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Journal Articles

Essential Role for Phospholipase C Gamma 1 (PLC-γ1) in the Survival of t(8;21) Acute Myeloid Leukemia

Hasan Mahmud, PhD, Frank JG Scherpen, Tiny Meeuwsen-de Boer, Harm-Jan Lourens, Eveline S. de Bont
Journal: Blood
Blood (2016) 128 (22): 1699.
https://doi.org/10.1182/blood.V128.22.1699.1699
Published: 2016
Journal Articles

Kinome Profiling Identifies Phospholipase C Gamma 1 (PLCγ1) As a Potential Target for t(8;21) AML

Hasan Mahmud, PhD, Frank JG Scherpen, Tiny Meeuwsen-de Boer, Harm Jan Lourens, Eveline S. de Bont
Journal: Blood
Blood (2015) 126 (23): 1384.
https://doi.org/10.1182/blood.V126.23.1384.1384
Published: 2015
Journal Articles

Effect of IKZF1 Deletions on Signal Transduction Pathways in Philadelphia Chromosome-Negative B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Naomi E van der Sligte, Frank JG Scherpen, Arja ter Elst, PhD, Victor Guryev, PhD, Frank N van Leeuwen, PhD, Evelina SJM de Bont, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3770.
https://doi.org/10.1182/blood.V124.21.3770.3770
Published: 2014
Journal Articles

EphB1 Downregulation In Acute Myeloid Leukemia: Suppressing p53-Dependent DNA Damage Control System

Kim R Kampen, Frank JG Scherpen, Guillermo Garcia-Manero, MD, Hui Yang, MD, PhD., Steven M. Kornblau, MD, Evelina S.J.M. de Bont, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2484.
https://doi.org/10.1182/blood.V122.21.2484.2484
Published: 2013
Journal Articles

Insights in Dynamic Kinome Reprogramming As a Consequence of MEK Inhibition in MLL-Rearranged AML.

Kim R Kampen, Arja ter Elst, PhD, Sander H Diks, PhD, Frank JG Scherpen, Valerie De Haas, Maikel P Peppelenbosch, Evelina S. De Bont, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2338.
https://doi.org/10.1182/blood.V120.21.2338.2338
Published: 2012
Journal Articles

Cyclic-AMP Responsive Element Binding Protein 1 (CREB) As a New Potential Druggable Target in Pediatric Acute Lymphoblastic Leukemia

Naomi E van der Sligte, Arja ter Elst, PhD, Kim R Kampen, Frank JG Scherpen, Hendrik Mulder, Sander H Diks, PhD, Frank N. van Leeuwen, PhD, Evelina S. De Bont, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1368.
https://doi.org/10.1182/blood.V118.21.1368.1368
Published: 2011
Journal Articles

Epidermal Growth Factor Receptor Expression and Activity In Acute Myeloid Leukemia

Arja ter Elst, Steven M. Kornblau, MD, Frank jg Scherpen, Yi Hua Qiu, MD, Nianxiang Zhang, Kevin R Coombes, Evelina S. De Bont, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3144.
https://doi.org/10.1182/blood.V116.21.3144.3144
Published: 2010
Journal Articles

Targeting Multiple Active Kinase Pathways In 11q23 Translocated Pediatric Acute Myeloid Leukemia Using a VEGFR2 Antibody Together with a MEK Inhibitor.

Arja ter Elst, Kim R Kampen, Sander H Diks, Frank JG Scherpen, Válerie de Haas, MD, PhD, Maikel P Peppelenbosch, Evelina S. De Bont, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3626.
https://doi.org/10.1182/blood.V116.21.3626.3626
Published: 2010