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Journal Articles

A Novel Monoclonal Antibody Combination Plus DC/AML Fusion Vaccine Eradicates AML in an Immunocompetent Murine Model

Dina Stroopinsky, PhD, Jessica Liegel, MD, Kathleen M. Mahoney, MD PhD, Jacalyn Rosenblatt, MD, Benjamin L. Ebert, MD PhD, Richard M. Stone, MD, Maryam Rahimian, MD, Myrna Nahas, MD, Shira Orr, PhD, Marzia Capelletti, PhD MMSc, Matthew Weinstock, MD, Salvia Jain, MD, Lina Bisharat, MA, Haider Ghiasuddin, BA, Adam Morin, BA, Donald Kufe, MD, Gordon J Freeman, PhD, David E. Avigan, MD

Blood (2018) 132 (Supplement 1): 1446.

https://doi.org/10.1182/blood-2018-99-120259

Published: 2018

Journal Articles

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Nikolaos Patsoukis, PhD, Jonathan Duke-Cohan, PhD, Apoorvi Chaudhri, Eunyoung Park, PhD, Council Asia, Anders Berg, MD PhD, Gordon J Freeman, PhD, Michael Eck, Vassiliki A Boussiotis, MD PhD

Blood (2018) 132 (Supplement 1): 862.

https://doi.org/10.1182/blood-2018-99-117486

Published: 2018

Journal Articles

Integrated Genetic and Topological Analysis Reveals a Hodgkin-like Mechanism of Immune Escape in T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Blood (2018) 132 (Supplement 1): 1579.

https://doi.org/10.1182/blood-2018-99-118610

Published: 2018

Journal Articles

Interaction of Both SH2 Domains of SHP-2 with a PD-1 Homodimer Is Required for PD-1-Mediated Inhibition of T Cell Responses

Nikolaos Patsoukis, PhD, Asia Council, Anders Berg, MD PhD, Kankana Bardhan, PhD, Jessica D Weaver, PhD, Kathleen M. Mahoney, MD PhD, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD PhD

Blood (2016) 128 (22): 859.

https://doi.org/10.1182/blood.V128.22.859.859

Published: 2016

Journal Articles

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Blood (2015) 126 (23): 147.

https://doi.org/10.1182/blood.V126.23.147.147

Published: 2015

Journal Articles

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

Bruce R. Blazar, MD, Roddy S. O'Connor, PhD, Michael C. Milone, MD PhD, Michael L. Dustin, PhD, James L. Riley, PhD, Benjamin G. Vincent, MD, Jonathan S. Serody, MD, Ryan P Flynn, PhD, Katelyn Paz, Jing Du, Angela Panoskaltsis-Mortari, PhD, Miller Jeffrey, MD, Rafi Ahmed, PhD, Laurence A. A. Turka, MD, Gordon J. Freeman, PhD, Arlene H. Sharpe, MDPhD, Asim Saha, PhD

Blood (2015) 126 (23): SCI-8.

https://doi.org/10.1182/blood.V126.23.SCI-8.SCI-8

Published: 2015

Journal Articles

PD-1 Inhibits TCR Proximal Signaling By Sequestering SHP-2 Phosphatase and Facilitating Csk-Mediated Inhibitory Phosphorylation of Lck

Kankana Bardhan, PhD, Nikolaos Patsoukis, PhD, Duygu Sari, Theodore Anagnostou, Pranam Chatterjee, Gordon J. Freeman, PhD, Lequn Li, MD PhD, Vassiliki A. Boussiotis, MD PhD

Blood (2015) 126 (23): 283.

https://doi.org/10.1182/blood.V126.23.283.283

Published: 2015

Journal Articles

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

Blood (2014) 124 (21): 74.

https://doi.org/10.1182/blood.V124.21.74.74

Published: 2014

Journal Articles

JAK1 and JAK2 Modulate Tumor Cell Susceptibility To Natural Killer (NK) Cells Through Regulation Of PDL1 Expression

Roberto Bellucci, PhD, Allison Martin, BS, Davide Bommarito, Kathy S. Wang, PhD, Gordon J Freeman, PhD, Jerome Ritz, MD

Blood (2013) 122 (21): 3472.

https://doi.org/10.1182/blood.V122.21.3472.3472

Published: 2013

Journal Articles

Distinct Roles Of PD-1 Itsm and ITIM In Regulating Interactions With SHP-2, ZAP-70 and Lck, and PD-1-Mediated Inhibitory Function

Pranam Chatterjee, Nikolaos Patsoukis, PhD, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2013) 122 (21): 191.

https://doi.org/10.1182/blood.V122.21.191.191

Published: 2013

Journal Articles

Ex Vivo Expansion of Donor-Derived Anti-Tumor T Cells for CLL-Specific Adoptive Immunotherapy

Masayasu Naito, MD, PhD, Ursula Hainz, PhD, Kristen Stevenson, Anselmo Alonso, Ken-ichi Matsuoka, MD, PhD, Tesuro Sasada, MD, PhD, Donna Neuberg, ScD, Jerome Ritz, MD, Gordon J. Freeman, PhD, Catherine J Wu, MD

Blood (2011) 118 (21): 978.

https://doi.org/10.1182/blood.V118.21.978.978

Published: 2011

Journal Articles

Integrative Genomic Analysis of HIV-Specific CD8 + T Cells Reveals That PD-1 Inhibits T Cell Function by Upregulating the AP-1 Transcription Factor BATF.

Michael Quigley, Ph.D., Florencia Pereyra, M.D., Bjorn Nilsson, M.D., Ph.D., Quentin Eichbaum, M.D., Ph.D., MPH, Boris Julg, M.D., Jonathan Jesneck, Ph.D., Kathleen Brosnahan, Kate Russell, Ildiko Toth, Ph.D., Alicja Piechocka-Trocha, D.V.M, Haina Shin, Gordon J Freeman, PhD, E. John Wherry, Ph.D., Bruce D Walker, M.D., Benjamin L. Ebert, MD, DPhil, W. Nicholas Haining, B.M., B.Ch.

Blood (2009) 114 (22): 916.

https://doi.org/10.1182/blood.V114.22.916.916

Published: 2009

Journal Articles

Peripheral Alloantigen Drives Early Dysfunction and Eventual Exhaustion of CTL Following Delayed Donor Leukocyte Infusions.

Barry R Flutter, PhD, Farnaz Fallah-Arani, PhD, Clare Bennett, PhD, Janani Sivakumaran, Gordon J Freeman, PhD, Megan Sykes, MD, PhD, Ronjon Chakraverty, MD, PhD

Blood (2008) 112 (11): 2346.

https://doi.org/10.1182/blood.V112.11.2346.2346

Published: 2008

Journal Articles

Twisted Gastrulation (Tsg), an Evolutionarily Conserved, Secreted, Morphogenetic Protein Enhances TGF-b Signaling in T Lymphocytes.

Dimitrios Tzachanis, MD, PhD, Esther M. Lafuente, PhD, Lequn Li, MD, PhD, Alla Berezovskaya, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2005) 106 (11): 341.

https://doi.org/10.1182/blood.V106.11.341.341

Published: 2005

Journal Articles

Rap1-GTP Promotes the Generation of Regulatory T Cells in Vivo.

Lequn Li, MD, PhD, Rebecca Greenwald, PhD, Esther M. Lafuente, PhD, Dimitrios Tzachanis, MD, PhD, Alla Berezovskaya, Gordon J. Freeman, PhD, Arlene H. Sharpe, MD, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2004) 104 (11): 110.

https://doi.org/10.1182/blood.V104.11.110.110

Published: 2004

Journal Articles

The E3 Ubiquitin Ligase TRIM36, a Transcriptional Target of Tob, Is Expressed in Anergic T Cells and Mediates Unresponsiveness through Proteolysis of Signaling Proteins PLC- γ1 and PKC-𝛉.

Dimitrios Tzachanis, MD, PhD, Alla Berezovskaya, Esther M. Lafuente, PhD, Lequn Li, MD, PhD, Gordon J. Freeman, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2004) 104 (11): 113.

https://doi.org/10.1182/blood.V104.11.113.113

Published: 2004

NARROW

A Novel Monoclonal Antibody Combination Plus DC/AML Fusion Vaccine Eradicates AML in an Immunocompetent Murine Model

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Integrated Genetic and Topological Analysis Reveals a Hodgkin-like Mechanism of Immune Escape in T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Interaction of Both SH2 Domains of SHP-2 with a PD-1 Homodimer Is Required for PD-1-Mediated Inhibition of T Cell Responses

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

PD-1 Inhibits TCR Proximal Signaling By Sequestering SHP-2 Phosphatase and Facilitating Csk-Mediated Inhibitory Phosphorylation of Lck

Actionable Genetic Features of Primary Testicular and Primary Central Nervous System Lymphomas

JAK1 and JAK2 Modulate Tumor Cell Susceptibility To Natural Killer (NK) Cells Through Regulation Of PDL1 Expression

Distinct Roles Of PD-1 Itsm and ITIM In Regulating Interactions With SHP-2, ZAP-70 and Lck, and PD-1-Mediated Inhibitory Function

Ex Vivo Expansion of Donor-Derived Anti-Tumor T Cells for CLL-Specific Adoptive Immunotherapy

Integrative Genomic Analysis of HIV-Specific CD8 + T Cells Reveals That PD-1 Inhibits T Cell Function by Upregulating the AP-1 Transcription Factor BATF.

Peripheral Alloantigen Drives Early Dysfunction and Eventual Exhaustion of CTL Following Delayed Donor Leukocyte Infusions.

Twisted Gastrulation (Tsg), an Evolutionarily Conserved, Secreted, Morphogenetic Protein Enhances TGF-b Signaling in T Lymphocytes.

Rap1-GTP Promotes the Generation of Regulatory T Cells in Vivo.

The E3 Ubiquitin Ligase TRIM36, a Transcriptional Target of Tob, Is Expressed in Anergic T Cells and Mediates Unresponsiveness through Proteolysis of Signaling Proteins PLC- γ1 and PKC-𝛉.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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