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Journal Articles

Synthetic Lethal Interaction between Apto-253 and IDH1/2 Mutations

Cheng-Yu Tsai, PhD, Hongying Zhang, MD PhD, William G Rice, PhD, Stephen B Howell, MD

Blood (2019) 134 (Supplement_1): 5755.

https://doi.org/10.1182/blood-2019-123571

Published: 2019

Journal Articles

Synthetic Lethal Interaction between Apto-253 and Impaired BRCA1/2 Function

Cheng-Yu Tsai, PhD, Si Sun, MD, Hongying Zhang, MD, Andrea Local, PhD, Khalid Benbatoul, BS, Peter Folger, BS, Susan Sheng, PhD, William Rice, PhD, Stephen Howell, MD

Blood (2017) 130 (Supplement 1): 5000.

https://doi.org/10.1182/blood.V130.Suppl_1.5000.5000

Published: 2017

Journal Articles

APTO-253 Interaction with G-Quadruplex DNA Is Linked to Inhibition of c-Myc Expression, Induction of DNA Damage, and Generation of Synthetic Lethality in Cells with BRCA1/2 Impairment

Andrea Local, PhD, Hongying Zhang, MD, Khalid Benbatoul, BS, Peter Folger, BS, Susan Sheng, PhD, Cheng-Yu Tsai, PhD, Stephen Howell, MD, William Rice, PhD

Blood (2017) 130 (Supplement 1): 5094.

https://doi.org/10.1182/blood.V130.Suppl_1.5094.5094

Published: 2017

Journal Articles

CG '806, a Highly Potent First-in-Class Pan-FLT3/BTK Inhibitor, Targets Multiple Clusters of Kinases Operative in Diverse Subtypes of Acute Myeloid Leukemia

Hongying Zhang, MD, Andrea Local, PhD, Khalid Benbatoul, BS, Peter Folger, BS, Susan Sheng, PhD, Cheng-Yu Tsai, PhD, Stephen Howell, MD, William Rice, PhD

Blood (2017) 130 (Supplement 1): 5063.

https://doi.org/10.1182/blood.V130.Suppl_1.5063.5063

Published: 2017

Journal Articles

CG '806, a First-in-Class Non-Covalent Pan-FLT3/BTK Inhibitor, Exerts Superior Potency Against B-Cell Malignant Cells

Hongying Zhang, MD, Andrea Local, PhD, Khalid Benbatoul, BS, Peter Folger, BS, Susan Sheng, PhD, Cheng-Yu Tsai, PhD, Stephen Howell, MD, William Rice, PhD

Blood (2017) 130 (Supplement 1): 5200.

https://doi.org/10.1182/blood.V130.Suppl_1.5200.5200

Published: 2017

Journal Articles

Mechanisms of Resistance to Apto-253

Cheng-Yu Tsai, PhD, Hongying Zhang, MD PhD, Andrea Local, PhD, William G. Rice, PhD, Stephen B Howell, MD

Blood (2016) 128 (22): 5247.

https://doi.org/10.1182/blood.V128.22.5247.5247

Published: 2016

NARROW

Synthetic Lethal Interaction between Apto-253 and IDH1/2 Mutations

Synthetic Lethal Interaction between Apto-253 and Impaired BRCA1/2 Function

APTO-253 Interaction with G-Quadruplex DNA Is Linked to Inhibition of c-Myc Expression, Induction of DNA Damage, and Generation of Synthetic Lethality in Cells with BRCA1/2 Impairment

CG '806, a Highly Potent First-in-Class Pan-FLT3/BTK Inhibitor, Targets Multiple Clusters of Kinases Operative in Diverse Subtypes of Acute Myeloid Leukemia

CG '806, a First-in-Class Non-Covalent Pan-FLT3/BTK Inhibitor, Exerts Superior Potency Against B-Cell Malignant Cells

Mechanisms of Resistance to Apto-253

Email alerts

ASH Publications

American Society of Hematology

Synthetic Lethal Interaction between Apto-253 and IDH1/2 Mutations

Synthetic Lethal Interaction between Apto-253 and Impaired BRCA1/2 Function

APTO-253 Interaction with G-Quadruplex DNA Is Linked to Inhibition of c-Myc Expression, Induction of DNA Damage, and Generation of Synthetic Lethality in Cells with BRCA1/2 Impairment

CG '806, a Highly Potent First-in-Class Pan-FLT3/BTK Inhibitor, Targets Multiple Clusters of Kinases Operative in Diverse Subtypes of Acute Myeloid Leukemia

CG '806, a First-in-Class Non-Covalent Pan-FLT3/BTK Inhibitor, Exerts Superior Potency Against B-Cell Malignant Cells

Mechanisms of Resistance to Apto-253

Email alerts

ASH Publications

American Society of Hematology

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