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Journal Articles

Anti-Leukemic Efficacy of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies

Vanessa Kohl, MSc, Susanne Brendel, MTA, Johanna Flach, PhD, Helga Kleiner, MTA, Christel Weiss, PhD, Wolfgang Seifarth, PhD, Daniel Nowak, MD, Wolf-Karsten Hofmann, MD PhD, Alice Fabarius, PhD, Henning D. Popp

Blood (2019) 134 (Supplement_1): 5056.

https://doi.org/10.1182/blood-2019-122672

Published: 2019

Journal Articles

Comparison of Four Different Humanized Hematopoietic Niche Xenotransplantation Methods to Engraft Myelodysplastic Syndromes (MDS)

Blood (2019) 134 (Supplement_1): 4227.

https://doi.org/10.1182/blood-2019-128075

Published: 2019

Journal Articles

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Johann-Christoph Jann, Johanna Flach, PhD, Antje Knaflic, Eva Altrock, PhD, Nanni Schmitt, MSc, Alexander Streuer, Justine Danner, Franziska Hofmann, Verena Nowak, Nina Draeger, Julia Obländer, Iris Palme, Patrick Wuchter, MD, Ahmed Jawhar, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, MD PhD, Daniel Nowak, MD

Blood (2019) 134 (Supplement_1): 4218.

https://doi.org/10.1182/blood-2019-126431

Published: 2019

Journal Articles

Placebo Controlled Functional Analysis of Eltrombopag in a Preclinical Xenograft Model of Myelodysplastic Syndromes (MDS)

Nanni Schmitt, MSc, Eva Altrock, PhD, Johann-Christoph Jann, MD, Johanna Flach, PhD, Carla Sens-Albert, PhD, Justine Danner, Stefanie Uhlig, Jovita Pressler, Iris Palme, Verena Nowak, Julia Obländer, Lena Drangmeister, MD, Franziska La Meir, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, Daniel Nowak, MD

Blood (2018) 132 (Supplement 1): 942.

https://doi.org/10.1182/blood-2018-99-116341

Published: 2018

Journal Articles

Safety and Efficacy of the CD95-Ligand Inhibitor APG101 in Transfusion-Dependent Patients with Low Risk MDS: Results from a Phase I Study

Tobias Boch, MD, Thomas Luft, MD PhD, Maximilian Mossner, Johann-Christoph Jann, Daniel Nowak, MD, Christine Folz, Jennifer Klemmer, Susanne Brendel, Harald Fricke, MD, Claudia Kunz, PhD, Wolf-Karsten Hofmann, MD, Florian Nolte, MD

Blood (2016) 128 (22): 228.

https://doi.org/10.1182/blood.V128.22.228.228

Published: 2016

Journal Articles

Validation of a Molecular Risk Score for Prognosis of Patients with Acute Promyelocytic Leukemia

Anna Hecht, MD, Seraphina Doll, Heidi Schaarschmidt, Daniel Nowak, MD, Verena Nowak, Julia Obländer, Christina Xanthopoulos, Eva Lengfelder, MD, Christoph Röllig, MD, Gerhard Ehninger, MD, Wolf-Karsten Hofmann, MD, Uwe Platzbecker

Blood (2016) 128 (22): 1668.

https://doi.org/10.1182/blood.V128.22.1668.1668

Published: 2016

Journal Articles

RNA Sequencing of Bone Marrow Derived Mesenchymal Stromal Cells (MSCs) of Healthy Young, Healthy Old and Patients with Myelodysplastic Syndrome (MDS) Reveals Transcriptomic Changes upon Aging of the Niche and Onset of MDS

Johann-Christoph Jann, Maximilian Mossner, Florian Nolte, MD, Tobias Boch, MD, Verena Nowak, Iris Palme, Julia Obländer, Jovita Pressler, Christina Xanthopoulos, Henning Röhl, MD, Wolf-Karsten Hofmann, MD, Daniel Nowak, MD

Blood (2016) 128 (22): 4300.

https://doi.org/10.1182/blood.V128.22.4300.4300

Published: 2016

Journal Articles

Application of a Short Tandem Repeat Based PCR Assay for Chronological Monitoring of Myelodysplastic Syndrome (MDS) Patients with Deletion of Chromosome 5q Following Lenalidomide Treatment

Blood (2015) 126 (23): 2891.

https://doi.org/10.1182/blood.V126.23.2891.2891

Published: 2015

Journal Articles

Erythroferrone (ERFE) Is Selectively Expressed in Human CD71+ Erythroprogenitor Cells and Deregulated Overexpression Is Associated with a Favorable Outcome in Low Risk Myelodysplastic Syndrome (MDS)

Maximilian Mossner, Alexandra Stoehr, Johann-Christoph Jann, Florian Nolte, MD, Verena Nowak, Julia Oblaender, Jovita Pressler, Christina Xanthopoulos, Iris Palme, Claudia D Baldus, MD, Torsten Schulze, MD, Tobias Boch, MD, Georgia Metzgeroth, MD, Martin Neumann, MD, Wolf-Karsten Hofmann, MD, Daniel Nowak, MD

Blood (2015) 126 (23): 2859.

https://doi.org/10.1182/blood.V126.23.2859.2859

Published: 2015

Journal Articles

Whole Genome Sequencing of Azole-Resistant Aspergillus Fumigatus Strains from Hematopoietic Stem Cell Recipients Identifies Candidate Molecular Targets Potentially Implicated in Novel Resistance Mediating Mechanisms - First Results

Maximilian Mossner, Birgit Spiess, PhD, Johann-Christoph Jann, Verena Nowak, Julia Obländer, Oliver Bader, Wolf-Karsten Hofmann, MD, Daniel Nowak, MD, Dieter Buchheidt, MD, Tobias Boch, MD

Blood (2015) 126 (23): 4325.

https://doi.org/10.1182/blood.V126.23.4325.4325

Published: 2015

Journal Articles

Different Impact of Expression Levels of IGFBP2 and IGFBP7 on Survival and Relapse Rate in Acute Promyelocytic Leukemia

Anna Hecht, Daniel Nowak, MD, Florian Nolte, Verena Nowak, Julia Oblaender, Thomas Buechner, Karsten Spiekermann, Wolf-Karsten Hofmann, MD, Eva Lengfelder, MD

Blood (2015) 126 (23): 1382.

https://doi.org/10.1182/blood.V126.23.1382.1382

Published: 2015

Journal Articles

Next Generation RNA Sequencing of Acute Promyelocytic Leukemia (APL) Identifies Novel Long Non Coding RNAs Including New Variants of MIR181A1HG That Are Differentially Expressed during Myeloid Differentiation

Frederic Lammer, Marion Klaumuenzer, PhD, Maximilian Mossner, Johann Christoph Jann, Anna Hecht, MD, Verena Nowak, Stephanie Fey, Julia Oblaender, Jovita Pressler, Eva Lengfelder, MD, Wolf-Karsten Hofmann, MD PhD, Daniel Nowak, MD

Blood (2014) 124 (21): 1031.

https://doi.org/10.1182/blood.V124.21.1031.1031

Published: 2014

Journal Articles

Molecular Characterization Of The Anti-Leukemic Effects Of Single Agent Eltrombopag

Uwe Platzbecker, MD, PhD, Katja Sockel, MD, Claudia Schönefeldt, Daniel Nowak, MD, Susann Helas, PhD, Christoph Röllig, MD, Maximilian Mossner, Johann-Christoph Jann, Gerhard Ehninger, MD, Wolf-Karsten Hofmann, MD, Martin Bornhäuser, MD, Christian Thiede, MD, Martin Wermke, MD

Blood (2013) 122 (21): 4923.

https://doi.org/10.1182/blood.V122.21.4923.4923

Published: 2013

Journal Articles

Array-Based Integrative Analysis Of Epigenomic and Transcriptomic Alterations In CD71+ Bone Marrow Erythroprogenitor Cells From Patients With Myelodysplastic Syndromes

Maximilian Mossner, Axel Wilbertz, Stephanie Fey, Julia Obländer, Verena Nowak, Jovita Vogler, Florian Nolte, MD, Ralf Bieber, Wolf-Karsten Hofmann, MD, Mark Reinwald, MD, Daniel Nowak, MD

Blood (2013) 122 (21): 1561.

https://doi.org/10.1182/blood.V122.21.1561.1561

Published: 2013

Journal Articles

The New CD95 Ligand Inhibitor APG101 Leads To Decreased Apoptosis and Improved Erythroid Differentiation In Primary CD34+ Cells From Patients With Low Risk Myelodysplastic Syndrome (MDS)

Florian Nolte, MD, Claudia Kunz, Stephanie Fey, Julia Obländer, Susanne Brendel, Marion Klaumünzer, Maximilian Mossner, Johann-Christoph Jann, Stefanie Uhlig, Daniel Nowak, MD, Harald Fricke, MD, Wolf-Karsten Hofmann, MD

Blood (2013) 122 (21): 1562.

https://doi.org/10.1182/blood.V122.21.1562.1562

Published: 2013

Journal Articles

TP53 Mutations Detected By Next-Generation Deep-Sequencing In Patients With Myelodysplastic Syndrome and Isolated Deletion (5q): Results From a German Multicenter Trial

Blood (2013) 122 (21): 2759.

https://doi.org/10.1182/blood.V122.21.2759.2759

Published: 2013

Journal Articles

MDS-Derived Stromal Cells Exhibit Altered Gene Expression and Support The Engraftment Of lin - CD34 + CD38 - Disease-Initiating Stem Cells In a Xenograft Model Of Lower Risk MDS

Blood (2013) 122 (21): 100.

https://doi.org/10.1182/blood.V122.21.100.100

Published: 2013

Journal Articles

A Risk Score Integrating BAALC, ERG and WT1 Expression Can Be Used To Improve Risk Stratification In Acute Promyelocytic Leukemia

Anna Hecht, Florian Nolte, MD, Daniel Nowak, MD, Verena Nowak, Benjamin Hanfstein, MD, Thomas Büchner, MD, Karsten Spiekermann, MD, Wolf-Karsten Hofmann, MD, Eva Lengfelder, MD

Blood (2013) 122 (21): 1323.

https://doi.org/10.1182/blood.V122.21.1323.1323

Published: 2013

Journal Articles

In Adult Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia, The Negative Prognostic Impact Of IKZF1, CDKN2A/B and PAX5 Deletions Is Not Abrogated By Allogeneic Stem Cell Transplantation In First Complete Remission

Heike Pfeifer, MD, Katharina Raum, Sandra Markovic, Stephanie Fey, Julia Obländer, Verena Nowak, Wunderle Lydia, MD, Fabian Lang, MD, Dieter Hoelzer, MD, Wolf-Karsten Hofmann, MD, Nicola Goekbuget, MD, Oliver G. Ottmann, MD, Daniel Nowak, MD

Blood (2013) 122 (21): 231.

https://doi.org/10.1182/blood.V122.21.231.231

Published: 2013

Journal Articles

Next Generation Sequencing-Based Molecular Dissection Of Lineage-Specific Mutational Hierarchies In Oligoclonal Primary and Xenografted Myelodysplasia

Johann-Christoph Jann, Daniel Nowak, MD, Florian Nolte, MD, Claudia Haferlach, MD, Marita Staller, Verena Nowak, Bettina Zens, Katja Müdder, Corinna Klein, Julia Obländer, Stephanie Fey, Jovita Vogler, Alice Fabarius, PhD, Alexander Kohlmann, PhD, Wolf-Karsten Hofmann, MD, Andreas Trumpp, PhD, Hind Medyouf, PhD, Maximilian Mossner

Blood (2013) 122 (21): 519.

https://doi.org/10.1182/blood.V122.21.519.519

Published: 2013

NARROW

Anti-Leukemic Efficacy of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies

Comparison of Four Different Humanized Hematopoietic Niche Xenotransplantation Methods to Engraft Myelodysplastic Syndromes (MDS)

R-Loops-Induced ATR Signaling As a Potential Therapeutic Target in Myelodysplastic Syndrome

Placebo Controlled Functional Analysis of Eltrombopag in a Preclinical Xenograft Model of Myelodysplastic Syndromes (MDS)

Safety and Efficacy of the CD95-Ligand Inhibitor APG101 in Transfusion-Dependent Patients with Low Risk MDS: Results from a Phase I Study

Validation of a Molecular Risk Score for Prognosis of Patients with Acute Promyelocytic Leukemia

RNA Sequencing of Bone Marrow Derived Mesenchymal Stromal Cells (MSCs) of Healthy Young, Healthy Old and Patients with Myelodysplastic Syndrome (MDS) Reveals Transcriptomic Changes upon Aging of the Niche and Onset of MDS

Application of a Short Tandem Repeat Based PCR Assay for Chronological Monitoring of Myelodysplastic Syndrome (MDS) Patients with Deletion of Chromosome 5q Following Lenalidomide Treatment

Erythroferrone (ERFE) Is Selectively Expressed in Human CD71+ Erythroprogenitor Cells and Deregulated Overexpression Is Associated with a Favorable Outcome in Low Risk Myelodysplastic Syndrome (MDS)

Whole Genome Sequencing of Azole-Resistant Aspergillus Fumigatus Strains from Hematopoietic Stem Cell Recipients Identifies Candidate Molecular Targets Potentially Implicated in Novel Resistance Mediating Mechanisms - First Results

Different Impact of Expression Levels of IGFBP2 and IGFBP7 on Survival and Relapse Rate in Acute Promyelocytic Leukemia

Next Generation RNA Sequencing of Acute Promyelocytic Leukemia (APL) Identifies Novel Long Non Coding RNAs Including New Variants of MIR181A1HG That Are Differentially Expressed during Myeloid Differentiation

Molecular Characterization Of The Anti-Leukemic Effects Of Single Agent Eltrombopag

Array-Based Integrative Analysis Of Epigenomic and Transcriptomic Alterations In CD71+ Bone Marrow Erythroprogenitor Cells From Patients With Myelodysplastic Syndromes

The New CD95 Ligand Inhibitor APG101 Leads To Decreased Apoptosis and Improved Erythroid Differentiation In Primary CD34+ Cells From Patients With Low Risk Myelodysplastic Syndrome (MDS)

TP53 Mutations Detected By Next-Generation Deep-Sequencing In Patients With Myelodysplastic Syndrome and Isolated Deletion (5q): Results From a German Multicenter Trial

MDS-Derived Stromal Cells Exhibit Altered Gene Expression and Support The Engraftment Of lin - CD34 + CD38 - Disease-Initiating Stem Cells In a Xenograft Model Of Lower Risk MDS

A Risk Score Integrating BAALC, ERG and WT1 Expression Can Be Used To Improve Risk Stratification In Acute Promyelocytic Leukemia

In Adult Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia, The Negative Prognostic Impact Of IKZF1, CDKN2A/B and PAX5 Deletions Is Not Abrogated By Allogeneic Stem Cell Transplantation In First Complete Remission

Next Generation Sequencing-Based Molecular Dissection Of Lineage-Specific Mutational Hierarchies In Oligoclonal Primary and Xenografted Myelodysplasia

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American Society of Hematology

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American Society of Hematology

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