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Enrico La Spina
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Journal Articles

Dexamethasone and Daratumumab Impair T-Cell Mediated Killing in Multiple Myeloma: Implications for Sequential Therapies

Ilaria Dulcamare, Sara Marino, Nunziatina Laura Parrinello, Grazia Scandura, Enrico La Spina, Daniela Cambria, Grazia Scuderi, Cesarina Giallongo, Daniele Tibullo, Alessandra Romano, Francesco Di Raimondo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6828.
https://doi.org/10.1182/blood-2024-206668
Published: 2024
Journal Articles

Arginine Deprivation Induces a Dormient Phenotype in Neoplastic Plasma Cells: The Seed and Soil in Multiple Myeloma

Grazia Scandura, Ilaria Dulcamare, Enrico La Spina, Caterina Dieni, Daniela Cambria, Cesarina Giallongo, Daniele Tibullo, Francesco Di Raimondo, Alessandra Romano
Journal: Blood
Blood (2024) 144 (Supplement 1): 5770.
https://doi.org/10.1182/blood-2024-206665
Published: 2024
Journal Articles

Lipid Handling Induces Ferroptosis and Conveys Sensitivity to Anti-BCMA Immunotherapy in Multiple Myeloma

Enrico La Spina, Salvatore Cortellino, Cesarina Giallongo, Marisabel Mecca, Simona Picerno, Angela Amoresano, Gabriella Pinto, Stefania Serpico, Alessandro Sgambato, Grazia Scandura, Daniela Cambria, Daniele Tibullo, Antonino Neri, Francesco Di Raimondo, Alessandra Romano
Journal: Blood
Blood (2023) 142 (Supplement 1): 4682.
https://doi.org/10.1182/blood-2023-186845
Published: 2023
Journal Articles

Lactate Transporters Modulate Stromal Cell Remodeling in Myeloproliferative Neoplasms (MPN)

Daniele Tibullo, Mariarita Spampinato, Andrea Duminuco, Enrico La Spina, Sebastiano Giallongo, Alessandra Romano, Grazia Scandura, Tatiana Zuppelli, Rosario Caltabiano, Lucia Salvatorelli, Giovanni Li Volti, Francesco Di Raimondo, Cesarina Giallongo, Giuseppe Alberto Palumbo
Journal: Blood
Blood (2023) 142 (Supplement 1): 1790.
https://doi.org/10.1182/blood-2023-187452
Published: 2023
Journal Articles

ROS-Driven Structural and Functional Fibrinogen Modifications Are Reverted By JAK Inhibition in Myeloproliferative Neoplasms

Daniele Tibullo, Giuseppe Alberto Palumbo, Cesarina Giallongo, Anna Longo, Andrea Duminuco, Francesco Di Raimondo, Enrico La Spina, Giovanni Li Volti, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Claudia Fiorillo, Niccolò Taddei, Matteo Becatti
Journal: Blood
Blood (2023) 142 (Supplement 1): 6334.
https://doi.org/10.1182/blood-2023-190029
Published: 2023
Journal Articles

Arginine Deprivation in Microenvironment Makes Multiple Myeloma Resistant to Proteasome Inhibitors Via Increased Lactate Release and Metabolic Rewiring

Cesarina Giallongo, Grazia Scandura, Alessandro Barbato, Enrico La Spina, Lucia Longhitano, Tatiana Zuppelli, Ilaria Dulcamare, Nunziatina Laura Parrinello, Sebastiano Giallongo, Francesca Polito, Rosaria Oteri, Mohammed Aguennouz, Giuseppe A. Palumbo, Marco Lolicato, Giovanni Li Volti, Francesco Di Raimondo, Daniele Tibullo, Alessandra Romano
Journal: Blood
Blood (2022) 140 (Supplement 1): 7102–7103.
https://doi.org/10.1182/blood-2022-170276
Published: 2022
Journal Articles

Dissecting the Adaptive Response to Arginine Deprivation in Hodgkin Lymphoma

Fabrizio Puglisi, Antonella Padella, Nunziatina Laura Parrinello, Grazia Scandura, Daniela Cambria, Enrico La Spina, Alessandro Barbato, Cesarina Giallongo, Daniele Tibullo, Giuseppe A. Palumbo, Claudio Cerchione, Giovanni Martinelli, Giorgia Simonetti, Francesco Di Raimondo, Alessandra Romano
Journal: Blood
Blood (2021) 138 (Supplement 1): 4497.
https://doi.org/10.1182/blood-2021-151006
Published: 2021
Journal Articles

CXCL12/CXCR4 Axis Drives Mitochondrial Trafficking in Tumor Myeloma Microenvironment

Cesarina Giallongo, Ilaria Dulcamare, Daniele Tibullo, Vittorio Del Fabro, Nunzio Vicario, Nunziatina Laura Parrinello, Alessandra Romano, Grazia Scandura, Alessandro Barbato, Enrico La Spina, Daniela Cambria, Giacomo Lazzarino, Concetta Conticello, Giovanni Li Volti, Giuseppe Musumeci, Giuseppe A. Palumbo, Francesco Di Raimondo
Journal: Blood
Blood (2021) 138 (Supplement 1): 2663.
https://doi.org/10.1182/blood-2021-152175
Published: 2021
Journal Articles

Lactate As Metabolic Link between Cancer Cells and Tumor Microenvironment in Myelofibrosis Patients

Cesarina Giallongo, PhD, Mariarita Spampinato, PhDstudent, Enrico La Spina, Nunziatina Laura Parrinello, PhD, Lucia Longhitano, PhDstudent, Rosario Caltabiano, MD, Lucia Salvatorelli, MD, Alessandra Romano, MDPhD, Alessandro Barbato, Michelino Di Rosa, PhD, Giacomo Lazzarino, PhD, Giovanni Li Volti, MD PhD, Francesco Di Raimondo, MD, Daniele Tibullo, PhD, Giuseppe A. Palumbo, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26.
https://doi.org/10.1182/blood-2020-142007
Published: 2020
Journal Articles

An Integrative Unbiased Global Analysis of the Metabolic Adaptive Response to Tryptophan Deprivation in Classical Hodgkin Lymphoma

Fabrizio Puglisi, Enrico La Spina, Alessandro Barbato, Grazia Scandura, Cesarina Giallongo, PhD, Daniele Tibullo, PhD, Francesco Di Raimondo, MD, Alessandra Romano, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-139748
Published: 2020
Journal Articles

The Heme Oxygenase-1/Carbon Monoxide Pathway Activates TLR4 Signaling Promoting Bortezomib Resistance in Multiple Myeloma Cells

Cesarina Giallongo, PhD, Grazia Scandura, Alessandro Barbato, Alessandra Romano, MDPhD, Fabrizio Puglisi, Daniela Cambria, Enrico La Spina, Giuseppe Musumeci, PhD, Michelino Di Rosa, PhD, Concetta Conticello, Giovanni Li Volti, MD PhD, Giuseppe A. Palumbo, MD PhD, Francesco Di Raimondo, MD, Daniele Tibullo, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-141838
Published: 2020