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Journal Articles

Favorable Outcomes in Pediatric Patients in the Phase 3 Hgb-207 (Northstar-2) and Hgb-212 (Northstar-3) Studies of Betibeglogene Autotemcel Gene Therapy for the Treatment of Transfusion-Dependent β-Thalassemia

Alexis A. Thompson, MD, Janet L. Kwiatkowski, MD MSCE, John B. Porter, MA, MD, FRCP, FRCPath, Suradej Hongeng, MD, Evangelia Yannaki, MD, Andreas E. Kulozik, MD PhD, Martin G. Sauer, MD, Adrian J. Thrasher, MBBS, PhD FMedSci, Isabelle Thuret, MD, Ashutosh Lal, MD, Ruiting Guo, MS, Weijian Liu, PhD, Richard A. Colvin, MD PhD, Mark C. Walters, MD, Franco Locatelli, MD PhD

Blood (2020) 136 (Supplement 1): 52–54.

https://doi.org/10.1182/blood-2020-135857

Published: 2020

Journal Articles

In Vivo HSC Gene Therapy for Hemoglobinopathies: A Proof of Concept Evaluation in Rhesus Macaques

Chang Li, Hongjie Wang, PhD, Sucheol Gil, Afrodite Georgakopoulou, PhDstudent, Stefan Radtke, PhD, Evangelia Yannaki, MD, Thalia Papayannopoulou, MD DrSci, Hans-Peter Kiem, MDPhD, Andre Lieber, MD PhD

Blood (2020) 136 (Supplement 1): 46–47.

https://doi.org/10.1182/blood-2020-141468

Published: 2020

Journal Articles

Response of Patients with Transfusion-Dependent β-Thalassemia (TDT) to Betibeglogene Autotemcel (beti-cel; LentiGlobin for β-Thalassemia) Gene Therapy Based on HBB Genotype and Disease Genetic Modifiers

Mark C. Walters, MD, David H.K. Chui, MD FRCPC, John J Farrell, PhD, Ashutosh Lal, MD, Franco Locatelli, MD PhD, Janet L. Kwiatkowski, MD MSCE, John B. Porter, MA, MD, FRCP, FRCPath, Martin G. Sauer, MD, Isabelle Thuret, MD, Suradej Hongeng, MD, Andreas E. Kulozik, MD PhD, Adrian J. Thrasher, MBBS, PhD FMedSci, Evangelia Yannaki, MD, Julia Yang, Dustin Whitney, PhD, Alexandria Petrusich, Richard A. Colvin, MD PhD, Alexis A. Thompson, MD

Blood (2020) 136 (Supplement 1): 1–3.

https://doi.org/10.1182/blood-2020-137642

Published: 2020

Journal Articles

Pre-Emptive Use of Rituximab in Epstein-Barr Virus Reactivation: Incidence, Predictive Factors, Monitoring, and Outcomes

Apostolia Papalexandri, MD, Eleni Gavriilaki, MD, Anna Vardi, MD PhD, Eirini Baldoumi, Christos Demosthenous, MD, Natasa Konstantinou, MD, Tasoula Touloumenidou, Panagiota Zerva, Fotini Kika, Angeliki Paleta, Michalis Iskas, Ioannis Batsis, Despina Mallouri, Evangelia Yannaki, MD, Ioanna Sakellari, MDPhD, Achilles Anagnostopoulos

Blood (2020) 136 (Supplement 1): 31.

https://doi.org/10.1182/blood-2020-141596

Published: 2020

Journal Articles

Easix Is Strongly Associated with Complement Activation and Overall Survival in Adult Allogeneic Hematopoietic Cell Transplantation Recipients

Eleni Gavriilaki, MD, Ioanna Sakellari, Thomas Chatziconstantinou, Despina Mallouri, Ioannis Batsis, Anna Vardi, MD PhD, Zoi Bousiou, MD MSc, Evdoxia Koravou, Marianna Masmanidou, Tasoula Touloumenidou, Lila Papalexandri, MD, Anastasia Athanasiadou, MD, Evangelia Yannaki, MD, Achilles Anagnostopoulos

Blood (2019) 134 (Supplement_1): 4520.

https://doi.org/10.1182/blood-2019-125332

Published: 2019

Journal Articles

Northstar-3: Interim Results from a Phase 3 Study Evaluating Lentiglobin Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia and Either a β0 or IVS-I-110 Mutation at Both Alleles of the HBB Gene

Ashutosh Lal, MD, Franco Locatelli, MD PhD, Janet L. Kwiatkowski, MD MSCE, Andreas E. Kulozik, MD PhD, Evangelia Yannaki, MD, John B. Porter, MA MDFRCP FRCPath, Isabelle Thuret, MD, Martin G. Sauer, MD, Heidi Elliot, Ying Chen, PhD, Richard A. Colvin, MD PhD, Alexis A. Thompson, MD MPH

Blood (2019) 134 (Supplement_1): 815.

https://doi.org/10.1182/blood-2019-128482

Published: 2019

Journal Articles

Pre-Transplant Genetic Susceptibility in Adult Allogeneic Hematopoietic Cell Transplant Recipients: Incidence and Clinical Relevance in Transplant-Associated Thrombotic Microangiopathy

Blood (2018) 132 (Supplement 1): 3401.

https://doi.org/10.1182/blood-2018-99-112041

Published: 2018

Journal Articles

Neurological Adverse Events Determine Morbidity and Mortality Post Allogeneic Hematopoietic Cell Transplantation

Ioanna Sakellari, Eleni Gavriilaki, MD, Sotirios Papagiannopoulos, Maria Gavriilaki, MD, Ioannis Batsis, Despina Mallouri, Anna Vardi, MD PhD, Varnavas Constantinou, Michalis Iskas, Marianna Masmanidou, Evangelia Yannaki, MD, Triantafyllos Geroukis, MD, Dimitrios Kazis, Vasilis Kimiskidis, Achilles Anagnostopoulos

Blood (2018) 132 (Supplement 1): 5732.

https://doi.org/10.1182/blood-2018-99-112032

Published: 2018

Journal Articles

Lentiglobin Gene Therapy for Patients with Transfusion-Dependent β-Thalassemia (TDT): Results from the Phase 3 Northstar-2 and Northstar-3 Studies

Franco Locatelli, Mark C. Walters, MD, Janet L. Kwiatkowski, MD, John Porter, MA MDFRCP FRCPath, Martin G. Sauer, MD, Isabelle Thuret, MD, Suradej Hongeng, MD, Andreas E. Kulozik, MD PhD, Ashutosh Lal, MD, Adrian J. Thrasher, MD PhD FMedSci, Evangelia Yannaki, MD, Heidi Elliot, Ge Tao, PhD, Mohammed Asmal, MD PhD, Alexis A. Thompson, MD MPH

Blood (2018) 132 (Supplement 1): 1025.

https://doi.org/10.1182/blood-2018-99-112667

Published: 2018

Journal Articles

High-Throughput T Cell Receptor (TR) Repertoire Analysis of Virus-Specific T Cells: Implications for T Cell Immunotherapy and Viral Infection Risk Stratification

Chrysi Galigalidou, Anastasia Papadopoulou, PhD, Evangelia Stalika, Andreas Agathangelidis, PhD, Elisavet Vlachonikola, Katerina Gemenetzi, Kiriakos Koukoulias, Kostas Pasentsis, Achilles Anagnostopoulos, Kostas Stamatopoulos, MD PhD, Evangelia Yannaki, MD, Anastasia Hadzidimitriou, PhD

Blood (2018) 132 (Supplement 1): 2057.

https://doi.org/10.1182/blood-2018-99-118851

Published: 2018

Journal Articles

Thalassemia Gene Therapy By In Vivo Transduction of Mobilized Hematopoietic Stem Cells (HSCs) with an Integrating Hybrid Adenovirus Vector System

Afrodite Georgakopoulou, PhDstudent, Hongjie Wang, PhD, Chrysi Kapsali, Undergraduate, Nikoleta Psatha, PhD, Angeliki Koufali, Graduate, Chang Li, PhD, Zsuzsanna Izsvak, PhD, Achilles Anagnostopoulos, Thalia Papayannopoulou, MD DrSci, Evangelia Yannaki, MD, Andre Lieber, MD PhD

Blood (2018) 132 (Supplement 1): 2193.

https://doi.org/10.1182/blood-2018-99-116787

Published: 2018

Journal Articles

Results from the Hgb-207 (Northstar-2) Trial: A Phase 3 Study to Evaluate Safety and Efficacy of Lentiglobin Gene Therapy for Transfusion-Dependent β-Thalassemia (TDT) in Patients with Non-β 0 /β 0 Genotypes

Mark C. Walters, MD, Suradej Hongeng, MD, Janet L. Kwiatkowski, MD, Franco Locatelli, MD PhD, John B. Porter, BA MB BChir MRCP(Path) FRCP(Path) MD, Martin G. Sauer, Adrian J Thrasher, MD PhD FMedSci, Isabelle Thuret, MD, Evangelia Yannaki, MD PhD, Heidi Elliot, Marisa Gayron, Mohammed Asmal, MD PhD, Alexis A Thompson, MD MPH

Blood (2017) 130 (Supplement 1): 526.

https://doi.org/10.1182/blood.V130.Suppl_1.526.526

Published: 2017

Journal Articles

Efficacy and Toxicity of Donor Lymphocyte Infusions in Relapsed Acute Myeloid Leukemia Post Allogeneic Hematopoietic Cell Transplantation: Single-Center Experience

Ioanna Sakellari, Varnavas Konstantinou, Eleni Gavriilaki, MD PhD, Despina Mallouri, Ioannis Batsis, MD, Vassiliki Kalaitzidou, Chrysa Apostolou, Maria Kaliou, Anastasia Bouinta, Christos Smias, MD, Panayotis Kaloyannidis, MD, Damianos Sotiropoulos, MD, Evangelia Yannaki, MD, Achilles Anagnostopoulos

Blood (2016) 128 (22): 5804.

https://doi.org/10.1182/blood.V128.22.5804.5804

Published: 2016

Journal Articles

Impact of Immune Reconstitution (IR) and Graft-Versus-Host Disease (GvHD) on Clinical Outcomes after Treatment with Donor T Cells Transduced to Express the Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK cells) in Acute Leukemia Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)

Blood (2016) 128 (22): 4599.

https://doi.org/10.1182/blood.V128.22.4599.4599

Published: 2016

Journal Articles

Transplant-Associated Thrombotic Microangiopathy: Prevalence, Prognostic Factors and Treatment Outcomes in Unrelated Allogeneic Transplant for Hematologic Diseases

Ioanna Sakellari, Ioannis Batsis, MD, Zoi Boussiouu, Despina Mallouri, Varnavas Konstantinou, Michail Iskas, MD, Anna Vardi, Stergios Papadimitriou, MDResident, Alkistis Panteliadou, Christos Smias, MD, Evangelia Yannaki, MD, Asimina Fylaktou, Aliki Tsompanakou, Chrysanthi Vadikoliou, Panayotis Kaloyannidis, MD, Taisir Natse, Gerasimos Bamichas, Eleni Gavriilaki, MD PhD, Achilles Anagnostopoulos

Blood (2016) 128 (22): 982.

https://doi.org/10.1182/blood.V128.22.982.982

Published: 2016

Journal Articles

An Optimized, Large Scale Generation and Validation of Aspergillus-Specific T Lymphocytes for the Management of Invasive Aspergillosis in Immunocompromised Patients

Anastasia Papadopoulou, PhD, Panayotis Kaloyannidis, MD, Maria Alvanou, Joanne Kalogeropoulou, Achilles Anagnostopoulos, Evangelia Yannaki, MD

Blood (2015) 126 (23): 4293.

https://doi.org/10.1182/blood.V126.23.4293.4293

Published: 2015

Journal Articles

Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies

Fyodor D Urnov, PhD, Andreas Reik, PhD, Jeff Vierstra, PhD, Kai-Hsin Chang, PhD, Yuanyue Zhou, Andrea Mich, Jennifer Adrian, Lisa Fox, Nikoletta Psatha, PhD, Siyuan Tan, PhD, Evangelia Yannaki, MD, Stewart Craig, PhD, Edward J. Rebar, PhD, John Stamatoyannopoulos, MD, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD DSci, Haiyan Jiang, PhD

Blood (2015) 126 (23): 204.

https://doi.org/10.1182/blood.V126.23.204.204

Published: 2015

Journal Articles

Survival Advantage with Comparable Complete Chimerism Patterns in Reduced Toxicity Treosulfan-Based Vs Reduced Intensity Busulfan-Based Conditinioning Regimen in AML/MDS Patients Undergoing Allogeneic Haematopoietic Cell Transplantation

Ioannis Batsis, MD, Ioanna Sakellari, MD PhD, Apostolia Papalexandri, Despina Mallouri, Sofia Charalampidou, Maria Kaliou, Achilleas Afisidis, Eleni Gavriilaki, MD, Varnavas C Constantinou, MD, Evangelia Yannaki, MD, Panayotis Kaloyannidis, MD, Chrysa Apostolou, Damianos Sotiropoulos, MD, Chrysanthi Vadikolia, MD, Christos Smias, MD, Achilles Anagnostopoulos

Blood (2015) 126 (23): 1914.

https://doi.org/10.1182/blood.V126.23.1914.1914

Published: 2015

Journal Articles

An Optimized, Ex Vivo Log-Scale Expansion of UCB-Derived Myeloid Dcs, Towards Efficient Cancer Immunotherapy

Eleni Gounari, Anastasia Papadopoulou, PhD, Minas Yiangou, Prof, Angeliki E Xagorari, PhD, Achilles Anagnostopoulos, MD, Evangelia Yannaki, MD, Panayotis Kaloyannidis, MD

Blood (2014) 124 (21): 2441.

https://doi.org/10.1182/blood.V124.21.2441.2441

Published: 2014

Journal Articles

Infusion of Donor Lymphocytes Genetically Engineered to Express the Herpes Simplex Virus Thymidine Kinase (HSV-TK) Suicide Gene after Haploidentical Hematopoietic Stem Cell Transplantation (HSCT): Preliminary Efficacy Data from the Randomized TK008 Study

Blood (2014) 124 (21): 2535.

https://doi.org/10.1182/blood.V124.21.2535.2535

Published: 2014

NARROW

Favorable Outcomes in Pediatric Patients in the Phase 3 Hgb-207 (Northstar-2) and Hgb-212 (Northstar-3) Studies of Betibeglogene Autotemcel Gene Therapy for the Treatment of Transfusion-Dependent β-Thalassemia

In Vivo HSC Gene Therapy for Hemoglobinopathies: A Proof of Concept Evaluation in Rhesus Macaques

Response of Patients with Transfusion-Dependent β-Thalassemia (TDT) to Betibeglogene Autotemcel (beti-cel; LentiGlobin for β-Thalassemia) Gene Therapy Based on HBB Genotype and Disease Genetic Modifiers

Pre-Emptive Use of Rituximab in Epstein-Barr Virus Reactivation: Incidence, Predictive Factors, Monitoring, and Outcomes

Easix Is Strongly Associated with Complement Activation and Overall Survival in Adult Allogeneic Hematopoietic Cell Transplantation Recipients

Northstar-3: Interim Results from a Phase 3 Study Evaluating Lentiglobin Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia and Either a β0 or IVS-I-110 Mutation at Both Alleles of the HBB Gene

Pre-Transplant Genetic Susceptibility in Adult Allogeneic Hematopoietic Cell Transplant Recipients: Incidence and Clinical Relevance in Transplant-Associated Thrombotic Microangiopathy

Neurological Adverse Events Determine Morbidity and Mortality Post Allogeneic Hematopoietic Cell Transplantation

Lentiglobin Gene Therapy for Patients with Transfusion-Dependent β-Thalassemia (TDT): Results from the Phase 3 Northstar-2 and Northstar-3 Studies

High-Throughput T Cell Receptor (TR) Repertoire Analysis of Virus-Specific T Cells: Implications for T Cell Immunotherapy and Viral Infection Risk Stratification

Thalassemia Gene Therapy By In Vivo Transduction of Mobilized Hematopoietic Stem Cells (HSCs) with an Integrating Hybrid Adenovirus Vector System

Results from the Hgb-207 (Northstar-2) Trial: A Phase 3 Study to Evaluate Safety and Efficacy of Lentiglobin Gene Therapy for Transfusion-Dependent β-Thalassemia (TDT) in Patients with Non-β 0 /β 0 Genotypes

Efficacy and Toxicity of Donor Lymphocyte Infusions in Relapsed Acute Myeloid Leukemia Post Allogeneic Hematopoietic Cell Transplantation: Single-Center Experience

Transplant-Associated Thrombotic Microangiopathy: Prevalence, Prognostic Factors and Treatment Outcomes in Unrelated Allogeneic Transplant for Hematologic Diseases

An Optimized, Large Scale Generation and Validation of Aspergillus-Specific T Lymphocytes for the Management of Invasive Aspergillosis in Immunocompromised Patients

Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies

Survival Advantage with Comparable Complete Chimerism Patterns in Reduced Toxicity Treosulfan-Based Vs Reduced Intensity Busulfan-Based Conditinioning Regimen in AML/MDS Patients Undergoing Allogeneic Haematopoietic Cell Transplantation

An Optimized, Ex Vivo Log-Scale Expansion of UCB-Derived Myeloid Dcs, Towards Efficient Cancer Immunotherapy

Infusion of Donor Lymphocytes Genetically Engineered to Express the Herpes Simplex Virus Thymidine Kinase (HSV-TK) Suicide Gene after Haploidentical Hematopoietic Stem Cell Transplantation (HSCT): Preliminary Efficacy Data from the Randomized TK008 Study

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American Society of Hematology

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American Society of Hematology

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