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Carsten Riether, PhD
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Journal Articles

Splenic CD24 low Red Pulp Macrophages Provide an Alternate Niche for Chronic Myeloid Leukemia Stem Cells

Michael A Amrein, MD PhD, Elias D Bührer, MD PhD, Stefan Forster, MD, Stephan Isringhausen, Christian M Schürch, MD PhD, Salil S. Bhate, MMath, Mohamad Al Sayed, PhD, Cesar Nombela Arrieta, PhD, Ramin Radpour, PhD, Carsten Riether, PhD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1634.
https://doi.org/10.1182/blood-2019-126593
Published: 2019
Journal Articles

Targeting CD70 with Cusatuzumab Eliminates Acute Myeloid Leukemia Stem Cells in Humans

Adrian F Ochsenbein, MD, Thomas Pabst, MD, Sabine Höpner, PhD, Vera Ulrike Bacher, Magdalena Hinterbrandner, Msc, Yara Banz, Rouven Müller, MD, Markus G. Manz, Prof.Dr.MD, Walid Gharib, David Francisco, Rémy Bruggmann, PhD, Luc Van Rompaey, PhD, Mahan Moshir, MSc, Tim Delahaye, MSc, Domenica Gandini, Ellen Erzeel, Anna Hultberg, PhD, Samson Fung, MD, Hans De Haard, Nicolas Leupin, Carsten Riether, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 234.
https://doi.org/10.1182/blood-2019-129916
Published: 2019
Journal Articles

CD93-Signaling Regulates Self-Renewal and Proliferation of Chronic Myeloid Leukemia Stem Cells in Mice and Humans and Might be a Promising Target for Treatment

Carsten Riether, PhD, Ramin Radpour, PhD, Chantal L. Bachmann, MSc, Christian M Schürch, MD PhD, Miroslav Arambasic, PhD, Gabriela M Baerlocher, MD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 187.
https://doi.org/10.1182/blood-2019-127864
Published: 2019
Journal Articles

The Combination of the BCL-2 Antagonist Venetoclax with the CD70-Targeting Antibody Cusatuzumab Synergistically Eliminates Primary Human Leukemia Stem Cells

Carsten Riether, PhD, Tanja Chiorazzo, PhD, Amy J. Johnson, PhD, Christina Diane Drenberg, PhD, Khaja Waheeduddin Syed, BPharm, MS, Mahan Moshir, MSc, Anna Hultberg, PhD, Nicolas Leupin, Hans De Haard, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3918.
https://doi.org/10.1182/blood-2019-127464
Published: 2019
Journal Articles

Argx-110 Targeting CD70, in Combination with Azacitidine, Shows Favorable Safety Profile and Promising Anti-Leukemia Activity in Newly Diagnosed AML Patients in an Ongoing Phase 1/2 Clinical Trial

Adrian F Ochsenbein, MD, Carsten Riether, PhD, Ulrike Bacher, Rouven Müller, MD, Sabine Höpner, PhD, Yara Banz, Magdalena Hinterbrandner, Msc, Mario Bargetzi, MD, Markus G. Manz, MD, Luc Van Rompaey, PhD, Mahan Moshir, MSc, Tim Delahaye, MSc, Domenica Gandini, MD PhD, Ellen Erzeel, Anna Hultberg, PhD, Samson Fung, MD, Hans De Haard, PhD, Nicolas Leupin, MD, Thomas Pabst, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2680.
https://doi.org/10.1182/blood-2018-99-118302
Published: 2018
Journal Articles

Blocking CD70/CD27 Signaling in Combination with Hypomethylating Agents Eradicates Human CD34 + AML Stem and Progenitor Cells in Vitro and In Vivo

Magdalena Hinterbrandner, Msc, Nils Maria Kallen, Ursina Lüthi, Thomas Pabst, MD, Luc Van Rompaey, PhD, Nicolas Leupin, MD, Hans De Haard, PhD, Adrian F Ochsenbein, MD, Carsten Riether, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2652.
https://doi.org/10.1182/blood.V130.Suppl_1.2652.2652
Published: 2017
Journal Articles

Splenic Red Pulp Macrophages Provide a Secondary Stem Cell Niche for Chronic Myeloid Leukemia Stem Cells

Elias D Bührer, MD, Michael A Amrein, MD, Stephan Isringhausen, Cesar Nombela-Arrieta, Carsten Riether, PhD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2861.
https://doi.org/10.1182/blood.V130.Suppl_1.2861.2861
Published: 2017
Journal Articles

The Traf2 and Nck-Interacting Kinase Is a Conserved Regulator of Self-Renewal in Hematopoietic and Leukemia Stem Cells

Michael A Amrein, MD, Elias D Bührer, MD, Carla Ruckstuhl, PhD, Sabine Höpner, PhD, Carsten Riether, PhD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1137.
https://doi.org/10.1182/blood.V130.Suppl_1.1137.1137
Published: 2017
Journal Articles

CD70/CD27 Signaling Mediates Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors By Compensatory Activation of the Wnt Pathway

Carsten Riether, PhD, Christian M. Schürch, MD PhD, Ramin Radpour, PhD, Magdalena Hinterbrandner, Anne-Laure Huguenin, Adrian F. Ochsenbein, Prof. MD
Journal: Blood
Blood (2014) 124 (21): 400.
https://doi.org/10.1182/blood.V124.21.400.400
Published: 2014