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Journal Articles

Weekly Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab (wKRd-D) Combination Therapy in Newly Diagnosed Multiple Myeloma: Final Results from a Clinical and Correlative Phase 2 Study

Ola Landgren, MD PhD, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Hani Hassoun, MD, Carlyn Tan, MD, Urvi A Shah, MD, Sydney X. Lu, MD PhD, Benjamin Diamond, MD, Meghan Salcedo, RN, Kelly Werner, RN, Jenna Rispoli, RN, Julia Caple, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Isabel Concepcion, NP, Ciardello Amanda, MS, Aisara Chansakul, BS, Julia Schlossman, BA, Elizabet Tavitian, BS, Tala Shekarkhand, BS, Angela Harrison, MS, Casey Piacentini, BS, Even H Rustad, MD PhD, Venkata Yellapantula, PhD, Francesco Maura, MD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Katie Thoren, Kazunori Murata, PhD, Lakshmi Ramanathan, PhD, Maria E. Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Andriy Derkach, PhD, Sergio A. Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7.
https://doi.org/10.1182/blood-2020-142466
Published: 2020
Journal Articles

Long-Term Sustained Minimal Residual Disease (MRD) Negativity in Patients with Multiple Myeloma Treated with Continuous Lenalidomide Maintenance Therapy: A Clinical and Correlative Phase 2 Study

Benjamin Diamond, MD, Neha Korde, MD, Alexander M. Lesokhin, MD, Eric L Smith, MDPhD, Urvi A Shah, MD, Sham Mailankody, MBBS, Malin Hultcrantz, MD PhD, Hani Hassoun, MD, Sydney X. Lu, MD PhD, Carlyn Tan, MD, Donna Massey, MSN, RN, Meghan Salcedo, BSN, RN, Victoria Diab, RN, Kelly Werner, RN, Jenna Rispoli, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Julia Schlossman, BA, Aisara Chansakul, BS, Angela Harrison, MS, Amanda Kathryn Ciardiello, Elizabet Tavitian, BS, Tala Shekarkhand, BS, Casey Piacentini, BS, Even H Rustad, MD PhD, Venkata D Yellapantula, Francesco Maura, MD, Tim J Peterson, PharmD, Andriy Derkach, PhD, Sean Devlin, PhD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan L. Shah, MDMS, Oscar B Lahoud, MD, Katie Thoren, Kazunori Murata, Lakshmi Ramanathan, PhD, Maria E. Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sergio A. Giralt, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-140152
Published: 2020
Journal Articles

Frontline Sequential Immunochemotherapy Plus Lenalidomide for Mantle Cell Lymphoma Incorporating MRD Evaluation: Phase II, Investigator-Initiated, Single-Center Study

Zachary D. Epstein-Peterson, MD, Connie Lee Batlevi, MDPhD, Philip Caron, MD PhD, Ahmet Dogan, MD PhD, Pamela Drullinsky, MD, John Gerecitano, MD PhD, Audrey Hamilton, MD, Paul A. Hamlin, MD, Caleb Ho, MD, Allison P. Jacob, Leana Laraque, BA, Matthew J Matasar, MD, Alison J. Moskowitz, MD, Craig H. Moskowitz, MD, Chelsea D Mullins, BS, Colette Owens, MD, Gilles Salles, Heiko Schöder, MD, David J. Straus, MD, Anas Younes, Andrew D Zelenetz, MD PhD, Anita Kumar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-136565
Published: 2020
Journal Articles

Long-Term Sustained Minimal Residual Disease (MRD) Negativity in Multiple Myeloma Patients Treated with Lenalidomide Maintenance Therapy: A Clinical and Correlative Phase 2 Study

Ola Landgren, MD PhD, Donna Mastey, RN, Alexander M. Lesokhin, MD, Eric L Smith, MD PhD, Urvi A Shah, MD, Sham Mailankody, MBBS, Malin Hultcrantz, MD PhD, Hani Hassoun, MD, Sydney X Lu, MD PhD, Meghan Salcedo, RN, Victoria Diab, RN, Kelly Werner, RN, Jenna Rispoli, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Julia Schlossman, BA, Aisara Chansakul, BS, Angela Harrison, MS, Amanda Ciardiello, BS, Elizabeth Tavitian, BS, Tala Shekarkhand, BS, Even Rustad, MD, Venkata Yellapantula, PhD, Francesco Maura, MD, Tim J Peterson, PharmD, Sean M. Devlin, PhD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Katie Thoren, PhD, Kazunori Murata, PhD, Lakshmi Ramanathan, PhD, Maria E Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sergio Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3127.
https://doi.org/10.1182/blood-2019-125842
Published: 2019
Journal Articles

Annotation of Somatic Genomic Variants in Hematologic Diseases Using OncoKB, a Precision Oncology Knowledgebase

Sarah P. Suehnholz, PhD, Ritika Kundra, MS, Mikhail Roshal, MD PhD, Wenbin Xiao, MD PhD, Kseniya Petrova-Drus, MD PhD, Mariko Yabe, MD PhD, Caleb Ho, MD, Hongxin Zhang, MS, David Knorr, MD PhD, Linde A Miles, PhD, Scott Millman, MD PhD, Moriah H. Nissan, PhD, Lindsay M. LaFave, PhD, Maria E Arcila, MD, Michael F. Berger, PhD, Ahmet Zehir, PhD, Ryan Ptashkin, MS, Jianjiong Gao, PhD, David B. Solit, MD, Ahmet Dogan, MD PhD, Ross L. Levine, MD, Nikolaus Schultz, PhD, Debyani Chakravarty, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2148.
https://doi.org/10.1182/blood-2019-125068
Published: 2019
Journal Articles

Weekly Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab (wKRd-D) Combination Therapy Provides Unprecedented MRD Negativity Rates in Newly Diagnosed Multiple Myeloma: A Clinical and Correlative Phase 2 Study

Ola Landgren, MD PhD, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Hani Hassoun, MD, Eric L Smith, MD PhD, Urvi A Shah, MD, Sydney X Lu, MD PhD, Donna Mastey, RN, Meghan Salcedo, RN, Victoria Diab, RN, Kelly Werner, RN, Jenna Rispoli, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, NP, Angela Harrison, MS, Aisara Chansakul, BS, Even H Rustad, MD, Venkata Yellapantula, PhD, Francesco Maura, MD, Heather J Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan Shah, MD, Oscar B Lahoud, MD, Katie Thoren, PhD, Kazunori Murata, PhD, Lakshmi Ramanathan, PhD, Maria E Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sean M. Devlin, PhD, Sergio Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 862.
https://doi.org/10.1182/blood-2019-126378
Published: 2019
Journal Articles

Plasma Cell Myeloma Residual Disease Quantitation Using a Next-Generation Sequencing-Based IGH Clonal Rearrangement Assay with the Aid of a "Spike-in" Clonal Sequence

Caleb Ho, MD, Mustafa Syed, MS, Wayne Yu, B.S, Kseniya Petrova-Drus, MD PhD, Jin Juan Yao, MD PhD, Christine Moung, MD, Jason Chang, MD, Jamal Benhamida, MD, Chad Vanderbilt, MD, Mikhail Roshal, MD PhD, Qi Gao, MLS, Lidia Maciag, BS, Meiyi Wang, BS, Yuanyuan Ma, BS, Even H Rustad, MD, Ying Huang, PhD, Kasey Hutt, PhD, Jeffrey E Miller, PhD, Ola Landgren, MD PhD, Khedoudja Nafa, PhD, Maria E Arcila, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3380.
https://doi.org/10.1182/blood-2019-127672
Published: 2019
Journal Articles

Next-Generation Sequencing-Based Assay Shows High Clonal Characterization Success Rate for Plasma Cell Neoplasms, and Concordance with Flow Cytometry in Minimal Residual Disease Detection

Caleb Ho, MD, Mustafa Syed, MS, Mikhail Roshal, MD PhD, Kseniya Petrova-Drus, MD PhD, Christine Moung, MD, Jin Juan Yao, MD PhD, Wayne Yu, B.S, Lidia Maciag, Ryma Benayed, PhD, Malin Hultcrantz, MD PhD, Ahmet Dogan, MD PhD, Khedoudja Nafa, PhD, Ola Landgren, MD PhD, Maria E Arcila, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4475.
https://doi.org/10.1182/blood-2018-99-115690
Published: 2018
Journal Articles

V(D)J Sequence Capture for DNA-Based Minimal Residual Disease Detection in Multiple Myeloma

Even H Rustad, MD, Malin Hultcrantz, MD PhD, Venkata D Yellapantula, Theresia Akhlaghi, BS, Caleb Ho, MD, Maria E Arcila, MD, Mikhail Roshal, MD PhD, Akshar Patel, BA, Sean M Devlin, PhD, Austin Jacobsen, Ying Huang, PhD, Jeffrey E Miller, PhD, Elli Papaemmanuil, PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4444.
https://doi.org/10.1182/blood-2018-99-113889
Published: 2018
Journal Articles

Bone Marrow-Based and Longitudinal Blood-Based MRD Tracking in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide and Dexamethasone (DKRd): A Correlative and Clinical Phase II Study

Ola Landgren, MD PhD, Katie Thoren, PhD, Malin Hultcrantz, MD PhD, Alexander M. Lesokhin, MD, Nikoletta Lendvai, MD PhD, Sham Mailankody, MBBS, Eric L. Smith, MD PhD, Hani Hassoun, MD, Sydney X. Lu, MD PhD, Donna Mastey, RN, Meghan Salcedo, RN, Victoria Diab, RN, Allison Sams, NP, Dennis Verducci, NP, Katie Jones, Angela Harrison, MS, Even H Rustad, MD, Venkata Yellapantula, PhD, Theresia Akhlaghi, BS, Heather J. Landau, MD, Michael Scordo, MD, David J. Chung, MD PhD, Gunjan L. Shah, MD MS, Oscar B Lahoud, MD, Maria E Arcila, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD, Sergio Giralt, MD, Neha Korde, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3281.
https://doi.org/10.1182/blood-2018-99-114311
Published: 2018
Journal Articles

Myeloid/Histiocytic Neoplasms Associated with Germ Cell Tumors Harbor Shared Genetic Abnormalities Indicating a Clonal Relationship, Unique Molecular Pathogenesis and Cellular Origin

Caleb Ho, MD, Yanming Zhang, MD, Umut Aypar, PhD, Mariko Yabe, MD PhD, Filiz Sen, MD, Maria E Arcila, MD, Ahmet Dogan, MD PhD, Kseniya Petrova-Drus, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3077.
https://doi.org/10.1182/blood-2018-99-115698
Published: 2018
Journal Articles

MRD-Response Driven Phase I/II Study for Newly Diagnosed Multiple Myeloma Patients Using Higher Doses of Twice-Weekly Carfilzomib (45 and 56 mg/m 2 ) in Combination with Lenalidomide and Dexamethasone

Neha Korde, MD, Donna Mastey, RN, Sham Mailankody, MBBS, Hani Hassoun, MD, Alexander M. Lesokhin, MD, Eric L. Smith, MD PhD, Nikoletta Lendvai, MDPhD, Malin Hultcrantz, MD PhD, Elizabet Tavitian, BS, Meghan Salcedo, RN, Allison Sams, NP, Victoria Diab, RN, David J. Chung, MDPhD, Michael Scordo, MD, Oscar B Lahoud, MD, Heather J. Landau, MD, Maria E Arcila, MD, Sergio Giralt, MD, Caleb Ho, MD, Mikhail Roshal, MD PhD, Sean M Devlin, PhD, Ahmet Dogan, MD PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1983.
https://doi.org/10.1182/blood-2018-99-117120
Published: 2018
Journal Articles

Allogeneic Stem Cell Transplantation Overcomes the Negative Prognostic Impact of TP53 Alterations in Mantle Cell Lymphoma

Richard J Lin, MDPhD, Caleb Ho, MD, Patrick Hilden, MS, Juliet Barker, MBBS, Sergio Giralt, MD, Paul A. Hamlin, MD, Ann A. Jakubowski, MDPhD, H.R. Castro-Malaspina, MD, Esperanza B. Papadopoulos, MD, Miguel-Angel Perales, MD, Craig S. Sauter, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4668.
https://doi.org/10.1182/blood-2018-99-113186
Published: 2018
Journal Articles

Use of Next Generation Sequencing and Single Nucleotide Polymorphism (SNP) Fingerprinting to Assess Post Transplant Engraftment Status

Abhinita S. Mohanty, MS, Juan Camilo Gomez-Gelvez, MD, Kseniya Petrova-Drus, Michael Zaidinski, Wei Wang, Jin Juan Yao, MD PhD, Caleb Ho, MD, Ahmet Zehir, PhD, Maria E. Arcila
Journal: Blood
Blood (2017) 130 (Supplement 1): 1943.
https://doi.org/10.1182/blood.V130.Suppl_1.1943.1943
Published: 2017
Journal Articles

Next Generation Sequencing (NGS) Based IGH and TCR Clonality Assays Provide Excellent Specificity and Sensitivity for Routine Clonal Characterization and Monitoring of Lymphoproliferative Disorders

Maria E. Arcila, Mustafa Syed, MS, Wayne Yu, B.S, Hannah Kim, B.S, JinYuan Yao, MD, Caleb Ho, MD, Kseniya Petrova-Drus, Mikhail Roshal, MDPhD, Jae H. Park, MD, Ola Landgren, MD PhD, Ahmet Dogan, MD PhD, Khedoudja Nafa, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4017.
https://doi.org/10.1182/blood.V130.Suppl_1.4017.4017
Published: 2017