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Changshan Wang, PhD
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Journal Articles

Molecular Mechanism behind the Synergistic Activity of Proteasome Inhibition and PRC2 Inhibition in the Treatment of Multiple Myeloma

Ola Rizq, MD, Naoya Mimura, MD PhD, Motohiko Oshima, PhD, Atsunori Saraya, Shuhei Koide, PhD, Yuko Kato, PhD, Kazumasa Aoyama, PhD, Yaeko Nakajima-Takagi, PhD, Changshan Wang, PhD, Anqi Ma, Jian Jin, PhD, Tohru Iseki, MD PhD, Chiaki Nakaseko, MD, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2016) 128 (22): 312.
https://doi.org/10.1182/blood.V128.22.312.312
Published: 2016
Journal Articles

Combinatorial Epigenetic Aberration Propagates in Myelodysplastic Syndrome in the Setting of Concurrent Loss of Tet2 and Ezh2

Nagisa Hasegawa, MD, Goro Sashida, MD PhD, Motohiko Oshima, PhD, Hirotaka Matsui, MD PhD, Atsunori Saraya, Changshan Wang, PhD, Tomoya Muto, MD PhD, Chiaki Nakaseko, MD PhD, Koutaro Yokote, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2015) 126 (23): 712.
https://doi.org/10.1182/blood.V126.23.712.712
Published: 2015
Journal Articles

Epigenetic Regulation of Hematopoietic Stem and Progenitor Cells By the Eset Histone Methyltranferas

Shuhei Koide, Keiyo Takubo, MD PhD, Motohiko Oshima, PhD, Satoru Miyagi, PhD, Hirotaka Matsui, MD PhD, Hiroshi Kimura, PhD, Changshan Wang, PhD, George R Wendt, Shogo Yabata, Yoichi Shinkai, MD PhD, Toshio Suda, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2014) 124 (21): 765.
https://doi.org/10.1182/blood.V124.21.765.765
Published: 2014
Journal Articles

The Biological Function of DNA Hypermethylation in Murine MDS Model Lacking Tet2 and Ezh2

Nagisa Hasegawa, MD, Goro Sashida, MD PhD, Motohiko Oshima, PhD, Hirotaka Matsui, MD PhD, Changshan Wang, PhD, Tomoya Muto, MD PhD, Chiaki Nakaseko, MD PhD, Kotaro Yokote, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4596.
https://doi.org/10.1182/blood.V124.21.4596.4596
Published: 2014
Journal Articles

Ezh2 Is Required for Developmental Stage-Specific Silencing of Oncofetal Genes in Hematopoietic Stem/Progenitor Cells

Motohiko Oshima, PhD, Satoru Miyagi, PhD, Shuhei Koide, George Russel Wendt, BS, Nagisa Hasegawa, MD, Shogo Yabata, Changshan Wang, PhD, Yutaka Suzuki, PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2900.
https://doi.org/10.1182/blood.V124.21.2900.2900
Published: 2014
Journal Articles

Histone Acetylation Mediated by Brd1 Is Crucial for Cd8 Gene Activation during Early Thymocyte Development

Yuta Mishima, PhD, Changshan Wang, PhD, Satoru Miyagi, PhD, Atsunori Saraya, MS, Hiroyuki Hosokawa, PhD, Naoto Yamaguchi, PhD, Toshinori Nakayama, MD PhD, Haruhiko Koseki, MD PhD, Ichiro Taniuchi, MD PhD, Atsushi Iwama, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1576.
https://doi.org/10.1182/blood.V124.21.1576.1576
Published: 2014