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Journal Articles

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Elisa Sala, MD, Francesca Biavasco, MD, Gabriele Bucci, PhD, Cristina Toffalori, PhD, Donatella Biancolini, PhD, Elena Antonini, MSc, Matteo Giovanni Carrabba, MD, Bernhard Gentner, MD, Cristina Tresoldi, MSc, Massimo Bernardi, MD, Dejan Lazarevic, MD, Giovanni Tonon, MD, Fabio Ciceri, MD, Luca Vago, MD PhD

Blood (2019) 134 (Supplement_1): 511.

https://doi.org/10.1182/blood-2019-124725

Published: 2019

Journal Articles

Extensive Metabolic Correction of Hurler Disease By Hematopoietic Stem Cell-Based Gene Therapy: Preliminary Results from a Phase I/II Trial

Bernhard Gentner, MD, Maria Ester Bernardo, MD PhD, Francesca Tucci, MD, Erika Zonari, PhD, Francesca Fumagalli, MD, Silvia Pontesilli, MD, Serena Acquati, PhD, Paolo Silvani, MD, Fabio Ciceri, MD, Attilio Rovelli, MD, Giancarlo La Marca, PhD, Rossella Parini, MD, Silvia Gregori, PhD, Eugenio Montini, PhD, Luigi Naldini, MD PhD, Alessandro Aiuti, MD PhD

Blood (2019) 134 (Supplement_1): 607.

https://doi.org/10.1182/blood-2019-128805

Published: 2019

Journal Articles

TEM-MM-101: A Phase I/IIa Dose Escalation Study Evaluating the Safety and Activity of Autologous CD34+ Enriched Hematopoietic Progenitor Cells Genetically Modified for Human Interferon-α2 in Multiple Myeloma Patients with Early Relapse after Intensive Front Line Therapy

Bernhard Gentner, MD, Francesca Farina, MD, Matteo Giovanni Carrabba, MD, Magda Marcatti, MD, Stefania Girlanda, MD, Gabriele Antonarelli, MD, Capotondo Alessia, PhD, Stefania Mazzoleni, PhD, Carlo Russo, MD, Luigi Naldini, MD PhD, Fabio Ciceri, MD

Blood (2019) 134 (Supplement_1): 2064.

https://doi.org/10.1182/blood-2019-123749

Published: 2019

Journal Articles

Longitudinal Tracking of Acute Myeloid Leukemia Stem Cells in Xenografts and Patients By microRNA Reporters and Single Cell RNA Sequencing

Matteo Maria Naldini, Gabriele Casirati, MD, Matteo Barcella, PhD, Stefano Beretta, PhD, Ivan Merelli, PhD, Carolina Caserta, Giacomo Desantis, PhD, Francesca Pavesi, MD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2019) 134 (Supplement_1): 916.

https://doi.org/10.1182/blood-2019-131167

Published: 2019

Journal Articles

Dissecting Ex Vivo Expansion of Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells By Single Cell RNA Sequencing

Matteo Maria Naldini, Gabriele Casirati, MD, Erika Zonari, PhD, Giacomo Desantis, PhD, Andrea Cammarata, PhD, Stefano Beretta, PhD, Ivan Merelli, PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 3343.

https://doi.org/10.1182/blood-2018-99-111879

Published: 2018

Journal Articles

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Nadia Foligno, Giacomo Desantis, PhD, Fabio Ciceri, MD, Davide Cittaro, PhD, Bernhard Gentner, MD

Blood (2018) 132 (Supplement 1): 2834.

https://doi.org/10.1182/blood-2018-99-115101

Published: 2018

Journal Articles

Distinct MiR-126 Expression Describes a Non-Genetic but Functional Intra-Tumoral Heterogeneity in Primary Human B-ALL and Can be Prospectively Used to Identify Aggressive Subclones in NSG Mice

Carolina Caserta, MS, Matteo Maria Naldini, MD, Silvia Nucera, MD, Davide Cittaro, Giacomo Desantis, Francesca Pavesi, MD, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2017) 130 (Supplement 1): 35.

https://doi.org/10.1182/blood.V130.Suppl_1.35.35

Published: 2017

Journal Articles

Incremental Innovation of Ex Vivo Hematopoietic Stem Cell Engineering to Expand Clinical Gene Therapy Applications

Erika Zonari, PhD, Giacomo Desantis, PhD, Carolina Petrillo, Oriana Meo, Samantha Scaramuzza, PhD, Maria Rosa Lidonnici, PhD, Anna Kajaste-Rudnitski, PhD, Fabio Ciceri, MD, Sarah Marktel, Alessandro Aiuti, MD PhD, Giuliana Ferrari, PhD, Luigi Naldini, MD PhD, Bernhard Gentner, MD

Blood (2016) 128 (22): 4707.

https://doi.org/10.1182/blood.V128.22.4707.4707

Published: 2016

Journal Articles

Human CD34 + Cells from Different Sources Disclose a Specific Stemness Signature

Maria Rosa Lidonnici, PhD, Annamaria Aprile, PhD, Marta Frittoli, MD, Giacomo Mandelli, PhD, Ylenia Paleari, PhD, Antonello Spinelli, Bernhard Gentner, MD, Matilde Zambelli, Cristina Parisi, Laura Bellio, MD, Elena Cassinerio, MD, Laura Zanaboni, MD, Maria Domenica Cappellini, Fabio Ciceri, MD, Sarah Marktel, MD, Giuliana Ferrari, PhD

Blood (2016) 128 (22): 4709.

https://doi.org/10.1182/blood.V128.22.4709.4709

Published: 2016

Journal Articles

microRNA-126 Orchestrates a Stem Cell-like Program in AML and B-ALL and Can be Exploited to Dissect Disease Heterogeneity

Francesca Pavesi, MD, Carolina Caserta, Silvia Nucera, MD, Matteo Maria Naldini, Andrea Cosentino, Giacomo Desantis, PhD, Jose Garcia-Manteiga, PhD, Matteo Carrabba, MD, Massimo Bernardi, MD, Luca Vago, MD PhD, Fabio Ciceri, MD, Bernhard Gentner, MD

Blood (2016) 128 (22): 736.

https://doi.org/10.1182/blood.V128.22.736.736

Published: 2016

Journal Articles

Intrinsic Molecular Features of Human Hematopoietic Stem Cells from Different Sources Define Their Specific Functional Properties

Maria Rosa Lidonnici, PhD, Annamaria Aprile, Marta Frittoli, MD, Giacomo Mandelli, PhD, Ylenia Paleari, PhD, Bernhard Gentner, MD, Laura Bellio, MD, Elena Cassinerio, MD, Laura Zanaboni, MD, Maria Domenica Cappellini, MD, Fabio Ciceri, MD, Sarah Marktel, MD, Giuliana Ferrari, PhD

Blood (2015) 126 (23): 3069.

https://doi.org/10.1182/blood.V126.23.3069.3069

Published: 2015

Journal Articles

Hoxa9/Meis1 Mediate Leukemic Programming through Microrna-155

Edith Schneider, M.Sc., Anna Staffas, PhD, Milijana Mirkovic-Hoesle, PhD, Bernhard Gentner, MD, Jens Ruschmann, Christian Buske, MD, Michael Heuser, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, R. Keith Humphries, MD PhD, Arefeh Rouhi, PhD, Florian Kuchenbauer, MD PhD, Lars Palmqvist, MD PhD

Blood (2014) 124 (21): 884.

https://doi.org/10.1182/blood.V124.21.884.884

Published: 2014

Journal Articles

Backtracking Leukemia Clonal Evolution from Post-Transplantation Relapse to Initial Diagnosis to Identify Founder Mutations and Mechanisms of Immune Evasion

Blood (2014) 124 (21): 1185.

https://doi.org/10.1182/blood.V124.21.1185.1185

Published: 2014

Journal Articles

Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance

Eric R. Lechman, PhD, Bernhard Gentner, MD, Peter van Galen, Stanley Wai-Kwong Ng, Kolja Eppert, PhD, Rene Marke, Liran Slush, MD, James A. Kennedy, MD PhD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, Veronique Voisin, PhD, Gary Bader, PhD, Mark D. Minden, MD, PhD, Jun Lu, PhD, Jean C.Y. Wang, MD PhD, Luigi Naldini, John E. Dick, PhD

Blood (2013) 122 (21): 1647.

https://doi.org/10.1182/blood.V122.21.1647.1647

Published: 2013

Journal Articles

The Challenge Of HSCs Procurement For Gene Therapy: Exploring Plerixafor As Mobilization Agent

Maria Rosa Lidonnici, PhD, Annamaria Aprile, MSc, Marta Claudia Frittoli, MD, Giacomo Mandelli, PhD, Bernhard Gentner, MD, Laura Bellio, MD, Elena Cassinerio, MD, Laura Zanaboni, MD, Maria Domenica Cappellini, MD, Silvano Rossini, MD, Fabio Ciceri, MD, Sarah Marktel, MD, Giuliana Ferrari, PhD

Blood (2013) 122 (21): 2901.

https://doi.org/10.1182/blood.V122.21.2901.2901

Published: 2013

Journal Articles

A Mechanistic Role For Mir-126, a Hematopoietic Stem Cell Microrna, In Acute Leukemias

Alice Giustacchini, PhD, Silvia Nucera, MD, Eric R. Lechman, PhD, Cristiana Fanciullo, Francesco E Boccalatte, Tiziana Plati, Anna Ranghetti, Luca Vago, MD, PhD, Massimo Bernardi, MD, Maurilio Ponzoni, MD, John E. Dick, PhD, Luigi Naldini, MD, PhD, Bernhard Gentner, MD

Blood (2013) 122 (21): 886.

https://doi.org/10.1182/blood.V122.21.886.886

Published: 2013

Journal Articles

Off-Tumor Target Expression Levels Do Not Predict CAR-T Cell Killing: A Foundation For The Safety Of CD44v6-Targeted T Cells

Monica Casucci, PhD, Benedetta Nicolis di Robilant, MSc, Laura Falcone, MSc, Barbara Camisa, BSc, Margherita Norelli, Bsc, Bernhard Gentner, MD, Pietro Genovese, PhD, Maurilio Ponzoni, MD, Aurore Saudemont, PhD, Claudio Bordignon, MD, Luigi Naldini, MD, PhD, Fabio Ciceri, MD, Gianpietro Dotti, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2013) 122 (21): 142.

https://doi.org/10.1182/blood.V122.21.142.142

Published: 2013

Journal Articles

CD44v6 Is Required For In Vivo Tumorigenesis Of Human AML and MM Cells: Role Of Microenvironmental Signals and Therapeutic Implications

Benedetta Nicolis di Robilant, MSc, Monica Casucci, PhD, Laura Falcone, MSc, Barbara Camisa, BSc, Bernhard Gentner, MD#, Luigi Naldini, MD, PhD#, Claudio Bordignon, MD, Fabio Ciceri, MD, Chiara Bonini, MD, Attilio Bondanza, MD, PhD

Blood (2013) 122 (21): 605.

https://doi.org/10.1182/blood.V122.21.605.605

Published: 2013

Journal Articles

Hematopoietic Stem Cell Expansion, without Exhaustion or Transformation, by Stable Microrna Antagonism in Vivo

Bernhard Gentner, MD, Alice Giustacchini, Eric Lechman, PhD, Peter van Galen, Francesco Boccalatte, Massimo Saini, John E. Dick, PhD, Luigi Naldini, MD, PhD

Blood (2012) 120 (21): 30.

https://doi.org/10.1182/blood.V120.21.30.30

Published: 2012

Journal Articles

Plerixafor Single Agent for Autologous Stem Cells Mobilization and Collection in Adult Thalassemic Patients: Towards the Assessment of the Suitable Hematopoietic Stem Cell Source for Gene Therapy of Beta-Thalassemia.

Marta Claudia Frittoli, MD, Bernhard Gentner, MD $, Maria Rosa Lidonnici, PhD, Annamaria Aprile, Laura Bellio, MD, Salvatore Gattillo, MD, Matilde Zambelli, Raffaella Milani, Elena Cassinerio, MD, Laura Zanaboni, MD, Silvano Rossini, MD, Maria Domenica Cappellini, MD, Fabio Ciceri, MD, Giuliana Ferrari, PhD, Sarah Marktel, MD

Blood (2012) 120 (21): 586.

https://doi.org/10.1182/blood.V120.21.586.586

Published: 2012

NARROW

Mapping the Evolution of the Mutational Landscape of Acute Myeloid Leukemia from Diagnosis to Post-Transplantation Relapse and Its Interplay with Immune Evasion Mechanisms

Extensive Metabolic Correction of Hurler Disease By Hematopoietic Stem Cell-Based Gene Therapy: Preliminary Results from a Phase I/II Trial

TEM-MM-101: A Phase I/IIa Dose Escalation Study Evaluating the Safety and Activity of Autologous CD34+ Enriched Hematopoietic Progenitor Cells Genetically Modified for Human Interferon-α2 in Multiple Myeloma Patients with Early Relapse after Intensive Front Line Therapy

Longitudinal Tracking of Acute Myeloid Leukemia Stem Cells in Xenografts and Patients By microRNA Reporters and Single Cell RNA Sequencing

Dissecting Ex Vivo Expansion of Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells By Single Cell RNA Sequencing

Microrna-126 Levels Modulate B-ALL Aggressiveness but Require Tight Regulation to Guarantee Disease Maintenance

Distinct MiR-126 Expression Describes a Non-Genetic but Functional Intra-Tumoral Heterogeneity in Primary Human B-ALL and Can be Prospectively Used to Identify Aggressive Subclones in NSG Mice

Incremental Innovation of Ex Vivo Hematopoietic Stem Cell Engineering to Expand Clinical Gene Therapy Applications

Human CD34 + Cells from Different Sources Disclose a Specific Stemness Signature

microRNA-126 Orchestrates a Stem Cell-like Program in AML and B-ALL and Can be Exploited to Dissect Disease Heterogeneity

Intrinsic Molecular Features of Human Hematopoietic Stem Cells from Different Sources Define Their Specific Functional Properties

Hoxa9/Meis1 Mediate Leukemic Programming through Microrna-155

Backtracking Leukemia Clonal Evolution from Post-Transplantation Relapse to Initial Diagnosis to Identify Founder Mutations and Mechanisms of Immune Evasion

Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance

The Challenge Of HSCs Procurement For Gene Therapy: Exploring Plerixafor As Mobilization Agent

A Mechanistic Role For Mir-126, a Hematopoietic Stem Cell Microrna, In Acute Leukemias

Off-Tumor Target Expression Levels Do Not Predict CAR-T Cell Killing: A Foundation For The Safety Of CD44v6-Targeted T Cells

CD44v6 Is Required For In Vivo Tumorigenesis Of Human AML and MM Cells: Role Of Microenvironmental Signals and Therapeutic Implications

Hematopoietic Stem Cell Expansion, without Exhaustion or Transformation, by Stable Microrna Antagonism in Vivo

Plerixafor Single Agent for Autologous Stem Cells Mobilization and Collection in Adult Thalassemic Patients: Towards the Assessment of the Suitable Hematopoietic Stem Cell Source for Gene Therapy of Beta-Thalassemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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