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Erwin M Lee, PhD
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Journal Articles

Inhibition of Telomerase with Imetelstat Is Detrimental to Leukemia Stem Cells in Acute Myeloid Leukemia (AML)

Claudia Bruedigam, Frederik Otzen Bagger, Florian H Heidel, MD, Catherine Kuhn, Solene Guignes, Axia Song, Rebecca Austin, Therese Vu, Erwin M Lee, PhD, Andrew S. Moore, MBBS, FRACP, PhD, Richard B. Lock, PhD, Lars Bullinger, MD PhD, Geoff R Hill, MD, Steven W Lane, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2322.
https://doi.org/10.1182/blood.V124.21.2322.2322
Published: 2014
Journal Articles

CSL362: A Monoclonal Antibody to Human Interleukin-3 Receptor (CD123), Optimized for NK Cell-Mediated Cytotoxicity of AML Stem Cells

Samantha J. Busfield, PhD, Mark Biondo, PhD, Mae Wong, PhD, Hayley S. Ramshaw, PhD, Erwin M Lee, PhD, Kirstee Martin, PhD, Souravi Ghosh, PhD, Hal Braley, Vesna Tomasetig, Con Panousis, PhD, Gino Vairo, PhD, Andrew W. Roberts, MBBS, PhD, Simon Z. He, MBBS, Naomi Sprigg, Daniel Thomas, MBBS, PhD, Mark DeWitte, VMD, Richard B. Lock, PhD, Angel F. Lopez, MBBS, PhD, Andrew Nash, PhD
Journal: Blood
Blood (2012) 120 (21): 3598.
https://doi.org/10.1182/blood.V120.21.3598.3598
Published: 2012
Journal Articles

A Neutralizing Antibody (CSL362) Against the Interleukin-3 Receptor α-Chain Augments the Efficacy of a Cytarabine/Daunorubicin Induction-Type Therapy in Preclinical Xenograft Models of Acute Myelogenous Leukemia

Erwin M Lee, PhD, Dean Yee, PhD, Samantha J Busfield, PhD, Gino Vairo, PhD, Richard B. Lock, PhD
Journal: Blood
Blood (2012) 120 (21): 3599.
https://doi.org/10.1182/blood.V120.21.3599.3599
Published: 2012
Journal Articles

CD123 (IL-3 Receptor α Chain) Neutralization by a Monoclonal Antibody Selectively Eliminates Human Acute Myeloid Leukemic Stem Cells.

Richard B. Lock, PhD, Liqing Jin, PhD, Erwin M. Lee, PhD, Hayley S. Ramshaw, PhD, Sam Busfield, PhD, Armando G. Peoppl, BSc, Lucy Wilkinson, BSc, Mark A. Guthridge, PhD, Andrew Boyd, PhD, David Gearing, PhD, Gino Vairo, PhD, Angel Lopez, MD, PhD, John E. Dick, PhD
Journal: Blood
Blood (2007) 110 (11): 161.
https://doi.org/10.1182/blood.V110.11.161.161
Published: 2007