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Journal Articles

Breakthrough Hemolysis in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Ravulizumab: Results of a 52-Week Extension from Two Phase 3 Studies

Anita Hill, MD PhD, Caroline I. Piatek, Régis Peffault de Latour, MD PhD, Lily LL Wong, MD FRCPath, Richard A. Wells, MD DPhil, Robert A. Brodsky, MD, Jin Seok Kim, MD PhD, Junichi Nishimura, MD PhD, Philip Kuriakose, MD, Rodrigo Pavani, Peng Liu, Stephan Ortiz, RPh, PhD, Hubert Schrezenmeier, MD, Jong-Wook Lee, MD PhD, Austin Kulasekararaj, MDMBBS,MRCP,FRCPath

Blood (2019) 134 (Supplement_1): 952.

https://doi.org/10.1182/blood-2019-128929

Published: 2019

Journal Articles

Efficacy of Eculizumab in Pediatric Patients with Paroxysmal Nocturnal Hemoglobinuria in the International PNH Registry

Álvaro Urbano-Ispizua, MD PhD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Marije Bartels, MD PhD, Christopher J. Patriquin, MD MSc, FRCPC, Britta Hoechsmann, MD, Alexey A. Maschan, MD, Amanda Wilson, PhD, Philippe Gustovic, MD, Hubert Schrezenmeier, MD

Blood (2018) 132 (Supplement 1): 3614.

https://doi.org/10.1182/blood-2018-99-111306

Published: 2018

Journal Articles

A Prospective Analysis of Breakthrough Hemolysis in 2 Phase 3 Randomized Studies of Ravulizumab (ALXN1210) Versus Eculizumab in Adults with Paroxysmal Nocturnal Hemoglobinuria

Robert A. Brodsky, MD, Regis Peffault De Latour, Scott T. Rottinghaus, MD, Alexander Röth, MD, Antonio M. Risitano, MD PhD, Ilene C. Weitz, MD, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, Jaroslaw P. Maciejewski, Jeffrey Szer, MBBS, Jong-Wook Lee, MD PhD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Lori Volles, MD, Andrew I. Damokosh, PhD, Stephan Ortiz, RPh, PhD, Lori Shafner, PhD, Anita Hill, MD PhS, Hubert Schrezenmeier, MD

Blood (2018) 132 (Supplement 1): 2330.

https://doi.org/10.1182/blood-2018-99-110874

Published: 2018

Journal Articles

Expression of PD-L1 in Leukemic Progenitor Cells Defines NPM1 Mutated AML As a Potential Subgroup for PD1/PD-L1 Directed Immunotherapy

Jochen Greiner, Vanessa Schneider, Dr. rer. nat., Hubert Schrezenmeier, MD, Markus Wiesneth, MD, Lars Bullinger, MD, Hartmut Döhner, MD, Susanne Hofmann, MD, Marlies Götz

Blood (2018) 132 (Supplement 1): 2734.

https://doi.org/10.1182/blood-2018-99-111458

Published: 2018

Journal Articles

Long-Term Follow-up of the Randomized Controlled Study in Patients with Newly Diagnosed Severe Aplastic Anemia Treated with ATG, Cyclosporine, with or without G-CSF: On Behalf of the SAA Working Party of the EBMT

André Tichelli, MD, Regis Peffault De Latour, Jakob R. Passweg, MD PhD, Cora Knol, Gérard Socié, MDPhD, Judith Marsh, Britta Hoechsmann, MD, Hubert Schrezenmeier, MD, Andrea Bacigalupo, MD, Sujith Samarasinghe, Alicia Rovo, MD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Dirk-Jan Eikema, Paul Bosman, Peter Bader, MD PhD, Antonio M. Risitano, MD PhD, Carlo Dufour, MD

Blood (2018) 132 (Supplement 1): 1307.

https://doi.org/10.1182/blood-2018-99-111811

Published: 2018

Journal Articles

The Role of HLA-E Polymorphism in Acute Leukemia Patients Receiving a 10/10 HLA Matched Unrelated HSCT

Chrysanthi Tsamadou, MD, Tao Wang, PhD, Daniel Fürst, MD PhD, Stephanie J. Lee, MD MPH, Stephen R. Spellman, Katharina Fleischhauer, Katharine C. Hsu, MD PhD, Sophie Paczesny, MD PhD, Michael R Verneris, MD, Christine Neuchel, PhD, Hubert Schrezenmeier, MD, Joannis Mytilineos, MD PhD

Blood (2018) 132 (Supplement 1): 310.

https://doi.org/10.1182/blood-2018-99-113432

Published: 2018

Journal Articles

Optimization of Dose Regimen for ALXN1210, a Novel Complement C5 Inhibitor, in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Results of 2 Phase 1/2 Studies

Alexander Roeth, MD, Scott T. Rottinghaus, MD, Anita Hill, MBChB (Hons), PhD, Jin Seok Kim, MD PhD, Hubert Schrezenmeier, MD, Louis Terriou, MD, Alvaro Urbano-Ispizua, MD, Richard A. Wells, MD DPhil, Jun Ho Jang, MD PhD, Jeff Szer, MB, BS, FRACP, Rasha Aguzzi, MS, Eric Scott Bachman, MD PhD, Andrew I. Damokosh, PhD, Lori Shafner, PhD, Jong-Wook Lee, MD

Blood (2017) 130 (Supplement 1): 3482.

https://doi.org/10.1182/blood.V130.Suppl_1.3482.3482

Published: 2017

Journal Articles

Efficacy of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and High Disease Activity with or without History of Aplastic Anemia in the International PNH Registry

Jong-Wook Lee, MD, Regis Peffault De Latour, MD PhD, Robert A. Brodsky, MD, Jun Ho Jang, MD PhD, Anita Hill, MBChB (Hons), PhD, Alexander Roeth, MD, Hubert Schrezenmeier, MD, Amanda Wilson, MPH, PhD, Jing L. Marantz, MD PhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 3487.

https://doi.org/10.1182/blood.V130.Suppl_1.3487.3487

Published: 2017

Journal Articles

Analysis of Baseline Clinical Characteristics and Disease Burden in Patients Enrolled in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Hubert Schrezenmeier, MD, Jaroslaw P. Maciejewski, PhD MD FACP, Alexander Roeth, MD, David J. Araten, MD, Yuzuru Kanakura, MD PhD, Loree Larratt, MD FRCP(C), Jamile M. Shammo, MD FASCP, FACP, Amanda Wilson, MPH, PhD, Gilda Shayan, Peter Hillmen, MBChB, PhD

Blood (2017) 130 (Supplement 1): 3488.

https://doi.org/10.1182/blood.V130.Suppl_1.3488.3488

Published: 2017

Journal Articles

Peptide Vaccination Against Cytomegalovirus (CMV) Elicits Immunological and Clinical Responses after Allogeneic Stem Cell Transplantation Even from a CMV Seronegative Donor

Blood (2016) 128 (22): 2519.

https://doi.org/10.1182/blood.V128.22.2519.2519

Published: 2016

Journal Articles

Clinical Benefit of Eculizumab in Patients with No Transfusion History in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Antonio Medina Almeida, MD PhD, Camille L. Bedrosian, MD, Alexander Cole, DSc, MPH, Petra Muus, MD PhD, Hubert Schrezenmeier, MD, Jeff Szer, MB, BS, FRACP, Alvaro Urbano-Ispizua, MD PhD, Wendell F. Rosse, MD

Blood (2015) 126 (23): 3340.

https://doi.org/10.1182/blood.V126.23.3340.3340

Published: 2015

Journal Articles

Different Clinical Characteristics of Paroxysmal Nocturnal Hemoglobinuria in Pediatric and Adult Patients

Alvaro Urbano-Ispizua, Petra Muus, MD PhD, Hubert Schrezenmeier, MD, Antonio Medina Almeida, MD PhD, Amanda Wilson, MPH, PhD, Russell E. Ware, MD PhD

Blood (2015) 126 (23): 3341.

https://doi.org/10.1182/blood.V126.23.3341.3341

Published: 2015

Journal Articles

Complement Inhibition with Eculizumab in Patients with Cold Agglutinin Disease (CAD): Results from a Prospective Phase II Trial (DECADE Trial)

Alexander Röth, MD, Martin Bommer, MD, Andreas Hüttmann, MD, Dörte Herich-Terhürne, Nils Kuklik, PhD, Lenz Veronika, Hubert Schrezenmeier, MD, Ulrich Dührsen, MD

Blood (2015) 126 (23): 274.

https://doi.org/10.1182/blood.V126.23.274.274

Published: 2015

Journal Articles

Granzyme B Is a Key Regulator of Plasmacytoid Dendritic Cell Immunogenicity

Bernd Jahrsdörfer, MD, Thamara Beyer, Hubert Schrezenmeier, MD, Klaus-Michael Debatin, MD, Dorit Fabricius, MD

Blood (2014) 124 (21): 4127.

https://doi.org/10.1182/blood.V124.21.4127.4127

Published: 2014

Journal Articles

Eculizumab Treatment Improves Outcomes of Pregnancy in Patients with Paroxysmal Nocturnal Hemoglobinuria

Richard J Kelly, MBChB, PhD, Britta Höchsmann, MD, Austin Kulasekararaj, Sophie de Guibert, MD, Alexander Röth, MD, Ilene C Weitz, MD, Elina Armstrong, MD PhD, Anita Hill, MBChB, PhD, Antonio M. Risitano, MD PhD, Christopher J Patriquin, MDFRCPC, Louis Terriou, MD, Petra Muus, MD PhD, Michelle P Turner, MS in Biostatistics, Hubert Schrezenmeier, MD PhD, Jeffrey Szer, MB BS FRACP, Regis Peffault de Latour, MD PhD

Blood (2014) 124 (21): 4393.

https://doi.org/10.1182/blood.V124.21.4393.4393

Published: 2014

Journal Articles

Similar Outcome of Upfront Unrelated and Matched Sibling Donor Hematopoietic Stem Cell Transplantation in Idiopathic Aplastic Anaemia of Childhood and Adolescence: A Cohort Controlled Study on Behalf of the UK Paediatric BMT WP, of the PD WP and of the SAA WP of the EBMT

Blood (2014) 124 (21): 256.

https://doi.org/10.1182/blood.V124.21.256.256

Published: 2014

Journal Articles

IL-21-Mediated Generation of Human Regulatory B Cells Occurs Independently of CD40 Signaling

Bernd Jahrsdörfer, MD, Christof Kaltenmeier, Ali Gawanbacht, Thamara Beyer, Catharina Schütz, MD, Manfred Hönig, MD, Frank Kirchhoff, PhD, Hubert Schrezenmeier, MD

Blood (2014) 124 (21): 1413.

https://doi.org/10.1182/blood.V124.21.1413.1413

Published: 2014

Journal Articles

Outcome Of Aplastic Anemia In Adolescence. A Survey Of The Severe Aplastic Anemia Working Party (SAAWP) Of The European Blood and Bone Marrow Transplant Group (EBMT)

Carlo Dufour, MD, Marta Pillon, MD, Jakob Passweg, MD, Gérard Socié, MD, PhD, Andrea Bacigalupo, MD, Genny Franceschetto, Rosi Oneto, Antonio M. Risitano, MD, PhD, Regis Peffault de la Tour, MD, PhD, Andre Tichelli, MD, Alicia Rovo, MD, Christina Peters, Britta Hochsmann, MD, Hubert Schrezenmeier, MD, PhD, Mahmoud D. Aljurf, MD, Judith Marsh

Blood (2013) 122 (21): 2481.

https://doi.org/10.1182/blood.V122.21.2481.2481

Published: 2013

Journal Articles

Development Of a Disease Specific Quality Of Life Questionnaire For Patients With Aplastic Anemia and/Or Paroxysmal Nocturnal Hemoglobinuria (QLQ-AA/PNH)

Martha Groth, Susanne Singer, PhD, Cathrin Niedeggen, Andrea Petermann-Meyer, MD, Alexander Roeth, MD, Hubert Schrezenmeier, MD, Britta Höchsmann, MD, Tim H. Brümmendorf, MD, Jens Panse, MD

Blood (2013) 122 (21): 1680.

https://doi.org/10.1182/blood.V122.21.1680.1680

Published: 2013

Journal Articles

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

Vanessa Schneider, Lars Bullinger, MD, PhD, Lu Zhang, Markus Rojewski, Markus Wiesneth, Susanne Hofmann, Marlies Goetz, Hubert Schrezenmeier, MD, Ulla Botzenhardt, Thomas F.E. Barth, Konstanze Doehner, MD, Hartmut Doehner, MD, Jochen Greiner, MD

Blood (2013) 122 (21): 2624.

https://doi.org/10.1182/blood.V122.21.2624.2624

Published: 2013

NARROW

Breakthrough Hemolysis in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Ravulizumab: Results of a 52-Week Extension from Two Phase 3 Studies

Efficacy of Eculizumab in Pediatric Patients with Paroxysmal Nocturnal Hemoglobinuria in the International PNH Registry

A Prospective Analysis of Breakthrough Hemolysis in 2 Phase 3 Randomized Studies of Ravulizumab (ALXN1210) Versus Eculizumab in Adults with Paroxysmal Nocturnal Hemoglobinuria

Expression of PD-L1 in Leukemic Progenitor Cells Defines NPM1 Mutated AML As a Potential Subgroup for PD1/PD-L1 Directed Immunotherapy

Long-Term Follow-up of the Randomized Controlled Study in Patients with Newly Diagnosed Severe Aplastic Anemia Treated with ATG, Cyclosporine, with or without G-CSF: On Behalf of the SAA Working Party of the EBMT

The Role of HLA-E Polymorphism in Acute Leukemia Patients Receiving a 10/10 HLA Matched Unrelated HSCT

Optimization of Dose Regimen for ALXN1210, a Novel Complement C5 Inhibitor, in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH): Results of 2 Phase 1/2 Studies

Efficacy of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and High Disease Activity with or without History of Aplastic Anemia in the International PNH Registry

Analysis of Baseline Clinical Characteristics and Disease Burden in Patients Enrolled in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Peptide Vaccination Against Cytomegalovirus (CMV) Elicits Immunological and Clinical Responses after Allogeneic Stem Cell Transplantation Even from a CMV Seronegative Donor

Clinical Benefit of Eculizumab in Patients with No Transfusion History in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Different Clinical Characteristics of Paroxysmal Nocturnal Hemoglobinuria in Pediatric and Adult Patients

Complement Inhibition with Eculizumab in Patients with Cold Agglutinin Disease (CAD): Results from a Prospective Phase II Trial (DECADE Trial)

Granzyme B Is a Key Regulator of Plasmacytoid Dendritic Cell Immunogenicity

Eculizumab Treatment Improves Outcomes of Pregnancy in Patients with Paroxysmal Nocturnal Hemoglobinuria

Similar Outcome of Upfront Unrelated and Matched Sibling Donor Hematopoietic Stem Cell Transplantation in Idiopathic Aplastic Anaemia of Childhood and Adolescence: A Cohort Controlled Study on Behalf of the UK Paediatric BMT WP, of the PD WP and of the SAA WP of the EBMT

IL-21-Mediated Generation of Human Regulatory B Cells Occurs Independently of CD40 Signaling

Outcome Of Aplastic Anemia In Adolescence. A Survey Of The Severe Aplastic Anemia Working Party (SAAWP) Of The European Blood and Bone Marrow Transplant Group (EBMT)

Development Of a Disease Specific Quality Of Life Questionnaire For Patients With Aplastic Anemia and/Or Paroxysmal Nocturnal Hemoglobinuria (QLQ-AA/PNH)

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

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American Society of Hematology

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American Society of Hematology

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