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Donald J. Pinto
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Journal Articles

Dose-Dependent Antithrombotic Effects of Apixaban, an Oral Direct Factor Xa Inhibitor, in Prevention and Treatment of Thrombosis in Rabbit Models of Arteriovenous-Shunt and Venous Thrombosis at Doses That Preserve Hemostasis.

Pancras C. Wong, Earl J. Crain, Donald J. Pinto, Carol A. Watson
Journal: Blood
Blood (2007) 110 (11): 933.
https://doi.org/10.1182/blood.V110.11.933.933
Published: 2007
Journal Articles

The Direct Factor Xa Inhibitor Apixaban Produces Broad Antithrombotic Activity with Limited Effects on Bleeding Time in Rats.

William A. Schumacher, PhD, Jeffrey S. Bostwick, MS, Anne B. Stewart, BS, Thomas E. Steinbacher, BS, Donald J. Pinto, PhD, Pancras C. Wong, PhD
Journal: Blood
Blood (2007) 110 (11): 4005.
https://doi.org/10.1182/blood.V110.11.4005.4005
Published: 2007
Journal Articles

In Vitro Evaluation of Apixaban, a Novel, Potent, Selective and Orally Bioavailable Factor Xa Inhibitor.

Joseph M. Luettgen, BS, Tracy A. Bozarth, MS, Jeffrey M. Bozarth, BS, Frank A. Barbera, BS, Patrick Y. Lam, PhD, Mimi L. Quan, PhD, Donald J. Pinto, PhD, Ruth R. Wexler, PhD, Alan R. Rendina, PhD, Robert M. Knabb, PhD
Journal: Blood
Blood (2006) 108 (11): 4130.
https://doi.org/10.1182/blood.V108.11.4130.4130
Published: 2006
Journal Articles

Preclinical Pharmacokinetic and Metabolism of Apixaban, a Potent and Selective Factor Xa Inhibitor.

Kan He, PhD, Bing He, M.S., James E. Grace, M.S., Baomin Xin, Ph.D., Donglu Zhang, Ph.D., Donald J. Pinto, Ph.D., Joseph M. Luettgen, M.S., Robert M. Knabb, Ph.D., Patrick Y.S. Lam, Ph.D., Ruth R. Wexler, Ph.D., William G. Humphreys, Ph.D., Wen-Chyi Shyu, Ph.D., Scott J. Grossman, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 910.
https://doi.org/10.1182/blood.V108.11.910.910
Published: 2006
Journal Articles

Effects of the Factor Xa Inhibitor Apixaban on Venous Thrombosis and Hemostasis in Rabbits.

Pancras C. Wong, PhD, Carol A. Watson, BS, Earl J. Crain, BS, Joseph M. Luettgen, BS, Martin L. Ogletree, PhD, Ruth R. Wexler, PhD, Patrick Y.S. Lam, PhD, Donald J. Pinto, PhD, Robert M. Knabb, PhD
Journal: Blood
Blood (2006) 108 (11): 917.
https://doi.org/10.1182/blood.V108.11.917.917
Published: 2006