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Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Sara Rodríguez, PhD, Cirino Botta, MDPhD, Jon Celay, PhD, Ibai Goicoechea, PhD, Cristina Jiménez, PhD, Maria J Garcia-Barchino, PhD, Rafael Valdés-Mas, Yolanda Carrasco, Juan José Garcés, Marta Larrayoz, PhD, Susana Santos, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Cristina Pérez Ruiz, Sonia Garate, Sarvide Sarai, Aitziber Lopez Lopez, Christian Reinhardt, MD, Isidro Sanchez-Garcia, PhD, Maria Jose Larrayoz, BSc, María José Calasanz, PhD, Felipe Prosper, MD, Marina Motta, MD, Giuseppe Rossi, MD, Antonio Sacco, RN, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, MD PhD, Artur Paiva, Ramón Garcia-Sanz, MD PhD, Aldo M. Roccaro, MDPhD, Jesus F. San-Miguel, MD PhD, Jose Angel Martinez-Climent, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-136982
Published: 2020
Journal Articles

Characterization of B-Cell and Plasma Cell Compartment By Eight-Color Multiparameter Flow Cytometry in Patients with Waldenstrom Macroglobulinemia Prospectively Enrolled in the Fondazione Italiana Linfomi (FIL) BIO-WM Trial

Marzia Varettoni, Simone Ferrero, MD, Cristina Picone, Milena Gilestro, Noemí Puig, MD PhD, Luigi Marcheselli, Irene Dogliotti, MD, Angela Ferrari, Michele Merli, MD, Giulia Zamprogna, MD, Luca Laurenti, MD, Simona Tomassetti, MD, Emanuele Cencini, MD, Giacomo Loseto, MD, Dario Marino, MDPhD, Monia Marchetti, MD, Francesca Re, MD, Antonello Sica, MD, Jacopo Olivieri, Cristina Jiménez, PhD, Silvia Zibellini, PhD, Daniela Drandi, PhD, Chiara Candido, Martina Ferrante, PhD, Nicole Fabbri, Federica Cavallo, Luca Arcaini, Mario Boccadoro, Ramon Garcia-Sanz
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-137119
Published: 2020
Journal Articles

A Novel HCK and BTK Dual Inhibitor Kin-8194 Shows Superior Activity over Ibrutinib and Overcomes BTK C481S Mediated Ibrutinib Resistance in Vitro and In Vivo in MYD88 Mutated B-Cell Lymphomas

Guang Yang, PhD, Jinhua Wang, PhD, Xia Liu, MD, Manit Munshi, MS, Jiaji G Chen, Amanda Kofides, Lian Xu, MS, Nicholas Tsakmaklis, Maria Demos, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Cristina Jimenez, PhD, Zachary R Hunter, PhD, Christopher Patterson, Jorge J. Castillo, MD, Sara J Buhrlage, PhD, Nathanael Gray, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 394.
https://doi.org/10.1182/blood-2019-130636
Published: 2019
Journal Articles

IgM-Gammopathies Transformed into Aggressive Lymphoma: Incidence, Basal Clinical Features and Outcome of a Registry Based, Spanish Retrospective Series

Irene Dogliotti, MD, Cristina Jiménez, PhD, Federica Cavallo, MD PhD, Noemi Puig, MD PhD, Gian Maria Zaccaria, PhD, Veronica Gonzalez De La Calle, MD PhD, Maria Eugenia Sarasquete, PhD, Miguel Alcoceba, Pilar Delgado, MD, Maria Rosa López, MD, Aránzazu García Mateo, PhD, Simone Ferrero, MD, Mario Boccadoro, Marcos González, Ramón García-Sanz, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4011.
https://doi.org/10.1182/blood-2019-123353
Published: 2019
Journal Articles

Mutated MYD88 Regulates HCK Pro-Survival Signaling through JunB in MYD88 Mutated B-Lymphoma Cells

Xia Liu, MD, Jiaji G Chen, Manit Munshi, MS, Lian Xu, MS, Amanda Kofides, Nicholas Tsakmaklis, Maria Demos, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Cristina Jimenez, PhD, Zachary R Hunter, PhD, Christopher Patterson, Kirsten Meid, MPH, Andrew Keezer, BS, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Guang Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3778.
https://doi.org/10.1182/blood-2019-130885
Published: 2019
Journal Articles

VDJH Gene Repertoire Analysis in Multiple Myeloma (MM) Patients: Correlation with Clinical Data

Alejandro Medina, Cristina Jiménez, PhD, Maria E Sarasquete, PhD, Noemi Puig, MD PhD, Ana Balanzategui, Miguel Alcoceba, PhD, Veronica Gonzalez De La Calle, MD PhD, Maria Garcia-Alvarez, B.Sc., Isabel Prieto-Conde, PhD, Carmen Chillon, PhD, Enrique M. Ocio, MD, Norma C. Gutierrez, MD PhD, Maria-Victoria Mateos, MD PhD, Joaquin Martínez-López, MD PhD, Juan Jose Lahuerta, MD PhD, Jesús F San-Miguel, MD, Marcos González, MD PhD, Ramon García-Sanz, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4446.
https://doi.org/10.1182/blood-2018-99-114627
Published: 2018
Journal Articles

Comprehensive Integration of Whole Genome, Transcriptome and Methylation Profiling Reveals Novel Gene Dysregulation Including IL15, SOCS6 and CARD11 Associated with MYD88 and CXCR4 Genotype Status in WM

Zachary R Hunter, PhD, Gloria G Chan, MS, Cristina Jimenez, PhD, Nickolas Tsakmaklis, Lian Xu, MS, Jiaji G Chen, Maria Demos, Amanda Kofides, Manit Munshi, MS, Maria Luisa Guerrera, MD, Xia Liu, MD, Guang Yang, PhD, Jorge J. Castillo, MD, Ari M Melnick, MD, Steven P Treon, MD PhD FRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 1563.
https://doi.org/10.1182/blood-2018-99-119828
Published: 2018
Journal Articles

Alternative Mutations and Isoform Dysregulation in MYD88 in Waldenstrom's Macroglobulinemia

Amanda Kofides, Maria Demos, Nickolas Tsakmaklis, Lian Xu, MS, Xia Liu, MD, Christopher Patterson, Maria Luisa Guerrera, MD, Manit Munshi, MS, Guang Yang, PhD, Jiaji G Chen, Cristina Jimenez, PhD, Gloria G Chan, MS, Joshua Gustine, MPH, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Zachary R Hunter, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1566.
https://doi.org/10.1182/blood-2018-99-119419
Published: 2018
Journal Articles

Genomic Analysis of Ibrutinib Resistance in Waldenstrom Macroglobulinemia

Cristina Jimenez, PhD, Gloria G Chan, MS, Lian Xu, MS, Nickolas Tsakmaklis, Jiaji G Chen, Maria Demos, Amanda Kofides, Maria Luisa Guerrera, MD, Xia Liu, MD, Manit Munshi, MS, Joshua Gustine, MPH, Guang Yang, PhD, Jorge J. Castillo, MD, Steven P Treon, MD PhD FRCP, Zachary R Hunter, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1372.
https://doi.org/10.1182/blood-2018-99-118819
Published: 2018
Journal Articles

New Alternatives for the Evaluation of Minimal Residual Disease (MRD) Detection By Next Generation Sequencing in Multiple Myeloma

Alejandro Medina, BSc, Cristina Jiménez, PhD, Noemi Puig, MD PhD, Beatriz Sanchez-Vega, Juan Flores-Montero, Marcos González, MD, Maria Jose Calasanz, BSc, PhD, Rosa M. Ayala, MD PhD, Maria E Sarasquete, PhD, Bruno Paiva, PhD, Maria Teresa Cedena, Marta Fernández-Mercado, Inmaculada Rapado, Laura Rosinol, MD PhD, Enrique M. Ocio, MDPhD, Albert Oriol, MD, Miguel Alcoceba, PhD, Miguel T Hernández, Rafael Martinez Martinez, Maria-Victoria Mateos, MD, Juan-José Lahuerta, Joan Bladé, MD PhD, Alberto Orfao, MD PhD, Jesus F. San Miguel, MD, Joaquin Martínez-López, Ramón García-Sanz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1783.
https://doi.org/10.1182/blood.V130.Suppl_1.1783.1783
Published: 2017