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Bruce S Sachais, MD, PhD
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Journal Articles

Novel Diagnostic Assays for Heparin-Induced Thrombocytopenia

Adam Cuker, MD, MS, Ann H Rux, PhD, Jillian L Hinds, BS, May Dela Cruz, MD, Serge Yarovoi, PhD, Wei Yang, PhD, Barbara A. Konkle, MD, Gowthami M Arepally, MD, Steve P Watson, PhD, Douglas B. Cines, Bruce S Sachais, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 267.
https://doi.org/10.1182/blood.V120.21.267.267
Published: 2012
Journal Articles

Rational Design and Characterization of Platelet Factor 4 Antagonists

Bruce S Sachais, MD, PhD, Ann H Rux, PhD, Jillian L Hinds, BS, John J Rux, PhD
Journal: Blood
Blood (2010) 116 (21): 724.
https://doi.org/10.1182/blood.V116.21.724.724
Published: 2010
Journal Articles

Low Density Lipoprotein Apheresis Reduces PF4 on the Surface of Platelets: a Possible Protective Mechanism Against HIT

Yvette C Tanhehco, MD, PhD, Ann H Rux, PhD, Bruce S Sachais, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2530.
https://doi.org/10.1182/blood.V116.21.2530.2530
Published: 2010
Journal Articles

The Middle and Distal Carboxyl Terminal Domains of ADAMTS13 Are Critical for Docking ADAMTS13 to von Willebrand Factor.

Ping Zhang, MD, Pan Weilan, MD, Ann H. Rux, PhD, Bruce S. Sachais, MD, PhD, X. Long Zheng, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 332.
https://doi.org/10.1182/blood.V108.11.332.332
Published: 2006
Journal Articles

Elimination of Platelet Factor 4 (PF4) from Platelets Reduces Atherosclerosis and Increases HDL Cholesterol in C57Bl/6 and ApoE −/− Mice.

Bruce S. Sachais, MD, PhD, Tiffany Turrentine, BS, Jeanine M. Dawicki-McKenna, BS, Daniel J. Rader, MD, M. Anna Kowalska, PhD
Journal: Blood
Blood (2006) 108 (11): 418.
https://doi.org/10.1182/blood.V108.11.418.418
Published: 2006
Journal Articles

Dietary Hypercholesterolemia Enhances Heparin-Induced Thrombocytopenia/Thrombosis: A Prothrombotic Risk Factor in a Transgenic Mouse Model.

Michael P. Reilly, PhD, Scott K. Dessain, MD, PhD, Scott M. Taylor, MS, M. Anna Kowalska, PhD, Mortimer Poncz, MD, Bruce S. Sachais, MD, PhD, Douglas B. Cines, MD, Gowthami Arepally, MD, Kevin Jon Williams, MD, Steven E. McKenzie, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 56.
https://doi.org/10.1182/blood.V106.11.56.56
Published: 2005
Journal Articles

A Human Antibody, Cloned from a Patient with Heparin-Induced Thrombocytopenia, That Binds Heparin/Platelet Factor 4 Complexes.

Scott K. Dessain, MD, PhD, Katherine E. Rybinski, Sharad P. Adekar, MD, Lubica Rauova, MD, PhD, Bruce S. Sachais, MD, PhD, Steven E. McKenzie, MD, PhD, Michael P. Reilly, PhD
Journal: Blood
Blood (2005) 106 (11): 58.
https://doi.org/10.1182/blood.V106.11.58.58
Published: 2005
Journal Articles

Two Specific Domains on the Upper Surface of the αIib β Propeller Determine the Sensitivity of αIibβ3 for RGD-Containing Peptides.

Ramesh B. Basani, PhD, Michael A. Thornton, PhD, Bruce S. Sachais, MD, PhD, M. Anna Kowalska, PhD, William F. Degrado, PhD, Joel S. Bennett, MD, Mortimer Poncz, MD
Journal: Blood
Blood (2005) 106 (11): 2653.
https://doi.org/10.1182/blood.V106.11.2653.2653
Published: 2005
Journal Articles

The Platelet Specific Chemokine Platelet Factor 4 Induces Expression of E-Selectin in an NF-κ B Dependent Manner.

Bruce S. Sachais, MD, PhD, Peihong Ma, BS, Ann H. Rux, PhD, Guangyao Yu, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 3908.
https://doi.org/10.1182/blood.V104.11.3908.3908
Published: 2004