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DR Higgs
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Journal Articles

Targeted inactivation of the major positive regulatory element (HS-40) of the human alpha-globin gene locus

A Bernet, S Sabatier, DJ Picketts, R Ouazana, F Morle, DR Higgs, J Godet
Journal: Blood
Blood (1995) 86 (3): 1202–1211.
https://doi.org/10.1182/blood.V86.3.1202.1202
Published: 1995
Journal Articles

The mouse alpha-globin locus regulatory element

G Gourdon, JA Sharpe, DR Higgs, WG Wood
Journal: Blood
Blood (1995) 86 (2): 766–775.
https://doi.org/10.1182/blood.V86.2.766.bloodjournal862766
Published: 1995
Journal Articles

Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression

JA Sharpe, RJ Summerhill, P Vyas, G Gourdon, DR Higgs, WG Wood
Journal: Blood
Blood (1993) 82 (5): 1666–1671.
https://doi.org/10.1182/blood.V82.5.1666.1666
Published: 1993
Journal Articles

Regulation of human embryonic globin genes zeta 2 and epsilon in stably transformed mouse erythroleukemia cells

P Vyas, JA Sharpe, P Watt, DR Higgs, WG Wood
Journal: Blood
Blood (1992) 80 (7): 1832–1837.
https://doi.org/10.1182/blood.V80.7.1832.1832
Published: 1992
Journal Articles

Human embryonic zeta-globin chain expression in deletional alpha- thalassemias

W Tang, HY Luo, M Albitar, M Patterson, B Eng, JS Waye, SA Liebhaber, DR Higgs, DH Chui
Journal: Blood
Blood (1992) 80 (2): 517–522.
https://doi.org/10.1182/blood.V80.2.517.517
Published: 1992
Journal Articles

Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes

L Romao, L Osorio-Almeida, DR Higgs, J Lavinha, SA Liebhaber
Journal: Blood
Blood (1991) 78 (6): 1589–1595.
https://doi.org/10.1182/blood.V78.6.1589.1589
Published: 1991
Journal Articles

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster

CS Hatton, AO Wilkie, HC Drysdale, WG Wood, MA Vickers, J Sharpe, H Ayyub, IM Pretorius, VJ Buckle, DR Higgs
Journal: Blood
Blood (1990) 76 (1): 221–227.
https://doi.org/10.1182/blood.V76.1.221.221
Published: 1990
Journal Articles

Human embryonic zeta-globin chains in fetal and newborn blood

DH Chui, WC Mentzer, M Patterson, TA Iarocci, SH Embury, SP Perrine, RS Mibashan, DR Higgs
Journal: Blood
Blood (1989) 74 (4): 1409–1414.
https://doi.org/10.1182/blood.V74.4.1409.1409
Published: 1989
Journal Articles

A review of the molecular genetics of the human alpha-globin gene cluster

DR Higgs, MA Vickers, AO Wilkie, IM Pretorius, AP Jarman, DJ Weatherall
Journal: Blood
Blood (1989) 73 (5): 1081–1104.
https://doi.org/10.1182/blood.V73.5.1081.1081
Published: 1989
Journal Articles

The polyadenylation site mutation in the alpha-globin gene cluster

SL Thein, RB Wallace, L Pressley, JB Clegg, DJ Weatherall, DR Higgs
Journal: Blood
Blood (1988) 71 (2): 313–319.
https://doi.org/10.1182/blood.V71.2.313.313
Published: 1988
Journal Articles

The cellular basis for different fetal hemoglobin levels among sickle cell individuals with two, three, and four alpha-globin genes

GJ Dover, VT Chang, SH Boyer, GR Serjeant, S Antonarakis, DR Higgs
Journal: Blood
Blood (1987) 69 (1): 341–344.
https://doi.org/10.1182/blood.V69.1.341.341
Published: 1987
Journal Articles

Alpha thalassemia and the hematology of homozygous sickle cell disease in childhood

MC Stevens, GH Maude, M Beckford, Y Grandison, K Mason, B Taylor, BE Serjeant, DR Higgs, H Teal, DJ Weatherall
Journal: Blood
Blood (1986) 67 (2): 411–414.
https://doi.org/10.1182/blood.V67.2.411.411
Published: 1986
Journal Articles

Alpha zero-thalassemia due to recombination between the alpha 1-globin gene and an AluI repeat

RD Nicholls, DR Higgs, JB Clegg, DJ Weatherall
Journal: Blood
Blood (1985) 65 (6): 1434–1438.
https://doi.org/10.1182/blood.V65.6.1434.bloodjournal6561434
Published: 1985