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Helena Sturesson
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Journal Articles

Unraveling How Treatment Shapes Clonal Evolution and Resistance in Murine KMT2A-Rearranged Leukemia with Subclonal Kras G12D

Ton Falques, Mattias Pilheden, Larissa Helena Moura-Castro, Qirui Zhang, Louise Ahlgren, Helena Sturesson, Kajsa Paulsson, Axel Hyrenius Wittsten, Anna K. Hagstroem-Andersson
Journal: Blood
Blood (2024) 144 (Supplement 1): 2769.
https://doi.org/10.1182/blood-2024-207772
Published: 2024
Journal Articles

The Relapse Mechanisms and Genomic Landscape Differ in KMT2A -r Pediatric Leukemia in Relation to Relapse Time

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Michael Walsh, Guangchun Song, Anders Castor, Cornelis Jan Pronk, Pauline Schneider, Ronald W. Stam, Gisela Barbany, Katja Pokrovskaja Tamm, Jonas Abrahamsson, Linda Fogelstrand, Olli Lohi, Jing Ma, Jinghui Zhang, Anna K. Hagstroem-Andersson
Journal: Blood
Blood (2023) 142 (Supplement 1): 2978.
https://doi.org/10.1182/blood-2023-185044
Published: 2023
Journal Articles

Unraveling Clonal Evolution and Mechanisms of Treatment Resistance in Murine KMT2A -Rearranged Leukemia with Subclonal FLT3 N676K

Ton Falques-Costa, Mattias Pilheden, Andrea Hanel, Qirui Zhang, Louise Ahlgren, Helena Sturesson, Lars Ronnstrand, Julhash Uddin Kazi, Merja Heinäniemi, Axel Hyrenius Wittsten, Anna K. Hagstroem-Andersson
Journal: Blood
Blood (2023) 142 (Supplement 1): 5918.
https://doi.org/10.1182/blood-2023-180636
Published: 2023
Journal Articles

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Anders Castor, Cornelis Jan Pronk, Gisela Barbany, Katja Pokrovskaja Tamm, Linda Fogelstrand, Michael P Walsh, Guangchun Song, Jinghui Zhang, Jing Ma, Anna Hagstroem-Andersson
Journal: Blood
Blood (2022) 140 (Supplement 1): 9189–9190.
https://doi.org/10.1182/blood-2022-165869
Published: 2022
Journal Articles

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

Mattias Pilheden, Ton Falqués, Louise Ahlgren, Helena Sturesson, Michael P Walsh, Guangchun Song, Anders Castor, Cornelis Pronk, Hanne Vibeke Marquart, Birgitte Lausen, Gisela Barbany, Katja Pokrovskaja Tamm, Ullrika Norén-Nyström, Linda Fogelstrand, Olli Lohi, Axel Hyrenius Wittsten, Jinghui Zhang, James R. Downing, Jing Ma, Anna Hagstroem-Andersson
Journal: Blood
Blood (2021) 138 (Supplement 1): 3479.
https://doi.org/10.1182/blood-2021-152082
Published: 2021
Journal Articles

Treatment Shapes Clonal Evolution and Resistance Patterns in Murine KMT2A -Rearranged Leukemia with Subclonal FLT3 N676K

Ton Falqués, Mattias Pilheden, Qirui Zhang, Louise Ahlgren, Helena Sturesson, Lars Ronnstrand, Axel Hyrenius Wittsten, Julhash U. Kazi, Anna Hagstroem-Andersson
Journal: Blood
Blood (2021) 138 (Supplement 1): 3354.
https://doi.org/10.1182/blood-2021-144760
Published: 2021
Journal Articles

FLT3 N676K drives Myeloid Leukemia in a Xenograft Model of KMT2A-MLLT3 leukemogenesis

Axel Hyrenius Wittsten, MSc, Mattias Pilheden, MSc, Jian Liu, PhD, Helena Ågerstam, PhD, Helena Sturesson, PhD, Anna K. Andersson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2499.
https://doi.org/10.1182/blood.V130.Suppl_1.2499.2499
Published: 2017
Journal Articles

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Mattias Pilheden, MSc, Axel Hyrenius Wittsten, MSc, Veronica Gonzalez-Pena, PhD, Helena Sturesson, PhD, Michael P Walsh, PhD, Guangchun Song, PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Lausen, MD PhD, Anders Castor, MD PhD, Jinghui Zhang, PhD, James R. Downing, MD, Jing Ma, PhD, Charles Gawad, MD PhD, Anna K. Andersson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2709.
https://doi.org/10.1182/blood.V130.Suppl_1.2709.2709
Published: 2017
Journal Articles

Activating Mutations Are Potent Pro-Leukemic Mediators in Murine MLL-MLLT3 Leukemia That Cause Distinct Transcriptional Profiles

Axel Hyrenius-Wittsten, MSc, Helena Sturesson, PhD, Michael P. Walsh, PhD, Jenny Hansson, PhD, Julhash U. Kazi, PhD, Mattias Pilheden, MSc, Stephanie Nance, Pankaj Gupta, Guangchun Song, PhD, Jinghui Zhang, PhD, Jing Ma, PhD, Tanja A. Gruber, MD PhD, James R. Downing, MD PhD, Anna K. Andersson, PhD
Journal: Blood
Blood (2016) 128 (22): 3918.
https://doi.org/10.1182/blood.V128.22.3918.3918
Published: 2016