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Journal Articles

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Xing Fan, MD, Thomas Winkler, MD, Ronan Desmond, MD, Bogdan Dumitriu, MD, Danielle M. Townsley, MD MSc, Maria del Pilar Fernandez Ibanez, Fernanda Gutierrez-Rodrigues, PhD, Sophia Grasmeder, RN, Ma Evette Barranta, Diane Madey, Jennifer Lotter, Janet Valdez, Katherine R. Calvo, MD PhD, Colin Wu, PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 538.

https://doi.org/10.1182/blood-2018-99-112994

Published: 2018

Journal Articles

Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag

Thomas Winkler, MD, Danielle Townsley, MD, Ronan Desmond, MD FRCPath, Bogdan Dumitriu, MD, Sophia Grasmeder, RN, BSN, OCN, Neal S. Young, Cynthia E. Dunbar, MD

Blood (2016) 128 (22): 2682.

https://doi.org/10.1182/blood.V128.22.2682.2682

Published: 2016

Journal Articles

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Kohei Hosokawa, MDPhD, Sachiko Kajigaya, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Marie Desierto, Olga Rios, Barbara Weinstein, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2015) 126 (23): 3608.

https://doi.org/10.1182/blood.V126.23.3608.3608

Published: 2015

Journal Articles

Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery

Xin Zhao, MD PhD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Thomas Winkler, MD, Ronan Desmond, MD, Matthew J. Olnes, MD PhD, Harshraj Leuva, Bogdan Dumitriu, MD, Cynthia E. Dunbar, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3609.

https://doi.org/10.1182/blood.V126.23.3609.3609

Published: 2015

Journal Articles

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Kohei Hosokawa, MDPhD, Pawel Muranski, MD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Baoying Liu, PhD, Jared Knickelbein, MD, Keyvan Keyvanfar, BS, Bogdan Dumitriu, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Mariana J. Kaplan, MD, Robert B. Nussenblatt, MD, Austin John Barrett, MDFRCP,FRCPath, John O'Shea, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3613.

https://doi.org/10.1182/blood.V126.23.3613.3613

Published: 2015

Journal Articles

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates

Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Phillip Scheinberg, MD, Ronan Desmond, MD, FRCPath, Xingmin Feng, PhD, Olga Rios, RN, Barbara Weinstein, RN, Janet Valdez, PA-C, Thomas Winkler, MD, Marie Desierto, BS, Harshraj Leuva, MBBS, Colin Wu, PhD, Katherine R. Calvo, MD, PhD, Andre Larochelle, MD, PhD, Cynthia E. Dunbar, MD, Neal S. Young, MD

Blood (2015) 126 (23): LBA-2.

https://doi.org/10.1182/blood.V126.23.LBA-2.LBA-2

Published: 2015

Journal Articles

Acquired Aplastic Anemia: New Genetics, New Genomics

Neal S. Young, MD, Bogdan Dumitriu, MD, Seishi Ogawa, MD PhD

Blood (2014) 124 (21): SCI-21.

https://doi.org/10.1182/blood.V124.21.SCI-21.SCI-21

Published: 2014

Journal Articles

Telomere Length Is Associated with Specific Mutations and Mutation Classes in Patients with Acute Myeloid Leukemia

Justin M. Watts, MD, Bogdan Dumitriu, MD, Patrick Hilden, MS, Christina Chen, BS, Franck Rapaport, PhD, Ashwin Kishtagari, MD, Jihae Ahn, BS, Sean M. Devlin, PhD, Raajit K. Rampal, MD PhD, Ross L. Levine, MD, Neal S. Young, MD, Martin S. Tallman, MD

Blood (2014) 124 (21): 2280.

https://doi.org/10.1182/blood.V124.21.2280.2280

Published: 2014

Journal Articles

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Pawel Muranski, MD, Xingmin Feng, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Christopher S. Hourigan, MD PhD, John Barrett, MD, Neal S. Young, MD

Blood (2014) 124 (21): 2940.

https://doi.org/10.1182/blood.V124.21.2940.2940

Published: 2014

Journal Articles

Chronological Analysis of Clonal Evolution in Acquired Aplastic Anemia

Blood (2014) 124 (21): 253.

https://doi.org/10.1182/blood.V124.21.253.253

Published: 2014

Journal Articles

Telomere Elongation and Hematologic Improvement in Humans Treated with Androgens: A Prospective Clinical Trial of Danazol in Telomeropathies

Bogdan Dumitriu, MD, Danielle M. Townsley, MD, Christina Chen, BS, Rodrigo T. Calado, MD PhD, Phillip Scheinberg, MD, Neal S. Young, MD

Blood (2014) 124 (21): 258.

https://doi.org/10.1182/blood.V124.21.258.258

Published: 2014

Journal Articles

Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia

Muhamed Baljevic, MD, Bogdan Dumitriu, MD, Ju-Whei Lee, PhD, Elisabeth Paietta, PhD, Janis Racevskis, Christina Chen, BS, Eytan M. Stein, Robert E Gallagher, MD, Jacob M. Rowe, MD, Frederick R. Appelbaum, MD, Bayard L. Powell, MD, Richard A. Larson, Neal S. Young, MD, Martin S. Tallman, MD

Blood (2014) 124 (21): 2375.

https://doi.org/10.1182/blood.V124.21.2375.2375

Published: 2014

Journal Articles

Spectrum Of Genetic Alterations In Acquired Aplastic Anemia

Tetsuichi Yoshizato, MD, Bogdan Dumitriu, MD, Kohei Hosokawa, MD, PhD, Hideki Makishima, MD, PhD, Kenichi Yoshida, MD, Yusuke Okuno, Kenichi Chiba, BA, Hiroko Tanaka, BA, Yuichi Shiraishi, PhD, Yasunobu Nagata, MD, Takamasa Katagiri, PhD, Ayana Kon, MD, Michael J. Clemente, Masashi Sanada, MD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD, PhD, Shinji Nakao, MD, PhD, Neal S. Young, MD, Seishi Ogawa, MD, PhD

Blood (2013) 122 (21): 2464.

https://doi.org/10.1182/blood.V122.21.2464.2464

Published: 2013

Journal Articles

Alemtuzumab Achieved Durable Hematologic Response In Heavily Treated T-Large Granular Lymphocytosis Irrespective To STAT3 Mutation Or V-Beta Clone Size

Bogdan Dumitriu, MD, Phillip Scheinberg, MD, Sawa Ito, Nicole Stephens, BS, Yunce Muharrem, MD, Emily King, Sachiko Kajigaya, PhD, J. Joseph Melenhorst, PhD, Fariba Chinian, M.S., Keyvan Keyvanfar, BS, Minoo Battiwalla, MD, MS, Pawel Muranski, MD, Neal S. Young, MD, A. John Barrett

Blood (2013) 122 (21): 3705.

https://doi.org/10.1182/blood.V122.21.3705.3705

Published: 2013

Journal Articles

Translocation (8;21) Presenting As Severe Aplastic Anemia

Enkhtsetseg Purev, MD, Bogdan Dumitriu, MD, Neal S. Young, MD, Danielle Townsley, MD

Blood (2013) 122 (21): 4874.

https://doi.org/10.1182/blood.V122.21.4874.4874

Published: 2013

Journal Articles

Very Short Telomeres As a Novel Mechanism Of Donor-Cell Derived Leukemia After Cord Blood Transplantation

Bogdan Dumitriu, MD, Yasutaka Ueda, MD, PhD, Sachiko Kajigaya, PhD, Danielle Townsley, MD, Jennifer Cuellar Rodriguez, MD, Dennis D. Hickstein, M.D., Neal S. Young, MD

Blood (2013) 122 (21): 1245.

https://doi.org/10.1182/blood.V122.21.1245.1245

Published: 2013

Journal Articles

Clonal Evolution In Aplastic Anemia Is Driven By Chromosomal Instability Rather Than Mutations In Myeloid Malignancy Candidate Gene

Bogdan Dumitriu, MD, Xingmin Feng, PhD, Yasutaka Ueda, MD, PhD, Sachiko Kajigaya, PhD, Danielle Townsley, MD, Jun Zsu, PhD, Yoshi Wakabayashi, PhD, Yanqin Yang, MS, Delong Liu, PhD, Neal S. Young, MD

Blood (2013) 122 (21): 802.

https://doi.org/10.1182/blood.V122.21.802.802

Published: 2013

Journal Articles

Very Short Telomeres of Peripheral Blood Leukocytes Precede Clinical Progression to Myelodysplasia with Monosomy 7 in Aplastic Anemia Patients

Bogdan Dumitriu, MD, Yasutaka Ueda, MD, PhD, Sachiko Kajigaya, PhD, Danielle M. Townsley, MD, MSc, Neal S. Young, MD

Blood (2012) 120 (21): 1265.

https://doi.org/10.1182/blood.V120.21.1265.1265

Published: 2012

Journal Articles

Regulatory Mutations in GATA2 Associated with Aplastic Anemia

Danielle M. Townsley, MD, MSc, Amy Hsu, B.S., Bogdan Dumitriu, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2012) 120 (21): 3488.

https://doi.org/10.1182/blood.V120.21.3488.3488

Published: 2012

Journal Articles

Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

Phillip Scheinberg, MD, Danielle M. Townsley, MD, MSc, Bogdan Dumitriu, MD, Olga Rios, RN, Barbara Weinstein, RN, Minoo Battiwalla, MD, MS, Richard Childs, MD, Cynthia E. Dunbar, MD, A. John Barrett, MD, Colin O. Wu, Neal S. Young, MD

Blood (2012) 120 (21): 1259.

https://doi.org/10.1182/blood.V120.21.1259.1259

Published: 2012

NARROW

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Successful Treatment of a Diamond-Blackfan Anemia (DBA) Patient with Eltrombopag

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates

Acquired Aplastic Anemia: New Genetics, New Genomics

Telomere Length Is Associated with Specific Mutations and Mutation Classes in Patients with Acute Myeloid Leukemia

Altered microRNAs in T Cells from Patients with Acquired Aplastic Anemia

Chronological Analysis of Clonal Evolution in Acquired Aplastic Anemia

Telomere Elongation and Hematologic Improvement in Humans Treated with Androgens: A Prospective Clinical Trial of Danazol in Telomeropathies

Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia

Spectrum Of Genetic Alterations In Acquired Aplastic Anemia

Alemtuzumab Achieved Durable Hematologic Response In Heavily Treated T-Large Granular Lymphocytosis Irrespective To STAT3 Mutation Or V-Beta Clone Size

Translocation (8;21) Presenting As Severe Aplastic Anemia

Very Short Telomeres As a Novel Mechanism Of Donor-Cell Derived Leukemia After Cord Blood Transplantation

Clonal Evolution In Aplastic Anemia Is Driven By Chromosomal Instability Rather Than Mutations In Myeloid Malignancy Candidate Gene

Very Short Telomeres of Peripheral Blood Leukocytes Precede Clinical Progression to Myelodysplasia with Monosomy 7 in Aplastic Anemia Patients

Regulatory Mutations in GATA2 Associated with Aplastic Anemia

Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

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American Society of Hematology

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ASH Publications

American Society of Hematology

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