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Journal Articles

Uncovering a Covert Enemy: Systemic AL Amyloidosis Associated With Intravascular Diffuse Large B-Cell Lymphoma

Joseph J. Shatzel, MD, Rebecca Wang, BS, Regina C. Lee, MD, Saurabh Malhotra, MD, Kabir Mody, MD, Deborah L. Ornstein, MD, Christopher H. Lowrey, MD

Blood (2013) 122 (21): 5066.

https://doi.org/10.1182/blood.V122.21.5066.5066

Published: 2013

Journal Articles

Microrna Expression In Patients With Myelodysplastic Syndromes Treated With Demethylating Agents

Meir Preis, MD, PhD, Gregory J Tsongalis, PhD, Christopher H. Lowrey, MD, Deborah L. Ornstein, MD

Blood (2013) 122 (21): 3758.

https://doi.org/10.1182/blood.V122.21.3758.3758

Published: 2013

Journal Articles

Salubrinal Increases Human Fetal Hemoglobin Production Through a Post-Transcriptional Mechanism

Cynthia K Hahn, BA, Christopher H. Lowrey, MD

Blood (2012) 120 (21): 250.

https://doi.org/10.1182/blood.V120.21.250.250

Published: 2012

Journal Articles

p38 MAPK Signalling Is Not Sufficient to Induce γ-Globin Gene Expression

Emily K Schaeffer, BSc, Rachel J West, PhD, Cynthia K Hahn, BA, Christopher H. Lowrey, MD

Blood (2011) 118 (21): 1083.

https://doi.org/10.1182/blood.V118.21.1083.1083

Published: 2011

Journal Articles

Simvastatin and tBHQ Act Synergistically to Increase γ-Globin Gene Expression Through the Transcription Factors KLF2 and NRF2

Elizabeth R Macari, BS, Christopher H. Lowrey, MD

Blood (2011) 118 (21): 2149.

https://doi.org/10.1182/blood.V118.21.2149.2149

Published: 2011

Journal Articles

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Elizabeth R. Macari, BS, Rachel J. West, PhD, Christopher H. Lowrey, MD

Blood (2010) 116 (21): 2074.

https://doi.org/10.1182/blood.V116.21.2074.2074

Published: 2010

Journal Articles

Dual-Specificity Phosphatases (DUSPs) Are Potential Targets for Pharmacologic Induction of Fetal Hemoglobin

Cynthia K Hahn, BA, Rachel J West, PhD, Elizabeth R Macari, BS, Emily K Schaeffer, BSc, Christopher H. Lowrey, MD

Blood (2010) 116 (21): 2075.

https://doi.org/10.1182/blood.V116.21.2075.2075

Published: 2010

Journal Articles

X-Ray and UV Irradiation and Heat Shock Induce γ-Globin Gene Expression in Erythroid Cells Via P38 MAPK Signaling.

Rachel West, PhD, Rodwell Mabaera, PhD, Sarah Conine, Elizabeth Macari, BS, William J. Lowrey, Anais L Carniciu, Christopher H. Lowrey, MD

Blood (2009) 114 (22): 459.

https://doi.org/10.1182/blood.V114.22.459.459

Published: 2009

Journal Articles

Induction of γ-Globin Gene Expression Via the Nrf2/Antioxidant Response Element Signaling Pathway.

Elizabeth Macari, BS, Rachel West, PhD, William J. Lowrey, Rodwell Mabaera, PhD, Christopher H. Lowrey, MD

Blood (2009) 114 (22): 975.

https://doi.org/10.1182/blood.V114.22.975.975

Published: 2009

Journal Articles

5-Azacytidine Induces Human Fetal Hemoglobin Production through Activation of the p38 MAPK and Integrated Stress Response Signaling Pathways

Rodwell Mabaera, Christopher H. Lowrey, MD

Blood (2008) 112 (11): 489.

https://doi.org/10.1182/blood.V112.11.489.489

Published: 2008

Journal Articles

Neither DNA Hypomethylation or Changes in the Kinetics of Erythroid Differentiation Account for 5-Azacytidine’s Ability To Induce Human Fetal Hemoglobin.

Rodwell Mabaera, BA, Michael R. Greene, MD, Christine A. Richardson, MA, Sarah J. Conine, Christopher H. Lowrey, MD

Blood (2007) 110 (11): 572.

https://doi.org/10.1182/blood.V110.11.572.572

Published: 2007

Journal Articles

5-Azacytidine Induction of Human γ-Globin Gene Expression: Experimental Evaluation of Current Models.

Rodwell Mabaera, BA, Christine Richardson, MS, Sarah Conine, Christopher H. Lowrey, MD

Blood (2006) 108 (11): 1581.

https://doi.org/10.1182/blood.V108.11.1581.1581

Published: 2006

Journal Articles

Developmental and Differentiation-Specific Patterns of γ- and β-Globin Promoter DNA Methylation in Primary Human Erythroid Cells.

Christine Richardson, MS, Rodwell Mabaera, BA, Christopher H. Lowrey, MD

Blood (2006) 108 (11): 1586.

https://doi.org/10.1182/blood.V108.11.1586.1586

Published: 2006

Journal Articles

In Vivo GATA-1 Binding to an LCR Core Element Requires Flanking Krupple-Like Factor Biniding Sites Which Direct the Formation of a Chromatin Mini-Domain.

Rachel West, PhD, Mitchell Ermentrout, BA, Catherine Ackley, PhD, Christopher H. Lowrey, MD

Blood (2006) 108 (11): 364.

https://doi.org/10.1182/blood.V108.11.364.364

Published: 2006

Journal Articles

Specificity Protein 1 (Sp1) Consensus Binding Sequences Flank Many Functional GATA-1 Binding Sites and Are Sufficient To Allow GATA-1 Binding to a WGATAR Sequence in Nuclear Chromatin.

Priya Venkatesan, PhD, Christopher H. Lowrey, MD

Blood (2006) 108 (11): 363.

https://doi.org/10.1182/blood.V108.11.363.363

Published: 2006

Journal Articles

Successful PBSC Mobilization, Collection, Transplantation and Engraftment after Radioimmunotherapy with Yttrium-90 Ibritumomab Tiuxetan for Non-Hodgkin’s Lymphoma (NHL).

Pamela Ely, MD, PhD, Diane M. Stearns, ARNP, Bassem I. Zaki, MD, Thomas F. Fitzmaurice, Ph.D, Marc Gautier, MD, Christopher H. Lowrey, MD, Elizabeth M. Bengtson, MD, John M. Hill, MD, Anna D. Schaal, ARNP, Elizabeth A. Kimtis, ARNP, Lynn Root, RN, Susan Webber, MT (ASCP), BB, Zbigniew M. Szczepiorkowski, MD, Ph.D, Kenneth R. Meehan, MD

Blood (2005) 106 (11): 5517.

https://doi.org/10.1182/blood.V106.11.5517.5517

Published: 2005

Journal Articles

The Binding of GATA-1 to a β-Globin LCR HS Core Element in Nuclear Chromatin Requires Multiple Associated Factor Binding Sites.

Christopher H. Lowrey, MD, Catherine Ackley, PhD, Mitchell Ermentrout, BA

Blood (2005) 106 (11): 528.

https://doi.org/10.1182/blood.V106.11.528.528

Published: 2005

Journal Articles

A Comparison of Five Different Culture Protocols Shows That Growth of Human CD34+ Peripheral Blood Stem Cells in SCF, IL-3, Flt-3 Ligand and EPO Results in Exponential Erythroid Expansion and a Globin Gene Expression Pattern Which Is Similar to That Seen in Human Bone Marrow.

Rodwell H. Mabaera, BA, Christopher H. Lowrey, MD

Blood (2005) 106 (11): 3649.

https://doi.org/10.1182/blood.V106.11.3649.3649

Published: 2005

Journal Articles

The Effects of Lead and Cadmium on Erythroid Differentiation and Gata-1 Regulated Gene Expression.

R. Mitchell R. Ermentrout, Michael E. Layon, PhD, Catherine J. Ackley, Christopher H. Lowrey, MD

Blood (2004) 104 (11): 3705.

https://doi.org/10.1182/blood.V104.11.3705.3705

Published: 2004

Journal Articles

The Human Xist Gene Promoter Prevents Silencing of an Integrated Reporter Gene.

Michael R. Greene, MD, Christopher H. Lowrey, MD

Blood (2004) 104 (11): 2114.

https://doi.org/10.1182/blood.V104.11.2114.2114

Published: 2004

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Uncovering a Covert Enemy: Systemic AL Amyloidosis Associated With Intravascular Diffuse Large B-Cell Lymphoma

Microrna Expression In Patients With Myelodysplastic Syndromes Treated With Demethylating Agents

Salubrinal Increases Human Fetal Hemoglobin Production Through a Post-Transcriptional Mechanism

p38 MAPK Signalling Is Not Sufficient to Induce γ-Globin Gene Expression

Simvastatin and tBHQ Act Synergistically to Increase γ-Globin Gene Expression Through the Transcription Factors KLF2 and NRF2

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Dual-Specificity Phosphatases (DUSPs) Are Potential Targets for Pharmacologic Induction of Fetal Hemoglobin

X-Ray and UV Irradiation and Heat Shock Induce γ-Globin Gene Expression in Erythroid Cells Via P38 MAPK Signaling.

Induction of γ-Globin Gene Expression Via the Nrf2/Antioxidant Response Element Signaling Pathway.

5-Azacytidine Induces Human Fetal Hemoglobin Production through Activation of the p38 MAPK and Integrated Stress Response Signaling Pathways

Neither DNA Hypomethylation or Changes in the Kinetics of Erythroid Differentiation Account for 5-Azacytidine’s Ability To Induce Human Fetal Hemoglobin.

5-Azacytidine Induction of Human γ-Globin Gene Expression: Experimental Evaluation of Current Models.

Developmental and Differentiation-Specific Patterns of γ- and β-Globin Promoter DNA Methylation in Primary Human Erythroid Cells.

In Vivo GATA-1 Binding to an LCR Core Element Requires Flanking Krupple-Like Factor Biniding Sites Which Direct the Formation of a Chromatin Mini-Domain.

Specificity Protein 1 (Sp1) Consensus Binding Sequences Flank Many Functional GATA-1 Binding Sites and Are Sufficient To Allow GATA-1 Binding to a WGATAR Sequence in Nuclear Chromatin.

Successful PBSC Mobilization, Collection, Transplantation and Engraftment after Radioimmunotherapy with Yttrium-90 Ibritumomab Tiuxetan for Non-Hodgkin’s Lymphoma (NHL).

The Binding of GATA-1 to a β-Globin LCR HS Core Element in Nuclear Chromatin Requires Multiple Associated Factor Binding Sites.

A Comparison of Five Different Culture Protocols Shows That Growth of Human CD34+ Peripheral Blood Stem Cells in SCF, IL-3, Flt-3 Ligand and EPO Results in Exponential Erythroid Expansion and a Globin Gene Expression Pattern Which Is Similar to That Seen in Human Bone Marrow.

The Effects of Lead and Cadmium on Erythroid Differentiation and Gata-1 Regulated Gene Expression.

The Human Xist Gene Promoter Prevents Silencing of an Integrated Reporter Gene.

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