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Hans-Ulrich Klein, PhD
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Journal Articles

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Chantana Polprasert, MD, Isabell Schulze, Mikkael A. Sekeres, MD MS, Hideki Makishima, MD PhD, Bartlomiej P Przychodzen, Naoko Hosono, MD PhD, Jarnail Singh, PhD, Richard A Padgett, PhD, Xiaorong Gu, PhD, Eckhard Jankowsky, PhD, Michael Clemente, MS, Brittney Dienes, Sudipto Mukherjee, MD MPH, Utz Krug, MD, Hans-Ulrich Klein, PhD, Martin Dugas, MD, Wolfgang E Berdel, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Carsten Müller-Tidow, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2014) 124 (21): 125.
https://doi.org/10.1182/blood.V124.21.125.125
Published: 2014
Journal Articles

Identification of CAR As a Novel Mediator of Erythroid Differentiation and Migration That Is Specifically Downregulated in Erythropoietic Progenitor Cells in Patients with MDS

Karin Bauer, PhD, Sigrid Machherndl-Spandl, MD, Susanne Suessner, MSc, Martin Danzer, MSc, Johannes Pröll, PhD, Jeroen Lauf, Gregor Eisenwort, MD PhD, Wolfgang R. Sperr, MD, Hans-Ulrich Klein, PhD, Gregor Hoermann, MD PhD, Norman Häfner, PhD, Marie Bene, PharmSciD, PhD, Uwe Platzbecker, MD, Ansgar Weltermann, MD, Christian Gabriel, MD, Ulrich Germing, Peter Bettelheim, MD, Peter Valent, MD
Journal: Blood
Blood (2014) 124 (21): 1570.
https://doi.org/10.1182/blood.V124.21.1570.1570
Published: 2014
Journal Articles

Abnormal Expression Of The Major Coxsackie-Adenovirus Receptor CAR On Immature Dysplastic CD105+ Erythroid Progenitor Cells In Patients With MDS and Related Bone Marrow Neoplasms

Sigrid Machherndl-Spandl, MD, Susanne Suessner, Martin Danzer, Johannes Proell, Christian Gabriel, MD, Jeroen Lauf, Gregor Eisenwort, Wolfgang R Sperr, M.D., Peter Valent, Hans-Ulrich Klein, PhD, Marie-Christine Bene, PharmSciD, PhD, Ulrich Germing, MD, Uwe Platzbecker, MD, PhD, Ansgar Weltermann, MD, Otto Zach, PhD, Peter Bettelheim, MD
Journal: Blood
Blood (2013) 122 (21): 2818.
https://doi.org/10.1182/blood.V122.21.2818.2818
Published: 2013
Journal Articles

Exome Sequencing Of Paired Chronic-Blast Phase Samples In Myeloproliferative Neoplasms Reveals High Frequency Of Rare Germline Sequence Variants In TYK2 and Novel Blast Phase-Restricted Mutations

Nils H. Thoennissen, MD, Isabell Schulze, Terra L Lasho, MT, (ASCP), Georg Evers, MD, Gabriela B. Thoennissen, MD, Hans-Ulrich Klein, PhD, Martin Dugas, PhD, Wolfgang E. Berdel, MD, Carsten Müller-Tidow, MD, Animesh Pardanani, MBBS, PhD, Ayalew Tefferi, MD
Journal: Blood
Blood (2013) 122 (21): 2849.
https://doi.org/10.1182/blood.V122.21.2849.2849
Published: 2013
Journal Articles

Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

Yasunobu Nagata, MD, Vera Grossmann, PhD, Yusuke Okuno, Ulrike Bacher, MD, Genta Nagae, M.D., Ph.D., Susanne Schnittger, PhD, Yusuke Shiozawa, MD, Ayana Kon, MD, Tamara Alpermann, Kenichi Yoshida, MD, Masashi Sanada, MD, Andreas Roller, PhD, Niroshan Nadarajah, MSc, Yuichi Shiraishi, PhD, H. Phillip Koeffler, MD, PhD, Hans-Ulrich Klein, PhD, Martin Dugas, MD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Alexander Kohlmann, PhD, Satoru Miyano, PhD, Claudia Haferlach, MD, Hiroyuki Aburatani, M.D., Ph.D., Wolfgang Kern, MD, Seishi Ogawa, MD, PhD, Torsten Haferlach, MD
Journal: Blood
Blood (2013) 122 (21): 521.
https://doi.org/10.1182/blood.V122.21.521.521
Published: 2013
Journal Articles

Identification of the PML-RARα Associated DNA Methylome Using Reduced Representation Bisulfite Sequencing in Primary Patient Samples

Christian Rohde, PhD, Till Schoofs, Katja Hebestreit, Hans-Ulrich Klein, PhD, Anika Witten, PhD, Monika Stoll, PhD, Eva Lengfelder, MD, Wolf-Karsten Hofmann, MD, Peter Schlenke, PhD, Stefanie Göllner, PhD, Thomas Büchner, MD, Maria Cristina Sauerland, Steffen Koschmieder, MD, Wolfgang E. Berdel, Martin Dugas, MD, Carsten Müller-Tidow, MD
Journal: Blood
Blood (2011) 118 (21): 2436.
https://doi.org/10.1182/blood.V118.21.2436.2436
Published: 2011
Journal Articles

EZH2 Mutations Can Be Detected in 23% of t(10;11)(p13;q14)/ PICALM-MLLT10 Positive Acute Leukemias,

Vera Grossmann, MSc, Ulrike Bacher, MD, Valentina Artusi, MSc, Hans-Ulrich Klein, PhD, Wolfgang Kern, MD, Susanne Schnittger, PhD, Torsten Haferlach, MD, Alexander Kohlmann, PhD, Claudia Haferlach, MD
Journal: Blood
Blood (2011) 118 (21): 3440.
https://doi.org/10.1182/blood.V118.21.3440.3440
Published: 2011
Journal Articles

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

Tino Schenk, PhD, Stefanie Göllner, PhD, Weihsu Claire Chen, PhD, Louise Howell, BSc, Liqing Jin, MD, Katja Hebestreit, Hans-Ulrich Klein, PhD, Alan K Burnett, MD, Ken I. Mills, PhD, FRCPath, Laurence Marton, MD, Robert Casero, Jr., PhD, Patrick Woster, PhD, Martin Dugas, MD, Jean C.Y. Wang, MD, PhD, John E. Dick, PhD, Carsten Müller-Tidow, MD, Kevin Petrie, PhD, Arthur Zelent, PhD
Journal: Blood
Blood (2011) 118 (21): 224.
https://doi.org/10.1182/blood.V118.21.224.224
Published: 2011
Journal Articles

Whole Genome Amplification with Subsequent High Throughput Sequencing Allows Comprehensive Genome-Wide Analysis of Single Leukemic Cells

Vera Binder, MD, Christoph Bartenhagen, Vera Okpanyi, PhD, Bianca Behrens, Birte Moehlendick, PhD, Hans-Ulrich Klein, PhD, Harald Rieder, MD, Michael Gombert, PhD, Martin Dugas, MD, Nikolas Hendrik Stoecklein, MD, Arndt Borkhardt, MD
Journal: Blood
Blood (2011) 118 (21): 1437.
https://doi.org/10.1182/blood.V118.21.1437.1437
Published: 2011