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Journal Articles

Increased Frequency of TOX + CD39 + TIGIT + CD73 - CD8 + T Cells in Patients with Newly Diagnosed AML

Franziska Brauneck, MD, Christin Ackermann, PhD, Nils Wildner, Jasmin Wellbrock, PhD, Carsten Bokemeyer, MD, Julian Schulze zur Wiesch, MD, Walter Fiedler, MD

Blood (2020) 136 (Supplement 1): 36.

https://doi.org/10.1182/blood-2020-139917

Published: 2020

Journal Articles

Blockade of Mer By the Small Molecule Inhibitor R992 Inhibits Multiple Myeloma and Its Associated Bone Disease By Restoring the Perturbed Bone Homeostasis

Janik Engelmann, Isabel Ben Batalla, PhD, Hanna Taipaleenmäki, PhD, Kristoffer Riecken, PhD, Victoria Gensch, Sarina Paesler, Nikolaus Berenbrok, Maria Elena Vargas, Jonas Waizenegger, MD, Boris Fehse, PhD, Klaus Pantel, MD, PhD, Ihab S Darwish, PhD, Somasekhar Bhamidipati, PhD, Esteban Masuda, PhD, Carsten Bokemeyer, MD, PhD, Eric Hesse, MD, PhD, Sonja Loges, MD, PhD

Blood (2018) 132 (Supplement 1): 1922.

https://doi.org/10.1182/blood-2018-99-118273

Published: 2018

Journal Articles

Therapeutic Potential of Axl Blockade in BCR-ABL Negative Myeloproliferative Neoplasms (MPN)

Antonia Beitzen-Heineke, MD, Isabel Ben Batalla, PhD, Nikolaus Berenbrok, Sarina Paesler, Victoria Gensch, Gunhild von Amsberg, Philippe Schafhausen, MD, Kristoffer Riecken, PhD, Thomas Fischer, MD, Klaus Pantel, MD, PhD, Carsten Bokemeyer, MD, PhD, Sonja Loges, MD, PhD

Blood (2018) 132 (Supplement 1): 3063.

https://doi.org/10.1182/blood-2018-99-118175

Published: 2018

Journal Articles

BET-Inhibition By JQ1 Promotes Proliferation and Self-Renewal Capacity of Hematopoietic Stem Cells

Mark Wroblewski, PhD, Marina Scheller-Wendorff, PhD, Raimund Bauer, PhD, Florian Udonta, Jara Schlichting, Lin Zhao, MD, Isabel Ben Batalla, PhD, Victoria Gensch, Marek Wanior, Hanna Taipaleenmäki, PhD, Simona Bolamperti, PhD, Zeynab Najafova, PhD, Klaus Pantel, MD PhD, Carsten Bokemeyer, MD PhD, Eric Hesse, MD PhD, Stefan Knapp, PhD, Steven Johnsen, PhD, Sonja Loges, MD PhD

Blood (2017) 130 (Supplement 1): 1900.

https://doi.org/10.1182/blood.V130.Suppl_1.1900.1900

Published: 2017

Journal Articles

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

Arne Velthaus, Kerstin Cornils, PhD, Saskia Grüb, MSc, Hauke Stamm, MSc, Daniel Wicklein, PhD, Carsten Bokemeyer, MD, Michael Heuser, MD, Sabine Windhorst, PhD, Walter Fiedler, MD, Jasmin Wellbrock, PhD

Blood (2016) 128 (22): 1662.

https://doi.org/10.1182/blood.V128.22.1662.1662

Published: 2016

Journal Articles

Phase II Results of Ara-C and Idarubicin in Combination with the Selective Inhibitor of Nuclear Export (SINE) Compound Selinexor (KPT-330) in Patients with Relapsed or Refractory AML

Walter Fiedler, Michael Heuser, MD, Jörg Chromik, Felicitas Thol, Carsten Bokemeyer, MD, Susann Theile, Isabell Lebkuechner, Anne L. Kranich

Blood (2016) 128 (22): 341.

https://doi.org/10.1182/blood.V128.22.341.341

Published: 2016

Journal Articles

Opposite Effects of Bruton Tyrosine Kinase (BTK) Inhibitor Therapy with Ibrutinib and FCR Chemo-Immunotherapy on the Normal B Lymphocyte Repertoire in Patients with Chronic Lymphocytic Leukemia

Simon Schliffke, MD, Mariela Sivina, PhD, Ekaterina Kim, PhD, Benjamin Thiele, MD, Nuray Akyüz, PhD, Clemens Falker-Gieske, PhD, Toni Thenhausen, Artus Krohn-Grimberghe, PhD, Carsten Bokemeyer, MD, Nitin Jain, MD, Zeev Estrov, MD, Alessandra Ferrajoli, MD, William G. Wierda, MD PhD, Michael J. Keating, MD, Jan A. Burger, MD PhD, Mascha Binder, MD

Blood (2016) 128 (22): 4402.

https://doi.org/10.1182/blood.V128.22.4402.4402

Published: 2016

Journal Articles

Expression of Novel Immune Checkpoint Molecules PVR and PVRL2 Confers a Negative Prognosis to Patients with Acute Myeloid Leukemia and Their Blockade Augments T-Cell Mediated Lysis of AML Cells Alone or in Combination with the BiTE ® Antibody Construct AMG 330

Hauke Stamm, MSc, Felix Klingler, cand. MD, Daniela Pende, MD, Eik Vettorazzi, MSc, Michael Heuser, MD, Ulrike Mock, PhD, Carsten Bokemeyer, MD, Roman Kischel, MD, Sabine Stienen, PhD, Matthias Friedrich, PhD, Michael Lutteropp, PhD, Dirk Nagorsen, MD, Jasmin Wellbrock, PhD, Walter Fiedler, MD

Blood (2015) 126 (23): 789.

https://doi.org/10.1182/blood.V126.23.789.789

Published: 2015

Journal Articles

BGB324 Inhibits BCR-ABL TKI-Resistant Chronic Myeloid Leukemia

Blood (2015) 126 (23): 1569.

https://doi.org/10.1182/blood.V126.23.1569.1569

Published: 2015

Journal Articles

Expression and Release of Platelet Protein Disulfide (PDI) Isomerase Is Increased in Patients with Hemophilia a

Florian Langer, Minna Voigtländer, Katharina Holstein, Brigitte Spath, Walter Fiedler, MD, Carsten Bokemeyer, MD

Blood (2015) 126 (23): 1085.

https://doi.org/10.1182/blood.V126.23.1085.1085

Published: 2015

Journal Articles

Optimization of Rituximab for Treatment of DLBCL in Young, High-Risk Patients-Results of the Dense-R-CHOEP Trial of the German High-Grade Lymphoma Study Group

Norbert Schmitz, MD PhD, Maike Nickelsen, MD, Marita Ziepert, PhD, Mathias Haenel, MD, Andreas Viardot, MD, Martin H. Dreyling, MD PhD, Peter Borchmann, MD, Carsten Bokemeyer, MD, Christian Peschel, MD, Hans-Heinrich Wolf, MD, Rolf Mahlberg, MD, Michael Pfreundschuh, MD, Bertram Glass, MD

Blood (2015) 126 (23): 474.

https://doi.org/10.1182/blood.V126.23.474.474

Published: 2015

Journal Articles

Selinexor, ARA-C and Idarubicin: An Effective and Tolerable Combination in Patients with Relapsed/Refractory AML: A Multicenter Phase II Study

Walter Fiedler, MD, Jörg Chromik, Maxim Kebenko, Felicitas Thol, MD, Arne Trummer, MD, Chirstoph Schünemann, Christian H. Brandts, MD, Anne Köhler, Vera Schlipfenbacher, Carsten Bokemeyer, MD, Susann Theile, Anne L. Kranich, Michael Heuser, MD

Blood (2015) 126 (23): 3789.

https://doi.org/10.1182/blood.V126.23.3789.3789

Published: 2015

Journal Articles

BGB324 Represents an Axl and BCR-ABL1 Inhibitor with Activity in the T315I Mutant

Blood (2014) 124 (21): 4512.

https://doi.org/10.1182/blood.V124.21.4512.4512

Published: 2014

Journal Articles

Axl Represents a Therapeutic Target In T315I-Mutated and WT Chronic Myeloid Leukemia

Blood (2013) 122 (21): 1469.

https://doi.org/10.1182/blood.V122.21.1469.1469

Published: 2013

Journal Articles

Expression Of Hedgehog Pathway Mediator Gli2 Represents a Clinically Negative Prognostic Marker In Acute Myeloid Leukemia and Its Inhibitor GANT61 Exerts Anti-Leukemic Effects In Vitro

Jasmin Wellbrock, Ph.D., Julian M Koehler, Katharina Wagner, MD, Emily Latuske, M.Sc., Hauke Stamm, M.Sc., Eik Vettorazzi, M.Sc., Gabi Vohwinkel, M.Sc., Marianne Klokow, Roswitha Kuhling-Thees, Sonja Loges, MD, Ph.D, Michael Amling, MD, Carsten Bokemeyer, MD, Michael Heuser, MD, Juergen Krauter, MD, Walter Fiedler, MD

Blood (2013) 122 (21): 53.

https://doi.org/10.1182/blood.V122.21.53.53

Published: 2013

Journal Articles

BCR-ABL Cooperates With a “Telomere-Associated Secretory Phenotype” (TASP) To Facilitate Malignant Proliferation Of Hematopoietic Stem Cells

Tim H. Brümmendorf, MD, Nora Pällmann, Michael Preukschas, Doris Steinemann, PD Dr. rer. nat., Winfried Hofmann, Dr. rer. nat., Anne Gompf, Karl L. Rudolph, Carsten Bokemeyer, MD, Steffen Koschmieder, Andreas Schuppert, Stefan Balabanov, Melanie Braig

Blood (2013) 122 (21): 3976.

https://doi.org/10.1182/blood.V122.21.3976.3976

Published: 2013

Journal Articles

Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes

Gabriela B. Iwanski, MD, Nils H. Thoennissen, MD, Joy Nakitandwe, BSc, MSc, PhD, Patricia Lin, Norihiko Kawamata, Rahul Nahar, Parham Ramezani-Rad, Shann-Ching Chen, Sheila Shurtleff, PhD, Daniel Nowak, MD, Christian Ruckert, Martin Dugas, MD, Carsten Bokemeyer, MD, Grazia Fazio, Andrea Biondi, Professor, MD, Giovanni Cazzaniga, PhD, James R. Downing, MD, Markus Müschen, H. Phillip Koeffler, MD

Blood (2010) 116 (21): 3231.

https://doi.org/10.1182/blood.V116.21.3231.3231

Published: 2010

Journal Articles

A Phase I/II Study Combining Sunitinib with Standard Ara-C/Daunorubicin Chemotherapy In Patients 60 Years or Older with FLT3 Mutated AML

Walter Fiedler, MD, Jürgen Krauter, MD, Katharina Götze, Helmut R. Salih, MD, Carsten Bokemeyer, MD, Daniela Spaeth, Konstanze Döhner, Hartmut Döhner, MD, Richard F. Schlenk, MD

Blood (2010) 116 (21): 3285.

https://doi.org/10.1182/blood.V116.21.3285.3285

Published: 2010

Journal Articles

Current Practice In Diagnosis and Treatment of Chemotherapy-Induced Anemia In Five European Countries – A Patient Record Study

Yves Beguin, MD, PhD, Matti Aapro, MD, Carsten Bokemeyer, MD, John Glaspy, MD, Michael Hedenus, MD, Timothy James Littlewood, MD, FRCP, Heinz Ludwig, MD, Anders Österborg, MD, Daniell Mitchell, PhD

Blood (2010) 116 (21): 1512.

https://doi.org/10.1182/blood.V116.21.1512.1512

Published: 2010

Journal Articles

Empirical Vs. Prophylactic Antifungal Strategies: Comparison of Effectiveness In High Risk AML Patients at a Tertiary Cancer Center

Dennis Gutmann, Jan Felix Kersten, Philippe Schafhausen, MD, Tim H. Brummendorf, MD, Martin Trepel, MD, PhD, Carsten Bokemeyer, MD, Jens Panse, MD

Blood (2010) 116 (21): 1729.

https://doi.org/10.1182/blood.V116.21.1729.1729

Published: 2010

NARROW

Increased Frequency of TOX + CD39 + TIGIT + CD73 - CD8 + T Cells in Patients with Newly Diagnosed AML

Blockade of Mer By the Small Molecule Inhibitor R992 Inhibits Multiple Myeloma and Its Associated Bone Disease By Restoring the Perturbed Bone Homeostasis

Therapeutic Potential of Axl Blockade in BCR-ABL Negative Myeloproliferative Neoplasms (MPN)

BET-Inhibition By JQ1 Promotes Proliferation and Self-Renewal Capacity of Hematopoietic Stem Cells

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

Phase II Results of Ara-C and Idarubicin in Combination with the Selective Inhibitor of Nuclear Export (SINE) Compound Selinexor (KPT-330) in Patients with Relapsed or Refractory AML

Opposite Effects of Bruton Tyrosine Kinase (BTK) Inhibitor Therapy with Ibrutinib and FCR Chemo-Immunotherapy on the Normal B Lymphocyte Repertoire in Patients with Chronic Lymphocytic Leukemia

Expression of Novel Immune Checkpoint Molecules PVR and PVRL2 Confers a Negative Prognosis to Patients with Acute Myeloid Leukemia and Their Blockade Augments T-Cell Mediated Lysis of AML Cells Alone or in Combination with the BiTE ® Antibody Construct AMG 330

BGB324 Inhibits BCR-ABL TKI-Resistant Chronic Myeloid Leukemia

Expression and Release of Platelet Protein Disulfide (PDI) Isomerase Is Increased in Patients with Hemophilia a

Optimization of Rituximab for Treatment of DLBCL in Young, High-Risk Patients-Results of the Dense-R-CHOEP Trial of the German High-Grade Lymphoma Study Group

Selinexor, ARA-C and Idarubicin: An Effective and Tolerable Combination in Patients with Relapsed/Refractory AML: A Multicenter Phase II Study

BGB324 Represents an Axl and BCR-ABL1 Inhibitor with Activity in the T315I Mutant

Axl Represents a Therapeutic Target In T315I-Mutated and WT Chronic Myeloid Leukemia

Expression Of Hedgehog Pathway Mediator Gli2 Represents a Clinically Negative Prognostic Marker In Acute Myeloid Leukemia and Its Inhibitor GANT61 Exerts Anti-Leukemic Effects In Vitro

BCR-ABL Cooperates With a “Telomere-Associated Secretory Phenotype” (TASP) To Facilitate Malignant Proliferation Of Hematopoietic Stem Cells

Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes

A Phase I/II Study Combining Sunitinib with Standard Ara-C/Daunorubicin Chemotherapy In Patients 60 Years or Older with FLT3 Mutated AML

Current Practice In Diagnosis and Treatment of Chemotherapy-Induced Anemia In Five European Countries – A Patient Record Study

Empirical Vs. Prophylactic Antifungal Strategies: Comparison of Effectiveness In High Risk AML Patients at a Tertiary Cancer Center

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American Society of Hematology

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American Society of Hematology

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