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Journal Articles

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

Karin Gustafsson, PhD, Nikolas Barkas, PhD, Ninib Baryawno, PhD, Elizabeth W Scadden, Nicolas Severe, PhD, Joel A Spencer, PhD, Hayalneh Gessessew, Kameron Kooshesh, Jimin Guo, PhD, Charles Lin, PhD, Peter Kharchenko, PhD, David T. Scadden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 586.
https://doi.org/10.1182/blood-2019-126708
Published: 2019
Journal Articles

Epigenetic Activation of the pH Regulator MCT4 in Acute Myeloid Leukemia Exploits a Fundamental Metabolic Process of Enhancing Cell Growth through Proton Shifting

Cheuk-Him Man, David T. Scadden, MD, Francois Mercier, MD FRCPC, Nian Liu, Wentao Dong, Gregory Stephanopoulos, PhD, Li Jiang, PhD, Yookyung Jung, PhD, Charles Lin, PhD, Anskar Y.-H. Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3765.
https://doi.org/10.1182/blood-2019-123604
Published: 2019
Journal Articles

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Shin-Young Park, PhD, Alessandro Mattè, BSc,PhD, Yookyung Jung, PhD, Jina Ryu, PhD, Wilson Anand, Eun Young Anna Han, B.S., Min Liu, M.S., Carmine Carbone, Davide Melisi, Takashi Nagasawa, Charles Lin, PhD, Leslie E. Silberstein, MD, Lucia De Franceschi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2256.
https://doi.org/10.1182/blood-2019-123532
Published: 2019
Journal Articles

Specific and Targetable Interactions with the Bone Marrow Microenvironment Govern Outcome in Imatinib-Resistant Chronic Myeloid Leukemia

Rahul Kumar, PhD, Maximilian Marten, Bachelors, Valentina Minciacchi, PhD, Raquel Pereira, M.Sc, Costanza Zanetti, MSc, Nina Hyduk, M.Sc, Thomas Oellerich, MD, Hans Michael Kvasnicka, MD, Joel Spencer, PhD, Frank Schnuetgen, PhD, Charles Lin, PhD, Cristina Lo Celso, PhD, Melanie Meister, PhD, Franck Emmanuel Nicolini, MD PhD, Daniela S. Krause, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 936.
https://doi.org/10.1182/blood-2018-99-111827
Published: 2018
Journal Articles

The Microanatomy of the Leukemic Stem Cell Niche in Murine Chronic Myelogenous Leukemia

Melanie Meister, Joel A Spencer, PhD, Juwell Wu, Cher Zhao, Lymperi Stefania, PhD, Francesca Ferraro, MD, Cristina Lo Celso, PhD, David T. Scadden, MD, Richard A. Van Etten, MDPhD, Charles Lin, PhD, Daniela S. Krause, MD
Journal: Blood
Blood (2014) 124 (21): 351.
https://doi.org/10.1182/blood.V124.21.351.351
Published: 2014
Journal Articles

Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors

Lev Silberstein, MDPhD, Peter Kharchenko, PhD, Youmna Kfoury, PhD, Francois Mercier, MD, Masatake Osawa, PhD, Jonathan Hoggatt, PhD, Tiffany Tate, Charles Lin, PhD, David T. Scadden, MD
Journal: Blood
Blood (2014) 124 (21): 773.
https://doi.org/10.1182/blood.V124.21.773.773
Published: 2014
Journal Articles

Real-Time RT-PCR Analysis of Individual Osteolineage Cells within the Hematopoietic Stem Cell Niche

Lev Silberstein, MD PhD, Masatake Osawa, PhD, Charles Lin, PhD, Peter Kharchenko, PhD, Cristina Lo Celso, PhD, Chiaka Aribeana, David T. Scadden, MD
Journal: Blood
Blood (2011) 118 (21): 2389.
https://doi.org/10.1182/blood.V118.21.2389.2389
Published: 2011
Journal Articles

Role of TORC1 and TORC2 in Multiple Myeloma

Patricia Maiso, PhD, Yi Liu, PhD, Abdel Kareem Azab, PhD, BSPharm, Brittany Morgan, Feda Azab, BPharm, Antonio Sacco, BS, Michaela Reagan, PhD, Hai T Ngo, BS, Yang Liu, PhD, Yong Zhang, PhD, Charles Lin, PhD, Aldo M Roccaro, MD, PhD, Christian Rommel, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2011) 118 (21): 1815.
https://doi.org/10.1182/blood.V118.21.1815.1815
Published: 2011
Journal Articles

Hypoxia Promotes Dissemination of Multiple Myeloma Through Acquisition of Endothelial to Mesenchymal Transition (EMT) Features

Abdel Kareem Azab, PhD, BSPharm, Jinsong Hu, Phong Quang, BS, Feda Azab, BPharm, Costas Pitsillides, Brian Thompson, Patricia Maiso, PhD, Aldo M Roccaro, MD, PhD, Antonio Sacco, BS, Hai T Ngo, BS, Ghayas C. Issa, MD, Charles Lin, PhD, Andrew L. Kung, MD, PhD, Karin Vanderkerken, Irene M. Ghobrial, MD
Journal: Blood
Blood (2011) 118 (21): 471.
https://doi.org/10.1182/blood.V118.21.471.471
Published: 2011
Journal Articles

The PI3K/Akt Pathway Is an Important Regulator of Homing and Adhesion in Waldenstrom’s Macroglobulinemia.

Xavier Leleu, MD, Hai Ngo, Judy Runnels, PhD, Costas Pitsillides, Joel Spencer, Anne-Sophie Moreau, MD, Evdoxia Hatjiharisi, MD, Xiaoying Jia, Garrett O’Sullivan, Steven Treon, MD, Teru Hideshima, MD, Charles Lin, PhD, Kenneth Anderson, MD, Irene Ghobrial, MD
Journal: Blood
Blood (2006) 108 (11): 2417.
https://doi.org/10.1182/blood.V108.11.2417.2417
Published: 2006