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Journal Articles

Targeted Non-Viral Gene Delivery through Transcutaneous Ultrasound Enables Robust, Redosable, Titratable, and Durable FVIII and FIX Gene Expression in the Liver in Murine Models

Blood (2024) 144 (Supplement 1): 2232.

https://doi.org/10.1182/blood-2024-208969

Published: 2024

Journal Articles

Engineering Non-Viral Gene Therapy Vector for Simultaneous Transgenic FVIII Protein Expression from Liver Sinusoidal Endothelial Cells (LSECs) and Hepatocytes upon Non-Invasive Transcutaneous Ultrasound-Mediated Gene Delivery

Ivan Krivega, Margarita Krivega, Julia Poniatowski, David Kim, Elizabeth Del Greco, Surabhi Rao, Victor Foster, Bert Frederich, Glenda Arauz, Celia Ortiz, Tanaya Ghosh, Oliver Chen, Dhruv Bole, Katelyn N Benthall, David Satyadi, Steve Feinstein, Kenneth Greenberg

Blood (2024) 144 (Supplement 1): 7459.

https://doi.org/10.1182/blood-2024-209270

Published: 2024

Journal Articles

Engineering FVIII Protein for Enhancing Expression and Secretion Profile to Achieve Normal Level of FVIII in Plasma Utilizing Noninvasive Transcutaneous Ultrasound Mediated Gene Delivery

Ivan Krivega, Margarita Krivega, Julia Poniatowski, David Kim, Elizabeth Del Greco, Surabhi Rao, Victor Foster, Bert Frederich, Glenda Arauz, Celia Ortiz, Oliver Chen, Tanaya Ghosh, Dhruv Bole, Katelyn N Benthall, Anagha Rao, David Satyadi, Zoya Gulzman-Poltorak, Steve Feinstein, Kenneth Greenberg

Blood (2024) 144 (Supplement 1): 7458.

https://doi.org/10.1182/blood-2024-209151

Published: 2024