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Journal Articles

Combination of Interferon α, Delivered By Engineered Mesenchymal Stromal Cells, and Cytarabine Limits the Development of Acute Myeloid Leukemia, Potentially Targeting Leukemic Stem Cells

Desbourdes M. Laura, PhD, Suheyla Hasgur, DVM, PhD, Adam J Guess, Minjun Yu, PhD, Satoru Otsuru, MD PhD, Edwin M. Horwitz, MD PhD

Blood (2019) 134 (Supplement_1): 5143.

https://doi.org/10.1182/blood-2019-127456

Published: 2019

Journal Articles

Reduction in Bone Marrow Insulin-like Growth Factor-1 Levels Enhances Long-Term Hematopoietic Stem Cell Engraftment Following Bone Marrow Transplantation

Timothy S. Olson, MD PhD, Ji Zha, PhD BS, Lori Kunselman, Jian-Meng Fan, Edwin M. Horwitz, MD PhD

Blood (2017) 130 (Supplement 1): 68.

https://doi.org/10.1182/blood.V130.Suppl_1.68.68

Published: 2017

Journal Articles

Mesenchymal Stromal Cells Expressing Interferon α Limit the Development of Acute Myeloid Leukemia, Inducing Apoptosis In Vitro and In Vivo

Laura M Desbourdes, PhD, Adam J Guess, Suheyla Hasgur, DVM, PhD, Kathleen M Overholt, MD, Minjun Yu, PhD, Satoru Otsuru, MD PhD, Edwin M Horwitz, MD PhD

Blood (2016) 128 (22): 5216.

https://doi.org/10.1182/blood.V128.22.5216.5216

Published: 2016

Journal Articles

Cytomegalovirus Reactivation Does Not Increase Subsequent Risk for Acute Graft-Versus-Host Disease, Malignant Disease Relapse, or Infection Following Allogeneic Hematopoietic Cell Transplantation

Blood (2016) 128 (22): 3409.

https://doi.org/10.1182/blood.V128.22.3409.3409

Published: 2016

Journal Articles

Early Infection Attenuates Hematologic Malignant Disease Relapse Following Initial Allogeneic Hematopoietic Cell Transplantation

Blood (2016) 128 (22): 3410.

https://doi.org/10.1182/blood.V128.22.3410.3410

Published: 2016

Journal Articles

Adaptation of Marrow Osteoblast Morphology Mediated By a Hematopoietic-Derived Endosteal Cell Is Critical for Donor HSC Engraftment after BMT

Kathleen Overholt, MD, Satoru Otsuru, Victoria Best, Adam Guess, Timothy S. Olson, MD PhD, Massimo Dominici, MD, Edwin M. Horwitz, MD PhD

Blood (2015) 126 (23): 3603.

https://doi.org/10.1182/blood.V126.23.3603.3603

Published: 2015

Journal Articles

Enhancement of Megakaryocyte Interactions with the Osteoblastic Hematopoietic Stem Cell Niche Improves Engraftment Efficiency Following Hematopoietic Stem Cell Transplantation

Timothy S. Olson, MD, PhD, Satoru Otsuru, MD, PhD, Ted Hofmann, PhD, Edwin M. Horwitz, MD, PhD

Blood (2012) 120 (21): 211.

https://doi.org/10.1182/blood.V120.21.211.211

Published: 2012

Journal Articles

IGF1-Mediated Osteoblastic Niche Expansion After Marrow Ablation Enhances Long-Term Hematopoietic Stem Cell Engraftment and Hematopoietic Reconstitution After Bone Marrow Transplantation

Anna Caselli, Timothy S. Olson, MD, PhD, Satoru Otsuru, MD, Ph.D, Ted Hofmann, Paolo Paolucci, Massimo Dominici, MD, Edwin M. Horwitz, MD, PhD

Blood (2010) 116 (21): 557.

https://doi.org/10.1182/blood.V116.21.557.557

Published: 2010

Journal Articles

Novel Role for Host-Derived Megakaryocytes In Facilitating Stem Cell Engraftment through Enhancement of Osteoblastic Niche Restoration Following Radioablation

Timothy S. Olson, MD, PhD, Anna Caselli, Satoru Otsuru, MD, PhD, Ted Hofmann, PhD, Edwin M. Horwitz, MD, PhD

Blood (2010) 116 (21): 558.

https://doi.org/10.1182/blood.V116.21.558.558

Published: 2010

Journal Articles

Long-Term Survival and Late Deaths After Hematopoietic Stem Cell Transplantation for Primary Immunodeficiency Diseases and Inborn Errors of Metabolism.

Blood (2009) 114 (22): 3320.

https://doi.org/10.1182/blood.V114.22.3320.3320

Published: 2009

Journal Articles

0.1 Grams of Sub-Cutaneous Adipose Tissue (SCAT) as Source of Adult Multipotent Mesenchymal Stromal Cells (MSC) for Cell-Based Therapies.

Massimo Dominici, MD, Rita Sternieri, MD, Domenico De Fazio, MD, Luigi Cafarelli, MS, Giovanni Guaraldi, MD, Carlotta Spano, MS, Valeria Rasini, PhD, Paolo Paolucci, MD, PhD, Michele Cilli, VMD, Federica Piccardi, MS, Giuseppe Astori, PhD, Ted J. Hofmann, PhD, Edwin M. Horwitz, MD, PhD, Pierfranco Conte, MD, PhD

Blood (2007) 110 (11): 4915.

https://doi.org/10.1182/blood.V110.11.4915.4915

Published: 2007

Journal Articles

GD2+ Selected Mesenchymal Stromal Cells (MSCs) Demonstrate a More Robust Proliferation and Differentiation Potential Compared to Unselected Cells.

Caridad Martinez, MD, Ted J. Hofmann, PhD, Roberta Marino, MS, Massimo Dominici, MD, Edwin M. Horwitz, MD, PhD

Blood (2007) 110 (11): 1919.

https://doi.org/10.1182/blood.V110.11.1919.1919

Published: 2007

Journal Articles

Rapid Immune Reconstitution after a Reduced-Intensity Conditioning Regimen and a CD3-Depleted Haploidentical Stem Cell Graft for Pediatric Refractory Hematologic Malignancies.

Xiaohua Chen, MD, PhD, Gregory A. Hale, MD, Raymond C. Barfield, MD PhD, Ely Benaim, MD, Wing H. Leung, MD PhD, James Knowles, MS, Edwin M. Horwitz, MD PhD, Paul Woodard, MD, Kimberly A. Kasow, MD, Usman Yusuf, MD, Fred G. Behm, MD, Randall T. Hayden, MD, Sheila A. Shurtleff, PhD, Victoria Turner, PhD, Deo Kumar Srivastava, PhD, Rupert Handgretinger, MD PhD

Blood (2006) 108 (11): 5311.

https://doi.org/10.1182/blood.V108.11.5311.5311

Published: 2006

Journal Articles

High Dose Defibrotide as Therapy for Pediatric Patients with Veno-Occlusive Disease of the Liver.

Gregory A. Hale, MD, Renee M. Madden, MD, Kimberly A. Kasow, DO, Joseph Woodard, MD, Wing H. Leung, MD PhD, Raymond C. Barfield, MD PhD, Usman Yusuf, MD, Edwin M. Horwitz, MD PhD, Rupert Handgretinger, MD

Blood (2006) 108 (11): 2963.

https://doi.org/10.1182/blood.V108.11.2963.2963

Published: 2006

Journal Articles

CD3 Depleted Hematopoietic Peripheral Blood Stem Cell Grafts in Children with Refractory Hematologic Malignancies Undergoing Transplantation from Mismatched Related Donors.

Gregory A. Hale, MD, Kimberly A. Kasow, DO, Richard Lovins, RN, BSN, Joseph P. Woodard, MD, Wing H. Leung, MD, PhD, Usman Yusuf, MD, Edwin M. Horwitz, MD, PhD, Deo K. Srivastava, PhD, Xin Tong, MS, Ely Benaim, MD, Rupert Handgretinger, MD, PhD

Blood (2005) 106 (11): 5458.

https://doi.org/10.1182/blood.V106.11.5458.5458

Published: 2005

Journal Articles

Early Kinetics of Bone Marrow Cell Engraftment in Bone after Transplantation: Insights into the Mechanism of Engraftment.

John E. Garlits, MS, Massimo Dominici, MD, Ted J. Hofmann, PhD, Edwin M. Horwitz, MD, PhD

Blood (2004) 104 (11): 1294.

https://doi.org/10.1182/blood.V104.11.1294.1294

Published: 2004

NARROW

Combination of Interferon α, Delivered By Engineered Mesenchymal Stromal Cells, and Cytarabine Limits the Development of Acute Myeloid Leukemia, Potentially Targeting Leukemic Stem Cells

Reduction in Bone Marrow Insulin-like Growth Factor-1 Levels Enhances Long-Term Hematopoietic Stem Cell Engraftment Following Bone Marrow Transplantation

Mesenchymal Stromal Cells Expressing Interferon α Limit the Development of Acute Myeloid Leukemia, Inducing Apoptosis In Vitro and In Vivo

Cytomegalovirus Reactivation Does Not Increase Subsequent Risk for Acute Graft-Versus-Host Disease, Malignant Disease Relapse, or Infection Following Allogeneic Hematopoietic Cell Transplantation

Early Infection Attenuates Hematologic Malignant Disease Relapse Following Initial Allogeneic Hematopoietic Cell Transplantation

Adaptation of Marrow Osteoblast Morphology Mediated By a Hematopoietic-Derived Endosteal Cell Is Critical for Donor HSC Engraftment after BMT

Enhancement of Megakaryocyte Interactions with the Osteoblastic Hematopoietic Stem Cell Niche Improves Engraftment Efficiency Following Hematopoietic Stem Cell Transplantation

IGF1-Mediated Osteoblastic Niche Expansion After Marrow Ablation Enhances Long-Term Hematopoietic Stem Cell Engraftment and Hematopoietic Reconstitution After Bone Marrow Transplantation

Novel Role for Host-Derived Megakaryocytes In Facilitating Stem Cell Engraftment through Enhancement of Osteoblastic Niche Restoration Following Radioablation

Long-Term Survival and Late Deaths After Hematopoietic Stem Cell Transplantation for Primary Immunodeficiency Diseases and Inborn Errors of Metabolism.

0.1 Grams of Sub-Cutaneous Adipose Tissue (SCAT) as Source of Adult Multipotent Mesenchymal Stromal Cells (MSC) for Cell-Based Therapies.

GD2+ Selected Mesenchymal Stromal Cells (MSCs) Demonstrate a More Robust Proliferation and Differentiation Potential Compared to Unselected Cells.

Rapid Immune Reconstitution after a Reduced-Intensity Conditioning Regimen and a CD3-Depleted Haploidentical Stem Cell Graft for Pediatric Refractory Hematologic Malignancies.

High Dose Defibrotide as Therapy for Pediatric Patients with Veno-Occlusive Disease of the Liver.

CD3 Depleted Hematopoietic Peripheral Blood Stem Cell Grafts in Children with Refractory Hematologic Malignancies Undergoing Transplantation from Mismatched Related Donors.

Early Kinetics of Bone Marrow Cell Engraftment in Bone after Transplantation: Insights into the Mechanism of Engraftment.

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American Society of Hematology

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American Society of Hematology

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