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Hassan Yousaf
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Journal Articles

Drug Resistance Alters CD38 Expression and in Vitro Response to Daratumumab in Waldenstrom Macroglobulinemia Cells

Aneel Paulus, MD, Sharoon Akhtar, MPhil, Yamima Bashir, MBBS, Shumail M. Paulus, MBBS, Hassan Yousaf, Vivek Roy, MD, Sikander Ailawadhi, MD, Stephen Ansell, MD PhD, Thomas E. Witzig, MD, Asher A. Chanan-Khan, MD
Journal: Blood
Blood (2016) 128 (22): 3018.
https://doi.org/10.1182/blood.V128.22.3018.3018
Published: 2016
Journal Articles

Induction of Resistance to Proteasome Inhibition Preferentially Switches Survival Dependence from Bcl-2 to XIAP in Preclinical Models of Waldenstrom Macroglobulinemia: Pre-Clinical Rationale for Early Clinical Sequencing of ABT199

Sharoon Akhtar, MPhil, Aneel Paulus, MDMS, Kelara Samuel, Hassan Yousaf, Davitte Cogen, Vivek Roy, MD, Taimur Sher, MD, James M. Foran, MD, Candido E. Rivera, MD, Gerardo Colon-Otero, MD, Sikander Ailawadhi, MD, Asher Alban Chanan-Khan, MD
Journal: Blood
Blood (2015) 126 (23): 4839.
https://doi.org/10.1182/blood.V126.23.4839.4839
Published: 2015
Journal Articles

VLX1570, a First in Class Dub Inhibitor, Modulates BCR Signaling and CXCR4 Expression and Demonstrates Significant In Vivo Antitumor Activity in a Murine Model of Human Waldenstrom Macroglobulinemia

Aneel Paulus, MDMS, Sharoon Akhtar, MPhil, Kelara Samuel, Hassan Yousaf, Davitte Cogen, Jennifer Jiang, Abhisek Swaika, MBBS, Anne Novak, PhD, Stephen M Ansell, MD, PhD, Morie A Gertz, MD, Robert A. Kyle, MD, Thomas E. Witzig, MD, George J Weiner, MD, Peter Martin, MD, Morton Coleman, MD, Sikander Ailawadhi, MD, Joachim Gullbo, MD PhD, Stig Linder, PhD, Geraldo Otero-Colon, Vivek Roy, MD, Kasyapa S. Chitta, PhD, Asher Alban Chanan-Khan, MD
Journal: Blood
Blood (2015) 126 (23): 703.
https://doi.org/10.1182/blood.V126.23.703.703
Published: 2015
Journal Articles

Aurora Kinase Is a Therapeutic Target in Ibrutinib-Resistant Waldenstrom Macroglobulinemia: In-Silico Target Identification and in-Vitro Validation

Aneel Paulus, MDMS, Kasyapa S. Chitta, PhD, Sharoon Akhtar, MPhil, Hassan Yousaf, Davitte Cogen, Shireen Vali, Ansu Kumar, Neeraj Kumar Singh, Taher Abbasi, James M. Foran, MD, Candido E. Rivera, MD, Taimur Sher, MD, Vivek Roy, MD, Sikander Ailawadhi, MD, Asher Alban Chanan-Khan, MD
Journal: Blood
Blood (2015) 126 (23): 2754.
https://doi.org/10.1182/blood.V126.23.2754.2754
Published: 2015
Journal Articles

Identification of USP14 and UCHL5 As Druggable Oncotargets in Ibrutinib-Resistant Mantle Cell Lymphoma

Aneel Paulus, MDMS, Sharoon Akhtar, MPhil, Kelara Samuel, Hassan Yousaf, Davitte Cogen, Pooja Advani, MBBS, Thomas E. Witzig, MD, George J Weiner, MD, Sikander Ailawadhi, MD, Joachim Gullbo, MD PhD, Stig Linder, PhD, Geraldo Otero-Colon, Kasyapa S. Chitta, PhD, Asher Alban Chanan-Khan, MD
Journal: Blood
Blood (2015) 126 (23): 1557.
https://doi.org/10.1182/blood.V126.23.1557.1557
Published: 2015