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Brian J.P. Huntly, M.D., Ph.D.
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Journal Articles

Constitutively Activated FGFR3 Mutants Signal through PLCγ- Dependent and -Independent Pathways for Hematopoietic Transformation.

Jing Chen, Ph.D, Ifor R. Williams, M.D., Ph.D., Benjamin H. Lee, M.D., Ph.D., Nicole Duclos, Brian J.P. Huntly, M.D., Ph.D., Daniel J. Donoghue, Ph.D., D. Gary Gilliland, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1423.
https://doi.org/10.1182/blood.V104.11.1423.1423
Published: 2004
Journal Articles

TEL/PDGFβR Tyrosine Kinase Fusion Specifically Activates Myeloid Differentiation Programs, and Converts Lymphoid Progenitors into the Myeloid Lineage.

Hirokazu Shigematsu, M.D., Ph.D., Hiromi Iwasaki, M.D., Shin-ichi Mizuno, M.D., Ph.D., David W. Sternberg, M.D., Brian J.P. Huntly, M.D., Ph.D., D. Gary Gilliland, M.D., Ph.D., Koichi Akashi, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 387.
https://doi.org/10.1182/blood.V104.11.387.387
Published: 2004
Journal Articles

PKC412 Effectively Inhibits Constitutively Activated FGFR3 Mutants in Murine Leukemia Models and t(4;14) Myeloma Cell Lines.

Jing Chen, Ph.D., Benjamin H. Lee, M.D., Ph.D., Ifor R. Williams, M.D., Ph.D., Jeffery L. Kutok, M.D., Ph.D., Nicole Duclos, Sarah Cohen, Jennifer Adelsperger, Rachel Okabe, Allison Coburn, Sandra Moore, Brian J.P. Huntly, M.D., Ph.D., Constantine S. Mitsiades, M.D., Kenneth C. Anderson, M.D., James D. Griffin, M.D., Doriano Fabbro, Ph.D., D. Gary Gilliland, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2448.
https://doi.org/10.1182/blood.V104.11.2448.2448
Published: 2004
Journal Articles

PKC412 Inhibits the ZNF198-FGFR1 Fusion Tyrosine Kinase and Is Efficacious in Treatment of t(8;13)(p11;q12) Associated Stem Cell Myeloproliferative Disease.

Jing Chen, Ph.D., Daniel J. DeAngelo, M.D., Jeffery L. Kutok, M.D., Ph.D., Ifor R. Williams, M.D., Ph.D., Benjamin H. Lee, M.D., Ph.D., Martha Wadleigh, M.D., Nicole Duclos, Sarah Cohen, Jennifer Adelsperger, Rachel Okabe, Allison Coburn, Ilene Galinsky, Brian J.P. Huntly, M.D., Ph.D., Pamela Cohen, Ph.D., Thomas Meyer, Ph.D., Doriano Fabbro, Ph.D., Lolita Banerji, Ph.D., James D. Griffin, M.D., Sheng Xiao, M.D., Jonathan A. Fletcher, M.D., Richard M. Stone, M.D., D. Gary Gilliland, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2549.
https://doi.org/10.1182/blood.V104.11.2549.2549
Published: 2004