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George Q Daley, MD PhD
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Journal Articles

An Essential Role for the RNA Editor-Exonuclease Axis in Terminal Erythroid Differentiation

Areum Han, PhD, Alena V. Yermalovich, PhD, Vanessa Lundin, PhD, Daniel S. Pearson, MD PhD, Mariam Hachimi, PhD, Patricia Sousa, Brianna Hilton, Michael Morse, John Atwater, Yosra Zhang, Pheobe Hunter, Vivian Morris, Jihan K. Osborne, PhD, Jenna M. Frame, PhD, Ran Jing, PhD, Yu Chung Huang, MD, Caroline Kubaczka, PhD, Trista E. North, PhD, Thorsten Schlaeger, PhD, George Q. Daley, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3.
https://doi.org/10.1182/blood-2020-142757
Published: 2020
Journal Articles

Single Cell Resolution Mapping of Hematopoietic Stem and Progenitor Cell States throughout Human Life

Hojun Li, MD PhD, Vincent Butty, Guinevere Connelly, Vivian Morris, George Q. Daley, MD PhD, Jennifer Whangbo, MD PhD, Edroaldo Lummertz da rocha, PhD, Robert Grant Rowe, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
https://doi.org/10.1182/blood-2020-136380
Published: 2020
Journal Articles

Mechanisms of Leukemia Stem Cell Plasticity Revealed By Single Cell Analysis

R. Grant Rowe, George Q. Daley, MD PhD, Trista E. North, PhD, William Marion, Yana Pikman, MD, Marian H. Harris, MD PhD, Vivian Morris, Edroaldo Lummertz da rocha, PhD, Alex K. Shalek, PhD, Travis Hughes, Prerana Sensharma, Dahai Wang, Patricia Sousa, Shannan Ho Sui, Sergey Naumenko, Renan Vinicius Da Silva
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-135998
Published: 2020
Journal Articles

Ezh1 Inhibits Commitment to Hemogenic Fate and HSPC Formation during Vertebrate Development

Rebecca Soto, BS, Edroaldo Lummertz da rocha, PhD, Linda T Vo, PhD, Mariam Hachimi, PhD, Jenna M Frame, PhD, Paul J. Wrighton, PhD, Wolfram Goessling, MD PhD, George Q. Daley, MD PhD, Trista E North, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3710.
https://doi.org/10.1182/blood-2019-131464
Published: 2019
Journal Articles

Optimized Beta-Globin Expression and Enucleation from Induced Red Blood Cells for In Vitro Modeling of Sickle Cell Disease

Tolulope O Rosanwo, BA, Melissa Kinney, PhD, Martha A Clark, PhD, Linda T Vo, PhD, R. Grant Rowe, MD PhD, Natasha M. Archer, MD, Matthew M Heeney, MD, Thorsten Schlaeger, PhD, Daniel E. Bauer, MD PhD, Mark D. Fleming, MD DPhil, Manoj T Duraisingh, PhD, Stuart H. Orkin, MD, Carlo Brugnara, MD, Trista North, PhD, George Q. Daley, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2359.
https://doi.org/10.1182/blood-2018-99-114136
Published: 2018
Journal Articles

Novel Epigenetic Vulnerabilities for Diffuse Large B-Cell Lymphoma

Deepak Jha, PhD, George Q. Daley, MD PhD, Benoit Laurent, PhD, Cheng Zhang, PhD, Caroline Kubaczka, PhD, Bjoern Chapuy, MD PhD, Patricia Sousa, Pavlos Missios, MD PhD, R. Grant Rowe, MD PhD, Yu-Chung Huang, MD, Yang Tan, Jessica Barragan, Trista North, PhD, Thorsten Schlaeger, PhD, Hu Li, PhD, Yang Shi, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2600.
https://doi.org/10.1182/blood-2018-99-115030
Published: 2018
Journal Articles

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Jenna M Frame, PhD, Timothy Long, Caroline Schuster-Kubaczka, PhD, Virginie Esain, PhD, Sung Eun Lim, PhD, George Q. Daley, MD PhD, Trista North, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 330.
https://doi.org/10.1182/blood-2018-99-117076
Published: 2018
Journal Articles

Modeling Fanconi Anemia Using Human Induced Pluripotent Stem Cells By Reversible Complementation

R. Grant Rowe, MD PhD, William Marion, Sonya Ruiz-Torres, Edroaldo Lummertz da Rocha, Yosra Girvan, Thorsten Schlaeger, PhD, Trista E. North, PhD, Susanne Wells, George Q. Daley, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3856.
https://doi.org/10.1182/blood-2018-99-111701
Published: 2018
Journal Articles

Piezo1-Sensitive Biomechanical Pulsation Stimulates Long-Term Hematopoietic Stem Cell Formation

Giorgia Scapin, PhD, Jennifer Cillis, B.S., Taylor Patch, Priyanka R Dharampuriya, M.S., Elliott J. Hagedorn, PhD, Vanessa Lundin, Owen J Tamplin, PhD, Heidi Andeson, Leonard I. Zon, MD, George Q. Daley, MD PhD, Dhvanit I Shah, PhD PharmD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3826.
https://doi.org/10.1182/blood-2018-99-110265
Published: 2018
Journal Articles

Engineering of Induced Pluripotent Stem Cell-Derived Hemogenic Endothelium

Jerry Lee, MPhil, MS, Ryohichi Sugimura, MD PhD, George Q Daley, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2424.
https://doi.org/10.1182/blood.V130.Suppl_1.2424.2424
Published: 2017
Journal Articles

Interferon-Gamma Pathway Regulates Emergence of Engraftable Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells

Ryohichi Sugimura, MD PhD, Clara Soria Valles, George Q. Daley, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2426.
https://doi.org/10.1182/blood.V130.Suppl_1.2426.2426
Published: 2017
Journal Articles

A Bioreactor Simulating Pulse-Pressure Mediated Circumferential Stretch Stimulates Hematopoietic Stem Cell Formation

Giorgia Scapin, Jennifer Cillis, Liisa Kanninen, Taylor Patch, Vanessa Lundin, Elliott J. Hagedorn, PhD, Vikas Trivedi, Heidi Andeson, Leonard I. Zon, MD, George Q. Daley, MD PhD, Dhvanit I Shah, PhD PharmD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1142.
https://doi.org/10.1182/blood.V130.Suppl_1.1142.1142
Published: 2017
Journal Articles

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biophysical Forces of Blood Flow

Lindsay N. Theodore, BS, Vanessa Lundin, PhD, Paul J. Wrighton, PhD, Andrew G. Cox, PhD, Patricia Sousa, Wolfram Goessling, MD PhD, Donald E. Ingber, MD PhD, George Q. Daley, MD PhD, Trista E. North, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1147.
https://doi.org/10.1182/blood.V130.Suppl_1.1147.1147
Published: 2017
Journal Articles

Enucleation and Beta-Globin Expression in Induced Red Blood Cells: A Platform to Model Sickle Cell Anemia

Tolulope O Rosanwo, BA, Melissa Kinney, PhD, Linda T Vo, PhD, Vanessa Lundin, PhD, George Q. Daley, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 538.
https://doi.org/10.1182/blood.V130.Suppl_1.538.538
Published: 2017
Journal Articles

The Age of the Hematopoietic Microenvironment Specifies Lineage Commitment in MLL-Rearranged Leukemia

Grant Rowe, MD PhD, Edroaldo Lummertz da Rocha, Patricia Sousa, Pavlos Missios, Michael Morse, Jessica Barragan, Ronald Mathieu, George Q Daley, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 135.
https://doi.org/10.1182/blood.V130.Suppl_1.135.135
Published: 2017
Journal Articles

Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells

Melisa Ruiz-Gutierrez, MD PhD, Ozge Vargel Bolukbasi, PhD, Linda Vo, Ryohichi Sugimura, MD PhD, Marilyn Sanchez Bonilla, MS, Andriana Kotini, PhD, Carl D. Novina, MD PhD, George Q. Daley, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1496.
https://doi.org/10.1182/blood.V128.22.1496.1496
Published: 2016
Journal Articles

Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells Via Transcription Factor Conversion of Hemogenic Endothelium

Ryohichi Sugimura, MDPhD, Areum Han, PhD, Deepak Jha, PhD, Yi-Fen Lu, PhD, Jeremy A Goettel, PhD, Erik Serrao, PhD, Robert Grant Rowe, MD PhD, Irene Wong, Patricia Sousa, Andrea Ditadi, PhD, Gordon Keller, PhD, Alan Engelman, PhD, Scott Snapper, MD PhD, Sergei Doulatov, PhD, George Q. Daley, MD PhD
Journal: Blood
Blood (2016) 128 (22): 371.
https://doi.org/10.1182/blood.V128.22.371.371
Published: 2016
Journal Articles

MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma

Salomon Manier, MD, John Powers, PhD, Antonio Sacco, BS, Siobhan Glavey, MD, Daisy Huynh, BS, MS, Michaela R. Reagan, PhD, Karma Salem, MD, Michele Moschetta, MD, Yuji Mishima, PhD, Xavier Leleu, MD PhD, Aldo M Roccaro, MD PhD, George Q. Daley, MD PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2015) 126 (23): 1755.
https://doi.org/10.1182/blood.V126.23.1755.1755
Published: 2015
Journal Articles

Hematopoietic Stem Cells Develop in the Absence of Endothelial Cadherin 5 Expression

Heidi Anderson, Taylor Patch, Pavan Reddy, Elliott Hagedorn, Owen J. Tamplin, PhD, Daniel E. Bauer, MD, PhD, Barry H. Paw, MD, PhD, Dietmar Vestweber, Leonard I. Zon, MD, Stuart H. Orkin, MD, George Q. Daley, MD PhD, Dhvanit I. Shah, PhD
Journal: Blood
Blood (2015) 126 (23): 1165.
https://doi.org/10.1182/blood.V126.23.1165.1165
Published: 2015
Journal Articles

Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells

Sergei Doulatov, PhD, Linda T Vo, Elizabeth R Macari, PhD, Stephanie S Chou, Manav Gupta, Michelle Godfrey, Katherine McGrath, Thorsten M Schlaeger, PhD, Leonard I. Zon, MD, George Q. Daley, MD PhD
Journal: Blood
Blood (2014) 124 (21): 359.
https://doi.org/10.1182/blood.V124.21.359.359
Published: 2014