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Journal Articles

Rapid Engraftment, Immune Recovery, and Resolution of Transfusion Dependence in Treatment-Refractory Severe Aplastic Anemia Following Transplantation with Ex Vivo Expanded Umbilical Cord Blood (Omidubicel)

Mohamed Samour, MD, Georg Aue, MD PhD, Joseph Clara, Jennifer Wilder, Robert Reger, MS, Rosa Nadal Rios, MD, Kate Stringaris, MD PhD, Brian Wells, Lisa Cook, Kristen Gunn, Reem A Shalabi, PharmD, Josef Rivero, Patricia Prince, David F. Stroncek, MD, Willy A. Flegel, MD, Xin Tian, PhD, Richard W. Childs, MD

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-137771

Published: 2020

Journal Articles

Single Agent Ibrutinib (PCI-32765) Achieves Equally Good and Durable Responses In Chronic Lymphocytic Leukemia (CLL) Patients With and Without Deletion 17p

Mohammed Farooqui, DO, Georg Aue, MD, Janet Valdez, PA, Sabrina Martyr, MD, Jade Jones, Susan Soto, RN, Maryalice Stetler-Stevenson, MD, PhD, Constance Yuan, MD, PhD, Diane C Arthur, M.D., Francine Thomas, B.S., Xin Tian, PhD, Delong Liu, PhD, Irina Maric, MD, Adrian Wiestner, MD, PhD

Blood (2013) 122 (21): 673.

https://doi.org/10.1182/blood.V122.21.673.673

Published: 2013

Journal Articles

In Patients With Chronic Lymphocytic Leukemia (CLL) Ibrutinib Effectively Reduces Clonal IgM Paraproteins and Serum Free Light Chains While Increasing Normal IgM, IgA Serum Levels, Suggesting a Nascent Recovery Of Humoral Immunity

Georg Aue, MD, Mohammed Farooqui, DO, Jade Jones, Janet Valdez, PA, Sabrina E. Martyr, MD, Susan Soto, RN, Maryalice Stetler-Stevenson, MD, PhD, Constance Yuan, MD, PhD, Adrian Wiestner, MD, PhD

Blood (2013) 122 (21): 4182.

https://doi.org/10.1182/blood.V122.21.4182.4182

Published: 2013

Journal Articles

Ibrutinib (PCI 32765) Rapidly Improves Platelet Counts in Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (CLL/SLL) Patients and Has Minimal Effects On Platelet Aggregation

Mohammed Farooqui, DO, Jay Nelson Lozier, Janet Valdez, PA, Nakhle Saba, MD, Ajunae Wells, Susan Soto, RN, Delong Liu, Ph.D., Georg Aue, MD, Adrian Wiestner, MD, PhD

Blood (2012) 120 (21): 1789.

https://doi.org/10.1182/blood.V120.21.1789.1789

Published: 2012

Journal Articles

Phase I Study of On 01910.Na (rigosertib), a Multikinase PI3K Inhibitor in Relapsed/Refractory B-Cell Malignancies

Mark Roschewski, MD, Mohammed Farooqui, DO, Georg Aue, MD, Clifton C. Mo, MD, Janet Valdez, PA, Susan Soto, RN, Patricia Perez-Galan, PhD, Francois Wilhelm, MD, PhD., Adrian Wiestner, MD, PhD

Blood (2012) 120 (21): 1803.

https://doi.org/10.1182/blood.V120.21.1803.1803

Published: 2012

Journal Articles

In Vivo Effects of Ibrutinib On BCR Signaling, Tumor Cell Activation and Proliferation in Blood and Tissue-Resident Cells of Chronic Lymphocytic Leukemia Patients

Sarah E. M. Herman, PhD, Mohammed Farooqui, DO, Rahel Bezabhie, Georg Aue, MD, Adrian Wiestner, MD, PhD

Blood (2012) 120 (21): 185.

https://doi.org/10.1182/blood.V120.21.185.185

Published: 2012

Journal Articles

Rapid Decrease in Overall Tumor Burden On Ibrutinib (PCI-32765) in CLL Despite Transient Increase in ALC Indicates a Significant Degree of Treatment Induced Cell Death.

Mohammed Farooqui, DO, Georg Aue, MD, Janet Valdez, PA, Nakhle Saba, MD, Sarah E. M. Herman, PhD, Andrew Lipsky, MS IV, Leodayan Bojanowski, DNP, CIP, RN, Ajunae Wells, Susan Soto, RN, Delong Liu, Ph.D., Adrian Wiestner, MD, PhD

Blood (2012) 120 (21): 2899.

https://doi.org/10.1182/blood.V120.21.2899.2899

Published: 2012

Journal Articles

Increased Incidence of Thrombosis with Lenalidomide in Chronic Lymphocytic Leukemia: Effect of Lenalidomide On Inflammation, Endothelial Cell Damage and Coagulation.

Georg Aue, MD, Jay Nelson Lozier, MD, PhD, Ann Marie Cullinane, Federica Gibellini, PhD, Xin Tian, Ph.D., Leigh Samsel, Philip McCoy, PHD, Adrian Wiestner, MD, PhD

Blood (2009) 114 (22): 455.

https://doi.org/10.1182/blood.V114.22.455.455

Published: 2009

Journal Articles

Sox4 Downregulates Pu.1 Gene Expression by Binding to An Upper Regulatory Element of Pu.1, a Mechanism Contributing to Leukemogenesis.

Georg Aue, MD, Yang Du, PhD, Susan Cleveland, Stephen Smith, Utpal P. Dave, MD, Nancy Jenkins, PhD., Neal G. Copeland, PhD., Cynthia Dunbar

Blood (2009) 114 (22): 3979.

https://doi.org/10.1182/blood.V114.22.3979.3979

Published: 2009

Journal Articles

A Phase II Trial of Pulse Dosing Lenalidomide: 3 Weeks On 3 Weeks off in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Georg Aue, MD, Susan Soto, RN, Janet Valdez, PA, Diane C. Arthur, MD, Mark Roschewski, MD, Adrian Wiestner, MD, PhD

Blood (2009) 114 (22): 3427.

https://doi.org/10.1182/blood.V114.22.3427.3427

Published: 2009

Journal Articles

Lenalidomide Induced Cytokine Release Syndrome in Chronic Lymphocytic Leukemia (CLL): Clinical and Laboratory Correlates of Immune Activation.

Georg Aue, MD, Ndegwa Njuguna, MD, Xin Tian, PhD, Janet Valdez, PA, Susan Soto, RN, J. Philip McCoy, Jr., PhD, Leigh Samsel, Berengere Vire, PhD, Keyvan Keyvanfar, Stefania Pittaluga, MD, Adrian Wiestner, MD, PhD

Blood (2008) 112 (11): 2099.

https://doi.org/10.1182/blood.V112.11.2099.2099

Published: 2008

Journal Articles

PU.1 Cooperates with SOX4 in Myeloid Cells.

Georg Aue, MD, Yang Du, PhD, Nancy A. Jenkins, PhD, Cynthia E. Dunbar, MD, Neal G. Copeland, PhD

Blood (2007) 110 (11): 2633.

https://doi.org/10.1182/blood.V110.11.2633.2633

Published: 2007

Journal Articles

PU.1 Is a Downstream Target of SOX4 in Myeloid Cells.

Georg Aue, MD, Yang Du, Ph.D., Cynthia E. Dunbar, M.D., Nancy A. Jenkins, Ph.D., Neal G. Copeland, Ph.D.

Blood (2006) 108 (11): 2217.

https://doi.org/10.1182/blood.V108.11.2217.2217

Published: 2006

Journal Articles

DIC with Ulcerative Colitis: The Combined Effects of Prothrombin G20210A, APC Resistance, and Endotoxemia⇒.

Georg Aue, MD, Nancy Carroll, MD, McDonald Horne, MD.

Blood (2004) 104 (11): 4034.

https://doi.org/10.1182/blood.V104.11.4034.4034

Published: 2004

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Rapid Engraftment, Immune Recovery, and Resolution of Transfusion Dependence in Treatment-Refractory Severe Aplastic Anemia Following Transplantation with Ex Vivo Expanded Umbilical Cord Blood (Omidubicel)

Single Agent Ibrutinib (PCI-32765) Achieves Equally Good and Durable Responses In Chronic Lymphocytic Leukemia (CLL) Patients With and Without Deletion 17p

In Patients With Chronic Lymphocytic Leukemia (CLL) Ibrutinib Effectively Reduces Clonal IgM Paraproteins and Serum Free Light Chains While Increasing Normal IgM, IgA Serum Levels, Suggesting a Nascent Recovery Of Humoral Immunity

Ibrutinib (PCI 32765) Rapidly Improves Platelet Counts in Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (CLL/SLL) Patients and Has Minimal Effects On Platelet Aggregation

Phase I Study of On 01910.Na (rigosertib), a Multikinase PI3K Inhibitor in Relapsed/Refractory B-Cell Malignancies

In Vivo Effects of Ibrutinib On BCR Signaling, Tumor Cell Activation and Proliferation in Blood and Tissue-Resident Cells of Chronic Lymphocytic Leukemia Patients

Rapid Decrease in Overall Tumor Burden On Ibrutinib (PCI-32765) in CLL Despite Transient Increase in ALC Indicates a Significant Degree of Treatment Induced Cell Death.

Increased Incidence of Thrombosis with Lenalidomide in Chronic Lymphocytic Leukemia: Effect of Lenalidomide On Inflammation, Endothelial Cell Damage and Coagulation.

Sox4 Downregulates Pu.1 Gene Expression by Binding to An Upper Regulatory Element of Pu.1, a Mechanism Contributing to Leukemogenesis.

A Phase II Trial of Pulse Dosing Lenalidomide: 3 Weeks On 3 Weeks off in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Lenalidomide Induced Cytokine Release Syndrome in Chronic Lymphocytic Leukemia (CLL): Clinical and Laboratory Correlates of Immune Activation.

PU.1 Cooperates with SOX4 in Myeloid Cells.

PU.1 Is a Downstream Target of SOX4 in Myeloid Cells.

DIC with Ulcerative Colitis: The Combined Effects of Prothrombin G20210A, APC Resistance, and Endotoxemia⇒.

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