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Daniela S. Gerhard, Ph.D.
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Journal Articles

PIM3-SCO2 Fusion Is a Novel Transcription-Induced Chimera That Is Highly Prevalent In Childhood AML

Julia Kuhn, BA, Daoud Meerzaman, MD, Rhonda E. Ries, MA, Filippo Milano, MD, PhD, Alan S. Gamis, MD, MPH, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Malcolm A. Smith, MD, PhD, Yan Chunhua, Chih Hao Hsu, Cu Nguyen, Daniela S. Gerhard, Ph.D., Daniel Wai, Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2549.
https://doi.org/10.1182/blood.V122.21.2549.2549
Published: 2013
Journal Articles

Genome-Wide DNA Methylation Analysis Reveals Biological and Clinical Insights In Relapsed Childhood Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

Huimin Geng, PhD, Mignon L. Loh, MD, Richard C. Harvey, PhD, I-Ming Chen, DVM, Meenakshi Devidas, PhD, Tanja M. Davidsen, PhD, Jaime M. Guidry Auvil, PhD, Daniela S. Gerhard, Ph.D., Malcolm A. Smith, MD PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Julie M. Gastier-Foster, PhD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS MSc MD, Stephen P. Hunger, MD, Ari Melnick, MD
Journal: Blood
Blood (2013) 122 (21): 3736.
https://doi.org/10.1182/blood.V122.21.3736.3736
Published: 2013
Journal Articles

Comparison Of Mutational Profiles Of Diagnosis and Relapsed Pediatric B-Acute Lymphoblastic Leukemia: A Report From The COG ALL Target Project

Jinghui Zhang, PhD, Mignon L. Loh, MD, Xiaotu Ma, PhD, Michael Rusch, BA, Gang Wu, PhD, Richard C. Harvey, PhD, David A. Wheeler, PhD, Oliver A. Hampton, PhD, William L. Carroll, MD, I-Ming Chen, DVM, Daniela S. Gerhard, Ph.D., Julie M. Gastier-Foster, PhD, Mary V. Relling, PharmD, Malcolm A. Smith, MD, PhD, Meenakshi Devidas, PhD, Jaime M. Guidry Auvil, PhD, James R. Downing, MD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Stephen P. Hunger, MD
Journal: Blood
Blood (2013) 122 (21): 824.
https://doi.org/10.1182/blood.V122.21.824.824
Published: 2013
Journal Articles

Integrated Genomic and Mutational Profiling Of Adolescent and Young Adult ALL Identifies a High Frequency Of BCR-ABL1 -Like ALL with Very Poor Outcome

Kathryn G. Roberts, PhD, Debbie Payne-Turner, Deqing Pei, MS, Jared Becksfort, Richard C. Harvey, PhD, Yongjin Li, Guangchun Song, Jinjun Cheng, MD, Jing Ma, PhD, Jinghui Zhang, PhD, Cheng Cheng, PhD, Shann-Ching Chen, PhD, I-Ming L. Chen, Meenakshi Devidas, PhD, Eric C. Larsen, MD, William L. Carroll, MD, Naomi J. Winick, MD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Julie M. Gastier-Foster, PhD, Elizabeth A. Raetz, MD, Ching-Hon Pui, MD, Sima Jeha, MD, James R. Downing, MD, Elisabeth Paietta, PhD, Steven M. Kornblau, MD, Guido Marcucci, MD, Wendy Stock, MD, Clara D. Bloomfield, MD, Daniela S. Gerhard, Ph.D., Mignon L. Loh, MD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA
Journal: Blood
Blood (2013) 122 (21): 825.
https://doi.org/10.1182/blood.V122.21.825.825
Published: 2013
Journal Articles

Development and Validation Of a Highly Sensitive and Specific Gene Expression Classifier To Prospectively Screen and Identify B-Precursor Acute Lymphoblastic Leukemia (ALL) Patients With a Philadelphia Chromosome-Like (“ Ph-like ” or “ BCR-ABL1-Like ”) Signature For Therapeutic Targeting and Clinical Intervention

Richard C. Harvey, PhD, Huining Kang, PhD, Kathryn G. Roberts, PhD, I-Ming L. Chen, DVM, MS, Susan R. Atlas, PhD, Edward J. Bedrick, PhD, Julie M. Gastier-Foster, PhD, Jinghui Zhang, PhD, Daniela S. Gerhard, Ph.D., Malcolm A. Smith, MD, PhD, Eric C. Larsen, MD, Elizabeth A. Raetz, MD, Naomi J. Winick, MD, William L. Carroll, MD, Eileen Stonerock, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Shann-Ching Chen, PhD, Guangchun Song, Jared Becksfort, Michael Rusch, BA, Yongjin Li, Jing Ma, PhD, Denise Ell, Shalini C. Reshmi, PhD, Mignon L. Loh, MD, Meenakshi Davidas, PhD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Cheryl L. Willman, MD
Journal: Blood
Blood (2013) 122 (21): 826.
https://doi.org/10.1182/blood.V122.21.826.826
Published: 2013
Journal Articles

Genomic Characterization and Experimental Modeling Of BCR-ABL1 -Like Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Yongjin Li, Debbie Payne-Turner, Richard C. Harvey, PhD, Jinjun Cheng, MD, Jinghui Zhang, PhD, Guangchun Song, Yung-Li Yang, M.D, Natalia Santiago-Morales, Deqing Pei, MS, Cheng Cheng, PhD, Jing Ma, PhD, Shann-Ching Chen, PhD, Michael Rusch, BA, Pankaj Gupta, Meenakshi Devidas, PhD, I-Ming Chen, DVM, Eric C. Larsen, MD, Naomi J. Winick, MD, William L. Carroll, MD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Julie M. Gastier-Foster, PhD, Elizabeth A. Raetz, MD, Ching-Hon Pui, MD, Sima Jeha, MD, James R Downing, MD, Elisabeth Paietta, PhD, Steven M. Kornblau, MD, Guido Marcucci, MD, Clara D. Bloomfield, MD, Daniela S. Gerhard, Ph.D., Mignon L. Loh, MD, Cheryl L. Willman, MD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA
Journal: Blood
Blood (2013) 122 (21): 232.
https://doi.org/10.1182/blood.V122.21.232.232
Published: 2013
Journal Articles

Integrative Network Analysis of Pediatric AML Whole Genomes, cDNA Expression and Clinical Data Elements Reveals Shared As Well As t(8;21), Inv16 and MLL Specific Pathways; A Report From COG/NCI Target AML Initiative

Hamid Bolouri, PhD, Rhonda E. Ries, MA, Ranjani Ramamurthy, MS, Todd A. Alonzo, PhD, Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Alan S. Gamis, MD, MPH, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3519.
https://doi.org/10.1182/blood.V120.21.3519.3519
Published: 2012
Journal Articles

Clinically Significant Mutations, Deletions and Translocations Involving ETV6 Identified by Whole Genome and Whole Exome Sequencing; Report From NCI/COG Target AML Initiative

Heather L. Helton, MD, Rhonda E. Ries, MA, Todd A. Alonzo, PhD, Robert B. Gerbing, M.A., Lisa R. Trevino, PhD, Jason Farrar, M.D., Jaime M. Guidry Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, Janet Franklin, MD, MPH, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD, Soheil Meshinchi, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 125.
https://doi.org/10.1182/blood.V120.21.125.125
Published: 2012
Journal Articles

Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution From Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – an NCI/COG Target AML Study

Soheil Meshinchi, MD, PhD, Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Oliver A. Hampton, PhD, Todd Alonzo, PhD, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, PhD, Donna M. Muzny, Alan S. Gamis, MD, MPH, Heather L. Helton, MD, David A. Wheeler, PhD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Robert J. Arceci, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 123.
https://doi.org/10.1182/blood.V120.21.123.123
Published: 2012
Journal Articles

Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children

Michael Ochs, Ph.D., Jason Farrar, M.D., Michael Considine, M.S., Rhonda E. Ries, MA, Lisa R. Trevino, PhD, Todd A. Alonzo, PhD, Jaime Guidry-Auvil, Ph.D., Tanja M. Davidsen, PhD, Patee Gesuwan, Ph.D., Donna M. Muzny, Alan S. Gamis, MD, MPH, David A. Wheeler, PhD, Heather L. Helton, MD, Malcolm A. Smith, MD, PhD, Daniela S. Gerhard, Ph.D., Soheil Meshinchi, MD, PhD, Robert J. Arceci, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1287.
https://doi.org/10.1182/blood.V120.21.1287.1287
Published: 2012
Journal Articles

Novel Chromosomal Rearrangements and Sequence Mutations in High-Risk Ph-Like Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Ryan D Morin, M.Sc., Jinghui Zhang, PhD, Martin Hirst, Ph.D., Richard C. Harvey, PhD, Corynn Kasap, BS, Xiang Chen, PhD, Michael Edmonson, Ph.D., I-Ming Chen, DVM, MS, Neil Shah, MD, PhD, Meenakshi Devidas, PhD, Gregory H. Reaman, MD, Malcolm A. Smith, MD, PhD, Ching-Hon Pui, MD, James R. Downing, MD, Daniela S Gerhard, Ph.D., Cheryl L Willman, MD, Mignon L Loh, MD, Stephen P Hunger, MD, Marco A. Marra, PhD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc
Journal: Blood
Blood (2011) 118 (21): 67.
https://doi.org/10.1182/blood.V118.21.67.67
Published: 2011
Journal Articles

Lack of Somatic Sequence Mutations In Protein Tyrosine Kinase Genes Other Than the JAK Kinase Family In High Risk B-Precursor Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) High-Risk (HR) ALL TARGET Project

Jinghui Zhang, Ph.D., Charles Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Richard Harvey, PhD, William L. Carroll, MD, I-Ming L. Chen, DVM, MS, Meenakshi Devidas, PhD, Eric Larsen, Michael Edmonson, Ph.D., Ken Buetow, Ph.D., Daniela S Gerhard, Ph.D., Mignon L. Loh, M.D., Gregory H. Reaman, MD, Mary V. Relling, PharmD, Malcolm A Smith, M.D., Ph.D., James R. Downing, MD, Cheryl L. Willman, MD, Stephen Hunger, MD
Journal: Blood
Blood (2010) 116 (21): 2752.
https://doi.org/10.1182/blood.V116.21.2752.2752
Published: 2010
Journal Articles

Deletion of IKZF1 (Ikaros) Predicts Poor Outcome and Impaired Maturation in B-Progenitor Acute Lymphoblastic Leukemia

Charles G. Mullighan, MBBS(Hons), MSc, MD, Xiaoping Su, PhD, Jinghui Zhang, PhD, Ina Radtke, PhD, Letha A Phillips, BS, Christopher B Miller, BS, Jing Ma, PhD, Wei Liu, PhD, Cheng Cheng, PhD, Richard C. Harvey, PhD, I-Ming Chen, DVM, MS, Robert Clifford, PhD, William L. Carroll, MD, Gregory Reaman, MD, Meenakshi Devidas, PhD, Daniela S. Gerhard, Ph.D., Wenjian Yang, PhD, W. Paul Bowman, Sheila A. Shurtleff, PhD, Mary V. Relling, PharmD, Malcolm Smith, MD, PhD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, James R. Downing, MD
Journal: Blood
Blood (2008) 112 (11): 427.
https://doi.org/10.1182/blood.V112.11.427.427
Published: 2008