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Blake T Aftab
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Journal Articles

Expansion, Persistence and Pharmacodynamic Profile of ADI-001, a First-in-Class Allogeneic CD20-Targeted CAR Gamma Delta T Cell Therapy, in Patients with Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Monica A Moreno, Jackie Kennedy-Wilde, Andrew D Wrong, Nadine Jahchan, Francesco Galimi, Yining Ye, Rose Lai, Blake T Aftab
Journal: Blood
Blood (2023) 142 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2023-181919
Published: 2023
Journal Articles

ATA3219: A Potent Next-Generation Allogeneic Off-the-Shelf CD19-CAR T Therapy without the Need for Gene-Editing

C Pham, T Spindler, E Hwang, A Brito, Y Bulliard, Blake T Aftab, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9.
https://doi.org/10.1182/blood-2020-141262
Published: 2020
Journal Articles

CD46 Is Amplified in High-Risk Myeloma with Gain of Chromosome 1q and Selectively Targeted By a Novel Anti-CD46 Antibody-Drug Conjugate

Daniel W. Sherbenou, MD PhD, Blake T. Aftab, PhD, Yang Su, PhD, Christopher R. Behrens, PhD, Arun P. Wiita, MD PhD, Aaron C. Logan, MD PhD, Diego Acosta-Alvear, PhD, Byron C. Hann, MD PhD, Peter Walter, PhD, Xiaobo Wu, MD, John P. Atkinson, MD, Jeffrey L. Wolf, MD, Thomas G. Martin, III, MD, Bin Liu, PhD
Journal: Blood
Blood (2016) 128 (22): 384.
https://doi.org/10.1182/blood.V128.22.384.384
Published: 2016
Journal Articles

Tofacitinib Reverses Growth Promoting Effects of the Bone Marrow Stromal Environment Though Inhibition of JAK1/STAT3 Signaling in Multiple Myeloma

Christine Lam, Megan Murnane, M.Sc., Geoffrey A. Smith, Jack Taunton, PhD, Blake T. Aftab, PhD, Arun P. Wiita, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2098.
https://doi.org/10.1182/blood.V128.22.2098.2098
Published: 2016
Journal Articles

Defining Primary Marrow Microenvironment-Induced Synthetic Lethality and Resistance for 2,684 Approved Drugs Across Molecularly Distinct Forms of Multiple Myeloma

Megan Murnane, M.Sc., Eugen Dhimolea, PhD, Ruojing Li, BS, Megan A. Bariteau, BSc, Diamond D. Wheeler, BS, Rosemary J. Akhurst, PhD, Aaron C. Logan, MD PhD, Pamela Munster, MD, Arun Wiita, MD PhD, Thomas G. Martin, III, MD, Jeffrey L. Wolf, MD PhD, Jun O. Liu, PhD, Constantine S. Mitsiades, MD PhD, Blake T. Aftab, PhD
Journal: Blood
Blood (2015) 126 (23): 503.
https://doi.org/10.1182/blood.V126.23.503.503
Published: 2015
Journal Articles

Constitutive Vs. Stroma-Induced Kinase Dependencies in Myeloma Cells: Functional Mapping Using Small Molecule Inhibitors As Chemical Probes

Eugen Dhimolea, PhD, Emily King, Michal Sheffer, PhD, Yiguo Hu, MDPhD, Pallavi P. Awate, Subhashis Sarkar, PhD, Geoffrey M. Matthews, PhD, Megan Murnane, Megan A. Bariteau, BSc, Blake T. Aftab, PhD, Constantine S Mitsiades, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3709.
https://doi.org/10.1182/blood.V126.23.3709.3709
Published: 2015
Journal Articles

Pre-Clinical Activity of the Novel, First-in-Class p97 Inhibitor, CB-5083, in Multiple Myeloma

Blake T. Aftab, PhD, Daniel J Anderson, PhD, Ronan Le Moigne, PhD, Stevan Djakovic, PhD, Eugen Dhimolea, PhD, Megan Murnane, Emily King, Julie Rice, Steve Wong, Brajesh Kumar, PhD, Eduardo Valle, Mary-Kamala Menon, Szerenke Kiss von Soly, Jinhai Wang, PhD, Bing Yao, Ferdie Soriano, Martin Kampmann, PhD, Diego Alcost-Alvear, PhD, Marta Chesi, PhD, Leif Bergsagel, MD, F. Michael Yakes, PhD, Han-Jie Zhou, PhD, David Wustrow, PhD, Thomas G. Martin, MD, Jeffrey L. Wolf, Constantine S. Mitsiades, MD PhD, Mark Rolfe, PhD
Journal: Blood
Blood (2014) 124 (21): 4701.
https://doi.org/10.1182/blood.V124.21.4701.4701
Published: 2014
Journal Articles

Functional Mapping of Multiple Myeloma Kinome Using a Small Molecule Inhibitor Library

Eugen Dhimolea, PhD, Emily King, Michal Sheffer, PhD, Yiguo Hu, PhD, Subhashis Sarkar, PhD, Megan Murnane, Megan A. Bariteau, B.Sc., Blake T. Aftab, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3642.
https://doi.org/10.1182/blood.V124.21.3642.3642
Published: 2014
Journal Articles

Temporal Dynamics of Tumor-Microenvironment Interaction and Treatment Responses Revealed through Time-Lapse Compartment-Specific Bioluminescence Imaging: Translational implications

Eugen Dhimolea, PhD, Emily King, Efstathios Kastritis, MD, Douglas W. McMillin, PhD, Jake E. Delmore, B.Sc., Joseph M. Negri, B.Sc., Hannah M. Jacobs, B.Sc., Catriona A. Hayes, MD, Michal Sheffer, PhD, Yiguo Hu, PhD, Subhashis Sarkar, PhD, Richard W.J. Groen, PhD, Megan A. Bariteau, B.Sc., Blake T. Aftab, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2014) 124 (21): 276.
https://doi.org/10.1182/blood.V124.21.276.276
Published: 2014
Journal Articles

Genome-Scale Crispr-Cas9 Knockout Studies Reveal Mutifactorial and Functionally Overlapping Mechanisms of Myeloma Cell Resistance to Proteasome Inhibition

Michal Sheffer, PhD, Yiguo Hu, PhD, Ophir Shalem, PhD, Neville Sanjana, PhD, Eugen Dhimolea, PhD, Subhashis Sarkar, PhD, Megan A. Bariteau, B.Sc., Blake T. Aftab, PhD, Richard W.J. Groen, PhD, Feng Zhang, PhD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2014) 124 (21): 273.
https://doi.org/10.1182/blood.V124.21.273.273
Published: 2014