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David G. Williams
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Journal Articles

ADCT-402, a PBD dimer–containing antibody drug conjugate targeting CD19-expressing malignancies

Francesca Zammarchi, Simon Corbett, Lauren Adams, Peter C. Tyrer, Konstantinos Kiakos, Narinder Janghra, Teresa Marafioti, Charles E. Britten, Carin E. G. Havenith, Simon Chivers, Francois D’Hooge, David G. Williams, Arnaud Tiberghien, Philip W. Howard, John A. Hartley, Patrick H. van Berkel
Journal: Blood
Blood (2018) 131 (10): 1094–1105.
https://doi.org/10.1182/blood-2017-10-813493
Published: 2018
Includes: Supplemental data
Journal Articles

Pre-Clinical Development of Adct-402, a Novel Pyrrolobenzodiazepine (PBD)-Based Antibody Drug Conjugate (ADC) Targeting CD19-Expressing B-Cell Malignancies

Francesca Zammarchi, PhD, David G. Williams, PhD, Lauren Adams, Karin Havenith, PhD, Simon Chivers, PhD, Francois D'Hooge, PhD, Philip W. Howard, PhD, John A. Hartley, PhD, Patrick H. van Berkel, PhD
Journal: Blood
Blood (2015) 126 (23): 1564.
https://doi.org/10.1182/blood.V126.23.1564.1564
Published: 2015
Journal Articles

Mechanistic and Pharmacodynamic Studies of Adct-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

Michael J. Flynn, MD, Patrick H. van Berkel, PhD, Francesca Zammarchi, PhD, Peter C. Tyrer, PhD, Ayse U. Akarca, Narinder Janghra, Vishvesh Shende, PhD, Joseph Linares, Teresa Marafioti, MD, David G. Williams, PhD, Philip W. Howard, PhD, John A. Hartley, PhD
Journal: Blood
Blood (2015) 126 (23): 1559.
https://doi.org/10.1182/blood.V126.23.1559.1559
Published: 2015
Journal Articles

Pre-Clinical Activity of Adct-301, a Novel Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

Michael J Flynn, MBBCh, Patrick van Berkel, PhD, Francesca Zammarchi, PhD, Jean-Noel Levy, PhD, Arnaud Tiberghien, PhD, Luke A Masterson, PhD, François D'Hooge, PhD, Lauren Adams, David G Williams, PhD, Philip W Howard, PhD, John A Hartley, PhD
Journal: Blood
Blood (2014) 124 (21): 4491.
https://doi.org/10.1182/blood.V124.21.4491.4491
Published: 2014