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Esteban Braggio, Ph.D.
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Journal Articles

Intracellular Accumulation Of Light Chains Caused By Lenalidomide, and Mediated Via CRBN, Causes Major ER Stress and Is Implicated In The Synergistic Combination Of Imids and Proteasome Inhibitors

Sinto Sebastian, Ph.D., Yuan Xiao Zhu, PhD, Esteban Braggio, Ph.D., Sonali Panchabhai, MBBS, Chang-Xin Shi, Ph.D., Gregory Ahmann, BS, Leif Bergsagel, M.D., Rafael Fonseca, M.D.
Journal: Blood
Blood (2013) 122 (21): 4434.
https://doi.org/10.1182/blood.V122.21.4434.4434
Published: 2013
Journal Articles

Development Of a 47 Gene Sequencing Panel For Common Mutations Present In Multiple Myeloma : Preliminary Results In 77 p53 Deleted Patients

K. Martin Kortuem, MD, Christian Langer, MD, Esteban Braggio, Ph.D., Scott Van Wier, Jan Egan, PhD, Laura Bruins, Jessica Schmidt, Lars Bullinger, MD, PhD, Miriam Kull, MD, Stefan Knop, MD, Hermann Einsele, MD, A. Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2013) 122 (21): 4449.
https://doi.org/10.1182/blood.V122.21.4449.4449
Published: 2013
Journal Articles

Genomic Landscape and Clonal Heterogeneity Underlying Progression and Relapse In Chronic Lymphocytic Leukemia (CLL)

Juhi Ojha, PhD, Jackline Ayres-Silva, Charla Secreto, Scott Van Wier, Susan L Slager, PhD, Rafael Fonseca, M.D., Tait D Shanafelt, MD, Neil E. Kay, MD, Esteban Braggio, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 2855.
https://doi.org/10.1182/blood.V122.21.2855.2855
Published: 2013
Journal Articles

A Synthetic Lethality Druggable Genome RNAi Screen Identifies Genes Mediating Sensitivity To Lenalidomide In Multiple Myeloma Including RSK2

Yuan Xiao Zhu, Ph.D., Laura Bruins, Chang-Xin Shi, Ph.D., Jessica Schmidt, Chris Sereduk, Mia Champion, Ph.D., Esteban Braggio, Ph.D., Holly Yin, Ph.D., A. Keith Stewart, MBChB
Journal: Blood
Blood (2013) 122 (21): 3084.
https://doi.org/10.1182/blood.V122.21.3084.3084
Published: 2013
Journal Articles

Activation Of TAK1 By MYD88 L265P Drives Malignant B Cell Growth In Non-Hodgkin Lymphomas

Stephen M Ansell, M.D., Ph.D., Lucy S. Hodge, PharmD, Ph.D., Frank Secreto, Michelle Manske, Esteban Braggio, Ph.D., TAmmy Price-Troska, Steven Ziesmer, Ying Li, Sarah Johnson, Steven Hart, Jean-Pierre Kocher, George Vasmatzis, PhD, Asher Chanan-Khan, MD, Morie Abraham Gertz, MD, Rafael Fonseca, MD, Ahmet Dogan, MD, PhD, James R Cerhan, MD, PhD, Anne J. Novak, PhD
Journal: Blood
Blood (2013) 122 (21): 245.
https://doi.org/10.1182/blood.V122.21.245.245
Published: 2013
Journal Articles

The Genomic Landscape Of Primary Central Nervous System Lymphomas

Esteban Braggio, Ph.D., Brian Patrick O'Neill, MD, Scott Van Wier, Juhi Ojha, PhD, Jackline ayres-Silva, Riccardo Valdez, MD, Jan Egan, PhD, Ellen McPhail, MD, Maria Beatriz Lopes, David Schiff, MD, Raoul Tibes, MD, Keith Stewart, MBA, MB, CHB, Rafael Fonseca, M.D.
Journal: Blood
Blood (2013) 122 (21): 504.
https://doi.org/10.1182/blood.V122.21.504.504
Published: 2013
Journal Articles

Cereblon Expression Predicts Response, Progression Free and Overall Survival After Pomalidomide and Dexamethasone Therapy in Multiple Myeloma

Steven R. Schuster, MD, Klaus Martin Kortuem, MD, Yuan Xiao Zhu, PhD, Esteban Braggio, Ph.D., Chang-Xin Shi, PhD, Laura Bruins, Jessica Schmidt, Gregory Ahmann, BS, Shaji K. Kumar, MD, S. Vincent Rajkumar, Joseph R. Mikhael, MD, Vivek Roy, M.D., Betsy R. LaPlant, Kristina Laumann, Bart Barlogie, MD, John D Shaughnessy, Jr., PhD, Rafael Fonseca, MD, Leif Bergsagel, MD, Martha Q Lacy, MD, Keith Stewart, MD
Journal: Blood
Blood (2012) 120 (21): 194.
https://doi.org/10.1182/blood.V120.21.194.194
Published: 2012
Journal Articles

Genome-Wide Analysis Uncovers Recurrent Alterations in Primary Central Nervous System Lymphomas

Esteban Braggio, Ph.D., Brian Patrick O'Neill, MD, Jan Egan, PhD, Riccardo Valdez, MD, Ellen McPhail, MD, Maria Lopes, MD, David Schiff, MD, Raoul Tibes, MD, PhD, Keith Stewart, MD, Rafael Fonseca, MD
Journal: Blood
Blood (2012) 120 (21): 420.
https://doi.org/10.1182/blood.V120.21.420.420
Published: 2012
Journal Articles

Genome Wide Studies in Multiple Myeloma Identify XPO1/CRM-1 As a Critical Target Validated Using the Selective Inhibitor of Nuclear Export (SINE) KPT-276

Jessica Schmidt, Esteban Braggio, Ph.D., Marta Chesi, PhD, Jan Egan, PhD, Yuan Xiao Zhu, PhD, Chang-Xin Shi, PhD, Stephen Palmer, Victoria Garbitt, Dilara McCauley, PhD, Sharon Shacham, PhD MBA, Michael Kauffman, MD, PhD, Leif Bergsagel, MD, Keith Stewart, MD
Journal: Blood
Blood (2012) 120 (21): 573.
https://doi.org/10.1182/blood.V120.21.573.573
Published: 2012
Journal Articles

PARP Inhibition (OLAPARIB) Enhance Melphalan and Nutlin-3a Sensitivity in TP53 Positive Multiple Myeloma

Sinto Sebastian, Ph.D., Marta Chesi, PhD, Esteban Braggio, Ph.D., Leif Bergsagel, MD, Keith Stewart, MBA, MB, CHB, Gregory Ahmann, BS, Rafael Fonseca, MD
Journal: Blood
Blood (2012) 120 (21): 1846.
https://doi.org/10.1182/blood.V120.21.1846.1846
Published: 2012
Journal Articles

Cereblon Binding IMiD Small Molecules Mediate Myeloma Cell Death Via IRF4

Yuan Xiao Zhu, Ph.D., Chang-Xin Shi, Ph.D., Laura Bruins, Klaus Martin Kortuem, MD, Jessica Schmidt, Xiu-Bao Chang, Ph.D., Esteban Braggio, Ph.D., Leif Bergsagel, M.D., Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 1807.
https://doi.org/10.1182/blood.V120.21.1807.1807
Published: 2012
Journal Articles

MYD88 Pathway Activation in Lymphoplasmacytic Lymphoma Drives Tumor Cell Growth and Cytokine Expression.

Stephen M Ansell, M.D., Ph.D., Frank J Secreto, Ph.D., Michelle Manske, Esteban Braggio, Ph.D., Lucy S. Hodge, PharmD, Ph.D., Tammy Price-Troska, Steven C. Ziesmer, Asher Alban Chanan-Khan, M.D., Morie A Gertz, M.D., Ahmet Dogan, MD, PhD, James R Cerhan, MD, PhD, Anne J Novak, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 2699.
https://doi.org/10.1182/blood.V120.21.2699.2699
Published: 2012