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Iris Appelmann, MD
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Journal Articles

Interplay between PI3K/mTOR Signaling and IRE1a-XBP1 Promotes Survival of Pre-B NRAS G12D all Cells Providing a Therapeutic Vulnerability for the "Undruggable" Driver RAS

Iris Appelmann, MD, Azam Salimi, Michael Huber, PhD, Mirle Schemionek, PhD, Margherita Vieri, PhD, Tim H Brümmendorf, MD, John B. Patterson, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-140299
Published: 2020
Journal Articles

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Margherita Vieri, MSc, Christian Preisinger, Mirle Schemionek, Azam Salimi, John B. Patterson, Afshin Samali, Tim H Brümmendorf, MD, Iris Appelmann, MD, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4674.
https://doi.org/10.1182/blood-2018-99-110967
Published: 2018
Journal Articles

Suppression of EZH2 Accelerates MYC-Driven Lymphomagenesis By Inhibition of Apoptosis

Iris Appelmann, MD, Claudio Scuoppo, PhD, Vishal Thapar, PhD, Daniela Ledezma, M.S., Amaia Lujambio, PhD, Scott W. Lowe, PhD, Agustin Chicas, PhD
Journal: Blood
Blood (2014) 124 (21): 3009.
https://doi.org/10.1182/blood.V124.21.3009.3009
Published: 2014
Journal Articles

Prevention Of Minimal Residual Disease In Ph+ ALL

Iris Appelmann, MD, Elisa DeStanchina, PhD, Gregory Carbonetti, BS, Chong Chen, PhD, Scott W. Lowe, PhD, Charles J. Sherr, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1265.
https://doi.org/10.1182/blood.V122.21.1265.1265
Published: 2013