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Christopher Bebbington, DPhil
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Journal Articles

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

Eric Padron, MD, Jeffrey S Painter, BS, Adam W Mailloux, PhD, Kathy L. McGraw, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Geoffrey Yarranton, PhD, Jeffrey E Lancet, MD, Rami S. Komrokji, MD, Alan F. List, MD, P.K. Epling-Burnette, PharmD, PhD
Journal: Blood
Blood (2012) 120 (21): 3793.
https://doi.org/10.1182/blood.V120.21.3793.3793
Published: 2012
Journal Articles

A Recombinant Antibody to EphA3 for the Treatment of Hematologic Malignancies: Research Update and Interim Phase 1 Study Results

Anne Hagey, M.D., Jeffrey E. Lancet, MD, Varghese Palath, PhD, Andrew H Wei, MBBS, PhD, Martin Lackmann, PhD, Jorge E. Cortes, Andrew Boyd, MD, PhD, Dan Shochat, PhD, Geoffrey Yarranton, PhD, Christopher Bebbington, DPhil., Jonathan A. Leff, MD
Journal: Blood
Blood (2011) 118 (21): 4893.
https://doi.org/10.1182/blood.V118.21.4893.4893
Published: 2011
Journal Articles

GM-CSF Signaling Abnormalities in Chronic Myelomonocytic Leukemia

Eric Padron, MD, Jeffrey S. Painter, B.S., Adam W Mailloux, PhD, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Rami S. Komrokji, MD, Alan F. List, MD, Pearlie K Epling-Burnette, Pharm D, PhD
Journal: Blood
Blood (2011) 118 (21): 1713.
https://doi.org/10.1182/blood.V118.21.1713.1713
Published: 2011
Journal Articles

A Recombinant Antibody to EphA3 with Pro-Apoptotic and Enhanced ADCC Activity Against Various Hematologic Malignancies Shows Selective Inhibition of Colony Formation From Long-Term Culture-Initiating Cells (LTC-ICs) In Primary Leukemia Samples

Varghese Palath, PhD, Rohini Vekhande, Mark Baer, PhD, Wendy Ching, PhD, Nenad Tomasevic, PhD, David Martinez, Christina Yi, Swathi Bhaskar, Kenneth Luehrsen, Jason Williams, John Leung, Alan F. List, MD, Ling Zhang, MD, Martin Lackmann, PhD, Andrew Boyd, MD, PhD, Andrew Scott, PhD, Daniela Cilloni, MD, PhD, Geoffrey Yarranton, PhD, Christopher Bebbington, DPhil.
Journal: Blood
Blood (2010) 116 (21): 2897.
https://doi.org/10.1182/blood.V116.21.2897.2897
Published: 2010
Journal Articles

A Recombinant Human Antibody to EphA3 with Pro-Apoptotic and Enhanced ADCC Activity Shows Selective Cytotoxicity against Myeloid Leukemia Cells and CD123-Positive Leukemic Stem Cells.

Varghese Palath, PhD, Rohini Vekhande, Andreia Lee, Jason Williams, Ling Zhang, MD, Alan F List, MD, Andrew Boyd, MD, PhD, Martin Lackmann, PhD, Andrew M Scott, PhD, Daniela Cilloni, MD, PhD, Geoffrey T. Yarranton, PhD, Christopher Bebbington, DPhil
Journal: Blood
Blood (2009) 114 (22): 1728.
https://doi.org/10.1182/blood.V114.22.1728.1728
Published: 2009