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Journal Articles

Machine Learning Unveils Proteotypic Mimicry in Genetically Defined SCN Variants

Sebastian Hesse, MD, Christoph Klein, MD PhD, Rappsilber Juri, Prof., Yoko Mizoguchi, Monika Linder, PhD, Piotr Grabowski, PhD, Zahra Alizadeh, PhD, Zahra Pourpak, MD PhD, Nima Rezaei, MD PhD, Sorin Iurian, MD PhD, Ekrem Unal, MD, Fabian Hauck, MD PhD, Ralf Zimmer, Prof., Gergely Csaba, PhD

Blood (2019) 134 (Supplement_1): 3580.

https://doi.org/10.1182/blood-2019-131136

Published: 2019

Journal Articles

Novel Immune Checkpoint Deficiency and Susceptibility to EBV-Associated Lymphoma

Ido Somekh, Thomas Magg, PhD, Alejandro Gallón Duque, Tali Stauber, MD, Atar Lev, MSc, Ekrem Unal, MD, Amos J. Simon, PhD, Meino Rohlfs, PhD, Raffaele Conca, MSc, Megumi Tatematsu, PhD, Fabian Hauck, MD PhD, Raz Somech, MD PhD, Christoph Klein, MD PhD

Blood (2019) 134 (Supplement_1): 2326.

https://doi.org/10.1182/blood-2019-128296

Published: 2019

Journal Articles

Defects in Signal Recognition Particle (SRP) Components Reveal an Essential and Non-Redundant Role for Granule Biogenesis and Differentiation of Neutrophil Granulocytes

Blood (2019) 134 (Supplement_1): 216.

https://doi.org/10.1182/blood-2019-130083

Published: 2019

Journal Articles

Bone Marrow T Cells Are Driven into Exhaustion By Acute Leukemia in Pediatric Patients Based on Protein and Transcriptome Analysis

Semjon Willier, MD, Paula Rothaemel, Jonas Wilhelm, Dana Stenger, Theresa Kaeuferle, PhD, Irene Schmid, MD, Michael H. Albert, MD, Vera Binder, MD, Meino Rohlfs, PhD, Sebastian Hollizeck, Christoph Klein, MD PhD, Franziska Blaeschke, MD, Tobias Feuchtinger, MD

Blood (2018) 132 (Supplement 1): 3722.

https://doi.org/10.1182/blood-2018-99-112811

Published: 2018

Journal Articles

LAMTOR2 Is Dispensable for T Cell Receptor-Mediated Signaling of Thymocytes but Controls Medullary Thymic Epithelial Cells

Lina Wendeler, MSc, Lukas A Huber, MD, Christoph Klein, MD PhD, Daniel Kotlarz, MD PhD

Blood (2018) 132 (Supplement 1): 1122.

https://doi.org/10.1182/blood-2018-99-119645

Published: 2018

Journal Articles

Busulfan/Fludarabine- or Treosulfan/Fludarabine-Based Conditioning Regimen in Patients with Wiskott-Aldrich Syndrome Given Allogeneic Hematopoietic Cell Transplantation — an EBMT Inborn Errors Working Party and Scetide Retrospective Analysis

Blood (2018) 132 (Supplement 1): 2175.

https://doi.org/10.1182/blood-2018-99-112394

Published: 2018

Journal Articles

TIM-3 Expression on CD4 + Bone Marrow T Cells Predicts Relapse of Pediatric B-Precursor Acute Lymphoblastic Leukemia

Franziska Blaeschke, MD, Semjon Willier, MD, Dana Stenger, Mareike Lepenies, Martin A. Horstmann, MD, Gabriele Escherich, Martin Zimmermann, PhD, Theresa Kaeuferle, PhD, Meino Rohlfs, PhD, Irene Schmid, MD, Michael H. Albert, MD, Vera Binder, MD, Christoph Klein, MD PhD, Tobias Feuchtinger, MD

Blood (2018) 132 (Supplement 1): 2833.

https://doi.org/10.1182/blood-2018-99-118376

Published: 2018

Journal Articles

Next Generation Proteomics of Human Neutrophil Granulocytes in Monogenic Disease

Sebastian Hesse, MD, Christoph Klein, MD PhD, Piotr Grabowski, Rappsilber Juri, Prof., Uta Behrends, Prof. Dr., Roya Sherkat, Prof., Ekrem Unal, MD

Blood (2018) 132 (Supplement 1): 15.

https://doi.org/10.1182/blood-2018-99-114764

Published: 2018

Journal Articles

Response to Front-Line Imatinib Treatment in Children and Adolescents with CML - Data from a Large Pediatric Cohort

Blood (2017) 130 (Supplement 1): 898.

https://doi.org/10.1182/blood.V130.Suppl_1.898.898

Published: 2017

Journal Articles

Novel Mutations in RASGRP1 Are Associated with Immune Dysregulation and Predispose to EBV-Induced Lymphoma

Ido Somekh, MD, Benjamin Marquardt, MSc, Yanshan Liu, PhD, Meino Rohlfs, PhD, Shirly Frizinsky, MD, Ekrem Unal, MD, Daniel Kotlarz, MD PhD, Raz Somech, MD PhD, Christoph Klein, MD PhD

Blood (2017) 130 (Supplement 1): 2287.

https://doi.org/10.1182/blood.V130.Suppl_1.2287.2287

Published: 2017

Journal Articles

Rltpr Is a Central Scaffold Protein Regulating Human TCR Co-Signaling and Cytoskeletal Dynamics

Tilmann Schober, MD, Thomas Magg, PhD, Melanie Laschinger, PhD, Thomas Fröhlich, PhD, Meino Rohlfs, PhD, Yanshan Liu, PhD, Jacek Puchalka, PhD, Tanja Weisser, Karin Fehlner, PhD, Christoph Walz, MD, Natália Duarte Linhares, PhD, Sérgio D. Pena, MD PhD, Bernd H. Belohradsky, MD, Christoph Klein, MD PhD, Fabian Hauck, MD PhD

Blood (2016) 128 (22): 131.

https://doi.org/10.1182/blood.V128.22.131.131

Published: 2016

Journal Articles

Wiskott-Aldrich Syndrome: A Retrospective Study on 575 Patients Analyzing the Impact of Splenectomy, Stem Cell Transplantation, or No Definitive Treatment on Frequency of Disease-Related Complications and Physician-Perceived Quality of Life

Jannik S Glasmacher, Tanja C Bittner, MD, Hans D Ochs, MD, Alessandro Aiuti, MD PhD, Peter D Arkwright, MD, Dmitry Balashov, Uta Behrends, Bernd H. Belohradsky, MD, Elisa Bertoni, David K. Buchbinder, MD MSHS, Michael Browning, Anastasiia Bondarenko, Fabio Candotti, MD, Alessandro Cattoni, Liudmyla Chernyshova, Joseph H. Chewning, MD, Peter Ciznar, Theresa Cole, Beatriz T Costa-Carvalho, Wojciech Czogala, Gregor Dueckers, David M Edgar, Fatih Erbey, Anders Fasth, MD PhD, Renata Formankova, MD PhD, Tomas Freiberger, Eleonora Gambineri, Andrew Gennery, MD, Frederick D Goldman, MD, Luis I Gonzalez-Granado, Tiago N Gulmaraes, David Hagin, MD PhD, Fabian Hauck, MD PhD, Tarja Heiskanen-Kosma, Manfred Hoenig, MD, Hanna Juntti, Hirokazu Kanegane, Leena Kainulainen, Neslihan E Karaca, Sara S Kilic, Christoph Klein, MD PhD, Sylwia Koltan, Irina Kondratenko, Dawei Liu, MD, Susanne Matthes, MD, Juliana T L Mazzucchelli, Isabelle Meyts, Siraj Misbah, Zohreh Nademi, Gulnara Nasrullayeva, Lucia D Notarangelo, Pere Soler-Palacin, Olga Pashchenko, Srdjan Pasic, Isabelle Pellier, MD, Claudio Pignata, Camilla Roepstorff, Catharina Schuetz, Ansgar S Schulz, MD PhD Prof., Gesmar R S Segundo, Anna Shcherbina, Joanne Smart, Robert A. Sokolic, MD, Polina Stepensky, MD, Troy Torgerson, MD PhD, Svetlana Vakhlyarskaya, Joris van Montfrans, MD PhD, Kim Vettenranta, MD PD, Beata Wolska-Kusnierz, Xiaodong Zhao, John B Ziegler, Xuan Zhang, Michael H. Albert, MD

Blood (2016) 128 (22): 366.

https://doi.org/10.1182/blood.V128.22.366.366

Published: 2016

Journal Articles

SWI/SNF Protein SMARCD2 Orchestrates Transcriptional Networks Controlling Hematopoiesis and Neutrophil Granulocytes in Humans, Mice and Zebrafish

Blood (2016) 128 (22): 2.

https://doi.org/10.1182/blood.V128.22.2.2

Published: 2016

Journal Articles

A Human Bone Marrow Failure Syndrome Caused By a Homozygous Mutation in MYSM1

Ehsan Bahrami, Tomas Racek, PhD, Maximilian Witzel, MD, Jacek Puchalka, PhD, Naschla Greif-Kohistani, MD, Daniel Kotlarz, MD PhD, Michael Orth, PhD, Kirsten Lauber, PhD, Christoph Walz, MD, Waleed Al Herz, MD, Hans-Peter Horny, MD, Heinrich Schmidt, MD, Michael H. Albert, MD, Christoph Klein, MD PhD

Blood (2015) 126 (23): 1204.

https://doi.org/10.1182/blood.V126.23.1204.1204

Published: 2015

Journal Articles

Complete Block of Early B Cell Differentiation in Mice Lacking the Endosomal Adaptor Protein p14

Marcin Lyszkiewicz, PhD, Daniel Kotlarz, MD PhD, Natalia Zietara, PhD, Gudrun Brandes, PhD, Jana Diestelhorst, Silke Glage, DVM, Eliash Hobeika, PhD, Michael Reth, Prof., PhD, Lukas Huber, MD Prof., Andreas Krueger, PhD Prof., Christoph Klein, MD PhD

Blood (2015) 126 (23): 1026.

https://doi.org/10.1182/blood.V126.23.1026.1026

Published: 2015

Journal Articles

Response-Adapted Sequential Immuno-Chemotherapy of Post-Transplant Lymphoproliferative Disorders in Pediatric Solid Organ Transplant Recipients: Results from the Prospective Ped-PTLD 2005 Trial

Britta Maecker-Kolhoff, MD, Rita Beier, MD, Martin Zimmermann, PhD, Brigitte Schlegelberger, MD, Ulrich Baumann, MD, Carsten Mueller, MD, Lars Pape, MD, Alfred Reiter, MD, Claudia Rossig, MD, Stephan Schubert, MD, Burkhard Toenshoff, MD, Anne-Margret Wingen, MD, Barbara Meissner, MD, Christian Kebelmann-Betzing, MD, Guenter Henze, MD, Hans H. Kreipe, MD, Christoph Klein, MD PhD

Blood (2014) 124 (21): 4468.

https://doi.org/10.1182/blood.V124.21.4468.4468

Published: 2014

Journal Articles

A Rare Case of Congenital Atransferrinemia: International Collaboration for Genetic Diagnosis

Hanan Nazir, MD, Murtadha K. Al-Khabori, MD MSc, FRCPC, Naschla Kohistani, MD, Jacek Puchalka, PhD, Christoph Klein, MD PhD

Blood (2014) 124 (21): 4883.

https://doi.org/10.1182/blood.V124.21.4883.4883

Published: 2014

Journal Articles

LAMTOR2 Regulates Stem Cell Maintenance and Acts in Lineage Choice By Modulating Cytokine Receptor-Mediated Signaling

Daniel Kotlarz, MD, Gudrun Brandes, PhD, Schwarzer Adrian, MD PhD, Glage Silke, MD, Büsche Guntram, MD, Pfeifer Dietmar, PhD, Lukas A Huber, MD, Christoph Klein, MD PhD

Blood (2014) 124 (21): 249.

https://doi.org/10.1182/blood.V124.21.249.249

Published: 2014

Journal Articles

Haploidentical Transplantation with Post-Transplant Cyclophosphamide in Children with Malignant and Non-Malignant Diseases

Michael H. Albert, MD, Johanna Tischer, MD, Daniel Stachel, MD, Anna von Schirnding de Almeida, MD, Volker Wiebking, MD, Christoph Klein, MD PhD, Irene Schmid, MD

Blood (2014) 124 (21): 5842.

https://doi.org/10.1182/blood.V124.21.5842.5842

Published: 2014

Journal Articles

Hodgkin’s Disease / Hodgkin-PTLD after Solid Organ Transplantation in Children: A Report on 16 Patients Treated According to Subsequent Gpoh-HD Treatment Schedules

Johanna Kampers, Rita Beier, MD, Manuela A. Orjuela-Grimm, MD ScM, Tilmann Schober, MD, Thomas Schulz, MD, Martina Stiefel, MD, Christoph Klein, MD PhD, Christine Mauz-Koerholz, MD, Hans H. Kreipe, MD, Britta Maecker-Kolhoff, MD

Blood (2014) 124 (21): 1612.

https://doi.org/10.1182/blood.V124.21.1612.1612

Published: 2014

NARROW

Machine Learning Unveils Proteotypic Mimicry in Genetically Defined SCN Variants

Novel Immune Checkpoint Deficiency and Susceptibility to EBV-Associated Lymphoma

Defects in Signal Recognition Particle (SRP) Components Reveal an Essential and Non-Redundant Role for Granule Biogenesis and Differentiation of Neutrophil Granulocytes

Bone Marrow T Cells Are Driven into Exhaustion By Acute Leukemia in Pediatric Patients Based on Protein and Transcriptome Analysis

LAMTOR2 Is Dispensable for T Cell Receptor-Mediated Signaling of Thymocytes but Controls Medullary Thymic Epithelial Cells

Busulfan/Fludarabine- or Treosulfan/Fludarabine-Based Conditioning Regimen in Patients with Wiskott-Aldrich Syndrome Given Allogeneic Hematopoietic Cell Transplantation — an EBMT Inborn Errors Working Party and Scetide Retrospective Analysis

TIM-3 Expression on CD4 + Bone Marrow T Cells Predicts Relapse of Pediatric B-Precursor Acute Lymphoblastic Leukemia

Next Generation Proteomics of Human Neutrophil Granulocytes in Monogenic Disease

Response to Front-Line Imatinib Treatment in Children and Adolescents with CML - Data from a Large Pediatric Cohort

Novel Mutations in RASGRP1 Are Associated with Immune Dysregulation and Predispose to EBV-Induced Lymphoma

Rltpr Is a Central Scaffold Protein Regulating Human TCR Co-Signaling and Cytoskeletal Dynamics

Wiskott-Aldrich Syndrome: A Retrospective Study on 575 Patients Analyzing the Impact of Splenectomy, Stem Cell Transplantation, or No Definitive Treatment on Frequency of Disease-Related Complications and Physician-Perceived Quality of Life

SWI/SNF Protein SMARCD2 Orchestrates Transcriptional Networks Controlling Hematopoiesis and Neutrophil Granulocytes in Humans, Mice and Zebrafish

A Human Bone Marrow Failure Syndrome Caused By a Homozygous Mutation in MYSM1

Complete Block of Early B Cell Differentiation in Mice Lacking the Endosomal Adaptor Protein p14

Response-Adapted Sequential Immuno-Chemotherapy of Post-Transplant Lymphoproliferative Disorders in Pediatric Solid Organ Transplant Recipients: Results from the Prospective Ped-PTLD 2005 Trial

A Rare Case of Congenital Atransferrinemia: International Collaboration for Genetic Diagnosis

LAMTOR2 Regulates Stem Cell Maintenance and Acts in Lineage Choice By Modulating Cytokine Receptor-Mediated Signaling

Haploidentical Transplantation with Post-Transplant Cyclophosphamide in Children with Malignant and Non-Malignant Diseases

Hodgkin’s Disease / Hodgkin-PTLD after Solid Organ Transplantation in Children: A Report on 16 Patients Treated According to Subsequent Gpoh-HD Treatment Schedules

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American Society of Hematology

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American Society of Hematology

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