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Brian West
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Journal Articles

Recurrent Mutations in CCND3 Confer Clinical Resistance to FLT3 Inhibitors

Free
Catherine C. Smith, MD, Aaron D. Viny, MD MS, Evan S. Massi, BS, Cyriac Kandoth, PhD, Nicholas D. Socci, PhD, Henry Hsu, MD, Brian West, PhD, Gideon Bollag, PhD, Barry S. Taylor, PhD, Ross L. Levine, MD, Neil P. Shah
Journal: Blood
Blood (2015) 126 (23): 677.
https://doi.org/10.1182/blood.V126.23.677.677
Published: 2015
Journal Articles

The Combination of PLX3397, a Selective FLT3-ITD Inhibitor, and Decitabine, a Hypomethylating Agent, Demonstrates Benefit in AML Cell Lines in Vitro and in Vivo

Free
James Tsai, Elizabeth A Burton, PhD, Gaston Habets, PhD, Brian West, PhD, Paul Lin, MD, Henry Hsu, MD, Chao Zhang, PhD, Gideon Bollag, PhD
Journal: Blood
Blood (2014) 124 (21): 3743.
https://doi.org/10.1182/blood.V124.21.3743.3743
Published: 2014
Journal Articles

Preclinical and Clinical Resistance Mechanisms To The Investigational Selective FLT3 Inhibitor PLX3397 In FLT3-ITD+ Acute Myeloid Leukemia (AML)

Free
Catherine C Smith, MD, Kimberly Lin, BS, Elisabeth Lasater, PhD, Whitney Stewart, BS, Lauren E Damon, Andrew Kasarskis, PhD, Ali Bashir, PhD, Matthew Pendleton, Robert Sebra, Alexander E Perl, MD, Mai H Le, MD, Chao Zhang, PhD, Brian West, Ph.D., Neil P. Shah, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3938.
https://doi.org/10.1182/blood.V122.21.3938.3938
Published: 2013
Journal Articles

CSF1R Inhibition by PLX3397 in Patients with Relapsed or Refractory Hodgkin Lymphoma: Results From a Phase 2 Single Agent Clinical Trial

Free
Craig H. Moskowitz, MD, Anas Younes, MD, Sven de Vos, MD, PhD, R. Gregory Bociek, MD, Leo I. Gordon, MD, Thomas E. Witzig, MD, Randy D. Gascoyne, MD, Brian West, Ph.D., Keith Nolop, MD, Christian Steidl, MD
Journal: Blood
Blood (2012) 120 (21): 1638.
https://doi.org/10.1182/blood.V120.21.1638.1638
Published: 2012
Journal Articles

The Novel Inhibitor PLX3397 Effectively Inhibits FLT3-Mutant AML,

Free
Elizabeth Burton, Ph.D., Bernice Wong, Jiazhong Zhang, Ph.D., Brian West, Ph.D., Gideon Bollag, Ph.D., Gaston Habets, Ph.D., Allison Galanis, Hoa Nguyen, Omotayo Arowojolu, Trivikram Rajhowa, Mark J. Levis, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3632.
https://doi.org/10.1182/blood.V118.21.3632.3632
Published: 2011
Journal Articles

Novel Germ Line Mutations in the KRAS2 Gene Cause Noonan Syndrome and Deregulate Hematopoietic Cell Growth.

Free
Suzanne Schubbert, Martin Zenker, MD, Sara L. Rowe, Silke Bòˆll, Cornelia Klein, Ineke van der Burgt, MD, Luciana Musante, PhD, Hoa Nguyen, Brian West, PhD, Gideon Bollag, PhD, Charlotte M. Niemeyer, MD, Kevin M. Shannon, MD, Christian P. Kratz, MD
Journal: Blood
Blood (2005) 106 (11): 1602.
https://doi.org/10.1182/blood.V106.11.1602.1602
Published: 2005