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Huaxian Ma, MS
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Journal Articles

The Novel Dihydroorotate Dehydrogenase (DHODH) Inhibitor PTC299 Inhibit De Novo Pyrimidine Synthesis with Broad Anti-Leukemic Activity Against Acute Myeloid Leukemia

Sujan Piya, PhD, Marla Weetall, PhD, Josephine Sheedy, BS, MSc, Balmiki Ray, PhD, Huaxian Ma, MS, Kensuke Kojima, MD PhD, Vivian Ruvolo, MS, Mahesh Basyal, BS, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Gautam Borthakur, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-139940
Published: 2020
Journal Articles

AXL/Mertk Inhibitor ONO-7475 Potently Synergizes with BCL2 Inhibitor ABT-199, Overcomes ABT-199 Resistance Mechanisms, and Kills FLT3 ITD AML Cells

Sean M Post, PhD, Huaxian Ma, MS, Vivian Ruvolo, Xiaorui Zhang, BS, Tomoko Yasuhiro, Kohei Tanaka, Ryohei Kozaki, Toshio Yoshizawa, PhD, Jorge E. Cortes, MD, Courtney D. DiNardo, MDMSc, Marina Y Konopleva, MD PhD, Steven M. Kornblau, MD, Joseph D. Khoury, MD, Michael Andreeff, MD PhD, Peter P. Ruvolo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2550.
https://doi.org/10.1182/blood-2019-128626
Published: 2019
Journal Articles

Combination Therapy with BTK Inhibitor Plus Anti-PD-1 Antibody Results in a Hyperprogressor Phenotype in a Mouse Model of CLL

Aidi Gu, PhD, Huaxian Ma, MS, Xiaorui Zhang, BS, Prerna Malaney, PhD, Miguel Gallardo, PhD, Jingwei Liu, MD, Sattva S. Neelapu, MD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4416.
https://doi.org/10.1182/blood-2018-99-118773
Published: 2018
Journal Articles

Mcl-1/CDK9 Targeting By AZD5991/AZD4573 Overcomes Intrinsic and Acquired Venetoclax Resistance in Vitro and In Vivo in PDX Model of AML through Modulation of Cell Death and Metabolic Functions

Bing Z Carter, PhD, Po Yee Mak, Wenjing Tao, Mark Warmoes, Philip L Lorenzi, PhD, Duncan Mak, BSc, MPhil, Vivian Ruvolo, MS, Xiangmeng Wang, Huaxian Ma, MS, Hong Mu, MD PhD, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 768.
https://doi.org/10.1182/blood-2018-99-113491
Published: 2018
Journal Articles

hnRNP K Overexpression Drives Myeloid Malignancy Via Interaction with RUNX1

Marisa J Hornbaker, BS, Prerna Malaney, PhD, Xiaorui Zhang, BS, Ruizhi Duan, M.Sc., Vrutant Shah, PhD, Shelley Herbrich, MS, Miguel Gallardo, PhD, Rodrigo Jacamo, PhD, Todd Link, PhD, Huaxian Ma, MS, Sanzhar Alybayev, MS, Steven M. Kornblau, MD, Peter Hu, PhD, Dos Sarbassov, PhD, Rashmi Kanagal-Shamanna, MD, Carlos E. Bueso-Ramos, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2622.
https://doi.org/10.1182/blood-2018-99-117387
Published: 2018
Journal Articles

TAM Inhibitor ONO-7475 Combination with Sorafenib Is Effective Using in Vitro and In Vivo Models of FLT3 ITD Acute Myeloid Leukemia

Peter P. Ruvolo, PhD, Huaxian Ma, MS, Vivian Ruvolo, MS, Xiaorui Zhang, BS, Hong Mu, MD PhD, Tomoko Yasuhiro, Kohei Tanaka, Toshio Yoshizawa, PhD, Weiguo Zhang, MD PhD, Jorge E. Cortes, MD, Michael Andreeff, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2642.
https://doi.org/10.1182/blood-2018-99-112211
Published: 2018
Journal Articles

IL15 Expressing CD123-Targeted Engager T-Cell Therapy for Adult Acute Myeloid Leukemia

Hong Mu, MD PhD, Huaxian Ma, MS, Abishek Vaidya, MS, Challice L. Bonifant, MD PhD, Stephen Gottschalk, MD, Mireya P. Velasquez, MD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2724.
https://doi.org/10.1182/blood-2018-99-116811
Published: 2018
Journal Articles

hnRNP K: A Regulator of Global Transcription and Translation That Drives Lymphomagenesis

Prerna Malaney, PhD, Miguel Gallardo, PhD, Marisa J Hornbaker, BS, Xiaorui Zhang, BS, Todd Link, PhD, Vrutant Shah, PhD, Sanzhar Alybayev, MS, Meng-Han Wu, Laura R Pageon, DVM, Huaxian Ma, MS, Rodrigo Jacamo, PhD, Li Yu, MD, Zijun Yidan Xu-Monette, PhD, Haley Steinman, BS, Hun Ju Lee, MD, Dos Sarbassov, PhD, Inmaculada Rapado, Michelle Barton, PhD, Joaquin Martinez-Lopez, MDPhD, Carlos E. Bueso-Ramos, MD PhD, Ken H. Young, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1346.
https://doi.org/10.1182/blood-2018-99-116163
Published: 2018