rationale for Novel Combination Therapy

Jason Smith, Katherine J. Walsh, MD, Cassandra L Jacobs, MS, Qingquan Liu, PhD, Siyao Fan, Amee Patel, Sandeep Dave, MD

Blood (2010) 116 (21): 434.

https://doi.org/10.1182/blood.V116.21.434.434

Published: 2010

Journal Articles

Hedgehog Pathway Inhibition Is a Novel Therapeutic Approach in Lymphomas and Its Efficacy is Inversely Related to PI3 Kinase Inhibition

Katherine J. Walsh, MD, Siyao Fan, Amee Patel, Cassandra L Jacobs, MS, Jason Smith, Qingquan Liu, PhD, Sandeep Dave, MD

Blood (2010) 116 (21): 1848.

https://doi.org/10.1182/blood.V116.21.1848.1848

Published: 2010

Journal Articles

PI3K Inhibitors Inhibit Lymphoma Growth by Downregulation of MYC-Dependent Proliferation.

Katherine J. Walsh, MD, Siyao Fan, Amee Patel, Cassandra L. Jacobs, MS, Jason L. Smith, MD, MA, Qingquan Liu, David A. Rizzieri, MD, Sandeep Dave, MD

Blood (2009) 114 (22): 1697.

https://doi.org/10.1182/blood.V114.22.1697.1697

Published: 2009

Journal Articles

Histone Deacetylase Inhibition Using LBH589 Is Effective in Lymphoma and Results in Down-Regulation of the NF-KB Pathway.

Jason L. Smith, MD, MA, Amee Patel, Siyao Fan, Cassandra L. Jacobs, MS, Katherine J. Walsh, MD, Qingquan Liu, David A. Rizzieri, MD, Sandeep Dave, MD

Blood (2009) 114 (22): 3730.

https://doi.org/10.1182/blood.V114.22.3730.3730

Published: 2009

Journal Articles

Risk Factors for Candidemia in Pediatric Oncology Patients.

Theoklis E Zaoutis, MD, MSCE, Priya A Prasad, MPH, A. Russell Localio, JD, PhD, Anne Reilly, MD, Louis M Bell, MD, Thomas J Walsh, MD, Robert Gross, MD

Blood (2009) 114 (22): 4735.

https://doi.org/10.1182/blood.V114.22.4735.4735

Published: 2009

Journal Articles

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

Jotin Marango, Manabu Shimoyama, Hitomi Nishio, Julia A. Meyer, Dong-Joon Min, Andres Sirulnik, Yolanda Martinez-Martinez, Marta Chesi, P. Leif Bergsagel, Ming-Ming Zhou, Samuel Waxman, Boris A. Leibovitch, Martin J. Walsh, Jonathan D. Licht

Blood (2008) 111 (6): 3145–3154.

https://doi.org/10.1182/blood-2007-06-092122

Published: 2008

Journal Articles

Results of a Randomized, Double-Blind Trial of Fluconazole (FLU) vs. Voriconazole (VORI) for the Prevention of Invasive Fungal Infections (IFI) in 600 Allogeneic Blood and Marrow Transplant (BMT) Patients.

John R. Wingard, Shelly L. Carter, Thomas J. Walsh, Joanne Kurtzberg, Trudy N. Small, Iris D. Gersten, Adam M. Mendizabal, Helen Leather, Dennis L. Confer, Lindsey R. Baden, Richard T. Maziarz, Edward A. Stadtmauer, Javier Bolanos-Meade, Janice Brown, John F. DiPersio, Michael Boeckh, Kieren A. Marr

Blood (2007) 110 (11): 163.

https://doi.org/10.1182/blood.V110.11.163.163

Published: 2007

NARROW

Application of a Phenotype-Based Predictive Analytic in a Phase Ib Study of Selinexor and Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Durable Remission and Long-Term Survival in Relapsed/Refractory (r/r) AML Patients Treated with Guadecitabine, Median Survival Not Reached for Responders after Long Term Follow up from Phase 2 Study of 103 Patients

Landmark Response and Survival Analyses from 102 MDS and CMML Patients Treated with Guadecitabine in a Phase 2 Study Showing That Maximum Response and Survival Is Best Achieved with Adequate Treatment Duration

Landmark Response and Survival Analyses from 206 AML Patients Treated with Guadecitabine in a Phase 2 Study Demonstrate the Importance of Adequate Treatment Duration to Maximize Response and Survival Benefit. Survival Benefit Not Restricted to Patients with Objective Response

Long Term Results of a Randomized Phase 2 Dose-Response Study of Guadecitabine, a Novel Subcutaneous (SC) Hypomethylating Agent (HMA), in 102 Patients with Intermediate or High Risk Myelodysplastic Syndromes (MDS) or Chronic Myelomonocytic Leukemia (CMML)

Predictors of Response and Survival in 206 AML Patients Treated with Guadecitabine in a Phase 2 Study

A Phase 1 Clinical Trial of Selinexor in Combination with Decitabine in Patients with Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia

A Novel Regimen for Acute Myeloid Leukemia with MLL Partial Tandem Duplication: Results of a Phase 1 Study NCI 8485

Long Term Survival and Clinical Complete Responses of Various Prognostic Subgroups in 103 Relapsed/Refractory Acute Myeloid Leukemia (r/r AML) Patients Treated with Guadecitabine (SGI-110) in Phase 2 Studies

Interim Results of a Phase 1b/2 Study of Entospletinib (GS-9973) Monotherapy and in Combination with Chemotherapy in Patients with Acute Myeloid Leukemia

Primary antifungal prophylaxis during curative-intent therapy for acute myeloid leukemia

Comparison of Efficacy and Safety Results in 103 Treatment-Naïve Acute Myeloid Leukemia (TN-AML) Patients Not Candidates for Intensive Chemotherapy Using 5-Day and 10-Day Regimens of Guadecitabine (SGI-110), a Novel Hypomethylating Agent (HMA)

Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation

Upregulated JAK/STAT Signaling Represents a Major Mode of Resistance to HDAC Inhibition In Lymphoma and Provides a Rationale for Novel Combination Therapy

Hedgehog Pathway Inhibition Is a Novel Therapeutic Approach in Lymphomas and Its Efficacy is Inversely Related to PI3 Kinase Inhibition

PI3K Inhibitors Inhibit Lymphoma Growth by Downregulation of MYC-Dependent Proliferation.

Histone Deacetylase Inhibition Using LBH589 Is Effective in Lymphoma and Results in Down-Regulation of the NF-KB Pathway.

Risk Factors for Candidemia in Pediatric Oncology Patients.

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

Results of a Randomized, Double-Blind Trial of Fluconazole (FLU) vs. Voriconazole (VORI) for the Prevention of Invasive Fungal Infections (IFI) in 600 Allogeneic Blood and Marrow Transplant (BMT) Patients.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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