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Journal Articles

Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models

Maurizio Zangari, MD, Ikjae Shin, PhD, Antonio Branca, MD, Hanna Yoo, MS, Sophia Fallo, Faith E Davies, MD, Benjamin Hoffman, PhD, Steven M. Fruchtman, MD, Donghoon Yoon, PhD

Blood (2016) 128 (22): 5664.

https://doi.org/10.1182/blood.V128.22.5664.5664

Published: 2016

Journal Articles

Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation

Antonio Branca, MD, Amy Buros, PhD, Donghoon Yoon, PhD, Larry J Suva, PhD, Niels Weinhold, PhD, Leo Rasche, MD, Carolina Schinke, MD, Sharmilan Thanendrarajan, MD, Meera Mohan, MD, Cerisse Harcourt, APRN, OCN, Faith E Davies, MD, Frits van Rhee, MD PhD, Gareth J Morgan, MD PhD, Maurizio Zangari, MD

Blood (2016) 128 (22): 4516.

https://doi.org/10.1182/blood.V128.22.4516.4516

Published: 2016

Journal Articles

Polycythemia of Mice with Human Gain-of-Function EPOR (mtH EPOR ) Is Transiently Corrected in Perinatal Life in Association with Low Epo and Increased Erythrocyte Phosphatidylserine Exposure

Jihyun Song, MS, Barbora Kralova, Monika Horvathova, PhD, Donghoon Yoon, PhD, Josef T. Prchal, MD, Vladimir Divoky, PhD

Blood (2015) 126 (23): 3335.

https://doi.org/10.1182/blood.V126.23.3335.3335

Published: 2015

Journal Articles

Thymus-Derived PTH (TPTH) Is Increased after Thyroparathyroidectomy in C57BL6/Kalwrij Mice and Modulates Mouse Sensitivity to 5TGM1 Myeloma Cell Line

Maurizio Zangari, MD, Hanna Yoo, Larry Suva, Donghoon Yoon, PhD

Blood (2015) 126 (23): 5335.

https://doi.org/10.1182/blood.V126.23.5335.5335

Published: 2015

Journal Articles

Higher Expressions of PTH Receptor Type 1 and/or 2 in Bone Marrow Is Associated to Longer Survival in Newly Diagnosed Myeloma Patients Enrolled in Total Therapy 3

Maurizio Zangari, MD, Caleb K Stein, MS, Shmuel Yaccoby, PhD, Donghoon Yoon, PhD, Christoph Heuck, MD, Yogesh Jethava, MB, MRCP, MD FRCPath, Donald Johann, MD MS, Rashid Z Khan, MD, Xenofon Papanikolaou, MD, Frits van Rhee, MD PhD, Faith E Davies, MD, Gareth J Morgan, MD PhD, Bart Barlogie, MD PhD

Blood (2014) 124 (21): 3409.

https://doi.org/10.1182/blood.V124.21.3409.3409

Published: 2014

Journal Articles

Waldenstrom's Macroglobulinemia Associated Bone Disease the UAMS Experience

Xenofon Papanikolaou, MD, Sarah Waheed, MD, Bart Barlogie, MD PhD, Daisy V. Alapat, MD, Donghoon Yoon, PhD, Manoj Kumar, MD, Aasiya Matin, MD, Hongyun Zhu, MD, Cerisse Harcourt, APN, Maurizio Zangari, MD

Blood (2014) 124 (21): 2999.

https://doi.org/10.1182/blood.V124.21.2999.2999

Published: 2014

Journal Articles

Surgical Control/Cure of 5TGM1 Murine Multiple Myeloma Model By Thyroparathyroidectomy

Maurizio Zangari, MD, Donghoon Yoon, PhD, Hanna Yoo, MS, Young Sik Kim, PhD

Blood (2014) 124 (21): 3387.

https://doi.org/10.1182/blood.V124.21.3387.3387

Published: 2014

Journal Articles

Molecular Basis of Neocytolysis.

Jihyun Song, M.S., Donghoon Yoon, PhD, Perumal Thiagarajan, MD, Josef T. Prchal, MD

Blood (2012) 120 (21): 2093.

https://doi.org/10.1182/blood.V120.21.2093.2093

Published: 2012

Journal Articles

Neocytolysis Is Associated with Changes in Increase of Mitochondrial Content and Impaired Protection From Reactive Oxygen Species

Jihyun Song, M.S., Donghoon Yoon, PhD, Perumal Thiagarajan, MD, Josef T. Prchal, MD

Blood (2011) 118 (21): 1029.

https://doi.org/10.1182/blood.V118.21.1029.1029

Published: 2011

Journal Articles

Tissue-Specific HIF-1 and HIF-2 Regulatory Elements and Their Roles in Erythropoietin Gene Expression

Donghoon Yoon, PhD, Jihyun Song, MS, Hyojin Kim, Bumjun Kim, PhD, Hyejin Shin, MS, Gregory Arnold, PhD, Steven Elliott, PhD, Josef T. Prchal, MD

Blood (2011) 118 (21): 1303.

https://doi.org/10.1182/blood.V118.21.1303.1303

Published: 2011

Journal Articles

MicroRNA-101 Is Down-Regulated In PV and ET Granulocytes and Its Decrease Is Associated with Over-Expression of Histone Methyltransferase In EZH2 In MPN Patients

Sabina Swierczek, PhD, Donghoon Yoon, PhD, Kimberly Hickman, BS, Josef T. Prchal, MD

Blood (2010) 116 (21): 1989.

https://doi.org/10.1182/blood.V116.21.1989.1989

Published: 2010

Journal Articles

Study of Two Subjects with Absence of Severe Anemia with Homozygous β 0 Thalassemia Due to Disrupted γ-to-β Switch

Donghoon Yoon, PhD, Soo Jin Kim, Kimberly Hickman, Dottie Hussey, Josef T. Prchal, MD

Blood (2010) 116 (21): 5172.

https://doi.org/10.1182/blood.V116.21.5172.5172

Published: 2010

Journal Articles

Methyl Dehydro-Jasmonate Has Anti-Inflammatory Effect Cells and Its Molecular Targets Mir-155 and NF-Kb Pathway against LPS Stimulation On RAW264.7.

Hye-Ja Lee, Hung-The Dang, Gyeoung-Jin Kang, Jee H Jung, PhD, Hee-Kyoung Kang, Hyejin Shin, MS, Josef T. Prchal, MD, Eun-Sook Yoo, PhD, Donghoon Yoon, PhD

Blood (2009) 114 (22): 1357.

https://doi.org/10.1182/blood.V114.22.1357.1357

Published: 2009

Journal Articles

TET2 Mutations in Polycythemia Vera (PV) in Some Cases Follow Rather Than Precede JAK2 V617F Mutation, Are Not a Disease-Initiating Event, Affect Mainly Erythropoiesis, and Contribute to Increased Aggressivity of PV Clone.

Sabina Swierczek, PhD, Christine Bellanne-Chantelot, Donghoon Yoon, PhD, Cecile Saint-Martin, Soo Jin Kim, Albert Najman, MD, Josef T. Prchal, MD

Blood (2009) 114 (22): 3913.

https://doi.org/10.1182/blood.V114.22.3913.3913

Published: 2009

Journal Articles

Increased Ratios of Internal Organ Volume to Body Mass in Chuvash Polycythemia and HIF-2α Repression of p21 Cip Expression through C-MYC.

Donghoon Yoon, PhD, David Okhotin, MD, Bumjun Kim, PhD, Yulia Okhotina, MD, Daniel J Okhotin, BS, Galina Y Miasnikova, MD, Adelina I Sergueeva, MD, Lydia A Polyakova, MD, Alexei Maslow, MD, Yonggu Lee, Gregg L Semenza, MD, PhD, Josef T. Prchal, MD, Victor R. Gordeuk, MD

Blood (2009) 114 (22): 5039.

https://doi.org/10.1182/blood.V114.22.5039.5039

Published: 2009

Journal Articles

HIF1 Induced Glutathione Dysregulation in Platelets Associated with Increased Risk of Vascular Disease in Chuvash Polycythemia.

Heather Gilbert, MD, Donghoon Yoon, PhD, Adelina I Sergueeva, Victor R. Gordeuk, MD, Josef T. Prchal, MD

Blood (2008) 112 (11): 1906.

https://doi.org/10.1182/blood.V112.11.1906.1906

Published: 2008

Journal Articles

Characterization of Tissue-Specific HIF-1 and HIF-2 Regulatory Elements of the Erythropoietin Gene

Donghoon Yoon, PhD, Hyojin Kim, Minyoung Jang, Jihyun Song, MS, Gregory E Arnold, PhD, Steve Elliott, PhD, Josef T. Prchal, MD

Blood (2008) 112 (11): 4763.

https://doi.org/10.1182/blood.V112.11.4763.4763

Published: 2008

Journal Articles

Truncated Human Erythropoietin Receptor Causes Fetal Polycythemia and Is Associated with a Prolonged Primitive Erythropoiesis and Hyperactive Definitive Erythropoiesis.

Donghoon Yoon, PhD, Josef Prchal, MD

Blood (2007) 110 (11): 3664.

https://doi.org/10.1182/blood.V110.11.3664.3664

Published: 2007

Journal Articles

Erythropoiesis in Polycythemia Vera Is Hyper-Proliferative and Has Accelerated Differentiation during In Vitro Erythroid Expansion and Is Associated with Higher Expressions of cMYB and EPOR at Early Erythroid Progenitors

Hana Bruchova, PhD, Donghoon Yoon, PhD, Archana Agarwal, MD, Eva Otahalova, Hyojin Kim, Josef T. Prchal, MD

Blood (2007) 110 (11): 1549.

https://doi.org/10.1182/blood.V110.11.1549.1549

Published: 2007

Journal Articles

Blast Transformation in a Patient with Primary Myelofibrosis Initiated from JAK2 V617F Progenitor.

Sabina I. Swierczek, PhD, Donghoon Yoon, PhD, Josef T. Prchal, MD

Blood (2007) 110 (11): 4665.

https://doi.org/10.1182/blood.V110.11.4665.4665

Published: 2007

NARROW

Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models

Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation

Polycythemia of Mice with Human Gain-of-Function EPOR (mtH EPOR ) Is Transiently Corrected in Perinatal Life in Association with Low Epo and Increased Erythrocyte Phosphatidylserine Exposure

Thymus-Derived PTH (TPTH) Is Increased after Thyroparathyroidectomy in C57BL6/Kalwrij Mice and Modulates Mouse Sensitivity to 5TGM1 Myeloma Cell Line

Higher Expressions of PTH Receptor Type 1 and/or 2 in Bone Marrow Is Associated to Longer Survival in Newly Diagnosed Myeloma Patients Enrolled in Total Therapy 3

Waldenstrom's Macroglobulinemia Associated Bone Disease the UAMS Experience

Surgical Control/Cure of 5TGM1 Murine Multiple Myeloma Model By Thyroparathyroidectomy

Molecular Basis of Neocytolysis.

Neocytolysis Is Associated with Changes in Increase of Mitochondrial Content and Impaired Protection From Reactive Oxygen Species

Tissue-Specific HIF-1 and HIF-2 Regulatory Elements and Their Roles in Erythropoietin Gene Expression

MicroRNA-101 Is Down-Regulated In PV and ET Granulocytes and Its Decrease Is Associated with Over-Expression of Histone Methyltransferase In EZH2 In MPN Patients

Study of Two Subjects with Absence of Severe Anemia with Homozygous β 0 Thalassemia Due to Disrupted γ-to-β Switch

Methyl Dehydro-Jasmonate Has Anti-Inflammatory Effect Cells and Its Molecular Targets Mir-155 and NF-Kb Pathway against LPS Stimulation On RAW264.7.

TET2 Mutations in Polycythemia Vera (PV) in Some Cases Follow Rather Than Precede JAK2 V617F Mutation, Are Not a Disease-Initiating Event, Affect Mainly Erythropoiesis, and Contribute to Increased Aggressivity of PV Clone.

Increased Ratios of Internal Organ Volume to Body Mass in Chuvash Polycythemia and HIF-2α Repression of p21 Cip Expression through C-MYC.

HIF1 Induced Glutathione Dysregulation in Platelets Associated with Increased Risk of Vascular Disease in Chuvash Polycythemia.

Characterization of Tissue-Specific HIF-1 and HIF-2 Regulatory Elements of the Erythropoietin Gene

Truncated Human Erythropoietin Receptor Causes Fetal Polycythemia and Is Associated with a Prolonged Primitive Erythropoiesis and Hyperactive Definitive Erythropoiesis.

Erythropoiesis in Polycythemia Vera Is Hyper-Proliferative and Has Accelerated Differentiation during In Vitro Erythroid Expansion and Is Associated with Higher Expressions of cMYB and EPOR at Early Erythroid Progenitors

Blast Transformation in a Patient with Primary Myelofibrosis Initiated from JAK2 V617F Progenitor.

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American Society of Hematology

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American Society of Hematology

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