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Journal Articles

Suppression of Multiple Myeloma Via Inhibition of EFNB2 Reverse Signaling

Joshua P. Sasine, Jennifer Dukov, Dana Tran, Heather A Himburg, Natalia Kozlova, Michelle Li, Jenny Kan, Mary Sehl, Gary J. Schiller, Ritchie Ho, Brijesh Singh, Bryanna Reinhardt, Peibin Yue, Christina Termini, Elena Pasquale, John P. Chute

Blood (2022) 140 (Supplement 1): 4251–4252.

https://doi.org/10.1182/blood-2022-165357

Published: 2022

Journal Articles

Epidermal growth factor receptor–dependent DNA repair promotes murine and human hematopoietic regeneration

Tiancheng Fang, Yurun Zhang, Vivian Y. Chang, Martina Roos, Christina M. Termini, Lia Signaevskaia, Mamle Quarmyne, Paulina K. Lin, Amara Pang, Jenny Kan, Xiao Yan, Anna Javier, Katherine Pohl, Liman Zhao, Peter Scott, Heather A. Himburg, John P. Chute

Blood (2020) 136 (4): 441–454.

https://doi.org/10.1182/blood.2020005895

Published: 2020

Includes: Supplemental data

Journal Articles

Epidermal Growth Factor Rejuvenates Aging Hematopoietic Stem Cells

Vivian Y. Chang, MD, M.S., Tiancheng Fang, Katherine A. Pohl, B.S., Evelyn Tran, B.A., Heather A Himburg, PhD, John P Chute, MD

Blood (2018) 132 (Supplement 1): 1284.

https://doi.org/10.1182/blood-2018-99-119929

Published: 2018

Journal Articles

Inhibition of Semaphorin 3A Signaling Promotes Regeneration of Hematopoietic Stem Cells and Their Bone Marrow Vascular Niche

John P Chute, MD, Christina Termini, PhDBS, Lauren Schlussel, Martina M Roos, PhDPharmD, Jenny Kan, BS, Joshua Sasine, MD, Tiancheng Fang, Heather A Himburg, PhD

Blood (2018) 132 (Supplement 1): 1292.

https://doi.org/10.1182/blood-2018-99-118790

Published: 2018

Journal Articles

Epidermal Growth Factor Receptor - Mediated DNA Repair Regulates Hematopoietic Stem Cell Regeneration

Tiancheng Fang, Heather A Himburg, PhD, Martina M Roos, PhDPharmD, Yurun Zhang, Jenny Kan, BS, Liman Zhao, John P Chute, MD

Blood (2018) 132 (Supplement 1): 638.

https://doi.org/10.1182/blood-2018-99-115526

Published: 2018

Journal Articles

Deletion of Pleiotrophin in LepR + Perivascular Cells Depletes Hematopoietic Stem Cells

Heather A Himburg, PhD, Vivian Y. Chang, MDMS, Joshua Sasine, MD, Jenny Kan, BS, Liman Zhao, John P. Chute, MD

Blood (2016) 128 (22): 1491.

https://doi.org/10.1182/blood.V128.22.1491.1491

Published: 2016

Journal Articles

A Small Molecule Inhibitor of Protein Tyrosine Phosphatase-Sigma (PTPσ) Promotes Hematopoietic Stem Cell (HSC) Regeneration

Yurun Zhang, Mamle Quarmyne, PhD, Heather A Himburg, PhD, Xiao Yan, William McBride, PhD, Michael Jung, PhD, John P. Chute, MD

Blood (2016) 128 (22): 822.

https://doi.org/10.1182/blood.V128.22.822.822

Published: 2016

Journal Articles

Dickkopf 1 (Dkk1) Regulates Hematopoietic Stem Cell Regeneration

Heather A Himburg, PhD, Phuong L Doan, MD, Xiao Yan, Mamle Quarmyne, PhD, Liman Zhao, Evelyn Tran, Nelson J. Chao, MD, Jeffrey Harris, PhD, John P Chute, MD

Blood (2015) 126 (23): 1200.

https://doi.org/10.1182/blood.V126.23.1200.1200

Published: 2015

Journal Articles

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell (HSC) Self-Renewal Via Control of mTOR Signaling

Xiao Yan, Heather A Himburg, PhD, Phuong L Doan, MD, Mamle Quarmyne, PhD, Evelyn Tran, Liman Zhao, Nelson J. Chao, MD, John P Chute, MD

Blood (2015) 126 (23): 1160.

https://doi.org/10.1182/blood.V126.23.1160.1160

Published: 2015

Journal Articles

Deletion of Pleiotrophin (PTN), a Vascular Niche Paracrine Factor, Abrogates Chronic Myeloid Leukemia Pathogenesis In Vivo

Heather A Himburg, PhD, Liman Zhao, John P Chute, MD

Blood (2015) 126 (23): 4268.

https://doi.org/10.1182/blood.V126.23.4268.4268

Published: 2015

Journal Articles

Protein Tyrosine Phosphatase-Sigma (PTPσ) Regulates Hematopoietic Stem Cell Repopulating Capacity

Mamle Quarmyne, Phuong L. Doan, MD, Heather A. Himburg, PhD, Xiao Yan, Liman Zhao, Nelson J. Chao, MD, John P. Chute, MD

Blood (2014) 124 (21): 4309.

https://doi.org/10.1182/blood.V124.21.4309.4309

Published: 2014

Journal Articles

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell Renewal

Xiao Yan, Heather A. Himburg, PhD, Phuong L. Doan, MD, Mamle Quarmyne, Nelson J. Chao, MD, John P. Chute, MD

Blood (2014) 124 (21): 248.

https://doi.org/10.1182/blood.V124.21.248.248

Published: 2014

Journal Articles

Pleiotrophin Improves Survival Following Radiation-Induced Myelosuppression and Mediates HSC Expansion Via Induction Of Ras Signaling

Heather A Himburg, PhD, Phuong L. Doan, MD, Mamle Quarmyne, Mai Nakamura, Nelson J. Chao, MD, John P. Chute, MD

Blood (2013) 122 (21): 1205.

https://doi.org/10.1182/blood.V122.21.1205.1205

Published: 2013

Journal Articles

Imatinib tackles lymphoma via the PDGFRβ + pericyte

John P. Chute, Heather A. Himburg

Blood (2013) 121 (26): 5107–5108.

https://doi.org/10.1182/blood-2013-05-501205

Published: 2013

Journal Articles

Facilitation of Hematopoietic Reconstitution Via Inhibition of Bone Marrow Endothelial Cell-Mediated SDF-1 Signaling.

Phuong L. Doan, MD, J. Lauren Russell, Heather A. Himburg, PhD, Sarah K. Meadows, Pamela Daher, Katherine Helms, Mamle Quarmyne, Jeffrey R. Harris, PhD, Tannishtha Reya, PhD, Nelson J. Chao, MD, David G. Kirsch, MD, PhD, John P. Chute, MD

Blood (2010) 116 (21): 3859.

https://doi.org/10.1182/blood.V116.21.3859.3859

Published: 2010

Journal Articles

VE Cadherin Positive Endothelial Cells Regulate Hematopoietic Reconstitution In Vivo.

J. Lauren Russell, Phuong Doan, MD, Heather A Himburg, PhD, Sarah K. Meadows, Pamela Daher, Katherine Helms, Mamle Quarmyne, Nelson J. Chao, MD, David Kirsch, MD, PhD, John P. Chute, MD

Blood (2010) 116 (21): 3734.

https://doi.org/10.1182/blood.V116.21.3734.3734

Published: 2010

Journal Articles

Pleiotrophin Signaling Is Necessary and Sufficient for Hematopoietic Stem Cell Self-Renewal In Vivo

Heather A Himburg, PhD, Pamela Daher, J. Lauren Russell, Phuong Doan, MD, Mamle Quarmyne, Sarah K. Meadows, Katherine Helms, Gonzalo Herradon, PhD, Nelson J. Chao, MD, John P. Chute, MD

Blood (2010) 116 (21): 404.

https://doi.org/10.1182/blood.V116.21.404.404

Published: 2010

Journal Articles

Systemic Administration of Pleiotrophin Induces Hematopoietic Stem Cell Regeneration In Vivo.

Heather A Himburg, PhD, Pamela Daher, Sarah Kristen Meadows, BS, J. Lauren Russell, Phuong Doan, MD, Garrett Muramoto, BS, Nelson J. Chao, MD, John Chute, MD

Blood (2009) 114 (22): 1498.

https://doi.org/10.1182/blood.V114.22.1498.1498

Published: 2009

Journal Articles

Tie2+ Bone Marrow Endothelial Cells Regulate Hematopoietic Reconstitution In Vivo.

Phuong L. Doan, MD, J. Lauren Russell, Sarah K. Meadows, Heather A Himburg, PhD, Pamela Daher, Nelson J. Chao, MD, David G. Kirsch, MD, PhD, John P. Chute, MD

Blood (2009) 114 (22): 248.

https://doi.org/10.1182/blood.V114.22.248.248

Published: 2009

Journal Articles

Deletion of Bak and Bax in Tie2+ BM Hematopoietic Stem Cells Induces a B Cell Lymphoproliferative Disorder.

Phuong L. Doan, MD, J. Lauren Russell, Sarah K. Meadows, Heather A. Himburg, PhD, Pamela Daher, Nelson J. Chao, MD, David G. Kirsch, MD, PhD, John P. Chute, MD

Blood (2009) 114 (22): 1247.

https://doi.org/10.1182/blood.V114.22.1247.1247

Published: 2009

NARROW

Suppression of Multiple Myeloma Via Inhibition of EFNB2 Reverse Signaling

Epidermal growth factor receptor–dependent DNA repair promotes murine and human hematopoietic regeneration

Epidermal Growth Factor Rejuvenates Aging Hematopoietic Stem Cells

Inhibition of Semaphorin 3A Signaling Promotes Regeneration of Hematopoietic Stem Cells and Their Bone Marrow Vascular Niche

Epidermal Growth Factor Receptor - Mediated DNA Repair Regulates Hematopoietic Stem Cell Regeneration

Deletion of Pleiotrophin in LepR + Perivascular Cells Depletes Hematopoietic Stem Cells

A Small Molecule Inhibitor of Protein Tyrosine Phosphatase-Sigma (PTPσ) Promotes Hematopoietic Stem Cell (HSC) Regeneration

Dickkopf 1 (Dkk1) Regulates Hematopoietic Stem Cell Regeneration

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell (HSC) Self-Renewal Via Control of mTOR Signaling

Deletion of Pleiotrophin (PTN), a Vascular Niche Paracrine Factor, Abrogates Chronic Myeloid Leukemia Pathogenesis In Vivo

Protein Tyrosine Phosphatase-Sigma (PTPσ) Regulates Hematopoietic Stem Cell Repopulating Capacity

Growth Factor Receptor-Bound Protein 10 (Grb10) Regulates Hematopoietic Stem Cell Renewal

Pleiotrophin Improves Survival Following Radiation-Induced Myelosuppression and Mediates HSC Expansion Via Induction Of Ras Signaling

Imatinib tackles lymphoma via the PDGFRβ + pericyte

Facilitation of Hematopoietic Reconstitution Via Inhibition of Bone Marrow Endothelial Cell-Mediated SDF-1 Signaling.

VE Cadherin Positive Endothelial Cells Regulate Hematopoietic Reconstitution In Vivo.

Pleiotrophin Signaling Is Necessary and Sufficient for Hematopoietic Stem Cell Self-Renewal In Vivo

Systemic Administration of Pleiotrophin Induces Hematopoietic Stem Cell Regeneration In Vivo.

Tie2+ Bone Marrow Endothelial Cells Regulate Hematopoietic Reconstitution In Vivo.

Deletion of Bak and Bax in Tie2+ BM Hematopoietic Stem Cells Induces a B Cell Lymphoproliferative Disorder.

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American Society of Hematology

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American Society of Hematology

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