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Journal Articles

Individualized, PK-Guided Dosing of Hydroxyurea for Young Children with Sickle Cell Anemia: Final Results from the Hydroxyurea Optimization through Precision Study (HOPS)

Abena Appiah-Kubi, Seethal A Jacob, Matthew M. Heeney, Connie M. Piccone, Omar Niss, Charles T. Quinn, Stephanie A. Fritch Lilla, Maa-Ohui Quarmyne, Angeli Rampersad, Allison Remiker, Amy Tang, Min Dong, Kathryn McElhinney, Joshua R. Tanzer, Patrick T. McGann

Blood (2024) 144 (Supplement 1): 175.

https://doi.org/10.1182/blood-2024-200426

Published: 2024

Journal Articles

Individualized, PK-Guided Dosing of Hydroxyurea Is Not Associated with Increased Hematologic Toxicity Compared to Weight-Based Initial Dosing: Interim Results from the Hops Trial

Abena Appiah-Kubi, Seethal A Jacob, Matthew M. Heeney, Clark Brown, Susan E. Creary, Christine R Hollenkamp, Emily Riehm Meier, Omar Niss, Connie M. Piccone, Maa-Ohui Quarmyne, Charles T. Quinn, Allison Remiker, Kay L Saving, Min Dong, Patrick T. McGann

Blood (2022) 140 (Supplement 1): 5416–5417.

https://doi.org/10.1182/blood-2022-158623

Published: 2022

Journal Articles

Addressing Recruitment Challenges in the Engage-HU Trial in Young Children with Sickle Cell Disease

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-141471

Published: 2020

Journal Articles

An Analysis of Racial and Ethnic Backgrounds within the Casire International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research

Blood (2019) 134 (Supplement_1): 2305.

https://doi.org/10.1182/blood-2019-127613

Published: 2019

Journal Articles

International Multi-Site Clinical Validation of Point-of-Care Microchip Electrophoresis Test for Hemoglobin Variant Identification

Blood (2019) 134 (Supplement_1): 3373.

https://doi.org/10.1182/blood-2019-129336

Published: 2019

Journal Articles

Clinical Practice Patterns for Hydroxyurea Initiation in Young Children with Sickle Cell Disease

Anna M Hood, PhD, Yolanda Johnson, MLS, Cara Nwankwo, BA, Lisa M Shook, MA, Aimee K Hildenbrand, PhD, Allison A. King, MD MPH, PhD, Kim Smith-Whitley, MD, Sherif M. Badawy, MD, Alexis A Thompson, MD MPH, Susan E Creary, MD, Connie M. Piccone, MD, Lynne D. Neumayr, Jean L. Raphael, MD MPH, Amber M Yates, MD, Sohail Rana, MD, Steven K Reader, PhD, Emily Riehm Meier, MD MSHS, Amy Sobota, MD MPH, Lori E. Crosby, PhD

Blood (2019) 134 (Supplement_1): 4713.

https://doi.org/10.1182/blood-2019-124835

Published: 2019

Journal Articles

Initial Results from a Cohort in a Phase 2a Study (GBT440-007) Evaluating Adolescents with Sickle Cell Disease Treated with Multiple Doses of GBT440, a HbS Polymerization Inhibitor

Carolyn C Hoppe, MD, Adlette C. Inati, MD, Clark Brown, MD PhD, Winfred Wang, MD, Victor R. Gordeuk, MD, Robert Liem, MD, Gerald Woods, MD, Connie M. Piccone, MD, Erica Fong, Ganesh Balaratnam, MD, Sandy Dixon, Margaret E Tonda, PharmD, Carla B Washington, PhD, Yifah Yaron, MD PhD, Josh Lehrer, MD MPhil, FACC

Blood (2017) 130 (Supplement 1): 689.

https://doi.org/10.1182/blood.V130.Suppl_1.689.689

Published: 2017

Journal Articles

Pediatric Hematologists' Clinical Practices and Perspectives of Hematopoietic Cell Transplantation As a Treatment Option for Sickle Cell Disease

Alicia M Stallings, BA, Navneet S. Majhail, MD MS, Amy S Nowacki, PhD, Grace I. Onimoe, MD, Rabi Hanna, MD, Connie M. Piccone, MD

Blood (2016) 128 (22): 3532.

https://doi.org/10.1182/blood.V128.22.3532.3532

Published: 2016

Journal Articles

History of Asthma is Associated with Albuminuria within an International Pediatric Cohort of Sickle Cell Disease Patients: A Casire Group Analysis

Immacolata Tartaglione, MD, Baba PD Inusa, MBBS, FMCPaed, FRCPCH, MRCP, DCP, Raffaella Colombatti, MD PhD, Deepa Manwani, MD, Silverio Perrotta, Eugenia Vicky Naa Kwarley Asare, MBChB, BSc, Connie M. Piccone, MD, Fredericka Sey, MB ChB, Charles Antwi-Boasiako, PhD, Laura Sainati, MD, Adetola A. Kassim, MD MS, Donna Boruchov, MD, Angela Rivers, MD PhD, William Zempsky, MD, Crawford John Strunk, MD, Biree Andemariam, MD, Andrew D. Campbell, MD

Blood (2016) 128 (22): 3668.

https://doi.org/10.1182/blood.V128.22.3668.3668

Published: 2016

Journal Articles

Parent and Guardian Knowledge of Hematopoietic Cell Transplantation As a Treatment Option for Sickle Cell Disease

Alicia M Stallings, BA, Navneet S. Majhail, MD MS, Amy S Nowacki, PhD, Grace I. Onimoe, MD, Rabi Hanna, MD, Jillian Wen, B.S., Charles T Quinn, MD, Lewis L. Hsu, MD PhD, Connie M. Piccone, MD

Blood (2016) 128 (22): 1307.

https://doi.org/10.1182/blood.V128.22.1307.1307

Published: 2016

Journal Articles

Agreement Between R2 and R2* Liver Iron Estimates Is Independent of the Type of Iron Removal Therapy: Results from the Twitch Trial

John C Wood, MD PhD, Tim St Pierre, PhD, Banu Aygun, MD, Nicole Mortier, PA-C, William H Schultz, MHS PA, Connie M. Piccone, MD, Jane Hankins, MD MS, Zora R. Rogers, MD, William Owen, MD, Isaac Odame, MBChB, FRCPath, FRCPC, Sharada A. Sarnaik, MD, Lee Hilliard, MD, Alan R. Cohen, MD, Russell E. Ware, MD PhD

Blood (2016) 128 (22): 1274.

https://doi.org/10.1182/blood.V128.22.1274.1274

Published: 2016

Journal Articles

Point-of-Care Screening for Sickle Cell Disease By a Mobile Micro-Electrophoresis Platform

Ryan Ung, Yunus Alapan, MS, Muhammad Noman Hasan, MS, Megan Romelfanger, Ping He, MDPhD, Aaron Tam, Tolulope Rosanwo, BA, Asya Akkus, Mehmet A Cakar, Kutay Icoz, PhD, Connie M. Piccone, MD, Jane A Little, MD, Umut A Gurkan, PhD

Blood (2015) 126 (23): 3379.

https://doi.org/10.1182/blood.V126.23.3379.3379

Published: 2015

Journal Articles

Acute Care in the Emergency Department Differs before and after Transition for Adolescents and Young Adults with Sickle Cell Disease

Nathan R. Stehouwer, MD, Bohyung Park, Preston Edge, Hong Li, M.S., Connie M. Piccone, MD, Jane A. Little, MD

Blood (2015) 126 (23): 3267.

https://doi.org/10.1182/blood.V126.23.3267.3267

Published: 2015

Journal Articles

Effects of Genetic Polymorphisms on Leukocyte and Neutrophil Counts and Maximum Tolerated Dose of Hydroxyurea in Children with Sickle Cell Anemia

Beverly A Schaefer, MD, Jonathan M Flanagan, PhD, Thad A. Howard, MS, Kerri A Nottage, MD MPH, Connie M. Piccone, MD, Scott T. Miller, MD, Alex George, MD, PhD, Beatrice E. Gee, MD, Barry R Davis, MDPhD, Russell E. Ware, MD PhD

Blood (2015) 126 (23): 2165.

https://doi.org/10.1182/blood.V126.23.2165.2165

Published: 2015

Journal Articles

Hydroxyurea Shows Clinical Benefit without Alteration of Fetal Hemoglobin, MCV, or Hemoglobin in Unselected Adult and Pediatric Patients with Sickle Cell Anemia

Crawford John Strunk, MD, Biree Andemariam, MD, Fredericka Sey, MB ChB, Fatimah Farooq, BS, Rebekah Urbonya, BS, Charles Antwi-Boasiako, PhD, Adetola A. Kassim, MD MS, Onike Rodrigues, MD, Connie M. Piccone, MD, Angela Rivers, MD PhD, Deepa Manwani, MD, Imma Tartaglione, MD, Laura Sainati, MD, Raffaella Colombatti, MDPhD, Andrew D. Campbell, MD

Blood (2015) 126 (23): 2187.

https://doi.org/10.1182/blood.V126.23.2187.2187

Published: 2015

Journal Articles

TCD with Transfusions Changing to Hydroxyurea (TWiTCH): Hydroxyurea Therapy As an Alternative to Transfusions for Primary Stroke Prevention in Children with Sickle Cell Anemia

Russell E. Ware, MD PhD, Barry R Davis, MD PhD, William H Schultz, MHS PA, Clark Brown, MD PhD, Banu Aygun, MD, Sharada A. Sarnaik, MD, Isaac Odame, MD, Beng Fuh, MD, Alex George, MD, PhD, William Owen, MD, Lori Luchtman-Jones, MD, Zora R. Rogers, MD, Lee Hilliard, MD, Cynthia Gauger, MD, Connie M. Piccone, MD, Margaret T. Lee, MD, Janet Kwiatkowski, MD, Sherron Jackson, MD, Scott T. Miller, MD, Carla W Roberts, MD, Matthew M. Heeney, MD FRCP(C), Theodosia A. Kalfa, MD PhD, Stephen C Nelson, MD, Hamayun Imran, MD, Kerri A Nottage, MD MPH, Ofelia A. Alvarez, MD, Melissa Rhodes, MD, Alexis A. Thompson, MD, Jennifer Rothman, MD, Kathleen J. Helton, MD, Donna Roberts, MD, Jamie Coleman, MD, Melanie J Bonner, PhD, Abdullah Kutlar, MD, Niren Patel, MD, John C Wood, MD PhD, Linda Piller, MD, Peng Wei, PhD, Judy Luden, CCRP, Nicole A. Mortier, MHS, PA-C, Susan Stuber, MA, Naomi L.C. Luban, MD, Alan R. Cohen, MD, Sara L Pressel, MS, Robert J. Adams, MD MS

Blood (2015) 126 (23): 3.

https://doi.org/10.1182/blood.V126.23.3.3

Published: 2015

Journal Articles

Identifying Renal Microstructural and Blood Flow Changes in Sickle Cell Disease Using Quantitative MRI Techniques

Connie M. Piccone, MD, Lan Lu, PhD, Shannon Donnola, Katherine Dell, MD, Jane A. Little, MD, Chris Flask, PhD

Blood (2014) 124 (21): 4074.

https://doi.org/10.1182/blood.V124.21.4074.4074

Published: 2014

Journal Articles

Sickle Cell Disease Proteinuria Is Not Associated With Systolic Blood Pressure, CSSCD-Defined Hypertension, or Family History Of Hypertension In An International Cohort Of SCD Patients

Andrew Campbell, MD, Biree Andemariam, MD, Fredericka Sey, MD, Connie M. Piccone, MD, Baba PD Inusa, MD, FRCPCH, Silverio Perrotta, MD, Imma Tartaglione, MD, William Zempsky, MD, Crawford John Strunk, MD, Rebekah Urbonya, Laura Sainati, MD, Adetola A. Kassim, MD, Charles Antwi-Boasiako, M.S., Deepa Manwani, M.D, Raffaella Colombatti, MD PhD

Blood (2013) 122 (21): 981.

https://doi.org/10.1182/blood.V122.21.981.981

Published: 2013

Journal Articles

Estimating Iron Burden in Simple Vs. Modified Manual Exchange Transfusions in Pediatric Sickle Cell Patients on Chronic Transfusions

Mansi Lalwani, MD, Mary DeBarr, RN, BSN, Ann O'Riordan Mary, Connie M Piccone, MD, Brian W Berman, MD

Blood (2011) 118 (21): 4850.

https://doi.org/10.1182/blood.V118.21.4850.4850

Published: 2011

Journal Articles

23 Years of Management: A Retrospective Review of Treatment for Aplastic Anemia.

Connie M Piccone, MD, Marie Boorman Martin, RN, Zung Vu Tran, PhD, Kim Smith-Whitley, MD

Blood (2009) 114 (22): 1091.

https://doi.org/10.1182/blood.V114.22.1091.1091

Published: 2009

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Individualized, PK-Guided Dosing of Hydroxyurea for Young Children with Sickle Cell Anemia: Final Results from the Hydroxyurea Optimization through Precision Study (HOPS)

Individualized, PK-Guided Dosing of Hydroxyurea Is Not Associated with Increased Hematologic Toxicity Compared to Weight-Based Initial Dosing: Interim Results from the Hops Trial

Addressing Recruitment Challenges in the Engage-HU Trial in Young Children with Sickle Cell Disease

An Analysis of Racial and Ethnic Backgrounds within the Casire International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research

International Multi-Site Clinical Validation of Point-of-Care Microchip Electrophoresis Test for Hemoglobin Variant Identification

Clinical Practice Patterns for Hydroxyurea Initiation in Young Children with Sickle Cell Disease

Initial Results from a Cohort in a Phase 2a Study (GBT440-007) Evaluating Adolescents with Sickle Cell Disease Treated with Multiple Doses of GBT440, a HbS Polymerization Inhibitor

Pediatric Hematologists' Clinical Practices and Perspectives of Hematopoietic Cell Transplantation As a Treatment Option for Sickle Cell Disease

History of Asthma is Associated with Albuminuria within an International Pediatric Cohort of Sickle Cell Disease Patients: A Casire Group Analysis

Parent and Guardian Knowledge of Hematopoietic Cell Transplantation As a Treatment Option for Sickle Cell Disease

Agreement Between R2 and R2* Liver Iron Estimates Is Independent of the Type of Iron Removal Therapy: Results from the Twitch Trial

Point-of-Care Screening for Sickle Cell Disease By a Mobile Micro-Electrophoresis Platform

Acute Care in the Emergency Department Differs before and after Transition for Adolescents and Young Adults with Sickle Cell Disease

Effects of Genetic Polymorphisms on Leukocyte and Neutrophil Counts and Maximum Tolerated Dose of Hydroxyurea in Children with Sickle Cell Anemia

Hydroxyurea Shows Clinical Benefit without Alteration of Fetal Hemoglobin, MCV, or Hemoglobin in Unselected Adult and Pediatric Patients with Sickle Cell Anemia

TCD with Transfusions Changing to Hydroxyurea (TWiTCH): Hydroxyurea Therapy As an Alternative to Transfusions for Primary Stroke Prevention in Children with Sickle Cell Anemia

Identifying Renal Microstructural and Blood Flow Changes in Sickle Cell Disease Using Quantitative MRI Techniques

Sickle Cell Disease Proteinuria Is Not Associated With Systolic Blood Pressure, CSSCD-Defined Hypertension, or Family History Of Hypertension In An International Cohort Of SCD Patients

Estimating Iron Burden in Simple Vs. Modified Manual Exchange Transfusions in Pediatric Sickle Cell Patients on Chronic Transfusions

23 Years of Management: A Retrospective Review of Treatment for Aplastic Anemia.

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