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Journal Articles

A phase 3 randomized trial of mavorixafor, a CXCR4 antagonist, for WHIM syndrome

Clinical Trials & Observations
Raffaele Badolato, Laia Alsina, Antoine Azar, Yves Bertrand, Audrey A. Bolyard, David Dale, Àngela Deyà-Martínez, Kathryn E. Dickerson, Navid Ezra, Henrik Hasle, Hyoung Jin Kang, Sorena Kiani-Alikhan, Taco W. Kuijpers, Alexander Kulagin, Daman Langguth, Carina Levin, Olaf Neth, Peter Olbrich, Jane Peake, Yulia Rodina, Caroline E. Rutten, Anna Shcherbina, Teresa K. Tarrant, Matthias G. Vossen, Christian A. Wysocki, Andrea Belschner, Gary J. Bridger, Kelly Chen, Susan Dubuc, Yanping Hu, Honghua Jiang, Sunny Li, Rick MacLeod, Murray Stewart, Arthur G. Taveras, Tina Yan, Jean Donadieu
Journal: Blood
Blood (2024) 144 (1): 35–45.
https://doi.org/10.1182/blood.2023022658
Published: 2024
Includes: Supplemental data
Journal Articles

The Effect of the MK0339 Neutrophil Elastase Inhibitor on Proliferation and Maturation of iPSC Derived from Patients with ELANE, TCIRG1 and Whim Syndrome Associated Neutropenia

Vahagn Makaryan, MD, Breanna Fletcher, BSc, Merideth L. Kelley, MS, David Dale, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 545.
https://doi.org/10.1182/blood.V130.Suppl_1.545.545
Published: 2017
Journal Articles

Cyclic Neutropenia, Congenital and Idiopathic Neutropenia

David Dale, MD, Audrey Anna Bolyard, RN, BS, Jamie Leung, Emily Tran, Tracy M. Marrero, Peter E. Newburger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2275.
https://doi.org/10.1182/blood.V130.Suppl_1.2275.2275
Published: 2017
Journal Articles

X4P-001: A Novel Molecularly-Targeted Oral Therapy for Whim Syndrome

David Dale, MD, Audrey Anna Bolyard, RN, BS, Emily Dick, BA, Merideth L. Kelley, MS, Vahagn Makaryan, MD, Ramsey Johnson, MSM, Lu Gan, MD PhD, Sudha Parasuraman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 995.
https://doi.org/10.1182/blood.V130.Suppl_1.995.995
Published: 2017
Journal Articles

Long-Term Outcomes for G-CSF Treatment of Patients with Glycogen-Storage Disease Type Ib

David Dale, MD, Audrey Anna Bolyard, RN, BS, Tracy M. Marrero, David A. Weinstein, MD MMSc, Cornelia Zeidler, Karl Welte
Journal: Blood
Blood (2017) 130 (Supplement 1): 996.
https://doi.org/10.1182/blood.V130.Suppl_1.996.996
Published: 2017
Journal Articles

Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis

David S. Grenda, Mark Murakami, Jhuma Ghatak, Jun Xia, Laurence A. Boxer, David Dale, Mary C. Dinauer, Daniel C. Link
Journal: Blood
Blood (2007) 110 (13): 4179–4187.
https://doi.org/10.1182/blood-2006-11-057299
Published: 2007
Includes: Supplemental data
Journal Articles

Accelerated Apoptosis and Aberrant Retention of Bone Marrow Cells in Myelokathexis Are Two Independent Pathways Triggered by Mutant CXCR4 and Normalized upon Treatment with Specific Inhibitors.

Vahagn Makaryan, MD, Oscar Penate, MD, David Dale, MD, Andrew Aprikyan, PhD
Journal: Blood
Blood (2007) 110 (11): 3300.
https://doi.org/10.1182/blood.V110.11.3300.3300
Published: 2007
Journal Articles

Granulocytic Precursors from Patients with ELA2-Mutant Severe Congenital Neutropenia Display a Transcriptional Profile Consistent with Activation of the Unfolded Protein Response.

Mark Murakami, Jun Xia, Catherine T. Jordan, Laurence A. Boxer, David Dale, Audrey A. Bolyard, Mary C. Dinauer, Daniel C. Link
Journal: Blood
Blood (2007) 110 (11): 662.
https://doi.org/10.1182/blood.V110.11.662.662
Published: 2007
Journal Articles

Small Molecule Inhibitor of Neutrophil Elastase Restores Impaired Production of Human Myeloid Cells Observed in Severe Congenital Neutropenia.

Andrew A. Aprikyan, PhD, Vahagn Makaryan, MD, Qian Si, PhD, Kelly Treonze, PhD, Nara Markosyan, BS, Paul Finke, PhD, Maxim Totrov, PhD, Ruben Abagyan, PhD, Richard Mumford, BA, David Dale, MD
Journal: Blood
Blood (2007) 110 (11): 664.
https://doi.org/10.1182/blood.V110.11.664.664
Published: 2007
Journal Articles

Allogeneic Blood Stem Cell Transplantation: Considerations for Donors

Paolo Anderlini, Martin Körbling, David Dale, Alois Gratwohl, Norbert Schmitz, David Stroncek, Craig Howe, Susan Leitman, Mary Horowitz, Eliane Gluckman, Scott Rowley, Donna Przepiorka, Richard Champlin
Journal: Blood
Blood (1997) 90 (3): 903–908.
https://doi.org/10.1182/blood.V90.3.903
Published: 1997